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The map label for this gene is yfkJ [H]

Identifier: 226223557

GI number: 226223557

Start: 975810

End: 976268

Strand: Reverse

Name: yfkJ [H]

Synonym: Lm4b_00958

Alternate gene names: 226223557

Gene position: 976268-975810 (Counterclockwise)

Preceding gene: 226223558

Following gene: 226223556

Centisome position: 33.52

GC content: 39.22

Gene sequence:

>459_bases
TTGTTAAAAGTAGTTTTTGTCTGTTTAGGGAATATTTGTCGTTCACCAATGGCTGAGGGGTTATTTCGGAAAGAAGTTGC
AGAAGCTGGGTTAACGAATGAAATAAAAATTGATTCTGCTGCAACTGGTACTTGGAATTTAGGGAAACCGCCACACCGCG
GGACGCAAGCAGTGTTGAAAAAGCATGGTGTTGATTATCGAGAGATGCGAGCTCGAAAAATTTCTGATGTTGATTTTAAC
GAAGCTGATTTTATTATCGGGATGGATCAGCAAAATTTAGCAGATTTAAATGCACTTAATAATAATCCAGATGTCATCGT
TCGCTCGCTTATGTCCTTTGTGCCTGGTCAAGAGGATAAAGATATTCCAGACCCATATTATACAGGGGATTTTGATGAAA
CCGAACGCATGGTAACTGAGGGAGTAAAGGCCCTTTTAGCTTATATCACAAAAAAATAG

Upstream 100 bases:

>100_bases
ACTTGTGGAGCAAATTTTCGTCCGACTGGAAGCATGTGATGGGATAAATAAAGCGGCTCTGGCCGAATTATATAAGGAAT
GGAAATAAGGAGGAATTCAA

Downstream 100 bases:

>100_bases
TCTGTTTTTAGCCCTAATATGTTTAAAGACTGACCTCACGGGAATATATAAGAGTACAATCAAAAGTGCAGAAAGAGGTT
TTTATACATGTTAGGAATTA

Product: protein-tyrosine-phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MLKVVFVCLGNICRSPMAEGLFRKEVAEAGLTNEIKIDSAATGTWNLGKPPHRGTQAVLKKHGVDYREMRARKISDVDFN
EADFIIGMDQQNLADLNALNNNPDVIVRSLMSFVPGQEDKDIPDPYYTGDFDETERMVTEGVKALLAYITKK

Sequences:

>Translated_152_residues
MLKVVFVCLGNICRSPMAEGLFRKEVAEAGLTNEIKIDSAATGTWNLGKPPHRGTQAVLKKHGVDYREMRARKISDVDFN
EADFIIGMDQQNLADLNALNNNPDVIVRSLMSFVPGQEDKDIPDPYYTGDFDETERMVTEGVKALLAYITKK
>Mature_152_residues
MLKVVFVCLGNICRSPMAEGLFRKEVAEAGLTNEIKIDSAATGTWNLGKPPHRGTQAVLKKHGVDYREMRARKISDVDFN
EADFIIGMDQQNLADLNALNNNPDVIVRSLMSFVPGQEDKDIPDPYYTGDFDETERMVTEGVKALLAYITKK

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=151, Percent_Identity=39.7350993377483, Blast_Score=109, Evalue=1e-24,
Organism=Homo sapiens, GI6005988, Length=151, Percent_Identity=39.0728476821192, Blast_Score=105, Evalue=1e-23,
Organism=Homo sapiens, GI96304457, Length=77, Percent_Identity=42.8571428571429, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6325330, Length=151, Percent_Identity=35.0993377483444, Blast_Score=93, Evalue=2e-20,
Organism=Drosophila melanogaster, GI78711846, Length=154, Percent_Identity=35.0649350649351, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI78706770, Length=149, Percent_Identity=34.8993288590604, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI78706772, Length=149, Percent_Identity=34.8993288590604, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI78706766, Length=151, Percent_Identity=32.4503311258278, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI78706768, Length=151, Percent_Identity=32.4503311258278, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI78706764, Length=130, Percent_Identity=35.3846153846154, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16965; Mature: 16965

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKVVFVCLGNICRSPMAEGLFRKEVAEAGLTNEIKIDSAATGTWNLGKPPHRGTQAVLK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHH
KHGVDYREMRARKISDVDFNEADFIIGMDQQNLADLNALNNNPDVIVRSLMSFVPGQEDK
HHCCCHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
DIPDPYYTGDFDETERMVTEGVKALLAYITKK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKVVFVCLGNICRSPMAEGLFRKEVAEAGLTNEIKIDSAATGTWNLGKPPHRGTQAVLK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHH
KHGVDYREMRARKISDVDFNEADFIIGMDQQNLADLNALNNNPDVIVRSLMSFVPGQEDK
HHCCCHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
DIPDPYYTGDFDETERMVTEGVKALLAYITKK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]