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The map label for this gene is pycA

Identifier: 226223686

GI number: 226223686

Start: 1095883

End: 1099323

Strand: Direct

Name: pycA

Synonym: Lm4b_01088

Alternate gene names: 226223686

Gene position: 1095883-1099323 (Clockwise)

Preceding gene: 226223685

Following gene: 226223687

Centisome position: 37.62

GC content: 39.49

Gene sequence:

>3441_bases
ATGAATCGAATTAAAAAAGTATTAGTAGCAAACCGCGGAGAAATTGCTATCCGTGTTATGCGTGCGTGTACTGAACTCAA
AATCAAAACAGTGGCTATTTATTCACAAGAAGATACCGGAAGTTTTCACCGGTATAAATCAGATGAAGCTTATCTGGTTG
GAGCAGGGAAAAAGCCTATTGATGCGTATCTAGATATCGAAAACATAATAGAGATTGCTAAAGAATCTGGTGCAGACGCG
ATTCATCCGGGATATGGTTTCTTGTCCGAAAACATTGAATTTGCTCGTCGTTGTGAGCAAGAAGGCATTATTTTCGTTGG
TCCTAAATCAAAACACCTAGATATGTTTGGTGATAAAATCAAAGCAAAAGAACAAGCTCTATTGGCTGATATTCCAGTAA
TTCCGGGAAGTAATGGACCCGTGGCTGGTATTAAAGAAGTAGAAGAATTTGGTGAGAAAAACGGTTACCCATTAATGATT
AAAGCTTCTCTTGGAGGCGGCGGTCGTGGTATGCGTGTCGTAGAATCAAAAGAACATGTCAAAGAAAGCTTTGAACGTGC
ATCCTCAGAAGCAAAAGCGGCATTTGGGAACGATGAAGTATACGTAGAAAAATGCGTGATGAATCCGAAACATATCGAAG
TACAAATTCTTGGTGACACCCATGGCAACATCGTTCATTTATTTGAACGTGATTGTTCTATCCAACGTCGTCATCAAAAA
GTAGTAGAGGTAGCGCCATGTAATGCGATTACTTCTGAACTACGTAACCGTATCTGTGATGCTGCAGTAAAATTAATGAA
AAATGTTGATTACATTAATGCTGGAACAGTTGAATTTTTAGTGGAAGGCGATGATTTCTACTTTATCGAAGTAAATCCTC
GTGTCCAAGTGGAGCATACAATTACTGAAATGATTACAGGGATTGATATTGTTCAATCACAACTATTCATTGCAGATGGT
TACGCGCTTCACGACCAACTAGTAGCTATTCCTAAGCAAGAGGATATCCATATTCACGGTTCTGCTATTCAAAGCCGTAT
TACAACGGAAGATCCACTTAATAACTTTATGCCAGATACTGGTCGAGTAGATACGTATCGCTCTACAGGTGGGTTTGGAG
TTCGGTTGGATGCTGGTAACGGCTTCCAAGGAACAGTAGTAACACCATTTTATGATTCCTTACTTGTAAAATTATGTACT
TGGGGAATGACATTCGAACAAGCAACGCGCAAAATGCGTCGTAACTTAATTGAATTCCGTATCCGTGGTGTCAAAACGAA
CATTCCTTTCTTATTAAATGTTGTTCGTCATCCGGATTTTGCAAGTGGTAATTATAATACAAGCTTTATTGATACAACAC
CGGAACTATTTAAATTCCCACATATTCGCGACCGTGGTACAAAAACGTTGCGTTATATTGGTAATGTAACGGTTAATGGT
TTCCCAGGAATTAAGCACCGTGATAAACCTGTATATGCAGAACCACGCTTGCCAAAAATTCCGTACGGTTCGCAAATCTC
TCCAGGAACAAAACAAATTTTGGATGCAAAAGGTCCAGAAGGCGTTGTAGACTGGGTGAAAAAACAAGAAGAAGTGCTCT
TAACAGACACTACACTTCGGGATGCGCACCAATCTTTACTTGCAACACGTGTTCGCTCGAAAGACATTTTCCAAATAGCA
GATGCGATGGCTCATTTATTACCAAACATGTTTTCATTTGAAATGTGGGGTGGCGCGACTTTTGACGTGGCATATCGTTT
CCTAAATGAAGATCCTTGGGTGCGCCTAGAGACACTTAGAAAACAAATTCCAAACGTGATGTTCCAAATGTTACTTCGCG
GAGCTAATGCAGTTGGGTATAAAAACTATCCTGACAATGTTATCCGTGAATTCGTTAAGCAATCAGCACAATCCGGTGTG
GATGTATTCCGCGTGTTTGACAGCTTAAACTGGATCAAAGGCATGGAAGTGTCCATTGATGCTGTTCGTGAAGCAGGGAA
GATCGTAGAGGCTGCTATCTGCTATACAGGAGATATCGATGATGACACAAGAACGAAATATACCATAGATTACTATAAAG
ATATGGCGAAAGAGCTCGTTGCTCAAGGCACGCATATCCTAGGAATCAAAGATATGGCTGGGCTTTTAAAACCACAAGCG
GCATACCGTTTGATTGGTGAATTAAAAGATACAGTAGATGTTCCAATCCACCTTCACACGCATGACACAAGCGGTAACGG
TATTTATACTTACGCAGCAGCTGTCAGTGCTGGCGTTGACATTGTGGACGTGGCATCAAGCGCAATGAGTGGGGCTACAA
GCCAACCAAGTATGACTGGTCTTTATTACGGATTAGTGAATGGTAATCGTCAAACGAATTTAGACGCTCAAAATTCCCAA
ATCATTAATCATTACTGGGAAGATGTTCGTCACTATTACAAAGACTTTGACAATGCACTTAATTCACCTCAAACAGAAGT
ATACATTCATGAAATGCCAGGTGGTCAATATACTAACCTTCAACAACAAGCCATTGCAGTTGGACTTGGCGACCGTTGGG
ACGAAGTGAAAGAAATGTATACAGTGGTTAATCAAATGTTTGGTGATATCGTTAAAGTAACACCTTCTTCCAAAGTTGTT
GGAGACTTAGCACTATTTATGGTTCAAAATGAATTATCCGAAGAAGATGTATACGAAAAAGGCGATACCATTGATTTCCC
AGATTCCGTTATCGAATTCTTTATGGGGGAAATTGGTCAACCATACGGCGGCTTCCCAGAAAAACTTCAAAAACTAGTAC
TCAAAGGACGTACACCACTTACAGATCGTCCAGGCGCTTTAATGGAACCAGTTAACTTTGTTGAAGTCAAAGCAGAATTA
AAAGAAAAAATGGGTTATGAACCAACTGAAAAAGATGTCATTTCCTATATTTTGTATCCAAAAGTGTTCCTAGATTATCA
AGAAATGATTAATAAATATGGTGATGTAACAGTCCTTGATACACCAACATTCTATAAAGGAATGCGTTTAGGGGAAACAA
TCGAAGTAGAACTTGAAAAAGGGAAAATCCTTTTAATCAAGCTAAATTCTATTGGTGAACCAATTGCGGATGGCACACGT
GTTATCTATTTTGAATTAAATGGACAACCACGTGAGATTAACATCCAAGATATGAACGTTCAATCCACTGTTATTGCACG
CCGTAAGATTGATACAACTAACCCTGAACATGTTGGAGCTACAATGACAGGTTCAGTCATTCAAGTAGTTGTTAAAAAAG
GCGACTCTGTTAAAAAAGGTGATCCACTACTAATCACAGAAGCAATGAAAATGGAAACAACGATTCAAGCGCCTTTCGAT
GGAGAAGTTAGCAGCATTTATGTTTCTGACGGCGATACTATCGAATCTGGTGATCTTTTAATTGAAGTAAACAGAATTTA
A

Upstream 100 bases:

>100_bases
TAAAAAAAGGGGATTATCATATAAGTGTACATAATCATTTCAACCGTTGGAGGCTATGTATAAAGTATAGAACAGATCAG
TGTTGGTTAGGAGGAAAAAA

Downstream 100 bases:

>100_bases
AAACATAAATGACTAACGGGTGGGAATATGACGCTAATTTAAAGTGAAGAACTTTAAAAATCGATAAGTTAAACGTGAGA
ATAAAGACGTTTTTCCAGAT

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1146; Mature: 1146

Protein sequence:

>1146_residues
MNRIKKVLVANRGEIAIRVMRACTELKIKTVAIYSQEDTGSFHRYKSDEAYLVGAGKKPIDAYLDIENIIEIAKESGADA
IHPGYGFLSENIEFARRCEQEGIIFVGPKSKHLDMFGDKIKAKEQALLADIPVIPGSNGPVAGIKEVEEFGEKNGYPLMI
KASLGGGGRGMRVVESKEHVKESFERASSEAKAAFGNDEVYVEKCVMNPKHIEVQILGDTHGNIVHLFERDCSIQRRHQK
VVEVAPCNAITSELRNRICDAAVKLMKNVDYINAGTVEFLVEGDDFYFIEVNPRVQVEHTITEMITGIDIVQSQLFIADG
YALHDQLVAIPKQEDIHIHGSAIQSRITTEDPLNNFMPDTGRVDTYRSTGGFGVRLDAGNGFQGTVVTPFYDSLLVKLCT
WGMTFEQATRKMRRNLIEFRIRGVKTNIPFLLNVVRHPDFASGNYNTSFIDTTPELFKFPHIRDRGTKTLRYIGNVTVNG
FPGIKHRDKPVYAEPRLPKIPYGSQISPGTKQILDAKGPEGVVDWVKKQEEVLLTDTTLRDAHQSLLATRVRSKDIFQIA
DAMAHLLPNMFSFEMWGGATFDVAYRFLNEDPWVRLETLRKQIPNVMFQMLLRGANAVGYKNYPDNVIREFVKQSAQSGV
DVFRVFDSLNWIKGMEVSIDAVREAGKIVEAAICYTGDIDDDTRTKYTIDYYKDMAKELVAQGTHILGIKDMAGLLKPQA
AYRLIGELKDTVDVPIHLHTHDTSGNGIYTYAAAVSAGVDIVDVASSAMSGATSQPSMTGLYYGLVNGNRQTNLDAQNSQ
IINHYWEDVRHYYKDFDNALNSPQTEVYIHEMPGGQYTNLQQQAIAVGLGDRWDEVKEMYTVVNQMFGDIVKVTPSSKVV
GDLALFMVQNELSEEDVYEKGDTIDFPDSVIEFFMGEIGQPYGGFPEKLQKLVLKGRTPLTDRPGALMEPVNFVEVKAEL
KEKMGYEPTEKDVISYILYPKVFLDYQEMINKYGDVTVLDTPTFYKGMRLGETIEVELEKGKILLIKLNSIGEPIADGTR
VIYFELNGQPREINIQDMNVQSTVIARRKIDTTNPEHVGATMTGSVIQVVVKKGDSVKKGDPLLITEAMKMETTIQAPFD
GEVSSIYVSDGDTIESGDLLIEVNRI

Sequences:

>Translated_1146_residues
MNRIKKVLVANRGEIAIRVMRACTELKIKTVAIYSQEDTGSFHRYKSDEAYLVGAGKKPIDAYLDIENIIEIAKESGADA
IHPGYGFLSENIEFARRCEQEGIIFVGPKSKHLDMFGDKIKAKEQALLADIPVIPGSNGPVAGIKEVEEFGEKNGYPLMI
KASLGGGGRGMRVVESKEHVKESFERASSEAKAAFGNDEVYVEKCVMNPKHIEVQILGDTHGNIVHLFERDCSIQRRHQK
VVEVAPCNAITSELRNRICDAAVKLMKNVDYINAGTVEFLVEGDDFYFIEVNPRVQVEHTITEMITGIDIVQSQLFIADG
YALHDQLVAIPKQEDIHIHGSAIQSRITTEDPLNNFMPDTGRVDTYRSTGGFGVRLDAGNGFQGTVVTPFYDSLLVKLCT
WGMTFEQATRKMRRNLIEFRIRGVKTNIPFLLNVVRHPDFASGNYNTSFIDTTPELFKFPHIRDRGTKTLRYIGNVTVNG
FPGIKHRDKPVYAEPRLPKIPYGSQISPGTKQILDAKGPEGVVDWVKKQEEVLLTDTTLRDAHQSLLATRVRSKDIFQIA
DAMAHLLPNMFSFEMWGGATFDVAYRFLNEDPWVRLETLRKQIPNVMFQMLLRGANAVGYKNYPDNVIREFVKQSAQSGV
DVFRVFDSLNWIKGMEVSIDAVREAGKIVEAAICYTGDIDDDTRTKYTIDYYKDMAKELVAQGTHILGIKDMAGLLKPQA
AYRLIGELKDTVDVPIHLHTHDTSGNGIYTYAAAVSAGVDIVDVASSAMSGATSQPSMTGLYYGLVNGNRQTNLDAQNSQ
IINHYWEDVRHYYKDFDNALNSPQTEVYIHEMPGGQYTNLQQQAIAVGLGDRWDEVKEMYTVVNQMFGDIVKVTPSSKVV
GDLALFMVQNELSEEDVYEKGDTIDFPDSVIEFFMGEIGQPYGGFPEKLQKLVLKGRTPLTDRPGALMEPVNFVEVKAEL
KEKMGYEPTEKDVISYILYPKVFLDYQEMINKYGDVTVLDTPTFYKGMRLGETIEVELEKGKILLIKLNSIGEPIADGTR
VIYFELNGQPREINIQDMNVQSTVIARRKIDTTNPEHVGATMTGSVIQVVVKKGDSVKKGDPLLITEAMKMETTIQAPFD
GEVSSIYVSDGDTIESGDLLIEVNRI
>Mature_1146_residues
MNRIKKVLVANRGEIAIRVMRACTELKIKTVAIYSQEDTGSFHRYKSDEAYLVGAGKKPIDAYLDIENIIEIAKESGADA
IHPGYGFLSENIEFARRCEQEGIIFVGPKSKHLDMFGDKIKAKEQALLADIPVIPGSNGPVAGIKEVEEFGEKNGYPLMI
KASLGGGGRGMRVVESKEHVKESFERASSEAKAAFGNDEVYVEKCVMNPKHIEVQILGDTHGNIVHLFERDCSIQRRHQK
VVEVAPCNAITSELRNRICDAAVKLMKNVDYINAGTVEFLVEGDDFYFIEVNPRVQVEHTITEMITGIDIVQSQLFIADG
YALHDQLVAIPKQEDIHIHGSAIQSRITTEDPLNNFMPDTGRVDTYRSTGGFGVRLDAGNGFQGTVVTPFYDSLLVKLCT
WGMTFEQATRKMRRNLIEFRIRGVKTNIPFLLNVVRHPDFASGNYNTSFIDTTPELFKFPHIRDRGTKTLRYIGNVTVNG
FPGIKHRDKPVYAEPRLPKIPYGSQISPGTKQILDAKGPEGVVDWVKKQEEVLLTDTTLRDAHQSLLATRVRSKDIFQIA
DAMAHLLPNMFSFEMWGGATFDVAYRFLNEDPWVRLETLRKQIPNVMFQMLLRGANAVGYKNYPDNVIREFVKQSAQSGV
DVFRVFDSLNWIKGMEVSIDAVREAGKIVEAAICYTGDIDDDTRTKYTIDYYKDMAKELVAQGTHILGIKDMAGLLKPQA
AYRLIGELKDTVDVPIHLHTHDTSGNGIYTYAAAVSAGVDIVDVASSAMSGATSQPSMTGLYYGLVNGNRQTNLDAQNSQ
IINHYWEDVRHYYKDFDNALNSPQTEVYIHEMPGGQYTNLQQQAIAVGLGDRWDEVKEMYTVVNQMFGDIVKVTPSSKVV
GDLALFMVQNELSEEDVYEKGDTIDFPDSVIEFFMGEIGQPYGGFPEKLQKLVLKGRTPLTDRPGALMEPVNFVEVKAEL
KEKMGYEPTEKDVISYILYPKVFLDYQEMINKYGDVTVLDTPTFYKGMRLGETIEVELEKGKILLIKLNSIGEPIADGTR
VIYFELNGQPREINIQDMNVQSTVIARRKIDTTNPEHVGATMTGSVIQVVVKKGDSVKKGDPLLITEAMKMETTIQAPFD
GEVSSIYVSDGDTIESGDLLIEVNRI

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1149, Percent_Identity=50.2175805047868, Blast_Score=1119, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1149, Percent_Identity=50.2175805047868, Blast_Score=1119, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1149, Percent_Identity=50.2175805047868, Blast_Score=1119, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=452, Percent_Identity=47.1238938053097, Blast_Score=404, Evalue=1e-112,
Organism=Homo sapiens, GI189095269, Length=457, Percent_Identity=44.6389496717724, Blast_Score=365, Evalue=1e-100,
Organism=Homo sapiens, GI65506442, Length=457, Percent_Identity=44.6389496717724, Blast_Score=365, Evalue=1e-100,
Organism=Homo sapiens, GI295821183, Length=457, Percent_Identity=44.6389496717724, Blast_Score=364, Evalue=1e-100,
Organism=Homo sapiens, GI134142062, Length=516, Percent_Identity=32.5581395348837, Blast_Score=239, Evalue=1e-62,
Organism=Homo sapiens, GI38679971, Length=508, Percent_Identity=32.4803149606299, Blast_Score=234, Evalue=5e-61,
Organism=Homo sapiens, GI38679974, Length=508, Percent_Identity=32.4803149606299, Blast_Score=234, Evalue=5e-61,
Organism=Homo sapiens, GI38679960, Length=508, Percent_Identity=32.4803149606299, Blast_Score=233, Evalue=6e-61,
Organism=Homo sapiens, GI38679977, Length=508, Percent_Identity=32.4803149606299, Blast_Score=233, Evalue=6e-61,
Organism=Homo sapiens, GI38679967, Length=508, Percent_Identity=32.4803149606299, Blast_Score=233, Evalue=6e-61,
Organism=Escherichia coli, GI1789654, Length=449, Percent_Identity=45.2115812917595, Blast_Score=375, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17562816, Length=1143, Percent_Identity=49.7812773403325, Blast_Score=1119, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17567343, Length=461, Percent_Identity=43.6008676789588, Blast_Score=353, Evalue=3e-97,
Organism=Caenorhabditis elegans, GI71987519, Length=495, Percent_Identity=40.6060606060606, Blast_Score=345, Evalue=5e-95,
Organism=Caenorhabditis elegans, GI133931226, Length=493, Percent_Identity=30.6288032454361, Blast_Score=218, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI71997168, Length=440, Percent_Identity=33.8636363636364, Blast_Score=215, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI71997163, Length=440, Percent_Identity=33.8636363636364, Blast_Score=214, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1157, Percent_Identity=50.3025064822818, Blast_Score=1103, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1159, Percent_Identity=49.7842968075928, Blast_Score=1100, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=459, Percent_Identity=35.9477124183007, Blast_Score=288, Evalue=3e-78,
Organism=Saccharomyces cerevisiae, GI6324343, Length=512, Percent_Identity=30.46875, Blast_Score=224, Evalue=5e-59,
Organism=Saccharomyces cerevisiae, GI6323863, Length=471, Percent_Identity=32.2717622080679, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24652212, Length=1144, Percent_Identity=50.0874125874126, Blast_Score=1128, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1144, Percent_Identity=50.0874125874126, Blast_Score=1128, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1144, Percent_Identity=50.0874125874126, Blast_Score=1128, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1144, Percent_Identity=50.0874125874126, Blast_Score=1128, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1144, Percent_Identity=50.0874125874126, Blast_Score=1128, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1162, Percent_Identity=49.4836488812392, Blast_Score=1118, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1162, Percent_Identity=49.4836488812392, Blast_Score=1118, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1162, Percent_Identity=49.4836488812392, Blast_Score=1118, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1162, Percent_Identity=49.4836488812392, Blast_Score=1118, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1162, Percent_Identity=49.4836488812392, Blast_Score=1118, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=463, Percent_Identity=42.7645788336933, Blast_Score=366, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24651759, Length=425, Percent_Identity=42.1176470588235, Blast_Score=327, Evalue=2e-89,
Organism=Drosophila melanogaster, GI161076407, Length=511, Percent_Identity=30.7240704500978, Blast_Score=229, Evalue=9e-60,
Organism=Drosophila melanogaster, GI24586460, Length=511, Percent_Identity=30.7240704500978, Blast_Score=229, Evalue=9e-60,
Organism=Drosophila melanogaster, GI24586458, Length=511, Percent_Identity=30.7240704500978, Blast_Score=229, Evalue=9e-60,
Organism=Drosophila melanogaster, GI161076409, Length=511, Percent_Identity=30.7240704500978, Blast_Score=229, Evalue=1e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 128108; Mature: 128108

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRIKKVLVANRGEIAIRVMRACTELKIKTVAIYSQEDTGSFHRYKSDEAYLVGAGKKPI
CCHHHHHHHCCCCHHHHHHHHHHHHCEEEEEEEEECCCCCCCCEECCCCEEEEECCCCCC
DAYLDIENIIEIAKESGADAIHPGYGFLSENIEFARRCEQEGIIFVGPKSKHLDMFGDKI
HHHCCHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHCCCCEEEECCCCCCHHHHHHHH
KAKEQALLADIPVIPGSNGPVAGIKEVEEFGEKNGYPLMIKASLGGGGRGMRVVESKEHV
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCEEECHHHHH
KESFERASSEAKAAFGNDEVYVEKCVMNPKHIEVQILGDTHGNIVHLFERDCSIQRRHQK
HHHHHHHCHHHHHCCCCCCEEEHHHCCCCCEEEEEEEECCCCCEEEEECCCCHHHHHHHH
VVEVAPCNAITSELRNRICDAAVKLMKNVDYINAGTVEFLVEGDDFYFIEVNPRVQVEHT
HHEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEEECCCEEEHHH
ITEMITGIDIVQSQLFIADGYALHDQLVAIPKQEDIHIHGSAIQSRITTEDPLNNFMPDT
HHHHHHHHHHHHHHEEEECCEEECCCEEECCCCCCEEEEHHHHHHCCCCCCCHHHCCCCC
GRVDTYRSTGGFGVRLDAGNGFQGTVVTPFYDSLLVKLCTWGMTFEQATRKMRRNLIEFR
CCCCCEECCCCEEEEEECCCCCCCCEECHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
IRGVKTNIPFLLNVVRHPDFASGNYNTSFIDTTPELFKFPHIRDRGTKTLRYIGNVTVNG
HCCCCCCCHHHHHHHCCCCCCCCCCCCEEECCCHHHHCCCCCCCCCCCEEEEECCEEECC
FPGIKHRDKPVYAEPRLPKIPYGSQISPGTKQILDAKGPEGVVDWVKKQEEVLLTDTTLR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHCCCCEEEECCHHH
DAHQSLLATRVRSKDIFQIADAMAHLLPNMFSFEMWGGATFDVAYRFLNEDPWVRLETLR
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHEEECCCCCHHHHHHHHHCCCCCCHHHHHH
KQIPNVMFQMLLRGANAVGYKNYPDNVIREFVKQSAQSGVDVFRVFDSLNWIKGMEVSID
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEHH
AVREAGKIVEAAICYTGDIDDDTRTKYTIDYYKDMAKELVAQGTHILGIKDMAGLLKPQA
HHHHHHHHEEEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHCCCEEEEHHHHHHHHCHHH
AYRLIGELKDTVDVPIHLHTHDTSGNGIYTYAAAVSAGVDIVDVASSAMSGATSQPSMTG
HHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEHHHHCCCHHHHHHHHHHCCCCCCCCCCE
LYYGLVNGNRQTNLDAQNSQIINHYWEDVRHYYKDFDNALNSPQTEVYIHEMPGGQYTNL
EEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCH
QQQAIAVGLGDRWDEVKEMYTVVNQMFGDIVKVTPSSKVVGDLALFMVQNELSEEDVYEK
HHHHEEEECCCCHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHCCHHHHHHC
GDTIDFPDSVIEFFMGEIGQPYGGFPEKLQKLVLKGRTPLTDRPGALMEPVNFVEVKAEL
CCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHCCCHHHHHHHHH
KEKMGYEPTEKDVISYILYPKVFLDYQEMINKYGDVTVLDTPTFYKGMRLGETIEVELEK
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHCCCCCCEEEEEEEC
GKILLIKLNSIGEPIADGTRVIYFELNGQPREINIQDMNVQSTVIARRKIDTTNPEHVGA
CCEEEEEECCCCCCCCCCCEEEEEEECCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCC
TMTGSVIQVVVKKGDSVKKGDPLLITEAMKMETTIQAPFDGEVSSIYVSDGDTIESGDLL
CHHHHHHHHHHHCCCCCCCCCCEEEEECHHHCEEEECCCCCCCEEEEECCCCEEECCCEE
IEVNRI
EEEECC
>Mature Secondary Structure
MNRIKKVLVANRGEIAIRVMRACTELKIKTVAIYSQEDTGSFHRYKSDEAYLVGAGKKPI
CCHHHHHHHCCCCHHHHHHHHHHHHCEEEEEEEEECCCCCCCCEECCCCEEEEECCCCCC
DAYLDIENIIEIAKESGADAIHPGYGFLSENIEFARRCEQEGIIFVGPKSKHLDMFGDKI
HHHCCHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHCCCCEEEECCCCCCHHHHHHHH
KAKEQALLADIPVIPGSNGPVAGIKEVEEFGEKNGYPLMIKASLGGGGRGMRVVESKEHV
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCEEECHHHHH
KESFERASSEAKAAFGNDEVYVEKCVMNPKHIEVQILGDTHGNIVHLFERDCSIQRRHQK
HHHHHHHCHHHHHCCCCCCEEEHHHCCCCCEEEEEEEECCCCCEEEEECCCCHHHHHHHH
VVEVAPCNAITSELRNRICDAAVKLMKNVDYINAGTVEFLVEGDDFYFIEVNPRVQVEHT
HHEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEEECCCEEEHHH
ITEMITGIDIVQSQLFIADGYALHDQLVAIPKQEDIHIHGSAIQSRITTEDPLNNFMPDT
HHHHHHHHHHHHHHEEEECCEEECCCEEECCCCCCEEEEHHHHHHCCCCCCCHHHCCCCC
GRVDTYRSTGGFGVRLDAGNGFQGTVVTPFYDSLLVKLCTWGMTFEQATRKMRRNLIEFR
CCCCCEECCCCEEEEEECCCCCCCCEECHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
IRGVKTNIPFLLNVVRHPDFASGNYNTSFIDTTPELFKFPHIRDRGTKTLRYIGNVTVNG
HCCCCCCCHHHHHHHCCCCCCCCCCCCEEECCCHHHHCCCCCCCCCCCEEEEECCEEECC
FPGIKHRDKPVYAEPRLPKIPYGSQISPGTKQILDAKGPEGVVDWVKKQEEVLLTDTTLR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHCCCCEEEECCHHH
DAHQSLLATRVRSKDIFQIADAMAHLLPNMFSFEMWGGATFDVAYRFLNEDPWVRLETLR
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHEEECCCCCHHHHHHHHHCCCCCCHHHHHH
KQIPNVMFQMLLRGANAVGYKNYPDNVIREFVKQSAQSGVDVFRVFDSLNWIKGMEVSID
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEHH
AVREAGKIVEAAICYTGDIDDDTRTKYTIDYYKDMAKELVAQGTHILGIKDMAGLLKPQA
HHHHHHHHEEEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHCCCEEEEHHHHHHHHCHHH
AYRLIGELKDTVDVPIHLHTHDTSGNGIYTYAAAVSAGVDIVDVASSAMSGATSQPSMTG
HHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEHHHHCCCHHHHHHHHHHCCCCCCCCCCE
LYYGLVNGNRQTNLDAQNSQIINHYWEDVRHYYKDFDNALNSPQTEVYIHEMPGGQYTNL
EEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCH
QQQAIAVGLGDRWDEVKEMYTVVNQMFGDIVKVTPSSKVVGDLALFMVQNELSEEDVYEK
HHHHEEEECCCCHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHCCHHHHHHC
GDTIDFPDSVIEFFMGEIGQPYGGFPEKLQKLVLKGRTPLTDRPGALMEPVNFVEVKAEL
CCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHCCCHHHHHHHHH
KEKMGYEPTEKDVISYILYPKVFLDYQEMINKYGDVTVLDTPTFYKGMRLGETIEVELEK
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHCCCCCCEEEEEEEC
GKILLIKLNSIGEPIADGTRVIYFELNGQPREINIQDMNVQSTVIARRKIDTTNPEHVGA
CCEEEEEECCCCCCCCCCCEEEEEEECCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCC
TMTGSVIQVVVKKGDSVKKGDPLLITEAMKMETTIQAPFDGEVSSIYVSDGDTIESGDLL
CHHHHHHHHHHHCCCCCCCCCCEEEEECHHHCEEEECCCCCCCEEEEECCCCEEECCCEE
IEVNRI
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]