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The map label for this gene is pdtaS [H]

Identifier: 226223774

GI number: 226223774

Start: 1182965

End: 1184422

Strand: Direct

Name: pdtaS [H]

Synonym: Lm4b_01178

Alternate gene names: 226223774

Gene position: 1182965-1184422 (Clockwise)

Preceding gene: 226223773

Following gene: 226223775

Centisome position: 40.61

GC content: 37.31

Gene sequence:

>1458_bases
ATGACTAAAACGATTCGAGAAATGTGCTTACGCTACACAGATTTATCGGAGCACGATATTGAAGAATTAATTCACACAGC
CAAGTCGTTAAGTGTTTCAGCCATGTATCAAGATGTAGATGTATTTATTGATGTATACAATAAGCTAACTAGTGAAGCAC
TTGTTATTCATCATACACCACCAAAAACAACCAAATCACTTTACAAAAACAAAGTAGTCGGAGAAACAGCCCTAAGGTCT
AATGAGCCAGGTGTACTTAGAACATTGGAAACAGGTATGAACTCTAACGATCTACTTGCAAAAACACAAGAAAACGTATT
AATTCGCCAAAAAGTTTATCCGATTCGTAATAAACAGCGAGTTATTGCCGTGCTAATTCTAGAAAATGATATTAGCGCCG
AAATTAAAGCTCATTTTGAAATTGACAATGAAGAAACGGCTTATCGAGATGTTTCTACCACGCTGTCTGCCATGAGTAAA
CTAACGGATTCAATTACTGATCAACTAGATGATGCCATTTTGATTTTTGACCGAAACGGGATTTTGCAGCAAAAGAATTG
CGCTGCGGATCAGTATTACGAAAGACTTGGTTATATGGAAGACATCCAAGGCATGCATTATGATAATTTATCCCTCGACC
AGATGATGTTTGACGCAATCATGTATCAAATTGAAACTGGAAAACAACCGATTCAGTTAAAAAAAGAAGTGGTTATCGCC
GGGAATTACTTTATTATGAAGCAGATTTTTGTAAAAGAAGAAGACGAGCAGGAATGCCGCTTTATTCTCATCTTGCATGA
CATCACGGATATTAAAGTGAAAGAAGCAGAAATTGTTTCTAAATCCGTTGCTATTCGTGAAATTCATCACCGTGTCAAAA
ACAATTTGCAATCTGTTGTTTCCTTATTGCGAATTCAAGGCAGACGTTCTACAAGTGTGGAGGCACAGAAGATTCTAAAT
GAAAGTGTCAGCCGAATCCTTGCCATTGCAGCGACACACGAGCTTTTATCGAAGCAAATGGAAGACGGCATTAACCTTTA
TATGGTCATCGAAACAGTCGCCTACAATATTGAAAGATGTTGTACAGATTGTCCAAAAGTAGCTGTAAGAATGGATATTG
ATAAACGCATTTATTTGGACAGTGACCGAACCGTGGCACTGGCGCTTGTCATGAACGAACTCTTACAAAACTCCTATGAT
CACGCATTTCATCCAAATGAATCAGGCGAAATTTTACTACAAATAAAAGAAGAGAAAAATATTATTCACGCAGAAGTAAC
GGACAACGGTCATGGGTTCAACGTTCGTAAAGTGTCCGAAAAAAGCCTAGGACTTTCCATTGTCAAAAGTTACATTAAAG
ATAAACTTCGAGGCAAAGTAACCATTGAATCGAATGAACACGGAACGAAAACAATGTTTGATTTTAAATACAATTCTATC
CATGCTACAAAGAAGTAG

Upstream 100 bases:

>100_bases
AACAACATCACAGAAGAAGAAGCTTACAATATGATTCGTAACCTGAGCATGGACAAACGCTGTCCGATGATGGAAATCGC
AGAAACGATTGTGATGAGCG

Downstream 100 bases:

>100_bases
CTATGAAAAAGCGATGAAGCTTAAAGCCAAGTAACGATACTGTTATTTGTCTTTAAGCTTTTTCTTTTTGCTAGAAAGGA
GTGAGGGTTTTGACGGAAAC

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MTKTIREMCLRYTDLSEHDIEELIHTAKSLSVSAMYQDVDVFIDVYNKLTSEALVIHHTPPKTTKSLYKNKVVGETALRS
NEPGVLRTLETGMNSNDLLAKTQENVLIRQKVYPIRNKQRVIAVLILENDISAEIKAHFEIDNEETAYRDVSTTLSAMSK
LTDSITDQLDDAILIFDRNGILQQKNCAADQYYERLGYMEDIQGMHYDNLSLDQMMFDAIMYQIETGKQPIQLKKEVVIA
GNYFIMKQIFVKEEDEQECRFILILHDITDIKVKEAEIVSKSVAIREIHHRVKNNLQSVVSLLRIQGRRSTSVEAQKILN
ESVSRILAIAATHELLSKQMEDGINLYMVIETVAYNIERCCTDCPKVAVRMDIDKRIYLDSDRTVALALVMNELLQNSYD
HAFHPNESGEILLQIKEEKNIIHAEVTDNGHGFNVRKVSEKSLGLSIVKSYIKDKLRGKVTIESNEHGTKTMFDFKYNSI
HATKK

Sequences:

>Translated_485_residues
MTKTIREMCLRYTDLSEHDIEELIHTAKSLSVSAMYQDVDVFIDVYNKLTSEALVIHHTPPKTTKSLYKNKVVGETALRS
NEPGVLRTLETGMNSNDLLAKTQENVLIRQKVYPIRNKQRVIAVLILENDISAEIKAHFEIDNEETAYRDVSTTLSAMSK
LTDSITDQLDDAILIFDRNGILQQKNCAADQYYERLGYMEDIQGMHYDNLSLDQMMFDAIMYQIETGKQPIQLKKEVVIA
GNYFIMKQIFVKEEDEQECRFILILHDITDIKVKEAEIVSKSVAIREIHHRVKNNLQSVVSLLRIQGRRSTSVEAQKILN
ESVSRILAIAATHELLSKQMEDGINLYMVIETVAYNIERCCTDCPKVAVRMDIDKRIYLDSDRTVALALVMNELLQNSYD
HAFHPNESGEILLQIKEEKNIIHAEVTDNGHGFNVRKVSEKSLGLSIVKSYIKDKLRGKVTIESNEHGTKTMFDFKYNSI
HATKK
>Mature_484_residues
TKTIREMCLRYTDLSEHDIEELIHTAKSLSVSAMYQDVDVFIDVYNKLTSEALVIHHTPPKTTKSLYKNKVVGETALRSN
EPGVLRTLETGMNSNDLLAKTQENVLIRQKVYPIRNKQRVIAVLILENDISAEIKAHFEIDNEETAYRDVSTTLSAMSKL
TDSITDQLDDAILIFDRNGILQQKNCAADQYYERLGYMEDIQGMHYDNLSLDQMMFDAIMYQIETGKQPIQLKKEVVIAG
NYFIMKQIFVKEEDEQECRFILILHDITDIKVKEAEIVSKSVAIREIHHRVKNNLQSVVSLLRIQGRRSTSVEAQKILNE
SVSRILAIAATHELLSKQMEDGINLYMVIETVAYNIERCCTDCPKVAVRMDIDKRIYLDSDRTVALALVMNELLQNSYDH
AFHPNESGEILLQIKEEKNIIHAEVTDNGHGFNVRKVSEKSLGLSIVKSYIKDKLRGKVTIESNEHGTKTMFDFKYNSIH
ATKK

Specific function: Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR [H]

COG id: COG3920

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR022066
- InterPro:   IPR011495
- InterPro:   IPR005467 [H]

Pfam domain/function: PF12282 H_kinase_N; PF02518 HATPase_c; PF07568 HisKA_2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55523; Mature: 55392

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTIREMCLRYTDLSEHDIEELIHTAKSLSVSAMYQDVDVFIDVYNKLTSEALVIHHTP
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEECCC
PKTTKSLYKNKVVGETALRSNEPGVLRTLETGMNSNDLLAKTQENVLIRQKVYPIRNKQR
CHHHHHHHHHHHHCHHHHCCCCCCEEHHHHCCCCCCCCHHHHHCCEEEHHHCCCCCCCCE
VIAVLILENDISAEIKAHFEIDNEETAYRDVSTTLSAMSKLTDSITDQLDDAILIFDRNG
EEEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
ILQQKNCAADQYYERLGYMEDIQGMHYDNLSLDQMMFDAIMYQIETGKQPIQLKKEVVIA
CCCCCCCCHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEE
GNYFIMKQIFVKEEDEQECRFILILHDITDIKVKEAEIVSKSVAIREIHHRVKNNLQSVV
CCHHEEHHHHHCCCCCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLRIQGRRSTSVEAQKILNESVSRILAIAATHELLSKQMEDGINLYMVIETVAYNIERC
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHH
CTDCPKVAVRMDIDKRIYLDSDRTVALALVMNELLQNSYDHAFHPNESGEILLQIKEEKN
HCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCC
IIHAEVTDNGHGFNVRKVSEKSLGLSIVKSYIKDKLRGKVTIESNEHGTKTMFDFKYNSI
EEEEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEEEECCE
HATKK
ECCCC
>Mature Secondary Structure 
TKTIREMCLRYTDLSEHDIEELIHTAKSLSVSAMYQDVDVFIDVYNKLTSEALVIHHTP
CHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEECCC
PKTTKSLYKNKVVGETALRSNEPGVLRTLETGMNSNDLLAKTQENVLIRQKVYPIRNKQR
CHHHHHHHHHHHHCHHHHCCCCCCEEHHHHCCCCCCCCHHHHHCCEEEHHHCCCCCCCCE
VIAVLILENDISAEIKAHFEIDNEETAYRDVSTTLSAMSKLTDSITDQLDDAILIFDRNG
EEEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
ILQQKNCAADQYYERLGYMEDIQGMHYDNLSLDQMMFDAIMYQIETGKQPIQLKKEVVIA
CCCCCCCCHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEE
GNYFIMKQIFVKEEDEQECRFILILHDITDIKVKEAEIVSKSVAIREIHHRVKNNLQSVV
CCHHEEHHHHHCCCCCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLRIQGRRSTSVEAQKILNESVSRILAIAATHELLSKQMEDGINLYMVIETVAYNIERC
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHH
CTDCPKVAVRMDIDKRIYLDSDRTVALALVMNELLQNSYDHAFHPNESGEILLQIKEEKN
HCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCC
IIHAEVTDNGHGFNVRKVSEKSLGLSIVKSYIKDKLRGKVTIESNEHGTKTMFDFKYNSI
EEEEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEEEECCE
HATKK
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]