Click here to switch to the map view.

The map label for this gene is divIVA

Identifier: 226224617

GI number: 226224617

Start: 2088960

End: 2089487

Strand: Reverse

Name: divIVA

Synonym: Lm4b_02032

Alternate gene names: 226224617

Gene position: 2089487-2088960 (Counterclockwise)

Preceding gene: 226224618

Following gene: 226224616

Centisome position: 71.74

GC content: 36.36

Gene sequence:

>528_bases
ATGCCATTATCGCCGCTGGATATACATAACAAAGAGTTTACCCGTGGTTTTAGAGGTTATGACGAAGACGAAGTAAATGA
CTTCCTCGATCAAATCATTAAAGATTATGAACAAGTTATTAAAGAGAAAAAGCGTATTGAGGACACTTTAAATAATAGTG
AAGAACGTTTAGGTCATTTTACAAACATTGAAGAAACATTAAACAAATCATTAATCGTGGCACAAACAGCTGCCGAAGAA
GTGAAAGCTTCCGCTGAAAAAGAAGCAAAACTTATTATCCGTGAAGCTGAAAAAAATGCAGACCGAATTTTAAGCGACTC
ACTTTCTAAAGCTCGTAAAATCGCGATTGAAATTGAAGACCTAAAACGTCAATCTAAAGTATTCCGCGAGCGTCTGCGTA
TGTTAGTAGAAGCGCAAATGGATTTAATTAAAAGTGAAGATTGGCAGCAAATGATGGCTTACGATGTAGATGCAACAGAA
TTAGCGTCTATTAAAGAAGTCGAAGCTGCTGAATCAGAAGAACGTTAA

Upstream 100 bases:

>100_bases
TCTAACCATTTTTCAATATAAATTCTAGGAAAAAGCTAGTAACTATGGTAGAATGTATGTTAGGTATTTATAAACAAATA
GTCGTATGGAGGTGCTAGAT

Downstream 100 bases:

>100_bases
AAACGATTATAAGAGACAAGTAAATTTTTTAGACAAAGGATATGAAGCGAGTTGGTAAATGGTGCGAGACCAACTATCCT
CTAAAAAATAGAAATCACTC

Product: cell-division initiation protein (septum placement)

Products: NA

Alternate protein names: Cell division initiation protein divIVA; Minicell-associated protein divIVA [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MPLSPLDIHNKEFTRGFRGYDEDEVNDFLDQIIKDYEQVIKEKKRIEDTLNNSEERLGHFTNIEETLNKSLIVAQTAAEE
VKASAEKEAKLIIREAEKNADRILSDSLSKARKIAIEIEDLKRQSKVFRERLRMLVEAQMDLIKSEDWQQMMAYDVDATE
LASIKEVEAAESEER

Sequences:

>Translated_175_residues
MPLSPLDIHNKEFTRGFRGYDEDEVNDFLDQIIKDYEQVIKEKKRIEDTLNNSEERLGHFTNIEETLNKSLIVAQTAAEE
VKASAEKEAKLIIREAEKNADRILSDSLSKARKIAIEIEDLKRQSKVFRERLRMLVEAQMDLIKSEDWQQMMAYDVDATE
LASIKEVEAAESEER
>Mature_174_residues
PLSPLDIHNKEFTRGFRGYDEDEVNDFLDQIIKDYEQVIKEKKRIEDTLNNSEERLGHFTNIEETLNKSLIVAQTAAEEV
KASAEKEAKLIIREAEKNADRILSDSLSKARKIAIEIEDLKRQSKVFRERLRMLVEAQMDLIKSEDWQQMMAYDVDATEL
ASIKEVEAAESEER

Specific function: May act as a pilot protein, directing minCD to the polar septation sites or by inhibiting minCD at the midcell site of division. Required for polar localization of the chromosome during sporulation [H]

COG id: COG3599

COG function: function code D; Cell division initiation protein

Gene ontology:

Cell location: Cytoplasm. Note=Localized at the cell division site and found exclusively at the cell pole during sporulation [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gpsB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007793
- InterPro:   IPR019933 [H]

Pfam domain/function: PF05103 DivIVA [H]

EC number: NA

Molecular weight: Translated: 20333; Mature: 20202

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSPLDIHNKEFTRGFRGYDEDEVNDFLDQIIKDYEQVIKEKKRIEDTLNNSEERLGHF
CCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
TNIEETLNKSLIVAQTAAEEVKASAEKEAKLIIREAEKNADRILSDSLSKARKIAIEIED
CCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKRQSKVFRERLRMLVEAQMDLIKSEDWQQMMAYDVDATELASIKEVEAAESEER
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PLSPLDIHNKEFTRGFRGYDEDEVNDFLDQIIKDYEQVIKEKKRIEDTLNNSEERLGHF
CCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
TNIEETLNKSLIVAQTAAEEVKASAEKEAKLIIREAEKNADRILSDSLSKARKIAIEIED
CCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKRQSKVFRERLRMLVEAQMDLIKSEDWQQMMAYDVDATELASIKEVEAAESEER
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9045828; 9219999; 9384377 [H]