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The map label for this gene is ctpA [H]

Identifier: 226224454

GI number: 226224454

Start: 1913190

End: 1914680

Strand: Reverse

Name: ctpA [H]

Synonym: Lm4b_01867

Alternate gene names: 226224454

Gene position: 1914680-1913190 (Counterclockwise)

Preceding gene: 226224455

Following gene: 226224453

Centisome position: 65.74

GC content: 38.03

Gene sequence:

>1491_bases
ATGGAAGAATCCCCACAAAACGAACCAAATAACGTGGAGAAAGACGAAGAACAAAAAGCAAAACCCGGCAATGGTTATAT
AAAAATGAAGTTATTCCCATTTATAATGCTACTATTCGCTTTTGTTTTTGTGACGGCATTAGTGACTACAATCGTAATGT
CTTTAGGGGATGACAAGCAAGTAAAAGTGAGCATTCCAGAACGAAAAGAATTTACCAAGCTCTACGATGTATACGACGAA
ATTACAAGCAAATATTATAAAGATACAAAATCTACAACGATGATAGATGGAGCAATAAATGGTATGGTCAATTCATTAGA
TGATCCATATTCCACATTTATGTCGAAAAAAGAATCTTCAGAGTTTAACGATACAATTTCTGCTAGTTTTGAAGGTATTG
GTGCTGAGATTCAAGAAAAAGATGGGGCTATTGTAATAGTTTCGCCAATCAAAAACTCTCCAGCCGAAAAAGCTGGTTTA
CGGCCACAAGATATTATTACACAAGTAGATGGGAAGTCTGTTAAAGGCGATACAGCAACAGAAGCAACACAAAAAATCCG
TGGTGAAAAAGGCACCAAAGTAACCCTGACCATTCAACGTTCCAACGAAGATAAACCATTTGATGTCACGATTACTCGTG
ATGAAATTCCAATCGAAACGGTGTACAAAGAAATGGGCAGTGACAAAATTGCGCACGTCACCATTAGTACATTTTCAGAA
ACAACCTATGATGAGCTTGAAAAGGCATTGAAATCCCTTGAAAAAGATGGCATGAAGGGCCTTGTTCTTGACCTGCGAGG
AAATCCTGGTGGGTTACTTGATCAAGCAGTTTCGATTTCTAGCCTCTTTGTTCCCGATGGCAAAATTGTTGTACAAGAGC
AGGACAAAGACGGTGATAAATCAGCCATTAAAGCGGATAGTAGCTCACATGGAGATTATAAAGTAAAAGTACCAACAACT
ATGTTAATAGATGGTGGTAGTGCAAGTGCTTCAGAAATCCTTGCTGCTGCAGCAAAAGAATCTGGTGGCATTAAACTTGT
CGGCACGAAATCATTTGGTAAAGGTACGGTCCAAACGGCAACAACTTTATCTGATGACTCCACGCTTAAATTAACTGTCG
CAAAATGGTTAACACCTAATAGCGAATGGATTCATGAAAAAGGTATTACGCCAGATGTAGTTGTGAACATGCCAGATTAT
GCAACTATGACTATCCCGTCTTCCACCAAAGTCTACAAAAATGGCGATTTCGGTGATGATGTTAAAACCATTGAAACATT
GCTAAAAGCACTAGATTACAATGTTGGGAAAGTAGATGGCTTATACGATACAGACACAGAATATGCTGTTCAAAGATTCC
AAGCAGCAAATAAATTAGATGTGACAGGAATTATGACAGGTGTAACAACCGATAAATTAGTCGAATTAACACAAAAACAT
CTAAAAGAAACAGATCCACAACTACAAAAAGCAAAAGCCTTGGTGAAGTAA

Upstream 100 bases:

>100_bases
AAAAAAAGATACCAAAATGAATGGAAAACTGGTAAAATAAATGAGTTAAATAAAATGTGCTATTACTAGCCACATTTTAC
ATAGAAAGTGGTGAAGAAAG

Downstream 100 bases:

>100_bases
ACGTACGACTTTTTTGAAAAACTGGAGGTAGCGAAAATGGAAACATACTTAGAAATTGAAACATTGATTAAGCGGATTTT
TAATAGTTTTCGTCATGAAG

Product: carboxy-terminal processing proteinase

Products: NA

Alternate protein names: C-terminal processing protease [H]

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MEESPQNEPNNVEKDEEQKAKPGNGYIKMKLFPFIMLLFAFVFVTALVTTIVMSLGDDKQVKVSIPERKEFTKLYDVYDE
ITSKYYKDTKSTTMIDGAINGMVNSLDDPYSTFMSKKESSEFNDTISASFEGIGAEIQEKDGAIVIVSPIKNSPAEKAGL
RPQDIITQVDGKSVKGDTATEATQKIRGEKGTKVTLTIQRSNEDKPFDVTITRDEIPIETVYKEMGSDKIAHVTISTFSE
TTYDELEKALKSLEKDGMKGLVLDLRGNPGGLLDQAVSISSLFVPDGKIVVQEQDKDGDKSAIKADSSSHGDYKVKVPTT
MLIDGGSASASEILAAAAKESGGIKLVGTKSFGKGTVQTATTLSDDSTLKLTVAKWLTPNSEWIHEKGITPDVVVNMPDY
ATMTIPSSTKVYKNGDFGDDVKTIETLLKALDYNVGKVDGLYDTDTEYAVQRFQAANKLDVTGIMTGVTTDKLVELTQKH
LKETDPQLQKAKALVK

Sequences:

>Translated_496_residues
MEESPQNEPNNVEKDEEQKAKPGNGYIKMKLFPFIMLLFAFVFVTALVTTIVMSLGDDKQVKVSIPERKEFTKLYDVYDE
ITSKYYKDTKSTTMIDGAINGMVNSLDDPYSTFMSKKESSEFNDTISASFEGIGAEIQEKDGAIVIVSPIKNSPAEKAGL
RPQDIITQVDGKSVKGDTATEATQKIRGEKGTKVTLTIQRSNEDKPFDVTITRDEIPIETVYKEMGSDKIAHVTISTFSE
TTYDELEKALKSLEKDGMKGLVLDLRGNPGGLLDQAVSISSLFVPDGKIVVQEQDKDGDKSAIKADSSSHGDYKVKVPTT
MLIDGGSASASEILAAAAKESGGIKLVGTKSFGKGTVQTATTLSDDSTLKLTVAKWLTPNSEWIHEKGITPDVVVNMPDY
ATMTIPSSTKVYKNGDFGDDVKTIETLLKALDYNVGKVDGLYDTDTEYAVQRFQAANKLDVTGIMTGVTTDKLVELTQKH
LKETDPQLQKAKALVK
>Mature_496_residues
MEESPQNEPNNVEKDEEQKAKPGNGYIKMKLFPFIMLLFAFVFVTALVTTIVMSLGDDKQVKVSIPERKEFTKLYDVYDE
ITSKYYKDTKSTTMIDGAINGMVNSLDDPYSTFMSKKESSEFNDTISASFEGIGAEIQEKDGAIVIVSPIKNSPAEKAGL
RPQDIITQVDGKSVKGDTATEATQKIRGEKGTKVTLTIQRSNEDKPFDVTITRDEIPIETVYKEMGSDKIAHVTISTFSE
TTYDELEKALKSLEKDGMKGLVLDLRGNPGGLLDQAVSISSLFVPDGKIVVQEQDKDGDKSAIKADSSSHGDYKVKVPTT
MLIDGGSASASEILAAAAKESGGIKLVGTKSFGKGTVQTATTLSDDSTLKLTVAKWLTPNSEWIHEKGITPDVVVNMPDY
ATMTIPSSTKVYKNGDFGDDVKTIETLLKALDYNVGKVDGLYDTDTEYAVQRFQAANKLDVTGIMTGVTTDKLVELTQKH
LKETDPQLQKAKALVK

Specific function: Involved In The Cleavage Of A C-Terminal Peptide Of 11 Residues From The Precursor Form Of Penicillin-Binding Protein 3 (Pbp3). May Be Involved In Protection Of The Bacterium From Thermal And Osmotic Stresses. [C]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Associated With The Periplasmic Protein Side Of The Cytoplasm Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=315, Percent_Identity=35.5555555555556, Blast_Score=145, Evalue=6e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41; PF01471 PG_binding_1 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 54119; Mature: 54119

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEESPQNEPNNVEKDEEQKAKPGNGYIKMKLFPFIMLLFAFVFVTALVTTIVMSLGDDKQ
CCCCCCCCCCCCCCCHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VKVSIPERKEFTKLYDVYDEITSKYYKDTKSTTMIDGAINGMVNSLDDPYSTFMSKKESS
EEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCHHHHHHHHHCCC
EFNDTISASFEGIGAEIQEKDGAIVIVSPIKNSPAEKAGLRPQDIITQVDGKSVKGDTAT
CCCHHHHHHHCCCCCEEECCCCCEEEEECCCCCCHHHHCCCHHHHHHHCCCCCCCCCCHH
EATQKIRGEKGTKVTLTIQRSNEDKPFDVTITRDEIPIETVYKEMGSDKIAHVTISTFSE
HHHHHHCCCCCCEEEEEEEECCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCC
TTYDELEKALKSLEKDGMKGLVLDLRGNPGGLLDQAVSISSLFVPDGKIVVQEQDKDGDK
CCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHEEECCCCEEEEEECCCCCCC
SAIKADSSSHGDYKVKVPTTMLIDGGSASASEILAAAAKESGGIKLVGTKSFGKGTVQTA
HHEECCCCCCCCEEEEECEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCEEEE
TTLSDDSTLKLTVAKWLTPNSEWIHEKGITPDVVVNMPDYATMTIPSSTKVYKNGDFGDD
EEECCCCEEEEEEEECCCCCHHHHHHCCCCCCEEEECCCCEEEECCCCCEEEECCCCCCH
VKTIETLLKALDYNVGKVDGLYDTDTEYAVQRFQAANKLDVTGIMTGVTTDKLVELTQKH
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHH
LKETDPQLQKAKALVK
HHCCCHHHHHHHHHCC
>Mature Secondary Structure
MEESPQNEPNNVEKDEEQKAKPGNGYIKMKLFPFIMLLFAFVFVTALVTTIVMSLGDDKQ
CCCCCCCCCCCCCCCHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VKVSIPERKEFTKLYDVYDEITSKYYKDTKSTTMIDGAINGMVNSLDDPYSTFMSKKESS
EEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCHHHHHHHHHCCC
EFNDTISASFEGIGAEIQEKDGAIVIVSPIKNSPAEKAGLRPQDIITQVDGKSVKGDTAT
CCCHHHHHHHCCCCCEEECCCCCEEEEECCCCCCHHHHCCCHHHHHHHCCCCCCCCCCHH
EATQKIRGEKGTKVTLTIQRSNEDKPFDVTITRDEIPIETVYKEMGSDKIAHVTISTFSE
HHHHHHCCCCCCEEEEEEEECCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCC
TTYDELEKALKSLEKDGMKGLVLDLRGNPGGLLDQAVSISSLFVPDGKIVVQEQDKDGDK
CCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHEEECCCCEEEEEECCCCCCC
SAIKADSSSHGDYKVKVPTTMLIDGGSASASEILAAAAKESGGIKLVGTKSFGKGTVQTA
HHEECCCCCCCCEEEEECEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCEEEE
TTLSDDSTLKLTVAKWLTPNSEWIHEKGITPDVVVNMPDYATMTIPSSTKVYKNGDFGDD
EEECCCCEEEEEEEECCCCCHHHHHHCCCCCCEEEECCCCEEEECCCCCEEEECCCCCCH
VKTIETLLKALDYNVGKVDGLYDTDTEYAVQRFQAANKLDVTGIMTGVTTDKLVELTQKH
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHH
LKETDPQLQKAKALVK
HHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8996100; 9734814; 9384377 [H]