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The map label for this gene is infC

Identifier: 226224388

GI number: 226224388

Start: 1845711

End: 1846247

Strand: Reverse

Name: infC

Synonym: Lm4b_01801

Alternate gene names: 226224388

Gene position: 1846247-1845711 (Counterclockwise)

Preceding gene: 226224389

Following gene: 226224387

Centisome position: 63.39

GC content: 41.9

Gene sequence:

>537_bases
ATTAAGTGGAGGTGGCTCACCATTAGCAAAGACATGTTGGTAAACGATGGGATTCGTGCACGTGAAGTAAGATTGATCGA
CCAAGACGGTGAACAATTAGGCGTGAAGAGTAAAATCGATGCGCTTCAAATTGCTGAAAAGGCTAATCTTGATCTAGTGC
TTGTTGCTCCAACAGCGAAACCGCCAGTAGCTCGTATCATGGACTACGGTAAATTCCGTTTTGAACAACAGAAGAAAGAT
AAAGAAGCCCGTAAGAACCAAAAAGTCATCGTGATGAAAGAAGTTCGTTTAAGTCCAACGATTGACGAACATGACTTCGA
TACGAAGCTACGTAATGCACGTAAATTCCTTGAAAAAGGCGATAAAGTAAAATGCTCTATCCGTTTTAAAGGTCGTGCCA
TTACACACAAAGAAATCGGTCAGAAGGTGCTTGACCGTTTTGCAAAAGCGTGCGAAGACCTTTGTACAATTGAGCAAAGA
CCAAAAATGGACGGACGTTCCATGTTCTTAGTCCTAGCACCACTTCATGAAAAGTAA

Upstream 100 bases:

>100_bases
GCGGGATTGCTGAAAAGCAGCCCGTTTTTTTATGGCCTCCGAACGAATGAGTTAGCAGGCCGCAGATTTGAACAGCTATT
TTCTATCTTGTTGTAACAAA

Downstream 100 bases:

>100_bases
AGTTTTGAGGAGGAAAAATTCATGCCAAAAATGAAAACCCACCGCGGTTCCGCTAAACGTTTCAAGAGAACAGGATCTGG
AAAATTAAAACGCAGACACG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MKWRWLTISKDMLVNDGIRAREVRLIDQDGEQLGVKSKIDALQIAEKANLDLVLVAPTAKPPVARIMDYGKFRFEQQKKD
KEARKNQKVIVMKEVRLSPTIDEHDFDTKLRNARKFLEKGDKVKCSIRFKGRAITHKEIGQKVLDRFAKACEDLCTIEQR
PKMDGRSMFLVLAPLHEK

Sequences:

>Translated_178_residues
MKWRWLTISKDMLVNDGIRAREVRLIDQDGEQLGVKSKIDALQIAEKANLDLVLVAPTAKPPVARIMDYGKFRFEQQKKD
KEARKNQKVIVMKEVRLSPTIDEHDFDTKLRNARKFLEKGDKVKCSIRFKGRAITHKEIGQKVLDRFAKACEDLCTIEQR
PKMDGRSMFLVLAPLHEK
>Mature_178_residues
MKWRWLTISKDMLVNDGIRAREVRLIDQDGEQLGVKSKIDALQIAEKANLDLVLVAPTAKPPVARIMDYGKFRFEQQKKD
KEARKNQKVIVMKEVRLSPTIDEHDFDTKLRNARKFLEKGDKVKCSIRFKGRAITHKEIGQKVLDRFAKACEDLCTIEQR
PKMDGRSMFLVLAPLHEK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=162, Percent_Identity=50, Blast_Score=150, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20632; Mature: 20632

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWRWLTISKDMLVNDGIRAREVRLIDQDGEQLGVKSKIDALQIAEKANLDLVLVAPTAK
CCEEEEEECCCHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCC
PPVARIMDYGKFRFEQQKKDKEARKNQKVIVMKEVRLSPTIDEHDFDTKLRNARKFLEKG
CHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCC
DKVKCSIRFKGRAITHKEIGQKVLDRFAKACEDLCTIEQRPKMDGRSMFLVLAPLHEK
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCC
>Mature Secondary Structure
MKWRWLTISKDMLVNDGIRAREVRLIDQDGEQLGVKSKIDALQIAEKANLDLVLVAPTAK
CCEEEEEECCCHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCC
PPVARIMDYGKFRFEQQKKDKEARKNQKVIVMKEVRLSPTIDEHDFDTKLRNARKFLEKG
CHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCC
DKVKCSIRFKGRAITHKEIGQKVLDRFAKACEDLCTIEQRPKMDGRSMFLVLAPLHEK
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]