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The map label for this gene is lytG [H]

Identifier: 226223690

GI number: 226223690

Start: 1102698

End: 1105022

Strand: Direct

Name: lytG [H]

Synonym: Lm4b_01092

Alternate gene names: 226223690

Gene position: 1102698-1105022 (Clockwise)

Preceding gene: 226223689

Following gene: 226223692

Centisome position: 37.86

GC content: 36.22

Gene sequence:

>2325_bases
ATGATAAATAAAAAGTGGATGAAAATTGTAATGATTCCGATGCTAGTTGTTCCAATGTACGGTTTGACAACTGTTGGCGG
ACAATTACAAGATTCATTAACTGGAGAAAATTCCTTTGTTAAAGAGGTTGAAGCTGCAACGACAGCATCGCAACAAGCAT
TTATCGACAAAATAGCACCTGCTGCCCAGGCATCTCAAGAAAAATATCATCTGTTATCTAGTATAACTTTAGCTCAAGCA
ATTCTAGAATCTGGTTGGGGAAAAAGTGGACTTGCTACACAAGGATATAATTTATTTGGTATAAAAGGGAAATATAATGG
ACAATCAGTTATCATGACAACTTCTGAATATGTGAACGGTGAGTGGATTAAAATTGATGCTGAATTCCGCAAATACCCTA
GCTGGAATGAATCTGTCACTGACCATACTCTTTTATTAGTGAACGGAACTTCTTGGAATAAAGACTTATATAAGAAAGTT
GTCGACGCAACGGATTATAAAGTAGCTGCAATGGAGCTTCAAAAAGCTGGATATGCAACCTCTCCTACATATGGTGCTAG
CTTAATTCAAGTAATTGAGAATTATGATTTAGCCAAATATGATGTTTTATACGACAAAATTCTTACTCAAAAATCCACTT
CCGGAAAAGCAACTGTTACAAGTCCGACTGGAAATGGTGTATGGACTTTACCGTATAAAGTAAAAGGAGTGCAATCTGTT
AGTCCAGCTAGCACATACGCTAACAAGGATATCGATTTAGTATCTGTTGCTACAACAAAGAGAGGTACGTACTATCAATT
TAAATATAATGGTAAAGTAGTTGGTTGGGTAGATGGCAAAGCATTAACTATTTATGATAGTGTCAATTATGATAAAGTAA
ATGTCGGACGTGCTAAAATTACTAGCCCAGTAAGTAACGGTATCTGGTCTAAACCATACAATGTTTATGGAAGAGAATTT
GTTACGAATGCAACAACTTACGCACAACAAGAAATTAAACTTTTACGCGAAGCACAAACTGCTAAAGGTACTTATTACCA
ATTTAGCATAAATAATAAAACTATTGGTTGGATTGATAAACGAGCTCTCACTATCTATCCGTATGATTCCATTATTTCAA
GTAAAAATGTGAACCTTGACGGACAAATTACTAATCCAACCGGAAATGGTATTTGGACTAAAGCGTACAAACTTGAAGGA
ACAACTTCTGTGGCGCAGGCTACGAAATATGCAAATAAAGATGTGAAAATCAGCCAACAAATCGAAACTCAACATGGTAC
TTATTACAATATCAGTATCGATGGGAAAGCAATTGGTTGGTTAGATAGAAACGCTATTACACTGTATGATCAAGAGGAAT
ACAATAAAACAGTTGCTATTGACGCAGTAGTAAAAAATGTGAAGGGTAATGCTGTATGGACAGAACCTTACCGTACAGTT
GGTACAAAATTAATCGGACCAGCGGAAACTTACTTGAATAAAGAAGTGGAAGTCGTCCGTGAAGCAAAAACGCCAAAAGG
AACTTACTACCAATTTAAATCTGGTGGCAAAGTAATCGGCTGGTTAGATAAAAAAGCTTTCGATGTATATGACAATATTA
ATTACAACAAAGCGGTTAATTTAGACGCTGTAGTGGAAAATGTGACAGGTAATGCAGTTTGGACGGCTCCTTATAAGAGT
AAAGGTGTTAAACTTGTTACTTCAGCAGCAACCTATAAAGGCAAGGCAACAAAAATAACTCGTGAAGCGCAAACAAGTAG
AGGAACATATTACGAGTTTAGTGTTGATGGTAAAGTCATTGGCTGGTTAGATAAAAAAGCTTTCGATGTATATGACAATA
TTAATTACAACAAAGCGGTTAACTTAGATGCTGTAGTGGAAAATGTGACAGGCAACGCAGTTTGGACTGCTCCATATAAG
AGTAAGGGTGTTAAATTAGTTACTTCAGCAGCCACATATAAAGATAAAGCAACTAAAATAACTCGAGAAGCGCAAACAAG
TAGAGGAACTTACTACGAATTTAGCGTAAACGGCAAAGTAATCGGTTGGTTAGATAAAAAAGCTTTTGATGTATATGATT
CTATTGAGTACAATAAAGCGATTAATATGACTGGATTACTTAGCAACGCGCCAGGTAATGGCATTTGGACAGAGCCGTAT
AGAGTTATTGGCACAAAAAATGTAGGACAAGCAACTGCTTATGCTAACAAGACAGTACAGTTGATACGCGAGGCTAAGAC
TACACGTGCAACTTACTATCAAATGAGTGTAAATGGTAAAATAGTTGGTTGGGTAGATAAACGAGCTTTTACAAACGTTA
AATAG

Upstream 100 bases:

>100_bases
ATAATACCATTTATTTTTTTTGTAATAAATTTGTAACTTACGGAGGCATAAAGTTTGGTAAAATTAGGACAATAAACAAA
TTAAGGAGTGGTTGGAGAAT

Downstream 100 bases:

>100_bases
ACTAAAAATAATCATATAAAAACAGAGTGAGATTTCTCACTCTGTTTTTATATGATTATAGATTAAGATTTAGTGATGTA
AATAAGTTCCTTCAAGAAGT

Product: autolysin (N-acetylmuramoyl-L-alanine amidase)

Products: NA

Alternate protein names: Autolysin lytG; Exo-beta-N-acetylglucosaminidase lytG; Peptidoglycan hydrolase lytG [H]

Number of amino acids: Translated: 774; Mature: 774

Protein sequence:

>774_residues
MINKKWMKIVMIPMLVVPMYGLTTVGGQLQDSLTGENSFVKEVEAATTASQQAFIDKIAPAAQASQEKYHLLSSITLAQA
ILESGWGKSGLATQGYNLFGIKGKYNGQSVIMTTSEYVNGEWIKIDAEFRKYPSWNESVTDHTLLLVNGTSWNKDLYKKV
VDATDYKVAAMELQKAGYATSPTYGASLIQVIENYDLAKYDVLYDKILTQKSTSGKATVTSPTGNGVWTLPYKVKGVQSV
SPASTYANKDIDLVSVATTKRGTYYQFKYNGKVVGWVDGKALTIYDSVNYDKVNVGRAKITSPVSNGIWSKPYNVYGREF
VTNATTYAQQEIKLLREAQTAKGTYYQFSINNKTIGWIDKRALTIYPYDSIISSKNVNLDGQITNPTGNGIWTKAYKLEG
TTSVAQATKYANKDVKISQQIETQHGTYYNISIDGKAIGWLDRNAITLYDQEEYNKTVAIDAVVKNVKGNAVWTEPYRTV
GTKLIGPAETYLNKEVEVVREAKTPKGTYYQFKSGGKVIGWLDKKAFDVYDNINYNKAVNLDAVVENVTGNAVWTAPYKS
KGVKLVTSAATYKGKATKITREAQTSRGTYYEFSVDGKVIGWLDKKAFDVYDNINYNKAVNLDAVVENVTGNAVWTAPYK
SKGVKLVTSAATYKDKATKITREAQTSRGTYYEFSVNGKVIGWLDKKAFDVYDSIEYNKAINMTGLLSNAPGNGIWTEPY
RVIGTKNVGQATAYANKTVQLIREAKTTRATYYQMSVNGKIVGWVDKRAFTNVK

Sequences:

>Translated_774_residues
MINKKWMKIVMIPMLVVPMYGLTTVGGQLQDSLTGENSFVKEVEAATTASQQAFIDKIAPAAQASQEKYHLLSSITLAQA
ILESGWGKSGLATQGYNLFGIKGKYNGQSVIMTTSEYVNGEWIKIDAEFRKYPSWNESVTDHTLLLVNGTSWNKDLYKKV
VDATDYKVAAMELQKAGYATSPTYGASLIQVIENYDLAKYDVLYDKILTQKSTSGKATVTSPTGNGVWTLPYKVKGVQSV
SPASTYANKDIDLVSVATTKRGTYYQFKYNGKVVGWVDGKALTIYDSVNYDKVNVGRAKITSPVSNGIWSKPYNVYGREF
VTNATTYAQQEIKLLREAQTAKGTYYQFSINNKTIGWIDKRALTIYPYDSIISSKNVNLDGQITNPTGNGIWTKAYKLEG
TTSVAQATKYANKDVKISQQIETQHGTYYNISIDGKAIGWLDRNAITLYDQEEYNKTVAIDAVVKNVKGNAVWTEPYRTV
GTKLIGPAETYLNKEVEVVREAKTPKGTYYQFKSGGKVIGWLDKKAFDVYDNINYNKAVNLDAVVENVTGNAVWTAPYKS
KGVKLVTSAATYKGKATKITREAQTSRGTYYEFSVDGKVIGWLDKKAFDVYDNINYNKAVNLDAVVENVTGNAVWTAPYK
SKGVKLVTSAATYKDKATKITREAQTSRGTYYEFSVNGKVIGWLDKKAFDVYDSIEYNKAINMTGLLSNAPGNGIWTEPY
RVIGTKNVGQATAYANKTVQLIREAKTTRATYYQMSVNGKIVGWVDKRAFTNVK
>Mature_774_residues
MINKKWMKIVMIPMLVVPMYGLTTVGGQLQDSLTGENSFVKEVEAATTASQQAFIDKIAPAAQASQEKYHLLSSITLAQA
ILESGWGKSGLATQGYNLFGIKGKYNGQSVIMTTSEYVNGEWIKIDAEFRKYPSWNESVTDHTLLLVNGTSWNKDLYKKV
VDATDYKVAAMELQKAGYATSPTYGASLIQVIENYDLAKYDVLYDKILTQKSTSGKATVTSPTGNGVWTLPYKVKGVQSV
SPASTYANKDIDLVSVATTKRGTYYQFKYNGKVVGWVDGKALTIYDSVNYDKVNVGRAKITSPVSNGIWSKPYNVYGREF
VTNATTYAQQEIKLLREAQTAKGTYYQFSINNKTIGWIDKRALTIYPYDSIISSKNVNLDGQITNPTGNGIWTKAYKLEG
TTSVAQATKYANKDVKISQQIETQHGTYYNISIDGKAIGWLDRNAITLYDQEEYNKTVAIDAVVKNVKGNAVWTEPYRTV
GTKLIGPAETYLNKEVEVVREAKTPKGTYYQFKSGGKVIGWLDKKAFDVYDNINYNKAVNLDAVVENVTGNAVWTAPYKS
KGVKLVTSAATYKGKATKITREAQTSRGTYYEFSVDGKVIGWLDKKAFDVYDNINYNKAVNLDAVVENVTGNAVWTAPYK
SKGVKLVTSAATYKDKATKITREAQTSRGTYYEFSVNGKVIGWLDKKAFDVYDSIEYNKAINMTGLLSNAPGNGIWTEPY
RVIGTKNVGQATAYANKTVQLIREAKTTRATYYQMSVNGKIVGWVDKRAFTNVK

Specific function: Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Acts processively from the ends of the glycan strands. Also plays a role in motility, chemotaxis and cell division [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 73 family [H]

Homologues:

Organism=Escherichia coli, GI1787321, Length=149, Percent_Identity=36.241610738255, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000423
- InterPro:   IPR013338
- InterPro:   IPR002901 [H]

Pfam domain/function: PF01832 Glucosaminidase [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 85830; Mature: 85830

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINKKWMKIVMIPMLVVPMYGLTTVGGQLQDSLTGENSFVKEVEAATTASQQAFIDKIAP
CCCHHHHHHHHHHHHHHHHHCHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC
AAQASQEKYHLLSSITLAQAILESGWGKSGLATQGYNLFGIKGKYNGQSVIMTTSEYVNG
HHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEHHHCCC
EWIKIDAEFRKYPSWNESVTDHTLLLVNGTSWNKDLYKKVVDATDYKVAAMELQKAGYAT
EEEEEEHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCEEEEEHHHHCCCCC
SPTYGASLIQVIENYDLAKYDVLYDKILTQKSTSGKATVTSPTGNGVWTLPYKVKGVQSV
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEECCEEECCCCCC
SPASTYANKDIDLVSVATTKRGTYYQFKYNGKVVGWVDGKALTIYDSVNYDKVNVGRAKI
CCCHHHCCCCCEEEEEEECCCCEEEEEEECCEEEEEECCCEEEEEECCCCCEEECCCEEE
TSPVSNGIWSKPYNVYGREFVTNATTYAQQEIKLLREAQTAKGTYYQFSINNKTIGWIDK
CCCHHCCCCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEEC
RALTIYPYDSIISSKNVNLDGQITNPTGNGIWTKAYKLEGTTSVAQATKYANKDVKISQQ
CEEEEECCHHHHCCCCCCCCCEEECCCCCCEEEEEEEECCCHHHHHHHHHCCCCCEEEEE
IETQHGTYYNISIDGKAIGWLDRNAITLYDQEEYNKTVAIDAVVKNVKGNAVWTEPYRTV
ECCCCCCEEEEEECCEEEEEECCCEEEEEEHHHCCCEEEEEHHHHCCCCCEEECCCHHHH
GTKLIGPAETYLNKEVEVVREAKTPKGTYYQFKSGGKVIGWLDKKAFDVYDNINYNKAVN
CCCCCCCHHHHHCCHHHHHHHCCCCCCCEEEECCCCEEEEECCCCCEEHHCCCCCCCEEE
LDAVVENVTGNAVWTAPYKSKGVKLVTSAATYKGKATKITREAQTSRGTYYEFSVDGKVI
HHHHHHCCCCCEEEECCCCCCCEEEEEECCCCCCCCEEEEHHHHCCCCCEEEEEECCEEE
GWLDKKAFDVYDNINYNKAVNLDAVVENVTGNAVWTAPYKSKGVKLVTSAATYKDKATKI
EEECCCCEEHHCCCCCCCEEEHHHHHHCCCCCEEEECCCCCCCEEEEEECHHCCHHHHHH
TREAQTSRGTYYEFSVNGKVIGWLDKKAFDVYDSIEYNKAINMTGLLSNAPGNGIWTEPY
HHHHHCCCCCEEEEEECCEEEEEECCCHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCE
RVIGTKNVGQATAYANKTVQLIREAKTTRATYYQMSVNGKIVGWVDKRAFTNVK
EEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCEEEEEECCCCCCCCC
>Mature Secondary Structure
MINKKWMKIVMIPMLVVPMYGLTTVGGQLQDSLTGENSFVKEVEAATTASQQAFIDKIAP
CCCHHHHHHHHHHHHHHHHHCHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC
AAQASQEKYHLLSSITLAQAILESGWGKSGLATQGYNLFGIKGKYNGQSVIMTTSEYVNG
HHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEHHHCCC
EWIKIDAEFRKYPSWNESVTDHTLLLVNGTSWNKDLYKKVVDATDYKVAAMELQKAGYAT
EEEEEEHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCEEEEEHHHHCCCCC
SPTYGASLIQVIENYDLAKYDVLYDKILTQKSTSGKATVTSPTGNGVWTLPYKVKGVQSV
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEECCEEECCCCCC
SPASTYANKDIDLVSVATTKRGTYYQFKYNGKVVGWVDGKALTIYDSVNYDKVNVGRAKI
CCCHHHCCCCCEEEEEEECCCCEEEEEEECCEEEEEECCCEEEEEECCCCCEEECCCEEE
TSPVSNGIWSKPYNVYGREFVTNATTYAQQEIKLLREAQTAKGTYYQFSINNKTIGWIDK
CCCHHCCCCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEEC
RALTIYPYDSIISSKNVNLDGQITNPTGNGIWTKAYKLEGTTSVAQATKYANKDVKISQQ
CEEEEECCHHHHCCCCCCCCCEEECCCCCCEEEEEEEECCCHHHHHHHHHCCCCCEEEEE
IETQHGTYYNISIDGKAIGWLDRNAITLYDQEEYNKTVAIDAVVKNVKGNAVWTEPYRTV
ECCCCCCEEEEEECCEEEEEECCCEEEEEEHHHCCCEEEEEHHHHCCCCCEEECCCHHHH
GTKLIGPAETYLNKEVEVVREAKTPKGTYYQFKSGGKVIGWLDKKAFDVYDNINYNKAVN
CCCCCCCHHHHHCCHHHHHHHCCCCCCCEEEECCCCEEEEECCCCCEEHHCCCCCCCEEE
LDAVVENVTGNAVWTAPYKSKGVKLVTSAATYKGKATKITREAQTSRGTYYEFSVDGKVI
HHHHHHCCCCCEEEECCCCCCCEEEEEECCCCCCCCEEEEHHHHCCCCCEEEEEECCEEE
GWLDKKAFDVYDNINYNKAVNLDAVVENVTGNAVWTAPYKSKGVKLVTSAATYKDKATKI
EEECCCCEEHHCCCCCCCEEEHHHHHHCCCCCEEEECCCCCCCEEEEEECHHCCHHHHHH
TREAQTSRGTYYEFSVNGKVIGWLDKKAFDVYDSIEYNKAINMTGLLSNAPGNGIWTEPY
HHHHHCCCCCEEEEEECCEEEEEECCCHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCE
RVIGTKNVGQATAYANKTVQLIREAKTTRATYYQMSVNGKIVGWVDKRAFTNVK
EEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]