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The map label for this gene is fabD

Identifier: 226224411

GI number: 226224411

Start: 1868382

End: 1869323

Strand: Reverse

Name: fabD

Synonym: Lm4b_01824

Alternate gene names: 226224411

Gene position: 1869323-1868382 (Counterclockwise)

Preceding gene: 226224412

Following gene: 226224410

Centisome position: 64.18

GC content: 40.66

Gene sequence:

>942_bases
ATGACTAAAATTGCATTTGTATTTCCCGGTCAAGGAGCACAAAAAATTGGCATGGGACAAGATGTAGCAGCAGAATATCC
TGAAGCAAAAAAAATCTATGATGATGCTGACGAAAGACTCGGGTTTTCAATCACAGAAATTATTACAGAAGGTCCAATTG
AATTATTAACGAAATCCGAAAACGCACAACCAGCTTTAGTTTCCACAAGTGTTGCTATTTTACGCGCTTTAGAAACATAT
GGTGTGAAAGCTGATTACGTAGCGGGACATAGCCTTGGTGAATATAGTGCGCTTGTTGCTGGCGGATTTTTAGAAGCAAG
TGATGCGATTTACCTTGTACGTAAGCGCGGTGAATTAATGGAAGCAGCTGTACCAAATGGTGCTGGCGCAATGGCTGCAG
TTCTTGGTGTAGACCGGGAAACATTAAAAACAATCACCGAAGAAGTAACTAAAGAAGGCGATGCAGTACAACTTGCTAAC
CTTAACTGCCCAGGACAAATCGTTATTTCTGGAACAACAGCTGGCGTTGAAAAAGCAGGCGAAAAAGCAAAAGAAAGTGG
CGCAAAACGCGTATTACCACTTGCTGTTAGCGGACCTTTCCACTCTAGCTTAATGGAACCAGCCGCACTTGCTTTCCGTG
ATGTTTTAGCAGAGGTTAAAATTTCTGATGGTCAGATTCCAGTGGTTAATAACGTGGACGCTAAAGAAACTACGGATAAA
TCCGAAATTAGCGATAAACTAATCAAGCAAATCTATTCTCCAGTATTATGGGAAGATATCGTCGAAGAATTAATTAAAAA
CGGCGTAGATACGTTTGTCGAAATTGGTTCTGGAAAAGTCTTAGCAGGTTTAATTAAAAAAATTAATCGTGATGTAACTG
TACTGTCAGCAGGTGACGCTGAATCAGTGAAAAGCGTTGCAGCGACATTGAAAGGAGAATAA

Upstream 100 bases:

>100_bases
TTCACCACAATCCGTCAAGTACGTGAAATGGTTGAAAAACAAGTGGTCGAAACAATTAAAGCAGAAGTAGACAAAGTAAA
AGTAGGAGGAACAGAATCTA

Downstream 100 bases:

>100_bases
TTAATGACTTTACAAGGCAAAGTAGCAGTAGTAACAGGTGGATCACGCGGAATTGGTCGTGACATCGCCATCAAATTAGC
CAAAGAAGGCGCAAATATTT

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTKIAFVFPGQGAQKIGMGQDVAAEYPEAKKIYDDADERLGFSITEIITEGPIELLTKSENAQPALVSTSVAILRALETY
GVKADYVAGHSLGEYSALVAGGFLEASDAIYLVRKRGELMEAAVPNGAGAMAAVLGVDRETLKTITEEVTKEGDAVQLAN
LNCPGQIVISGTTAGVEKAGEKAKESGAKRVLPLAVSGPFHSSLMEPAALAFRDVLAEVKISDGQIPVVNNVDAKETTDK
SEISDKLIKQIYSPVLWEDIVEELIKNGVDTFVEIGSGKVLAGLIKKINRDVTVLSAGDAESVKSVAATLKGE

Sequences:

>Translated_313_residues
MTKIAFVFPGQGAQKIGMGQDVAAEYPEAKKIYDDADERLGFSITEIITEGPIELLTKSENAQPALVSTSVAILRALETY
GVKADYVAGHSLGEYSALVAGGFLEASDAIYLVRKRGELMEAAVPNGAGAMAAVLGVDRETLKTITEEVTKEGDAVQLAN
LNCPGQIVISGTTAGVEKAGEKAKESGAKRVLPLAVSGPFHSSLMEPAALAFRDVLAEVKISDGQIPVVNNVDAKETTDK
SEISDKLIKQIYSPVLWEDIVEELIKNGVDTFVEIGSGKVLAGLIKKINRDVTVLSAGDAESVKSVAATLKGE
>Mature_312_residues
TKIAFVFPGQGAQKIGMGQDVAAEYPEAKKIYDDADERLGFSITEIITEGPIELLTKSENAQPALVSTSVAILRALETYG
VKADYVAGHSLGEYSALVAGGFLEASDAIYLVRKRGELMEAAVPNGAGAMAAVLGVDRETLKTITEEVTKEGDAVQLANL
NCPGQIVISGTTAGVEKAGEKAKESGAKRVLPLAVSGPFHSSLMEPAALAFRDVLAEVKISDGQIPVVNNVDAKETTDKS
EISDKLIKQIYSPVLWEDIVEELIKNGVDTFVEIGSGKVLAGLIKKINRDVTVLSAGDAESVKSVAATLKGE

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=302, Percent_Identity=31.4569536423841, Blast_Score=135, Evalue=5e-32,
Organism=Escherichia coli, GI1787334, Length=312, Percent_Identity=45.1923076923077, Blast_Score=244, Evalue=4e-66,
Organism=Caenorhabditis elegans, GI71984332, Length=293, Percent_Identity=31.0580204778157, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17550940, Length=295, Percent_Identity=31.5254237288136, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24665753, Length=302, Percent_Identity=36.7549668874172, Blast_Score=152, Evalue=4e-37,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32948; Mature: 32817

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIAFVFPGQGAQKIGMGQDVAAEYPEAKKIYDDADERLGFSITEIITEGPIELLTKSE
CCEEEEEECCCCCHHCCCCCCHHHCCCCHHHHHCCHHHHCCCHHHHHHHCCCHHHHCCCC
NAQPALVSTSVAILRALETYGVKADYVAGHSLGEYSALVAGGFLEASDAIYLVRKRGELM
CCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHCCCEECCCCEEEEECCCHHH
EAAVPNGAGAMAAVLGVDRETLKTITEEVTKEGDAVQLANLNCPGQIVISGTTAGVEKAG
HHCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCHHHHHHH
EKAKESGAKRVLPLAVSGPFHSSLMEPAALAFRDVLAEVKISDGQIPVVNNVDAKETTDK
HHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHEECCCCEEEECCCCCCCCCCH
SEISDKLIKQIYSPVLWEDIVEELIKNGVDTFVEIGSGKVLAGLIKKINRDVTVLSAGDA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCH
ESVKSVAATLKGE
HHHHHHHHHHCCC
>Mature Secondary Structure 
TKIAFVFPGQGAQKIGMGQDVAAEYPEAKKIYDDADERLGFSITEIITEGPIELLTKSE
CEEEEEECCCCCHHCCCCCCHHHCCCCHHHHHCCHHHHCCCHHHHHHHCCCHHHHCCCC
NAQPALVSTSVAILRALETYGVKADYVAGHSLGEYSALVAGGFLEASDAIYLVRKRGELM
CCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHCCCEECCCCEEEEECCCHHH
EAAVPNGAGAMAAVLGVDRETLKTITEEVTKEGDAVQLANLNCPGQIVISGTTAGVEKAG
HHCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCHHHHHHH
EKAKESGAKRVLPLAVSGPFHSSLMEPAALAFRDVLAEVKISDGQIPVVNNVDAKETTDK
HHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHEECCCCEEEECCCCCCCCCCH
SEISDKLIKQIYSPVLWEDIVEELIKNGVDTFVEIGSGKVLAGLIKKINRDVTVLSAGDA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCH
ESVKSVAATLKGE
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]