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The map label for this gene is gatC [H]

Identifier: 226224701

GI number: 226224701

Start: 2175074

End: 2176423

Strand: Reverse

Name: gatC [H]

Synonym: Lm4b_02117

Alternate gene names: 226224701

Gene position: 2176423-2175074 (Counterclockwise)

Preceding gene: 226224702

Following gene: 226224700

Centisome position: 74.72

GC content: 38.07

Gene sequence:

>1350_bases
ATGGAGTCATTACAATCAGTTATACAGTTTATTTTGAACCTTGGAGCTGCCGTTTTTGTTCCAGCACTAATGATTATTAT
TGGGCTAATTGTACGAATGAAAGTAAGAGATGCAGTCAGTGCGGGGATTATTCTAGGGGTTGCTTTCCTTGGAATGAACA
TCGTTATCGGCTTTATGATTGAAGCTTTAACACCAGCTGCACAAGGACTAGCTGAGAGAACAGGGATTAATTTAAGCATC
TTAGATGGAGGCTGGACATCGATGGCAACACTTGCTTGGGCATGGCCATTTGCCTTCTTGATGTTCCCGCTACAACTAGG
TATTAACGCAATTATGCTCGTTATCAATAAAACCAAAACCTTAAACGTCGATTTATGGAATGTTTGGGGGAAAATTTTAA
CAGCCGTACTTATTATCGGTGTAACACAAAATGTTTACTTAGCATTTATTGTTGCCGGAATTCAAATTGTTACAGAACTA
ATTCTATGTGATGCCAACCAACGTCAAATTCAAGAGTTAAATGGAATTCCAGGTGTAACCGTTTCTCACGGTATGATGAT
TTTCTGTATTTTCTTAATGCCGCTTGACTGGTTACTGAAAAAAATTCCAGCACTTCGTAAAGACATGGATGCCAATGCGT
TAAAAGATAAAATTGGTATTTTTGCAGAAAACCATGTGATGGGCTTTATTATCGGTGGACTTCTGGGGATTGCAGCTGGT
TATGATGTTGCGAAAACCTTGATGTTAGCCATGCAAGCTGCAGCAGCATTAACTCTTTTCCCGATGGTTGCAAAACTATT
TATGCAAGCTCTTTCGCCACTATCTGATGGTATTTCTGAGTTCATGAAACGTAAATTTAAAAACCGTGAATTGTTTATTG
GGCTAGATTGGCCGATTTTAGCAGGATGTAGTGAAGTTTGGGTAGCAATCGTTCTGATGGTTCCAGTTACACTTATCTTT
GCGCTTATTTTACCAGGAAATGGCGTATTACCGTTCGCTGGGATTTTAAATATTTCTTTATGCGCACCAGCACTTATCGT
AACAGGTGGAAACTTAATTCGTATGATTATCCTTGGAACAATTACCACACCGATTTTCTTATATGTATCTACTTTCTTCG
CTGGAACAATTACGGATTTAGCGCATTCAACAGGCGCAATTTCGCTAAAAGCTGGACAACAAATTACATGGAGTACACTT
GAATATCCAGTGTTCCGTTATATCTTTGCAGAAGCAAGTCAGTTTACTATTTTAGGCTTTATTTTTGTCGCAATTTGGGT
AGTATTACTAGTATTCTATGTGAAAATGATGAAAAAACGAACAATTGAACTAGAAAAAGCTAGCTCTTAA

Upstream 100 bases:

>100_bases
GAATGGTATTGCCTTCTTAACAGGCATGGGCATGGACGAAGAAACAGAAAAATTACTTAACGCCTTAAAATAAACCAGAT
AAAACAGGGAGCGTGAAAAA

Downstream 100 bases:

>100_bases
GAAATAGGAGTGATGAGATGATTTACACGATAACATTAAATCCAGCCATTGACCGGTTGCTTTTCATTCAAGGAGAGTTA
GAAAAAAGGAAGACTAATCG

Product: PTS system galactitol-specific enzyme IIC component

Products: galactitol-1-phosphate [Cytoplasm]; pyruvate [C]

Alternate protein names: EIIC-Gat; PTS system galactitol-specific EIIC component [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MESLQSVIQFILNLGAAVFVPALMIIIGLIVRMKVRDAVSAGIILGVAFLGMNIVIGFMIEALTPAAQGLAERTGINLSI
LDGGWTSMATLAWAWPFAFLMFPLQLGINAIMLVINKTKTLNVDLWNVWGKILTAVLIIGVTQNVYLAFIVAGIQIVTEL
ILCDANQRQIQELNGIPGVTVSHGMMIFCIFLMPLDWLLKKIPALRKDMDANALKDKIGIFAENHVMGFIIGGLLGIAAG
YDVAKTLMLAMQAAAALTLFPMVAKLFMQALSPLSDGISEFMKRKFKNRELFIGLDWPILAGCSEVWVAIVLMVPVTLIF
ALILPGNGVLPFAGILNISLCAPALIVTGGNLIRMIILGTITTPIFLYVSTFFAGTITDLAHSTGAISLKAGQQITWSTL
EYPVFRYIFAEASQFTILGFIFVAIWVVLLVFYVKMMKKRTIELEKASS

Sequences:

>Translated_449_residues
MESLQSVIQFILNLGAAVFVPALMIIIGLIVRMKVRDAVSAGIILGVAFLGMNIVIGFMIEALTPAAQGLAERTGINLSI
LDGGWTSMATLAWAWPFAFLMFPLQLGINAIMLVINKTKTLNVDLWNVWGKILTAVLIIGVTQNVYLAFIVAGIQIVTEL
ILCDANQRQIQELNGIPGVTVSHGMMIFCIFLMPLDWLLKKIPALRKDMDANALKDKIGIFAENHVMGFIIGGLLGIAAG
YDVAKTLMLAMQAAAALTLFPMVAKLFMQALSPLSDGISEFMKRKFKNRELFIGLDWPILAGCSEVWVAIVLMVPVTLIF
ALILPGNGVLPFAGILNISLCAPALIVTGGNLIRMIILGTITTPIFLYVSTFFAGTITDLAHSTGAISLKAGQQITWSTL
EYPVFRYIFAEASQFTILGFIFVAIWVVLLVFYVKMMKKRTIELEKASS
>Mature_449_residues
MESLQSVIQFILNLGAAVFVPALMIIIGLIVRMKVRDAVSAGIILGVAFLGMNIVIGFMIEALTPAAQGLAERTGINLSI
LDGGWTSMATLAWAWPFAFLMFPLQLGINAIMLVINKTKTLNVDLWNVWGKILTAVLIIGVTQNVYLAFIVAGIQIVTEL
ILCDANQRQIQELNGIPGVTVSHGMMIFCIFLMPLDWLLKKIPALRKDMDANALKDKIGIFAENHVMGFIIGGLLGIAAG
YDVAKTLMLAMQAAAALTLFPMVAKLFMQALSPLSDGISEFMKRKFKNRELFIGLDWPILAGCSEVWVAIVLMVPVTLIF
ALILPGNGVLPFAGILNISLCAPALIVTGGNLIRMIILGTITTPIFLYVSTFFAGTITDLAHSTGAISLKAGQQITWSTL
EYPVFRYIFAEASQFTILGFIFVAIWVVLLVFYVKMMKKRTIELEKASS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3775

COG function: function code G; Phosphotransferase system, galactitol-specific IIC component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788408, Length=409, Percent_Identity=33.2518337408313, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1790758, Length=406, Percent_Identity=31.2807881773399, Blast_Score=187, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013853
- InterPro:   IPR013014
- InterPro:   IPR004703 [H]

Pfam domain/function: PF03611 EIIC-GAT [H]

EC number: NA

Molecular weight: Translated: 48894; Mature: 48894

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLQSVIQFILNLGAAVFVPALMIIIGLIVRMKVRDAVSAGIILGVAFLGMNIVIGFMI
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EALTPAAQGLAERTGINLSILDGGWTSMATLAWAWPFAFLMFPLQLGINAIMLVINKTKT
HHHCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCHHHHEEEEECCEE
LNVDLWNVWGKILTAVLIIGVTQNVYLAFIVAGIQIVTELILCDANQRQIQELNGIPGVT
EEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCH
VSHGMMIFCIFLMPLDWLLKKIPALRKDMDANALKDKIGIFAENHVMGFIIGGLLGIAAG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
YDVAKTLMLAMQAAAALTLFPMVAKLFMQALSPLSDGISEFMKRKFKNRELFIGLDWPIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHH
AGCSEVWVAIVLMVPVTLIFALILPGNGVLPFAGILNISLCAPALIVTGGNLIRMIILGT
HCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ITTPIFLYVSTFFAGTITDLAHSTGAISLKAGQQITWSTLEYPVFRYIFAEASQFTILGF
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEHHHHHHHHHHHHHHCCCHHHHHHH
IFVAIWVVLLVFYVKMMKKRTIELEKASS
HHHHHHHHHHHHHHHHHHHHHCCHHCCCC
>Mature Secondary Structure
MESLQSVIQFILNLGAAVFVPALMIIIGLIVRMKVRDAVSAGIILGVAFLGMNIVIGFMI
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EALTPAAQGLAERTGINLSILDGGWTSMATLAWAWPFAFLMFPLQLGINAIMLVINKTKT
HHHCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCHHHHEEEEECCEE
LNVDLWNVWGKILTAVLIIGVTQNVYLAFIVAGIQIVTELILCDANQRQIQELNGIPGVT
EEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCH
VSHGMMIFCIFLMPLDWLLKKIPALRKDMDANALKDKIGIFAENHVMGFIIGGLLGIAAG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
YDVAKTLMLAMQAAAALTLFPMVAKLFMQALSPLSDGISEFMKRKFKNRELFIGLDWPIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHH
AGCSEVWVAIVLMVPVTLIFALILPGNGVLPFAGILNISLCAPALIVTGGNLIRMIILGT
HCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ITTPIFLYVSTFFAGTITDLAHSTGAISLKAGQQITWSTLEYPVFRYIFAEASQFTILGF
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEHHHHHHHHHHHHHHCCCHHHHHHH
IFVAIWVVLLVFYVKMMKKRTIELEKASS
HHHHHHHHHHHHHHHHHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: phosphoenolpyruvate; galactitol [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + galactitol [Periplasm] = galactitol-1-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]