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The map label for this gene is yajO [H]

Identifier: 226224603

GI number: 226224603

Start: 2065761

End: 2066756

Strand: Reverse

Name: yajO [H]

Synonym: Lm4b_02017

Alternate gene names: 226224603

Gene position: 2066756-2065761 (Counterclockwise)

Preceding gene: 226224604

Following gene: 226224602

Centisome position: 70.96

GC content: 40.46

Gene sequence:

>996_bases
ATGGAATATGTTAAATTTGGCAACACTGGCATGGATGTTTCGAAAATCTGTTTAGGGACAATGGGGTTCGGTGATAAAGA
CAAATGGATTCATAAATGGGTTTTGAACGAAGCGAACAGTCGCCCTATCATAAAAAAAGCACTCGATTTAGGCATAAATT
TCTTTGATACGGCGAATATTTATTCTTATGGTGAAAGTGAAAAAATCGTTGGACGTGCACTAAAAGACTATGCTAACCGC
GATGATGTTGTGTTAGCAACCAAGGTGCAACAAACAATGCGCCCGGATCGCCCGAATAGTGGTGGTTTATCCAGGAAAAC
TATTTTGAGCGAAATCGACCATAGTTTAAAACGCTTAGAAACGGATTATGTAGATTTATATATCATTCACCGTTTTGATG
AAAATACGCCAATCGAAGAAACAATGGAAGCCTTACACGATGTCGTTAAGTCCGGGAAAGCGCGTTACATTGGAGCGAGT
GCGATGTATGCTTGGCAGTTTCAAAAAGCACAACGCGTCGCAGAAAGAAACGGTTGGACAAAATTCGTTTCCATGCAAAA
TCATTATAATATGATTTACCGGGAAGAAGAGCGAGAAATGATTCCGTTTTGTCGCGATGAAAAAATTGCGATTACGCCAT
ACAGCCCGCTAGCATCAGGACGATTAACGCGAGATTTGAATGAAACAACCAATCGTTCCGAAACGGATCCAGTTCAAAAA
TCCAAATACGATGACATGATGAATGCAGATAGAGGTATTATTGAACGTGTGGCTGAACTTGCGGAAACGCATCAAGTATC
TCGAGATAAGATTGCTTTAGCGTGGCTATTAAATAAAGATGAAATCACTTCGCCAATCATCGGTGCACAAAAAGAAAGTC
ATCTGGAAAGCGCGGTAGAGGCGCTAAATATTCAATTAACGGCAGCGGAAGTTAACTATCTAGAAGAATTATATATCCCG
CACCCAGTAGTTGGAGCACTACCTACAACTAAATAA

Upstream 100 bases:

>100_bases
CGGATTTCCCGAGAGATTTTTTTATAGTTAAAGGTTGACTTGGAGTGGACTTCAAGGTTTATGCTGTAATAGTACTAGAA
ATTAACTAGGAGGGTTTTGA

Downstream 100 bases:

>100_bases
TCAAATGGAGCATGAGTTGGATGGAAAAATCTGACTCATGCTTTTTTTTATGTAAAAAGACTATTGACAAACAAAATGCA
ACCGTTTACAATGAAGTGGT

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MEYVKFGNTGMDVSKICLGTMGFGDKDKWIHKWVLNEANSRPIIKKALDLGINFFDTANIYSYGESEKIVGRALKDYANR
DDVVLATKVQQTMRPDRPNSGGLSRKTILSEIDHSLKRLETDYVDLYIIHRFDENTPIEETMEALHDVVKSGKARYIGAS
AMYAWQFQKAQRVAERNGWTKFVSMQNHYNMIYREEEREMIPFCRDEKIAITPYSPLASGRLTRDLNETTNRSETDPVQK
SKYDDMMNADRGIIERVAELAETHQVSRDKIALAWLLNKDEITSPIIGAQKESHLESAVEALNIQLTAAEVNYLEELYIP
HPVVGALPTTK

Sequences:

>Translated_331_residues
MEYVKFGNTGMDVSKICLGTMGFGDKDKWIHKWVLNEANSRPIIKKALDLGINFFDTANIYSYGESEKIVGRALKDYANR
DDVVLATKVQQTMRPDRPNSGGLSRKTILSEIDHSLKRLETDYVDLYIIHRFDENTPIEETMEALHDVVKSGKARYIGAS
AMYAWQFQKAQRVAERNGWTKFVSMQNHYNMIYREEEREMIPFCRDEKIAITPYSPLASGRLTRDLNETTNRSETDPVQK
SKYDDMMNADRGIIERVAELAETHQVSRDKIALAWLLNKDEITSPIIGAQKESHLESAVEALNIQLTAAEVNYLEELYIP
HPVVGALPTTK
>Mature_331_residues
MEYVKFGNTGMDVSKICLGTMGFGDKDKWIHKWVLNEANSRPIIKKALDLGINFFDTANIYSYGESEKIVGRALKDYANR
DDVVLATKVQQTMRPDRPNSGGLSRKTILSEIDHSLKRLETDYVDLYIIHRFDENTPIEETMEALHDVVKSGKARYIGAS
AMYAWQFQKAQRVAERNGWTKFVSMQNHYNMIYREEEREMIPFCRDEKIAITPYSPLASGRLTRDLNETTNRSETDPVQK
SKYDDMMNADRGIIERVAELAETHQVSRDKIALAWLLNKDEITSPIIGAQKESHLESAVEALNIQLTAAEVNYLEELYIP
HPVVGALPTTK

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=314, Percent_Identity=27.7070063694268, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI4504825, Length=311, Percent_Identity=28.2958199356913, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI27436964, Length=333, Percent_Identity=26.4264264264264, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI27436962, Length=328, Percent_Identity=26.5243902439024, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI27436966, Length=333, Percent_Identity=26.1261261261261, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI27436971, Length=335, Percent_Identity=27.1641791044776, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI223718702, Length=211, Percent_Identity=30.3317535545024, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI41152114, Length=206, Percent_Identity=31.5533980582524, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI41327764, Length=181, Percent_Identity=32.5966850828729, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI223718708, Length=150, Percent_Identity=30.6666666666667, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI87081735, Length=325, Percent_Identity=54.7692307692308, Blast_Score=353, Evalue=8e-99,
Organism=Escherichia coli, GI1789375, Length=316, Percent_Identity=34.1772151898734, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1788070, Length=333, Percent_Identity=30.6306306306306, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1789199, Length=358, Percent_Identity=25.6983240223464, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1788081, Length=280, Percent_Identity=28.2142857142857, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786400, Length=266, Percent_Identity=27.8195488721804, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787674, Length=271, Percent_Identity=25.830258302583, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI48994888, Length=311, Percent_Identity=24.7588424437299, Blast_Score=72, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6325169, Length=337, Percent_Identity=40.6528189910979, Blast_Score=245, Evalue=9e-66,
Organism=Saccharomyces cerevisiae, GI6319958, Length=303, Percent_Identity=30.3630363036304, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6323998, Length=336, Percent_Identity=28.5714285714286, Blast_Score=139, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6319951, Length=324, Percent_Identity=26.8518518518519, Blast_Score=123, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6322615, Length=261, Percent_Identity=30.6513409961686, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320079, Length=288, Percent_Identity=28.4722222222222, Blast_Score=76, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6321052, Length=153, Percent_Identity=28.1045751633987, Blast_Score=69, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24640980, Length=348, Percent_Identity=24.7126436781609, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI45549126, Length=349, Percent_Identity=24.9283667621776, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24646155, Length=330, Percent_Identity=26.3636363636364, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24646159, Length=322, Percent_Identity=25.776397515528, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37799; Mature: 37799

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYVKFGNTGMDVSKICLGTMGFGDKDKWIHKWVLNEANSRPIIKKALDLGINFFDTANI
CCEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCEEECCCH
YSYGESEKIVGRALKDYANRDDVVLATKVQQTMRPDRPNSGGLSRKTILSEIDHSLKRLE
HCCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHC
TDYVDLYIIHRFDENTPIEETMEALHDVVKSGKARYIGASAMYAWQFQKAQRVAERNGWT
CCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCCCE
KFVSMQNHYNMIYREEEREMIPFCRDEKIAITPYSPLASGRLTRDLNETTNRSETDPVQK
EEEEHHHHHHHEEECCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHCCCCCCCCHHH
SKYDDMMNADRGIIERVAELAETHQVSRDKIALAWLLNKDEITSPIIGAQKESHLESAVE
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHCCCCHHCCCHHHHHHHHHH
ALNIQLTAAEVNYLEELYIPHPVVGALPTTK
HHHEEEEHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MEYVKFGNTGMDVSKICLGTMGFGDKDKWIHKWVLNEANSRPIIKKALDLGINFFDTANI
CCEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCEEECCCH
YSYGESEKIVGRALKDYANRDDVVLATKVQQTMRPDRPNSGGLSRKTILSEIDHSLKRLE
HCCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHC
TDYVDLYIIHRFDENTPIEETMEALHDVVKSGKARYIGASAMYAWQFQKAQRVAERNGWT
CCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCCCE
KFVSMQNHYNMIYREEEREMIPFCRDEKIAITPYSPLASGRLTRDLNETTNRSETDPVQK
EEEEHHHHHHHEEECCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHCCCCCCCCHHH
SKYDDMMNADRGIIERVAELAETHQVSRDKIALAWLLNKDEITSPIIGAQKESHLESAVE
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHCCCCHHCCCHHHHHHHHHH
ALNIQLTAAEVNYLEELYIPHPVVGALPTTK
HHHEEEEHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]