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The map label for this gene is inlI [H]

Identifier: 226223239

GI number: 226223239

Start: 653505

End: 655274

Strand: Reverse

Name: inlI [H]

Synonym: Lm4b_00636

Alternate gene names: 226223239

Gene position: 655274-653505 (Counterclockwise)

Preceding gene: 226223240

Following gene: 226223234

Centisome position: 22.5

GC content: 36.95

Gene sequence:

>1770_bases
ATGAGAAAAATGGGAGTCAAAATTGGCTTGTGCGTCCTTTTAATGATGCCATTTACTATATCATTTTCCGCGAATGTCTC
AGCGGAAGAAGAAATTAGTGTAAAAGCCGCTCAAGATGTTGTCAACATTCCTGACCCAGTTTTGAAAAGTTATTTAAATG
GACTCTTAGGACAATCAAGCACAAGTGATATTACTGAAGCTCAGATGGATACTATTACAAATGTCACTATTAGTAACAGT
AGTTTAACTGATTTAACAGGTCTTGATTATGCACATAATTTAACAATTTTACATTTGTCTAATACAGGGGTAACAGATTA
TGCCTTAGTCGCAAAAATACCTAGCCTAACTAATCTTAGCATTGCCGGAGATAACTTAACAAATGATTCATTACCCGATT
TGAATAATTTATCAAACATCACCAACTTAAATCTAAGTCCTGGTAAGCTCGACAATAATGCACTAACTAAATTTAATAAA
ATGTCCAAGTTAAGTTACTTAAATTTAGACAGTAATCCTTCTATTACTAACATCATGCCACTAAAATCCATTCCAAATTT
AGCTACTTTATTTGTCCAGTTTTGTGGAATTAATGATTTCCGTGGAATTGATACTTTTCCTAAATTAGTGAGTTTATCGG
CTTACGGACAAAACGTAGGTAGAACCGTTTTAATCAACAGCTCTATCAAAAGCTCTGCATTGAATTTTGATGAAGCAAAC
CAAACTATCTTTGTGCCGTTTACTTTAATGACTGAACGAGGAGTAAACTTTGATGGCTATTTGTTCCCTTTTACAACTAA
TACAAGTTCTGCTAGCACGTATTTCACTTTAAATGAGACCAAAATTGACGGTAGCCGTTTAACCATTGACGATAAAGGAA
TTACGGTAAGTGGAATTACCAAAAGTTATTTTGATACGATTACTAAAATGGAATACAATGCATTATACAATAACCCCGCC
GGATCGTATCAAACTCCGCCAAATTTCAATAATTATTCCGTATCAGGGGGAAGCTACGACCACTATTTTGACATCGATCA
TTCACTAACCATTACAAATGATTCAGCAATAAGTTATGGGGAACAAACCACTGTTACAGAAGAACAATTTTTAAAAGATG
TTCATGCTGAGACAGATGATGGAACGCCTGTTACTAGTGATTTTAATACGGTTGTAGACTTTAGTAAACCCGGTGTCTAC
ACGGTGACATTAAATGCCGAAAATGCTGCTGGTTTAAAAGCAACGCCAACACAAGTAACGGTGACCATACTTGCAAAACC
AGTCATAACAGCAGATAAGAGCATTTCTTACACGAAAGATTCAACCAAGACAGACCAGCAATTTTTACAAGATATTTCAG
CAAAAACAAGTGATGGTAGTAAGGTAACGAGTGATTTTGATAGCGTTGTTGATTTAGCCAAAGTCGGAACGTATAAAGTG
ACTTTAAATGCGGTAAGTGCAGATGGACTAAATGCTGACCCAGTTATTGTTTTAGTAAATGTGGTAGAGGGAAATGAACC
TCCGACACCACCTGCTCCCGGCCCTGATCCCACACCAGATCCTACGCCAAATCCTAATAATCCAAATATCAATCCCAACC
CAGATAATGGACAATCTGCGAACTCTGAAAACGCATCAAATCCGTCTAACTCAGAAGTAAATGCCGCTTTACCAAACACT
GGCGACGCGAGTCAAGCAACTACTGTGTTAATTGGGATTATCATTGCCGGAGTAGCTATCCTCTTCTTCCGTCAAAGAAA
ACATAGCTAA

Upstream 100 bases:

>100_bases
ACTTTTGATACTATTTTGTTTAACATATTACTAAAAGAGGAATTGTTTTAAGAATACATACGATTATACCGAACAAAAGT
TATTAAAGGAGGAAAAATTC

Downstream 100 bases:

>100_bases
ATAAAAAAGTCGTGACTAGAATTTTAGTCGCGACTTCTTTTTTATTTAGTTACTATACCGTGAAAGGCTCCCATACCTCC
CATTACATTCGTTACGTCAA

Product: internalin protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 589; Mature: 589

Protein sequence:

>589_residues
MRKMGVKIGLCVLLMMPFTISFSANVSAEEEISVKAAQDVVNIPDPVLKSYLNGLLGQSSTSDITEAQMDTITNVTISNS
SLTDLTGLDYAHNLTILHLSNTGVTDYALVAKIPSLTNLSIAGDNLTNDSLPDLNNLSNITNLNLSPGKLDNNALTKFNK
MSKLSYLNLDSNPSITNIMPLKSIPNLATLFVQFCGINDFRGIDTFPKLVSLSAYGQNVGRTVLINSSIKSSALNFDEAN
QTIFVPFTLMTERGVNFDGYLFPFTTNTSSASTYFTLNETKIDGSRLTIDDKGITVSGITKSYFDTITKMEYNALYNNPA
GSYQTPPNFNNYSVSGGSYDHYFDIDHSLTITNDSAISYGEQTTVTEEQFLKDVHAETDDGTPVTSDFNTVVDFSKPGVY
TVTLNAENAAGLKATPTQVTVTILAKPVITADKSISYTKDSTKTDQQFLQDISAKTSDGSKVTSDFDSVVDLAKVGTYKV
TLNAVSADGLNADPVIVLVNVVEGNEPPTPPAPGPDPTPDPTPNPNNPNINPNPDNGQSANSENASNPSNSEVNAALPNT
GDASQATTVLIGIIIAGVAILFFRQRKHS

Sequences:

>Translated_589_residues
MRKMGVKIGLCVLLMMPFTISFSANVSAEEEISVKAAQDVVNIPDPVLKSYLNGLLGQSSTSDITEAQMDTITNVTISNS
SLTDLTGLDYAHNLTILHLSNTGVTDYALVAKIPSLTNLSIAGDNLTNDSLPDLNNLSNITNLNLSPGKLDNNALTKFNK
MSKLSYLNLDSNPSITNIMPLKSIPNLATLFVQFCGINDFRGIDTFPKLVSLSAYGQNVGRTVLINSSIKSSALNFDEAN
QTIFVPFTLMTERGVNFDGYLFPFTTNTSSASTYFTLNETKIDGSRLTIDDKGITVSGITKSYFDTITKMEYNALYNNPA
GSYQTPPNFNNYSVSGGSYDHYFDIDHSLTITNDSAISYGEQTTVTEEQFLKDVHAETDDGTPVTSDFNTVVDFSKPGVY
TVTLNAENAAGLKATPTQVTVTILAKPVITADKSISYTKDSTKTDQQFLQDISAKTSDGSKVTSDFDSVVDLAKVGTYKV
TLNAVSADGLNADPVIVLVNVVEGNEPPTPPAPGPDPTPDPTPNPNNPNINPNPDNGQSANSENASNPSNSEVNAALPNT
GDASQATTVLIGIIIAGVAILFFRQRKHS
>Mature_589_residues
MRKMGVKIGLCVLLMMPFTISFSANVSAEEEISVKAAQDVVNIPDPVLKSYLNGLLGQSSTSDITEAQMDTITNVTISNS
SLTDLTGLDYAHNLTILHLSNTGVTDYALVAKIPSLTNLSIAGDNLTNDSLPDLNNLSNITNLNLSPGKLDNNALTKFNK
MSKLSYLNLDSNPSITNIMPLKSIPNLATLFVQFCGINDFRGIDTFPKLVSLSAYGQNVGRTVLINSSIKSSALNFDEAN
QTIFVPFTLMTERGVNFDGYLFPFTTNTSSASTYFTLNETKIDGSRLTIDDKGITVSGITKSYFDTITKMEYNALYNNPA
GSYQTPPNFNNYSVSGGSYDHYFDIDHSLTITNDSAISYGEQTTVTEEQFLKDVHAETDDGTPVTSDFNTVVDFSKPGVY
TVTLNAENAAGLKATPTQVTVTILAKPVITADKSISYTKDSTKTDQQFLQDISAKTSDGSKVTSDFDSVVDLAKVGTYKV
TLNAVSADGLNADPVIVLVNVVEGNEPPTPPAPGPDPTPDPTPNPNNPNINPNPDNGQSANSENASNPSNSEVNAALPNT
GDASQATTVLIGIIIAGVAILFFRQRKHS

Specific function: Unknown. A role in virulence could not be demonstrated [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 3 MucBP domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR019931
- InterPro:   IPR012569
- InterPro:   IPR000601
- InterPro:   IPR001899 [H]

Pfam domain/function: PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 63084; Mature: 63084

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: PS50847 GRAM_POS_ANCHORING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKMGVKIGLCVLLMMPFTISFSANVSAEEEISVKAAQDVVNIPDPVLKSYLNGLLGQSS
CCCCCHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
TSDITEAQMDTITNVTISNSSLTDLTGLDYAHNLTILHLSNTGVTDYALVAKIPSLTNLS
CCHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCEEHHHHCCCCCEEE
IAGDNLTNDSLPDLNNLSNITNLNLSPGKLDNNALTKFNKMSKLSYLNLDSNPSITNIMP
EECCCCCCCCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHEEEEECCCCCCEEEEEC
LKSIPNLATLFVQFCGINDFRGIDTFPKLVSLSAYGQNVGRTVLINSSIKSSALNFDEAN
CCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHCCCCCCC
QTIFVPFTLMTERGVNFDGYLFPFTTNTSSASTYFTLNETKIDGSRLTIDDKGITVSGIT
CEEEEEEEEEECCCCCCCCEEEEEECCCCCCEEEEEEECEEECCCEEEEECCCEEEECCH
KSYFDTITKMEYNALYNNPAGSYQTPPNFNNYSVSGGSYDHYFDIDHSLTITNDSAISYG
HHHHHHHHHEEEHHEECCCCCCCCCCCCCCCEECCCCCCCEEEECCCEEEEECCCCCCCC
EQTTVTEEQFLKDVHAETDDGTPVTSDFNTVVDFSKPGVYTVTLNAENAAGLKATPTQVT
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCEEE
VTILAKPVITADKSISYTKDSTKTDQQFLQDISAKTSDGSKVTSDFDSVVDLAKVGTYKV
EEEEECCEEECCCCCEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEE
TLNAVSADGLNADPVIVLVNVVEGNEPPTPPAPGPDPTPDPTPNPNNPNINPNPDNGQSA
EEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NSENASNPSNSEVNAALPNTGDASQATTVLIGIIIAGVAILFFRQRKHS
CCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKMGVKIGLCVLLMMPFTISFSANVSAEEEISVKAAQDVVNIPDPVLKSYLNGLLGQSS
CCCCCHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
TSDITEAQMDTITNVTISNSSLTDLTGLDYAHNLTILHLSNTGVTDYALVAKIPSLTNLS
CCHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCEEHHHHCCCCCEEE
IAGDNLTNDSLPDLNNLSNITNLNLSPGKLDNNALTKFNKMSKLSYLNLDSNPSITNIMP
EECCCCCCCCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHEEEEECCCCCCEEEEEC
LKSIPNLATLFVQFCGINDFRGIDTFPKLVSLSAYGQNVGRTVLINSSIKSSALNFDEAN
CCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHCCCCCCC
QTIFVPFTLMTERGVNFDGYLFPFTTNTSSASTYFTLNETKIDGSRLTIDDKGITVSGIT
CEEEEEEEEEECCCCCCCCEEEEEECCCCCCEEEEEEECEEECCCEEEEECCCEEEECCH
KSYFDTITKMEYNALYNNPAGSYQTPPNFNNYSVSGGSYDHYFDIDHSLTITNDSAISYG
HHHHHHHHHEEEHHEECCCCCCCCCCCCCCCEECCCCCCCEEEECCCEEEEECCCCCCCC
EQTTVTEEQFLKDVHAETDDGTPVTSDFNTVVDFSKPGVYTVTLNAENAAGLKATPTQVT
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCEEE
VTILAKPVITADKSISYTKDSTKTDQQFLQDISAKTSDGSKVTSDFDSVVDLAKVGTYKV
EEEEECCEEECCCCCEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEE
TLNAVSADGLNADPVIVLVNVVEGNEPPTPPAPGPDPTPDPTPNPNNPNINPNPDNGQSA
EEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NSENASNPSNSEVNAALPNTGDASQATTVLIGIIIAGVAILFFRQRKHS
CCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]