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The map label for this gene is moaC

Identifier: 226223664

GI number: 226223664

Start: 1074851

End: 1075333

Strand: Direct

Name: moaC

Synonym: Lm4b_01066

Alternate gene names: 226223664

Gene position: 1074851-1075333 (Clockwise)

Preceding gene: 226223663

Following gene: 226223665

Centisome position: 36.9

GC content: 42.03

Gene sequence:

>483_bases
ATGGAAAAAGATGATTTAACGCATTTTAACGATGAAAAACGCGCAAAAATGGTAGATGTTACGAGCAAATCTGAAACAAA
ACGCCGTGCAATCGCTAGAGCTACGATACATATGAATGAAGAAACCTTAGCGCGTATTCATGCTGGTAAAATTGCTAAAG
GAGATGTTTTGGCCGTTGCGCAAGTTGCTGGAATCATGGCGGCTAAAAAAACAAGCGAACTAATTCCAATGTGCCATCCG
ATTATGACGACAAAAGCTGATATTTCTTTTGAAGATGACGGTAAGACCGCGCTAACTATCACGTCCGAAGTCGTAACCGT
TGGAAAGACGGGCGTCGAAATGGAGGCGCTCACGGCAGTAACCATTGCAGCATTAACCATTTATGACATGTGCAAAGCAA
TGGATAAAGGCATGCGGATTGAAAAAACGTATTTAGTGGAAAAAACAGGTGGAAAAAGCGGGACATTTAAAGCAGAAGCG
TAA

Upstream 100 bases:

>100_bases
TGTGAATATGGAATTTCAACAAGATCAAGACCTTTTACCAGAAGAAATAACCGAAATCGCAGTCATTCCGCCAGTAAGCG
GTGGATAAGGAGGGTAATAG

Downstream 100 bases:

>100_bases
CTATTTTGTAGGATAGGAGTTTTGTTTTATGCAATTATTAAAGGATAAATTTGGGCGGGTACACGATTATATTCGTATTT
CAGTAACAGATCGGTGTAAT

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MEKDDLTHFNDEKRAKMVDVTSKSETKRRAIARATIHMNEETLARIHAGKIAKGDVLAVAQVAGIMAAKKTSELIPMCHP
IMTTKADISFEDDGKTALTITSEVVTVGKTGVEMEALTAVTIAALTIYDMCKAMDKGMRIEKTYLVEKTGGKSGTFKAEA

Sequences:

>Translated_160_residues
MEKDDLTHFNDEKRAKMVDVTSKSETKRRAIARATIHMNEETLARIHAGKIAKGDVLAVAQVAGIMAAKKTSELIPMCHP
IMTTKADISFEDDGKTALTITSEVVTVGKTGVEMEALTAVTIAALTIYDMCKAMDKGMRIEKTYLVEKTGGKSGTFKAEA
>Mature_160_residues
MEKDDLTHFNDEKRAKMVDVTSKSETKRRAIARATIHMNEETLARIHAGKIAKGDVLAVAQVAGIMAAKKTSELIPMCHP
IMTTKADISFEDDGKTALTITSEVVTVGKTGVEMEALTAVTIAALTIYDMCKAMDKGMRIEKTYLVEKTGGKSGTFKAEA

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=156, Percent_Identity=52.5641025641026, Blast_Score=154, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=47.6510067114094, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28574490, Length=148, Percent_Identity=46.6216216216216, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=47.4452554744526, Blast_Score=119, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17337; Mature: 17337

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKDDLTHFNDEKRAKMVDVTSKSETKRRAIARATIHMNEETLARIHAGKIAKGDVLAVA
CCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHEEEECHHHHHHHHCCCCCCCCHHHHH
QVAGIMAAKKTSELIPMCHPIMTTKADISFEDDGKTALTITSEVVTVGKTGVEMEALTAV
HHHHHHHHHHHHHHCCCCCHHCCCCCCCEECCCCCEEEEEEEHEEEECCCCCCHHHHHHH
TIAALTIYDMCKAMDKGMRIEKTYLVEKTGGKSGTFKAEA
HHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCEEECC
>Mature Secondary Structure
MEKDDLTHFNDEKRAKMVDVTSKSETKRRAIARATIHMNEETLARIHAGKIAKGDVLAVA
CCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHEEEECHHHHHHHHCCCCCCCCHHHHH
QVAGIMAAKKTSELIPMCHPIMTTKADISFEDDGKTALTITSEVVTVGKTGVEMEALTAV
HHHHHHHHHHHHHHCCCCCHHCCCCCCCEECCCCCEEEEEEEHEEEECCCCCCHHHHHHH
TIAALTIYDMCKAMDKGMRIEKTYLVEKTGGKSGTFKAEA
HHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]