Click here to switch to the map view.

The map label for this gene is fhuG

Identifier: 226224562

GI number: 226224562

Start: 2025602

End: 2026624

Strand: Reverse

Name: fhuG

Synonym: Lm4b_01976

Alternate gene names: 226224562

Gene position: 2026624-2025602 (Counterclockwise)

Preceding gene: 226224563

Following gene: 226224561

Centisome position: 69.58

GC content: 42.42

Gene sequence:

>1023_bases
ATGTATATGACAACGGCAGAAAAACGAAAAAAATCGCGGCGAGTTTGGACGTTAATTATTTTAAGCGTGTTAATTTTTTG
TACATTTACATATAGTGTCAATGCTGGTTATTCGAAATTGCCATTTTTGGAAGTGATTAAGTCGTTTTTTGGAATGGCGG
ACGCGGGAACACAACTTATTGTGACGGAGTTTCGTTTGCCACGGATAGTTATTGCGCTATTGGTTGGTGCAGGTCTTGCG
GTTTCAGGAACAATCCTACAAGGGATTTCTGGAAACGGATTAGCTGATCCGGGAATTCTTGGGATTAATAATGGCGCGGG
ACTTGCGGTTATGCTTTATATTTCCTTTTTTCCTTCCACGATGGACGTTCCGGTGTTATTTATGCCATTTATTGGATTTG
TCGGGGCAATTTTAACTGCGTTTGTTGTTTACGGACTTTCTTATAGTAGAAGCGAAGGATTGTTGCCTAATCGATTGCTT
CTTACGGGGATTGCTGTTGCGGCGGCGATTGCGGCACTTATCACACTGCTTACGGTTCGGCTTGATCCGCAAAATTATCA
ACGCTATGCTGAATGGATGGCAGGAAATATTTGGGCTTCAAGCTGGCAATATGTTTATGCTCTTTTGCCATGGCTTATTG
TTTTAGGTGCAATTGCTTTTATGAAAGTAAAGACGTTGGATGTGCTCTCTTTTGGAGACCAAGTGGCAACCGGACTCGGC
GTTCGGGTTGAGCGAGAAAAATTTGTGCTTTTAATAGTAGCAGTTGGTTTGGCAGCTGCTTGTGTATCCGTTAGTGGCGG
TATTGCATTTATTGGTCTAATTGGTCCGCATATTGCTAGAAAATTAGTTGGATCCGCACATCGCTGGGTGATGGTAACGG
CGGCACTTTCTGGAGGGCTACTATTATTACTTGCGGATACGATTGGACGATTGATTATTCAACCATCCGAAATATTTGCT
GGTATCGTTGTGGCAATTATCGGTGCACCTTATTTCTTGTTCTTGCTTGCAAAAGCTAAATAA

Upstream 100 bases:

>100_bases
CAATCAATCCGCCATATGAAACGCCAATCAGTGTTATTTTTGCATTAATCGGGGTTCCTTTCTTCTTATATGTAGCACGT
AAAGAAAGGAGGAACTTATA

Downstream 100 bases:

>100_bases
TAATTATTATTGATAACGAGAAATTAATTAGTAATTGATAATCATTGTAGACAGCCTATTGCTTTTATGATATCTTAGTA
AACATAAGCAATAGGAATTG

Product: ferrichrome ABC transporter (permease)

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MYMTTAEKRKKSRRVWTLIILSVLIFCTFTYSVNAGYSKLPFLEVIKSFFGMADAGTQLIVTEFRLPRIVIALLVGAGLA
VSGTILQGISGNGLADPGILGINNGAGLAVMLYISFFPSTMDVPVLFMPFIGFVGAILTAFVVYGLSYSRSEGLLPNRLL
LTGIAVAAAIAALITLLTVRLDPQNYQRYAEWMAGNIWASSWQYVYALLPWLIVLGAIAFMKVKTLDVLSFGDQVATGLG
VRVEREKFVLLIVAVGLAAACVSVSGGIAFIGLIGPHIARKLVGSAHRWVMVTAALSGGLLLLLADTIGRLIIQPSEIFA
GIVVAIIGAPYFLFLLAKAK

Sequences:

>Translated_340_residues
MYMTTAEKRKKSRRVWTLIILSVLIFCTFTYSVNAGYSKLPFLEVIKSFFGMADAGTQLIVTEFRLPRIVIALLVGAGLA
VSGTILQGISGNGLADPGILGINNGAGLAVMLYISFFPSTMDVPVLFMPFIGFVGAILTAFVVYGLSYSRSEGLLPNRLL
LTGIAVAAAIAALITLLTVRLDPQNYQRYAEWMAGNIWASSWQYVYALLPWLIVLGAIAFMKVKTLDVLSFGDQVATGLG
VRVEREKFVLLIVAVGLAAACVSVSGGIAFIGLIGPHIARKLVGSAHRWVMVTAALSGGLLLLLADTIGRLIIQPSEIFA
GIVVAIIGAPYFLFLLAKAK
>Mature_340_residues
MYMTTAEKRKKSRRVWTLIILSVLIFCTFTYSVNAGYSKLPFLEVIKSFFGMADAGTQLIVTEFRLPRIVIALLVGAGLA
VSGTILQGISGNGLADPGILGINNGAGLAVMLYISFFPSTMDVPVLFMPFIGFVGAILTAFVVYGLSYSRSEGLLPNRLL
LTGIAVAAAIAALITLLTVRLDPQNYQRYAEWMAGNIWASSWQYVYALLPWLIVLGAIAFMKVKTLDVLSFGDQVATGLG
VRVEREKFVLLIVAVGLAAACVSVSGGIAFIGLIGPHIARKLVGSAHRWVMVTAALSGGLLLLLADTIGRLIIQPSEIFA
GIVVAIIGAPYFLFLLAKAK

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=311, Percent_Identity=35.3697749196142, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1786805, Length=306, Percent_Identity=35.9477124183007, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1790741, Length=285, Percent_Identity=34.7368421052632, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786804, Length=308, Percent_Identity=33.7662337662338, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1786347, Length=276, Percent_Identity=34.0579710144928, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1788004, Length=282, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36365; Mature: 36365

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYMTTAEKRKKSRRVWTLIILSVLIFCTFTYSVNAGYSKLPFLEVIKSFFGMADAGTQLI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHCCCCCCCEEE
VTEFRLPRIVIALLVGAGLAVSGTILQGISGNGLADPGILGINNGAGLAVMLYISFFPST
EEHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCC
MDVPVLFMPFIGFVGAILTAFVVYGLSYSRSEGLLPNRLLLTGIAVAAAIAALITLLTVR
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHE
LDPQNYQRYAEWMAGNIWASSWQYVYALLPWLIVLGAIAFMKVKTLDVLSFGDQVATGLG
ECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCC
VRVEREKFVLLIVAVGLAAACVSVSGGIAFIGLIGPHIARKLVGSAHRWVMVTAALSGGL
CEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHEEEEEHHCCCH
LLLLADTIGRLIIQPSEIFAGIVVAIIGAPYFLFLLAKAK
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYMTTAEKRKKSRRVWTLIILSVLIFCTFTYSVNAGYSKLPFLEVIKSFFGMADAGTQLI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHCCCCCCCEEE
VTEFRLPRIVIALLVGAGLAVSGTILQGISGNGLADPGILGINNGAGLAVMLYISFFPST
EEHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCC
MDVPVLFMPFIGFVGAILTAFVVYGLSYSRSEGLLPNRLLLTGIAVAAAIAALITLLTVR
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHE
LDPQNYQRYAEWMAGNIWASSWQYVYALLPWLIVLGAIAFMKVKTLDVLSFGDQVATGLG
ECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCC
VRVEREKFVLLIVAVGLAAACVSVSGGIAFIGLIGPHIARKLVGSAHRWVMVTAALSGGL
CEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHEEEEEHHCCCH
LLLLADTIGRLIIQPSEIFAGIVVAIIGAPYFLFLLAKAK
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]