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The map label for this gene is ulaC [H]

Identifier: 226225195

GI number: 226225195

Start: 2688858

End: 2689292

Strand: Reverse

Name: ulaC [H]

Synonym: Lm4b_02617

Alternate gene names: 226225195

Gene position: 2689292-2688858 (Counterclockwise)

Preceding gene: 226225196

Following gene: 226225194

Centisome position: 92.33

GC content: 40.69

Gene sequence:

>435_bases
ATGTCTTTTTTGGATAAAGAGCTTGTGAATCTGCATGGATCAGCTAAGAATGCTGACGAAGCTATCGTGCAAGCAGGAGA
ATTATTAGTTAATGCAGGTTATGTGAGCGAGCAGTACGTAGAAAAAATGGTGGAATCTTATCATGAAAATGGTGCGTACT
TTGTCATTGCACCTCAAATAGCCATTCCGCACGCAAGACCAACTGATGGTGTGGAAAACTCTGCAGTATCACTAGTCGTA
CTAAAAGAAGGCGTGAATTTCGGACACGCCGCGAATGATCCCGTACGATTAGTATTCGGCCTTGCAGCAACTTCAAGTGA
GGCACATTTGAAAGTCATTCAAAAAATCGTCTCCTTGCTTAGTAACAACGATAATATTGAAAAATTGATTCATTCAGAAG
ATTACCAAGCAATTGGAGAATTAGTGGAGGGATAA

Upstream 100 bases:

>100_bases
AAAGAAAGGAATTGGGCTTTTTTAAACAGTTGCGCTACAGCTATAATAAGAGTGTAAGTTATTGATAGCGCTATCAATTA
GTTAGAAGGGATGAAGAGAT

Downstream 100 bases:

>100_bases
CGATGAAAATTTTAGCAGTATGTGGACTTGGGCAAGGAACAAGCTTAATTTTACGAATGAATGTAGAGACAGTTTTACGC
GACATGGGAGTAGATGCAGA

Product: mannitol-specific PTS enzyme IIA component

Products: protein histidine; sugar phosphate

Alternate protein names: PTS system ascorbate-specific EIIA component [H]

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MSFLDKELVNLHGSAKNADEAIVQAGELLVNAGYVSEQYVEKMVESYHENGAYFVIAPQIAIPHARPTDGVENSAVSLVV
LKEGVNFGHAANDPVRLVFGLAATSSEAHLKVIQKIVSLLSNNDNIEKLIHSEDYQAIGELVEG

Sequences:

>Translated_144_residues
MSFLDKELVNLHGSAKNADEAIVQAGELLVNAGYVSEQYVEKMVESYHENGAYFVIAPQIAIPHARPTDGVENSAVSLVV
LKEGVNFGHAANDPVRLVFGLAATSSEAHLKVIQKIVSLLSNNDNIEKLIHSEDYQAIGELVEG
>Mature_143_residues
SFLDKELVNLHGSAKNADEAIVQAGELLVNAGYVSEQYVEKMVESYHENGAYFVIAPQIAIPHARPTDGVENSAVSLVVL
KEGVNFGHAANDPVRLVFGLAATSSEAHLKVIQKIVSLLSNNDNIEKLIHSEDYQAIGELVEG

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI2367359, Length=143, Percent_Identity=33.5664335664336, Blast_Score=93, Evalue=7e-21,
Organism=Escherichia coli, GI1789302, Length=102, Percent_Identity=39.2156862745098, Blast_Score=80, Evalue=4e-17,
Organism=Escherichia coli, GI1790755, Length=140, Percent_Identity=32.1428571428571, Blast_Score=80, Evalue=4e-17,
Organism=Escherichia coli, GI1790027, Length=143, Percent_Identity=34.965034965035, Blast_Score=72, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178 [H]

Pfam domain/function: PF00359 PTS_EIIA_2 [H]

EC number: 2.7.1.69

Molecular weight: Translated: 15542; Mature: 15410

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS00372 PTS_EIIA_TYPE_2_HIS ; PS51094 PTS_EIIA_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLDKELVNLHGSAKNADEAIVQAGELLVNAGYVSEQYVEKMVESYHENGAYFVIAPQI
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEECCE
AIPHARPTDGVENSAVSLVVLKEGVNFGHAANDPVRLVFGLAATSSEAHLKVIQKIVSLL
ECCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHH
SNNDNIEKLIHSEDYQAIGELVEG
CCCCCHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure 
SFLDKELVNLHGSAKNADEAIVQAGELLVNAGYVSEQYVEKMVESYHENGAYFVIAPQI
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEECCE
AIPHARPTDGVENSAVSLVVLKEGVNFGHAANDPVRLVFGLAATSSEAHLKVIQKIVSLL
ECCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHH
SNNDNIEKLIHSEDYQAIGELVEG
CCCCCHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]