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The map label for this gene is rnhC

Identifier: 226223828

GI number: 226223828

Start: 1234058

End: 1234984

Strand: Reverse

Name: rnhC

Synonym: Lm4b_01233

Alternate gene names: 226223828

Gene position: 1234984-1234058 (Counterclockwise)

Preceding gene: 226223836

Following gene: 226223819

Centisome position: 42.4

GC content: 40.67

Gene sequence:

>927_bases
ATCGCAAATACAGTTATCTTAGTCGATCAACCAACACTTGAAAAAATGAAACAAACATATCTCCCATTTTCTAATCCAAA
GCTACCACCAGGAGCTGTTTTCGCTGCAAAAAAAACCGGTGTTTCCATCACTGGCTACAAGTCGCGCAAAGTGATGTTCC
AAGGAGTAAACGGAGAAGTAGAAGCAAAAAAATGGGTGGCGACTCTTCCAGAATCAAAAACAAAAGCACCTTCCGTCTCT
AAAGGAATTCTTCCGGCAAACTTCGCATCAAAAAATGTCATTGGTTCAGATGAAGTTGGCACCGGTGATTTTTTTGGACC
GATTACGGTTTGTGCCGCATATGTGGACGCCGAAATGATGCCCCTGTTAAAAGAGCTAGGTGTAAAGGACTCGAAAGCAA
TGAAAGATCCAGAAATTTGTCGTATTGCTGAGAAAATCATGCCACTTGTTCCGCACAGTGTGCTGCTTTGCCCTAATCCT
AAATACAACGAACTCCAAAAAAGAGGCATGAACCAAGGACAAATGAAAGCTTTACTACATAACCGCGCGATTGAAAACGT
CTTGAAAAAGCTCGCACCTGTCAAACCAGAAGCGATTTTAATTGATCAATTTGCTGAAAAAAATACGTATTATCGCTATT
TAGCAAAAGAACCAAGCATTATTCGAGAAGATGTGTTTTTTGCGACAAAAGCAGAAGGATTACATCTCTCCGTCGCTGCT
GCTTCGATTATTGCTCGTTATAAATTTGTGCAAGCTTTTGATGCGATGTCAAAAGAAGTTGGCATCCCACTTCCAAAAGG
CGCAGGACCTCATGTGGATGCTGTTGCAGCGGAAATCATCGAACGATTTGGTCTGGAAACATTAGCGAAATATACAAAAC
AGCATTTCGCTAATACAGAGAAAGCATTAAAAATGGTTAAAAAGTAA

Upstream 100 bases:

>100_bases
CACGAAAAAGCAGGAAAGAAAAGAGTCAACCACCCGTTTAGCCGATATTCAGTCTTTCGTCGTAGTATGTTACAATAGAA
CTTTGAAAGGATGATGCCTT

Downstream 100 bases:

>100_bases
AAAAACATCTCGTCAATAAATGGCGAGATGTTTTTATTTATATAGAAGGAATTTGCCAATCAATTGGTTTTACACCATTT
TGTTCTAAAAATTGATTCGT

Product: ribonuclease HIII

Products: NA

Alternate protein names: RNase HIII [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MANTVILVDQPTLEKMKQTYLPFSNPKLPPGAVFAAKKTGVSITGYKSRKVMFQGVNGEVEAKKWVATLPESKTKAPSVS
KGILPANFASKNVIGSDEVGTGDFFGPITVCAAYVDAEMMPLLKELGVKDSKAMKDPEICRIAEKIMPLVPHSVLLCPNP
KYNELQKRGMNQGQMKALLHNRAIENVLKKLAPVKPEAILIDQFAEKNTYYRYLAKEPSIIREDVFFATKAEGLHLSVAA
ASIIARYKFVQAFDAMSKEVGIPLPKGAGPHVDAVAAEIIERFGLETLAKYTKQHFANTEKALKMVKK

Sequences:

>Translated_308_residues
MANTVILVDQPTLEKMKQTYLPFSNPKLPPGAVFAAKKTGVSITGYKSRKVMFQGVNGEVEAKKWVATLPESKTKAPSVS
KGILPANFASKNVIGSDEVGTGDFFGPITVCAAYVDAEMMPLLKELGVKDSKAMKDPEICRIAEKIMPLVPHSVLLCPNP
KYNELQKRGMNQGQMKALLHNRAIENVLKKLAPVKPEAILIDQFAEKNTYYRYLAKEPSIIREDVFFATKAEGLHLSVAA
ASIIARYKFVQAFDAMSKEVGIPLPKGAGPHVDAVAAEIIERFGLETLAKYTKQHFANTEKALKMVKK
>Mature_307_residues
ANTVILVDQPTLEKMKQTYLPFSNPKLPPGAVFAAKKTGVSITGYKSRKVMFQGVNGEVEAKKWVATLPESKTKAPSVSK
GILPANFASKNVIGSDEVGTGDFFGPITVCAAYVDAEMMPLLKELGVKDSKAMKDPEICRIAEKIMPLVPHSVLLCPNPK
YNELQKRGMNQGQMKALLHNRAIENVLKKLAPVKPEAILIDQFAEKNTYYRYLAKEPSIIREDVFFATKAEGLHLSVAAA
SIIARYKFVQAFDAMSKEVGIPLPKGAGPHVDAVAAEIIERFGLETLAKYTKQHFANTEKALKMVKK

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG1039

COG function: function code L; Ribonuclease HIII

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family. RnhC subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001352
- InterPro:   IPR004641
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01351 RNase_HII [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 33806; Mature: 33675

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTVILVDQPTLEKMKQTYLPFSNPKLPPGAVFAAKKTGVSITGYKSRKVMFQGVNGEV
CCCEEEEECCHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEECCCCCEEEEECCCCCC
EAKKWVATLPESKTKAPSVSKGILPANFASKNVIGSDEVGTGDFFGPITVCAAYVDAEMM
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
PLLKELGVKDSKAMKDPEICRIAEKIMPLVPHSVLLCPNPKYNELQKRGMNQGQMKALLH
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHCCCCHHHHHHHHH
NRAIENVLKKLAPVKPEAILIDQFAEKNTYYRYLAKEPSIIREDVFFATKAEGLHLSVAA
HHHHHHHHHHHCCCCCCEEHHHHHHCCCHHHHHHHCCCCHHHHHHHHEECCCCCEEHHHH
ASIIARYKFVQAFDAMSKEVGIPLPKGAGPHVDAVAAEIIERFGLETLAKYTKQHFANTE
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHCCHH
KALKMVKK
HHHHHHCC
>Mature Secondary Structure 
ANTVILVDQPTLEKMKQTYLPFSNPKLPPGAVFAAKKTGVSITGYKSRKVMFQGVNGEV
CCEEEEECCHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEECCCCCEEEEECCCCCC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HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]