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The map label for this gene is licR [H]

Identifier: 226223051

GI number: 226223051

Start: 449554

End: 451515

Strand: Direct

Name: licR [H]

Synonym: Lm4b_00445

Alternate gene names: 226223051

Gene position: 449554-451515 (Clockwise)

Preceding gene: 226223049

Following gene: 226223052

Centisome position: 15.43

GC content: 38.63

Gene sequence:

>1962_bases
ATGAAAGCGGTAACGAAAATGATTGCAAATCGCGAAAAAAATATCATTCAGTTTCTAATGAAGACAGGTCAAACACGTGT
TGGAACTATCGCGAATCATCTCGGACTTTCAGAAAAAACAGTATCAAACTCACTGAAGGAAATCGATGTTTTTCTAAAGG
ATTTTGATATGACAGTGGTCCGTAAACCAAAAATCGGTGTGTATATTGAGGGTGATAACAAGGCTTTTGCCGAAGTTAGC
CGATTTCTAGATAACCAAGTCAGCCCAATCCCATCAACGAAAGAAGAGCGGGTTATCTACATTTTCAGTAAATTGCTTAA
AGCAGACGACTATATCACGATTCATCAGCTTGCAGACGAACTTTACATTAGCCGGAGCACGATTGAGAAAAATATGGTTG
AAGTTACGAAAATGCTGGAAAAAGAAGGTATTACTTTGTATAAGAAACCTAGTAAGGGCATGAAACTCCTTATTAGTGAA
CGAGAAAAGCGCGCCTTAACATCGAAATTTATTAATAATTTTTGGGGCAATAATTGGTATTTAAAGCAAGAAGGCGAAAA
GGTCCTCCAAGCTTTTGACACGATTAAAGCCGATGTCACCGGAATTTTTCCAGAAGAGGGCTTGAAAGAAATCATTGCGA
TTGTTCAAGCATTTAGTGAGCGACATGATTTTGCTTTTACTGATTATGCGTTTCAATCGATTGTCATTCACCTTGCGATT
GCGGTAGAGCGTATTCGAACAGGAGAGTATATCGAAAATGTTGAGAGCGATCCAATGAAAGATGTATTTGATTCGCAGCG
AAACAATACGGAAATCCTCGTTAGCATGCTAGAAGACCGTTTGGATATTAAAATTCCAGCATTTGAAGTCGGCTATATTC
AGTTGCATTTAACAGCAGCATATAACCAACAGCATGATGAGTTACTTGTAAGCGTTCGACCAAAAGAAGACGATGTGGCA
GAATTTGTCAGCACGTGTTTAGCGGAAGGGAATTACGATAAAAGCTTACTGGATGACTTGACGACACACATGAAATCCGC
CATTAACCGGTTAAAACTTGGTATGCATTTTAAAAATCCGTACCTTAGCAAAATTAAGCAAAACTTTCCCCAAGCGTTTG
AAGAAGCGCTATATTTTAAAGCAAAATTTGAACAAAAGTACGATGTGCAAGTGAACGAAGATGAGACGGCGTATATCGCG
CTACATTTTGAGGCATACAAAGAAAGAAGTCGTTCTTTCCCCGACCAAATTCGAGTTGTACTTGTATGCAGTACCGGGCT
TGGTTCATCAAGATTACTTGCGGCGAGAATTAAAAAATATTTTCCAATGATTACGATTGAAAAAATATTATCCGTTCAGG
CGTTAATGGAAACAGAAGTCGATGTGGATTTAGTCATCAGCACGATTTATCTCGAACTGGAAGATATTCCAAGTATTGTT
GTCAGTCCGATGATGAGTAAAGCCGATTTACAACAAGTTGAAAGCCAAATCGAACGAACGAGACGCAAGAAAAAGAAACG
CAGCCAACCATTTGTTGACTTGATTGAACCGAAAACTATTTTTGCGAAGCTAGATGTTGCAACGATGGAAGACGCAATCA
CGCAAATTGGTGATAAGCTTGTGAATCTTGGTATTGCTCAATCAGGGATTGTTGAAAGTGCGCTAAAAAGAGAAGCGTTA
TCGTTCACTTCTTTTGAAGAAATGGCGACACCACACGCAGATCCTGCACTTATTAATGAATCGCACATCGCTATTGCCAC
ACTTAAAAATCCAGTGAAATGGGGCTTAGTCGAGGTGGATAAAATCTTTTTTATCGCTCTGACCGAACAAAATGGCATTA
ATTTAGACGCGATGTATGAACAGTTTTATAAATATATTGATAATAAAAAATGGCTTGAGAAGCTGACACAACTAAAAAGT
GCCGCAGAAATTTATGAGCATTTGTTAAAGGATGGGATGTAA

Upstream 100 bases:

>100_bases
AGCAATATCCCAAAATTACGGTATTCAATGCGGTAATTTTCGTAGTTTTCTGGGGATGAGTCTTTGTAATAGAATAAGCG
TAGGGAAAGGAAAATTAAAA

Downstream 100 bases:

>100_bases
TGGAAGTAAAAGATATTTTAACAAAAGAATTAGTCGTCTTTGATTTAGAGGCGACGACAAAAGAAGCAGCAATTGAAGAA
ATGGCAGAAATGCTAGATGA

Product: transcription antiterminator BglG family

Products: NA

Alternate protein names: Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 653; Mature: 653

Protein sequence:

>653_residues
MKAVTKMIANREKNIIQFLMKTGQTRVGTIANHLGLSEKTVSNSLKEIDVFLKDFDMTVVRKPKIGVYIEGDNKAFAEVS
RFLDNQVSPIPSTKEERVIYIFSKLLKADDYITIHQLADELYISRSTIEKNMVEVTKMLEKEGITLYKKPSKGMKLLISE
REKRALTSKFINNFWGNNWYLKQEGEKVLQAFDTIKADVTGIFPEEGLKEIIAIVQAFSERHDFAFTDYAFQSIVIHLAI
AVERIRTGEYIENVESDPMKDVFDSQRNNTEILVSMLEDRLDIKIPAFEVGYIQLHLTAAYNQQHDELLVSVRPKEDDVA
EFVSTCLAEGNYDKSLLDDLTTHMKSAINRLKLGMHFKNPYLSKIKQNFPQAFEEALYFKAKFEQKYDVQVNEDETAYIA
LHFEAYKERSRSFPDQIRVVLVCSTGLGSSRLLAARIKKYFPMITIEKILSVQALMETEVDVDLVISTIYLELEDIPSIV
VSPMMSKADLQQVESQIERTRRKKKKRSQPFVDLIEPKTIFAKLDVATMEDAITQIGDKLVNLGIAQSGIVESALKREAL
SFTSFEEMATPHADPALINESHIAIATLKNPVKWGLVEVDKIFFIALTEQNGINLDAMYEQFYKYIDNKKWLEKLTQLKS
AAEIYEHLLKDGM

Sequences:

>Translated_653_residues
MKAVTKMIANREKNIIQFLMKTGQTRVGTIANHLGLSEKTVSNSLKEIDVFLKDFDMTVVRKPKIGVYIEGDNKAFAEVS
RFLDNQVSPIPSTKEERVIYIFSKLLKADDYITIHQLADELYISRSTIEKNMVEVTKMLEKEGITLYKKPSKGMKLLISE
REKRALTSKFINNFWGNNWYLKQEGEKVLQAFDTIKADVTGIFPEEGLKEIIAIVQAFSERHDFAFTDYAFQSIVIHLAI
AVERIRTGEYIENVESDPMKDVFDSQRNNTEILVSMLEDRLDIKIPAFEVGYIQLHLTAAYNQQHDELLVSVRPKEDDVA
EFVSTCLAEGNYDKSLLDDLTTHMKSAINRLKLGMHFKNPYLSKIKQNFPQAFEEALYFKAKFEQKYDVQVNEDETAYIA
LHFEAYKERSRSFPDQIRVVLVCSTGLGSSRLLAARIKKYFPMITIEKILSVQALMETEVDVDLVISTIYLELEDIPSIV
VSPMMSKADLQQVESQIERTRRKKKKRSQPFVDLIEPKTIFAKLDVATMEDAITQIGDKLVNLGIAQSGIVESALKREAL
SFTSFEEMATPHADPALINESHIAIATLKNPVKWGLVEVDKIFFIALTEQNGINLDAMYEQFYKYIDNKKWLEKLTQLKS
AAEIYEHLLKDGM
>Mature_653_residues
MKAVTKMIANREKNIIQFLMKTGQTRVGTIANHLGLSEKTVSNSLKEIDVFLKDFDMTVVRKPKIGVYIEGDNKAFAEVS
RFLDNQVSPIPSTKEERVIYIFSKLLKADDYITIHQLADELYISRSTIEKNMVEVTKMLEKEGITLYKKPSKGMKLLISE
REKRALTSKFINNFWGNNWYLKQEGEKVLQAFDTIKADVTGIFPEEGLKEIIAIVQAFSERHDFAFTDYAFQSIVIHLAI
AVERIRTGEYIENVESDPMKDVFDSQRNNTEILVSMLEDRLDIKIPAFEVGYIQLHLTAAYNQQHDELLVSVRPKEDDVA
EFVSTCLAEGNYDKSLLDDLTTHMKSAINRLKLGMHFKNPYLSKIKQNFPQAFEEALYFKAKFEQKYDVQVNEDETAYIA
LHFEAYKERSRSFPDQIRVVLVCSTGLGSSRLLAARIKKYFPMITIEKILSVQALMETEVDVDLVISTIYLELEDIPSIV
VSPMMSKADLQQVESQIERTRRKKKKRSQPFVDLIEPKTIFAKLDVATMEDAITQIGDKLVNLGIAQSGIVESALKREAL
SFTSFEEMATPHADPALINESHIAIATLKNPVKWGLVEVDKIFFIALTEQNGINLDAMYEQFYKYIDNKKWLEKLTQLKS
AAEIYEHLLKDGM

Specific function: Positive regulator of the licABCH operon [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR007737
- InterPro:   IPR011608
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF00359 PTS_EIIA_2; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 74754; Mature: 74754

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVTKMIANREKNIIQFLMKTGQTRVGTIANHLGLSEKTVSNSLKEIDVFLKDFDMTVV
CHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEE
RKPKIGVYIEGDNKAFAEVSRFLDNQVSPIPSTKEERVIYIFSKLLKADDYITIHQLADE
ECCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEHHHHHHH
LYISRSTIEKNMVEVTKMLEKEGITLYKKPSKGMKLLISEREKRALTSKFINNFWGNNWY
HHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
LKQEGEKVLQAFDTIKADVTGIFPEEGLKEIIAIVQAFSERHDFAFTDYAFQSIVIHLAI
ECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHH
AVERIRTGEYIENVESDPMKDVFDSQRNNTEILVSMLEDRLDIKIPAFEVGYIQLHLTAA
HHHHHHCCHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCEECCCEEEEEEEEEEEEC
YNQQHDELLVSVRPKEDDVAEFVSTCLAEGNYDKSLLDDLTTHMKSAINRLKLGMHFKNP
CCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCH
YLSKIKQNFPQAFEEALYFKAKFEQKYDVQVNEDETAYIALHFEAYKERSRSFPDQIRVV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEEEEEEHHHHHHHCCCCCCEEEE
LVCSTGLGSSRLLAARIKKYFPMITIEKILSVQALMETEVDVDLVISTIYLELEDIPSIV
EEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VSPMMSKADLQQVESQIERTRRKKKKRSQPFVDLIEPKTIFAKLDVATMEDAITQIGDKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHEECHHHHHHHHHHHHHHH
VNLGIAQSGIVESALKREALSFTSFEEMATPHADPALINESHIAIATLKNPVKWGLVEVD
HHCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCEEEEEECCCHHCCCEEEC
KIFFIALTEQNGINLDAMYEQFYKYIDNKKWLEKLTQLKSAAEIYEHLLKDGM
EEEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKAVTKMIANREKNIIQFLMKTGQTRVGTIANHLGLSEKTVSNSLKEIDVFLKDFDMTVV
CHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEE
RKPKIGVYIEGDNKAFAEVSRFLDNQVSPIPSTKEERVIYIFSKLLKADDYITIHQLADE
ECCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEHHHHHHH
LYISRSTIEKNMVEVTKMLEKEGITLYKKPSKGMKLLISEREKRALTSKFINNFWGNNWY
HHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
LKQEGEKVLQAFDTIKADVTGIFPEEGLKEIIAIVQAFSERHDFAFTDYAFQSIVIHLAI
ECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHH
AVERIRTGEYIENVESDPMKDVFDSQRNNTEILVSMLEDRLDIKIPAFEVGYIQLHLTAA
HHHHHHCCHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHCCCEECCCEEEEEEEEEEEEC
YNQQHDELLVSVRPKEDDVAEFVSTCLAEGNYDKSLLDDLTTHMKSAINRLKLGMHFKNP
CCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCH
YLSKIKQNFPQAFEEALYFKAKFEQKYDVQVNEDETAYIALHFEAYKERSRSFPDQIRVV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEEEEEEHHHHHHHCCCCCCEEEE
LVCSTGLGSSRLLAARIKKYFPMITIEKILSVQALMETEVDVDLVISTIYLELEDIPSIV
EEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VSPMMSKADLQQVESQIERTRRKKKKRSQPFVDLIEPKTIFAKLDVATMEDAITQIGDKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHEECHHHHHHHHHHHHHHH
VNLGIAQSGIVESALKREALSFTSFEEMATPHADPALINESHIAIATLKNPVKWGLVEVD
HHCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCEEEEEECCCHHCCCEEEC
KIFFIALTEQNGINLDAMYEQFYKYIDNKKWLEKLTQLKSAAEIYEHLLKDGM
EEEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377; 10438772 [H]