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The map label for this gene is malL [H]

Identifier: 226223480

GI number: 226223480

Start: 900667

End: 902199

Strand: Direct

Name: malL [H]

Synonym: Lm4b_00878

Alternate gene names: 226223480

Gene position: 900667-902199 (Clockwise)

Preceding gene: 226223479

Following gene: 226223481

Centisome position: 30.92

GC content: 40.05

Gene sequence:

>1533_bases
TTGGAATTTTGGCGTCGTAGTGTGTTTTATGAAATTTATATGAAATCATTTCAAGATAGTAATGGCGATGGTTTAGGTGA
TTTTAAAGGTTTAACGAGCAGATTAGATTATCTAGTGGATTTGGGAATTGATGGTATTTGGTTGACTCCATTTTATCCTT
CACCGCAAGTGGATAATGGTTATGATGTGTCTGATTACTGCGATATTAACCCGGATTACGGCGATATGACTGATTTTCGA
GCGTTTATGAAAGCGGCAGATGCTCGAGGAATAAAAGTTATTATCGACTTAGTATTAAATCATTCGTCAACAGAGCATGC
TTGGTTTAAGGAGTCGCGTAGTAGTAAGACGAATCCTAAACGAGATTATTATATTTGGCGAGAAAAACCAAATAATTGGG
AATCGTTTTTTGGTGGTTCTGCTTGGGAAATGGATGAACTTACTGGCGAGTATTACTATCATAGTTTTGCAAAAGAACAG
GCTGACTTAAACTGGGCGAATGAAGCTGTTCGCGCAGAAATGGAGCAAGTTTTAGTGTTTTGGTTGAATGAGGGAGTGGC
GGGATTCAGGTTAGATGTTATCAATAATTTAACGCTCGTACTTGAATTTACGGATAATCCAGTCACATCTGGTGAAATGG
AGCATGTGTATGACCGTAATCAGAGTGGCTTAGAACAAGCGTTAGAGGATATCGCTTCCTTTTGTCGAAAAGAGCGCGAC
GTGTTTCTAGTAGGCGAAATTAGCTCGGACCAATTAGCTGAAATTGCTAGATATAGCTCGAAAAAAATGCTAGATGTCAC
ATTTAATTTTAATTTTGGCAGTGTTGATCAGCTAGATGCAAAATCTGTATTTACGACATTGAATGAGATGGAAACGGCAT
TAAATGAAGGGCAGTGGCCGACGCTTTTCTTTGGAAGTCATGATATGAGCAGGTTCAGAAGTCGCCTCGCATCTGGAGAC
ATAGTAAAGACCCAGTTGCTCGCATTTTTAATGTTAACTGCGAAAGGCGTGCCGTTTATATACTACGGAGAAGAGGTGGG
TATGCCTGATTTAACGTTTTCTTCCGTAAAAGAGATGCGCGATATTCAAGGGACAGCCGCGTACTATCAAGCTTTACAAA
CTGGTTCAGATGAAAAACAAGCACTCGAAATTGCTATTGAAAAAACGCGTGACAAAGCACGTGGGCCGATGATTTTCCCA
GATGGAAAGCCATTTACTCTAGGTGAATCATGGATTAAAATGGCGACTTTGCCGGAAAAAGAAGCACGAACGATGTGGCG
ATTTTATCAAGGATTACTCGCATTTCGTAAAGAAAATGATTTTAAAGAGATGGAATATACTTTTTTGAAGTTGGATGGAG
AAGTACTCAGTTATCAGCGAGGCGAATTTATCTTTTTACTTCATTTTGGTGAGGAAGAGGTAACTTATCCGCTTCAGGGG
AACTATCAGCTTGTTTTTGGAGAAGCAGTGATGGTAGGAAATGGCATTAGAATGGGTGCGCATACTGGAATTGCGCTTAG
AGTGGAGGAATAG

Upstream 100 bases:

>100_bases
TGTGTTACTAACACTTCCACTTATTATCTTGTTCTTATTCTTCTCGAAGAAATTCCAAGAAGGAATGCAATTTACTTTGA
AATAAAAGGAGCGACTGAAC

Downstream 100 bases:

>100_bases
AATGAATACAATCGAAAATTTGTTGCAAGTTTACCGGGAAAATAGTGCTGCGTTTGGGACACGTATCACGTTAAATGGTG
CTGGCGACAAAGATGTATAC

Product: oligo-1,6-glucosidase

Products: NA

Alternate protein names: Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase [H]

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MEFWRRSVFYEIYMKSFQDSNGDGLGDFKGLTSRLDYLVDLGIDGIWLTPFYPSPQVDNGYDVSDYCDINPDYGDMTDFR
AFMKAADARGIKVIIDLVLNHSSTEHAWFKESRSSKTNPKRDYYIWREKPNNWESFFGGSAWEMDELTGEYYYHSFAKEQ
ADLNWANEAVRAEMEQVLVFWLNEGVAGFRLDVINNLTLVLEFTDNPVTSGEMEHVYDRNQSGLEQALEDIASFCRKERD
VFLVGEISSDQLAEIARYSSKKMLDVTFNFNFGSVDQLDAKSVFTTLNEMETALNEGQWPTLFFGSHDMSRFRSRLASGD
IVKTQLLAFLMLTAKGVPFIYYGEEVGMPDLTFSSVKEMRDIQGTAAYYQALQTGSDEKQALEIAIEKTRDKARGPMIFP
DGKPFTLGESWIKMATLPEKEARTMWRFYQGLLAFRKENDFKEMEYTFLKLDGEVLSYQRGEFIFLLHFGEEEVTYPLQG
NYQLVFGEAVMVGNGIRMGAHTGIALRVEE

Sequences:

>Translated_510_residues
MEFWRRSVFYEIYMKSFQDSNGDGLGDFKGLTSRLDYLVDLGIDGIWLTPFYPSPQVDNGYDVSDYCDINPDYGDMTDFR
AFMKAADARGIKVIIDLVLNHSSTEHAWFKESRSSKTNPKRDYYIWREKPNNWESFFGGSAWEMDELTGEYYYHSFAKEQ
ADLNWANEAVRAEMEQVLVFWLNEGVAGFRLDVINNLTLVLEFTDNPVTSGEMEHVYDRNQSGLEQALEDIASFCRKERD
VFLVGEISSDQLAEIARYSSKKMLDVTFNFNFGSVDQLDAKSVFTTLNEMETALNEGQWPTLFFGSHDMSRFRSRLASGD
IVKTQLLAFLMLTAKGVPFIYYGEEVGMPDLTFSSVKEMRDIQGTAAYYQALQTGSDEKQALEIAIEKTRDKARGPMIFP
DGKPFTLGESWIKMATLPEKEARTMWRFYQGLLAFRKENDFKEMEYTFLKLDGEVLSYQRGEFIFLLHFGEEEVTYPLQG
NYQLVFGEAVMVGNGIRMGAHTGIALRVEE
>Mature_510_residues
MEFWRRSVFYEIYMKSFQDSNGDGLGDFKGLTSRLDYLVDLGIDGIWLTPFYPSPQVDNGYDVSDYCDINPDYGDMTDFR
AFMKAADARGIKVIIDLVLNHSSTEHAWFKESRSSKTNPKRDYYIWREKPNNWESFFGGSAWEMDELTGEYYYHSFAKEQ
ADLNWANEAVRAEMEQVLVFWLNEGVAGFRLDVINNLTLVLEFTDNPVTSGEMEHVYDRNQSGLEQALEDIASFCRKERD
VFLVGEISSDQLAEIARYSSKKMLDVTFNFNFGSVDQLDAKSVFTTLNEMETALNEGQWPTLFFGSHDMSRFRSRLASGD
IVKTQLLAFLMLTAKGVPFIYYGEEVGMPDLTFSSVKEMRDIQGTAAYYQALQTGSDEKQALEIAIEKTRDKARGPMIFP
DGKPFTLGESWIKMATLPEKEARTMWRFYQGLLAFRKENDFKEMEYTFLKLDGEVLSYQRGEFIFLLHFGEEEVTYPLQG
NYQLVFGEAVMVGNGIRMGAHTGIALRVEE

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=395, Percent_Identity=33.4177215189873, Blast_Score=228, Evalue=8e-60,
Organism=Escherichia coli, GI1790687, Length=541, Percent_Identity=35.8595194085028, Blast_Score=322, Evalue=5e-89,
Organism=Escherichia coli, GI1786604, Length=345, Percent_Identity=26.3768115942029, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI25147709, Length=382, Percent_Identity=29.0575916230367, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI32565753, Length=375, Percent_Identity=23.7333333333333, Blast_Score=101, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6322245, Length=514, Percent_Identity=33.4630350194552, Blast_Score=278, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6321726, Length=555, Percent_Identity=32.2522522522522, Blast_Score=266, Evalue=6e-72,
Organism=Saccharomyces cerevisiae, GI6319776, Length=545, Percent_Identity=33.2110091743119, Blast_Score=263, Evalue=5e-71,
Organism=Saccharomyces cerevisiae, GI6321731, Length=545, Percent_Identity=33.0275229357798, Blast_Score=263, Evalue=7e-71,
Organism=Saccharomyces cerevisiae, GI6322241, Length=555, Percent_Identity=31.8918918918919, Blast_Score=258, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6322021, Length=555, Percent_Identity=31.8918918918919, Blast_Score=258, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6324416, Length=555, Percent_Identity=31.8918918918919, Blast_Score=257, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24583747, Length=503, Percent_Identity=33.2007952286282, Blast_Score=248, Evalue=9e-66,
Organism=Drosophila melanogaster, GI24583745, Length=500, Percent_Identity=32.8, Blast_Score=248, Evalue=1e-65,
Organism=Drosophila melanogaster, GI24583749, Length=503, Percent_Identity=33.2007952286282, Blast_Score=247, Evalue=1e-65,
Organism=Drosophila melanogaster, GI45549022, Length=538, Percent_Identity=31.9702602230483, Blast_Score=244, Evalue=1e-64,
Organism=Drosophila melanogaster, GI221330053, Length=439, Percent_Identity=35.0797266514806, Blast_Score=239, Evalue=5e-63,
Organism=Drosophila melanogaster, GI24586599, Length=521, Percent_Identity=32.4376199616123, Blast_Score=235, Evalue=5e-62,
Organism=Drosophila melanogaster, GI24586597, Length=530, Percent_Identity=33.3962264150943, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24586591, Length=570, Percent_Identity=30.1754385964912, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24586593, Length=387, Percent_Identity=33.5917312661499, Blast_Score=222, Evalue=6e-58,
Organism=Drosophila melanogaster, GI24586589, Length=501, Percent_Identity=31.1377245508982, Blast_Score=211, Evalue=7e-55,
Organism=Drosophila melanogaster, GI24586587, Length=388, Percent_Identity=32.9896907216495, Blast_Score=209, Evalue=5e-54,
Organism=Drosophila melanogaster, GI281360393, Length=331, Percent_Identity=31.1178247734139, Blast_Score=156, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 58598; Mature: 58598

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFWRRSVFYEIYMKSFQDSNGDGLGDFKGLTSRLDYLVDLGIDGIWLTPFYPSPQVDNG
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCC
YDVSDYCDINPDYGDMTDFRAFMKAADARGIKVIIDLVLNHSSTEHAWFKESRSSKTNPK
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEHHHCCCCCCHHHHHHHCCCCCCCC
RDYYIWREKPNNWESFFGGSAWEMDELTGEYYYHSFAKEQADLNWANEAVRAEMEQVLVF
CCEEEEECCCCCHHHHCCCCCCCHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
WLNEGVAGFRLDVINNLTLVLEFTDNPVTSGEMEHVYDRNQSGLEQALEDIASFCRKERD
HHCCCCCEEEEEEECCEEEEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCC
VFLVGEISSDQLAEIARYSSKKMLDVTFNFNFGSVDQLDAKSVFTTLNEMETALNEGQWP
EEEEEECCHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
TLFFGSHDMSRFRSRLASGDIVKTQLLAFLMLTAKGVPFIYYGEEVGMPDLTFSSVKEMR
EEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHH
DIQGTAAYYQALQTGSDEKQALEIAIEKTRDKARGPMIFPDGKPFTLGESWIKMATLPEK
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHCCCCH
EARTMWRFYQGLLAFRKENDFKEMEYTFLKLDGEVLSYQRGEFIFLLHFGEEEVTYPLQG
HHHHHHHHHHHHHHHHCCCCHHHHEEEEEEECCHHCCCCCCCEEEEEEECCCCEEEECCC
NYQLVFGEAVMVGNGIRMGAHTGIALRVEE
CEEEEEECEEEECCCEEECCCCCEEEEECC
>Mature Secondary Structure
MEFWRRSVFYEIYMKSFQDSNGDGLGDFKGLTSRLDYLVDLGIDGIWLTPFYPSPQVDNG
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCC
YDVSDYCDINPDYGDMTDFRAFMKAADARGIKVIIDLVLNHSSTEHAWFKESRSSKTNPK
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEHHHCCCCCCHHHHHHHCCCCCCCC
RDYYIWREKPNNWESFFGGSAWEMDELTGEYYYHSFAKEQADLNWANEAVRAEMEQVLVF
CCEEEEECCCCCHHHHCCCCCCCHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
WLNEGVAGFRLDVINNLTLVLEFTDNPVTSGEMEHVYDRNQSGLEQALEDIASFCRKERD
HHCCCCCEEEEEEECCEEEEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCC
VFLVGEISSDQLAEIARYSSKKMLDVTFNFNFGSVDQLDAKSVFTTLNEMETALNEGQWP
EEEEEECCHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
TLFFGSHDMSRFRSRLASGDIVKTQLLAFLMLTAKGVPFIYYGEEVGMPDLTFSSVKEMR
EEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHH
DIQGTAAYYQALQTGSDEKQALEIAIEKTRDKARGPMIFPDGKPFTLGESWIKMATLPEK
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHCCCCH
EARTMWRFYQGLLAFRKENDFKEMEYTFLKLDGEVLSYQRGEFIFLLHFGEEEVTYPLQG
HHHHHHHHHHHHHHHHCCCCHHHHEEEEEEECCHHCCCCCCCEEEEEEECCCCEEEECCC
NYQLVFGEAVMVGNGIRMGAHTGIALRVEE
CEEEEEECEEEECCCEEECCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1761534 [H]