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The map label for this gene is ycjS [H]

Identifier: 226224770

GI number: 226224770

Start: 2246958

End: 2248034

Strand: Reverse

Name: ycjS [H]

Synonym: Lm4b_02188

Alternate gene names: 226224770

Gene position: 2248034-2246958 (Counterclockwise)

Preceding gene: 226224771

Following gene: 226224769

Centisome position: 77.18

GC content: 39.83

Gene sequence:

>1077_bases
ATGACATTAAAAGTTGGAATTATAGGTTGTGGAGGCATTGCAAACGGGAAGCATATGCCAAGTTTATTAAAAGCTGAGAA
AGCAGAAATGGTTGCTTTTTGCGATATCGTTTTAGAAAAAGCGGAAGCCGCAGCAAAAGAATTTGGTAGTGAAAATGCAA
GCGTATACACAAGCTATATAGAATTACTCCAAGATAAATCCATCGATGTCATCCATGTTTGTACACCAAATATTTCTCAT
GCAGAAATTTCTATTGCGGCTATGGAAGCTGGAAAGCATGTTATGTGCGAGAAACCAATGGCAAAAACAACCGAAGAAGC
GAAAAGCATGATTGAAGCTGCTAATCGTACAGGAAAAAAACTAACAATTGGTTACCAAAATAGATTCCGCAAAGACTCGG
ATTACTTGCACCAAGTTTGCGAGAACGGCGAACTAGGCGATATCTATTATGCAAAAGCAAAAGCGATTCGTCGCCGAGCT
GTACCAACTTGGGGTGTGTTTTTAGATGAAGAAGCGCAGGGTGGCGGACCACTTATTGATATTGGAACACATGCGCTTGA
TTTAACGCTTTGGATGATGGACAATTATAAACCGAAATATGTAGTAGGAAACAGTTATCATAAACTTGCCAAAAAAGAAA
ATGCAGCAAATGCATGGGGCTCATGGGATCCAAATAAATTTACTGTAGAAGATTCCGCGTTTGGTTTTATCACAATGGAA
AACGGCGCGACGATAGTATTAGAAGCAAGTTGGGCGCTTAACACACTCGATGTCGGTGAAGCAAGAACGTCTCTATCGGG
AACAGAAGGCGGCGCAGATATGGAAGACGGTTTACGAATTAACGGCGAAGCGCACAGCCAAATGTATGAAAAGAAAATTC
AATTAGAAGCAGGCGGCGTTGATTTTTATGATGGAACTGGTGATGACCCAGCGTTAATCGAAGCAGAACAATGGTTAGAA
GCAATTGAAAAAAATACAGATCCTGTTGTAAAACCAGAACAAGCACTTGTTGTAACACAAATCTTAGAAGCTATTTATGA
ATCATCGAAAACAGGACAACCAGTTTATTTTAATTAA

Upstream 100 bases:

>100_bases
GAAAGACAATATACGGGAATAATTAAGCAATAAAATAGGAAGATTTACCTCTAGTAGTTTTGTATGATGTAACTATCAAA
ACTATTGGAGGTTTTTTATT

Downstream 100 bases:

>100_bases
GGAGGAAGTGCCTTTATGAAAGCAAAAATTGCGTTACAGTTGTGGAGTGTTAAGGAAGCTTGTGAAGATGATTTCTTTGG
AACGTTAGAAAAAGTGGCGG

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MTLKVGIIGCGGIANGKHMPSLLKAEKAEMVAFCDIVLEKAEAAAKEFGSENASVYTSYIELLQDKSIDVIHVCTPNISH
AEISIAAMEAGKHVMCEKPMAKTTEEAKSMIEAANRTGKKLTIGYQNRFRKDSDYLHQVCENGELGDIYYAKAKAIRRRA
VPTWGVFLDEEAQGGGPLIDIGTHALDLTLWMMDNYKPKYVVGNSYHKLAKKENAANAWGSWDPNKFTVEDSAFGFITME
NGATIVLEASWALNTLDVGEARTSLSGTEGGADMEDGLRINGEAHSQMYEKKIQLEAGGVDFYDGTGDDPALIEAEQWLE
AIEKNTDPVVKPEQALVVTQILEAIYESSKTGQPVYFN

Sequences:

>Translated_358_residues
MTLKVGIIGCGGIANGKHMPSLLKAEKAEMVAFCDIVLEKAEAAAKEFGSENASVYTSYIELLQDKSIDVIHVCTPNISH
AEISIAAMEAGKHVMCEKPMAKTTEEAKSMIEAANRTGKKLTIGYQNRFRKDSDYLHQVCENGELGDIYYAKAKAIRRRA
VPTWGVFLDEEAQGGGPLIDIGTHALDLTLWMMDNYKPKYVVGNSYHKLAKKENAANAWGSWDPNKFTVEDSAFGFITME
NGATIVLEASWALNTLDVGEARTSLSGTEGGADMEDGLRINGEAHSQMYEKKIQLEAGGVDFYDGTGDDPALIEAEQWLE
AIEKNTDPVVKPEQALVVTQILEAIYESSKTGQPVYFN
>Mature_357_residues
TLKVGIIGCGGIANGKHMPSLLKAEKAEMVAFCDIVLEKAEAAAKEFGSENASVYTSYIELLQDKSIDVIHVCTPNISHA
EISIAAMEAGKHVMCEKPMAKTTEEAKSMIEAANRTGKKLTIGYQNRFRKDSDYLHQVCENGELGDIYYAKAKAIRRRAV
PTWGVFLDEEAQGGGPLIDIGTHALDLTLWMMDNYKPKYVVGNSYHKLAKKENAANAWGSWDPNKFTVEDSAFGFITMEN
GATIVLEASWALNTLDVGEARTSLSGTEGGADMEDGLRINGEAHSQMYEKKIQLEAGGVDFYDGTGDDPALIEAEQWLEA
IEKNTDPVVKPEQALVVTQILEAIYESSKTGQPVYFN

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Homo sapiens, GI7657212, Length=217, Percent_Identity=29.9539170506912, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1787574, Length=356, Percent_Identity=36.2359550561798, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI87081947, Length=185, Percent_Identity=26.4864864864865, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789848, Length=230, Percent_Identity=27.8260869565217, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24584727, Length=176, Percent_Identity=28.9772727272727, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24581117, Length=201, Percent_Identity=24.3781094527363, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39174; Mature: 39042

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKVGIIGCGGIANGKHMPSLLKAEKAEMVAFCDIVLEKAEAAAKEFGSENASVYTSYI
CEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ELLQDKSIDVIHVCTPNISHAEISIAAMEAGKHVMCEKPMAKTTEEAKSMIEAANRTGKK
HHHHCCCCCEEEEECCCCCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCCE
LTIGYQNRFRKDSDYLHQVCENGELGDIYYAKAKAIRRRAVPTWGVFLDEEAQGGGPLID
EEEEHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEE
IGTHALDLTLWMMDNYKPKYVVGNSYHKLAKKENAANAWGSWDPNKFTVEDSAFGFITME
ECCCEEEEEEEEECCCCCCEEECCCHHHHHHHCCCCCCCCCCCCCEEEEECCCEEEEEEC
NGATIVLEASWALNTLDVGEARTSLSGTEGGADMEDGLRINGEAHSQMYEKKIQLEAGGV
CCCEEEEEECCCCCEEECCCHHHCCCCCCCCCCCCCCEEECCHHHHHHHHHHHEEEECCE
DFYDGTGDDPALIEAEQWLEAIEKNTDPVVKPEQALVVTQILEAIYESSKTGQPVYFN
EECCCCCCCCCEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEC
>Mature Secondary Structure 
TLKVGIIGCGGIANGKHMPSLLKAEKAEMVAFCDIVLEKAEAAAKEFGSENASVYTSYI
EEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ELLQDKSIDVIHVCTPNISHAEISIAAMEAGKHVMCEKPMAKTTEEAKSMIEAANRTGKK
HHHHCCCCCEEEEECCCCCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCCE
LTIGYQNRFRKDSDYLHQVCENGELGDIYYAKAKAIRRRAVPTWGVFLDEEAQGGGPLID
EEEEHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEE
IGTHALDLTLWMMDNYKPKYVVGNSYHKLAKKENAANAWGSWDPNKFTVEDSAFGFITME
ECCCEEEEEEEEECCCCCCEEECCCHHHHHHHCCCCCCCCCCCCCEEEEECCCEEEEEEC
NGATIVLEASWALNTLDVGEARTSLSGTEGGADMEDGLRINGEAHSQMYEKKIQLEAGGV
CCCEEEEEECCCCCEEECCCHHHCCCCCCCCCCCCCCEEECCHHHHHHHHHHHEEEECCE
DFYDGTGDDPALIEAEQWLEAIEKNTDPVVKPEQALVVTQILEAIYESSKTGQPVYFN
EECCCCCCCCCEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]