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The map label for this gene is hup

Identifier: 226224538

GI number: 226224538

Start: 1996183

End: 1996458

Strand: Reverse

Name: hup

Synonym: Lm4b_01951

Alternate gene names: 226224538

Gene position: 1996458-1996183 (Counterclockwise)

Preceding gene: 226224539

Following gene: 226224537

Centisome position: 68.54

GC content: 37.32

Gene sequence:

>276_bases
ATGGCAAATAAAACTGATTTAGTAAATAGCGTTGCTGAACTAGCTGATCTTTCTAAAAAAGACGCAGCGAAAGCAGTAGA
AGCTGTATTCGAAACTATTCAAACTTCTTTATCTAAAGGTGAAAAAGTTCAATTAATCGGATTTGGTAACTTTGAAGTAC
GTGAACGTGCTGCCCGTAAAGGTCGTAACCCTCGTACTAAAGAAGAAATCGACATCCCTGCAAGTAAAGTACCAGCTTTC
AAACCTGGTAAAGCGCTTAAAGAAGCTGTTAAATAA

Upstream 100 bases:

>100_bases
AGATTTCCAAATTGATTTTTGTTTTTGGAAAAAAAGAGAAATACAGGTATATCTTGTACCTGCTTATTTTGTAGTATTCT
GTGAAGGAGGTGAAAACACA

Downstream 100 bases:

>100_bases
GCTACATAGACTTTTAAGCACTAACTCTAGTCTGGCCTTAATTTTATAATTAAGCTAGGCTAGTTTTTTTATGCCCATTT
TTAGTGGTTTTCTGTTTTAG

Product: non-specific DNA-binding protein HU

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 91; Mature: 90

Protein sequence:

>91_residues
MANKTDLVNSVAELADLSKKDAAKAVEAVFETIQTSLSKGEKVQLIGFGNFEVRERAARKGRNPRTKEEIDIPASKVPAF
KPGKALKEAVK

Sequences:

>Translated_91_residues
MANKTDLVNSVAELADLSKKDAAKAVEAVFETIQTSLSKGEKVQLIGFGNFEVRERAARKGRNPRTKEEIDIPASKVPAF
KPGKALKEAVK
>Mature_90_residues
ANKTDLVNSVAELADLSKKDAAKAVEAVFETIQTSLSKGEKVQLIGFGNFEVRERAARKGRNPRTKEEIDIPASKVPAFK
PGKALKEAVK

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=88, Percent_Identity=52.2727272727273, Blast_Score=99, Evalue=5e-23,
Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=55.0561797752809, Blast_Score=97, Evalue=2e-22,
Organism=Escherichia coli, GI1788005, Length=74, Percent_Identity=51.3513513513513, Blast_Score=80, Evalue=4e-17,
Organism=Escherichia coli, GI1787141, Length=87, Percent_Identity=34.4827586206897, Blast_Score=69, Evalue=6e-14,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9882; Mature: 9751

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANKTDLVNSVAELADLSKKDAAKAVEAVFETIQTSLSKGEKVQLIGFGNFEVRERAARK
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHC
GRNPRTKEEIDIPASKVPAFKPGKALKEAVK
CCCCCCCCCCCCCHHHCCCCCCCHHHHHHCC
>Mature Secondary Structure 
ANKTDLVNSVAELADLSKKDAAKAVEAVFETIQTSLSKGEKVQLIGFGNFEVRERAARK
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHC
GRNPRTKEEIDIPASKVPAFKPGKALKEAVK
CCCCCCCCCCCCCHHHCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA