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The map label for this gene is licR [H]

Identifier: 226223032

GI number: 226223032

Start: 431069

End: 433003

Strand: Direct

Name: licR [H]

Synonym: Lm4b_00426

Alternate gene names: 226223032

Gene position: 431069-433003 (Clockwise)

Preceding gene: 226223031

Following gene: 226223033

Centisome position: 14.8

GC content: 37.62

Gene sequence:

>1935_bases
ATGGGATATTTCGCTTATAAACGTTTGGAAACACTATATGGCATGCTCCTTGATGCGGGTAGCCACTTATCAGCTCAGAA
ACTCAGCCAAGATTTACATATTTCCGAACGTACGATACGAACAGATATTGCTAAACTAACTGAATTTCTCGAAAGCTACG
GGGCAACGATAACGCTAACTCGAGGCGCGGGATACAAAATCGAAATCCTTGATTCGTTGGTTTTTCAAGCTTTTCAGGCC
GAAAAAAACAAACCAAAAAATGCGGGTTATTTTGACCTTGATAATCCCGAAGAACGCGTGAAATACGAGATTTTCATGCT
GTTATCAAGCGGCGACTATATTAAATTGGAAGACTTGGCAGATACGATTTTTGCTAGCCGTGCAACCATTTCAAATGATA
TGAAGCAAGTACGAAAAGTTATTGCGGTGTATGATTTAACGCTCGTCTCAAAACCAGGTAGCGGCGTGAAAATCATCGGA
GAAGAAGAAAAAATGCGCTATGCTCTAACCGCGTTAATTGCTTCCAAAAACGCCCCGGAATCCTACTTAGAAACATTTTT
CGAATGGCACAAACAAAAAGATAAACTGCAAAAATTAATGACAGCTGTGACGGATTATTTTTTTGCGACCAACATTCGTT
TCACAGACGAAGCGCTTCAAAACTTACTTTTACATATGATGATTTTGGTGGAACGAATTGAACTCGGTCATACGTTGGAA
AAGTTTGAATTAACGGATGTTAGTGAAGAAGAAATCGCGATTGCGACTAAATTGTCTACTATTATAGAGTCGCTTTTCGA
AATAGACATTGCGGATGCGGACAAAAATTATTTGCTTCTCCAAATCGCCAGCAAACGAATTCTGAATGTAGAAGATAAAG
AAATTAGCGAATTTGATGATTACGCGTATATTGAAGGCATGTTGAACCGCATTGAGTCCCATTACTTTTATCATTTACAA
GATGATATGCAGCTTAAAAAGGACCTTGTTGCTCATATTCATTCCATGTTATATCGAGTAAAATACCATATGACCGTCAA
AAATCCAATGACAGAGCACATTAAACGCTATTACCCTTTAGCCTACGAAATCACGCTCGATGCAGTGGAATCACTAAAAA
AAGACTACCCGTATGACATTAATCAAAATGAATTAGCCTATTTAGCGCTGCATATTGGGGCATCCTTAGAGCGGAATTAT
CAAATCTCTTACTATCGTCATAAATCAGCCTTGATTGTTTGTGGGTCAGGCTTTGGAACAGCACGAATTGTAGAAGCGAA
AGTAAAGTCAGCAGTGAGTAATCTCGATATTACAAAAGTAGTTTCAATCCAAGAATATAACCGTTTTATCCATATTGAAG
AAGATATCATTCTCTCCACCGTTAGAATACCTGAGAAAAATAAACCGGTCATCAAAATCAGCAATATCCCAACCAATGAA
GAATTAAAAATGCTTGGTGCCATTATTCAAGAACAAACCGATCCTAACCGCGGCTTTCTATCGAATTTTTTCACAGCTGA
TTTTTTTGCCAGAAGCAGTATGACAAACAAAACAGCAATTTTAGAAGAAATGGTTGACTCATTACGCCAACAAAATATTG
TTGGTGAAGGCTTCTTGCAATCGGTTCTTGAACGTGAAAAATTAGGCTCAACTGTACTCGGAACCGGAATAGCAATCCCA
CATCCACTCGGACTAATGGCCAAAGAAACAAAAATCGTTATTCGGATATTAGATAAACCAATCAAATGGGATCAAAAACA
ATCCGTTCGCGCCGTATTTTTATTATGTATTAGCAAAAATGATTATGAAGAAGCCATTAATATTTATGAATTGCTAGTAG
AATTAGTACGCGAAGAATATGGTGAGAAGCTTTCAAGGCTTTCCGACTTTCATGCATTCACTGCTTTAGCAAATGATATT
TTGAAGAAAAAATAA

Upstream 100 bases:

>100_bases
GCGAATCAAACGAGAAACAAACGAGATTAAAACATGCAAAAGTACAAAGCTATTTATTTGAAAAATAACGCTTAACTACC
TAAAAAAGGAGCTGCTAATA

Downstream 100 bases:

>100_bases
AAGCTACTTCCTTTTTTAGGAAGTGGTTTTTTCGTGAATTTTTCGTGAATTTTACCATTTTTCGTTTAGTGATAGGTTAT
TTCATGGTACACTATAAGAA

Product: transcriptional antiterminator (BglG family)

Products: NA

Alternate protein names: Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 644; Mature: 643

Protein sequence:

>644_residues
MGYFAYKRLETLYGMLLDAGSHLSAQKLSQDLHISERTIRTDIAKLTEFLESYGATITLTRGAGYKIEILDSLVFQAFQA
EKNKPKNAGYFDLDNPEERVKYEIFMLLSSGDYIKLEDLADTIFASRATISNDMKQVRKVIAVYDLTLVSKPGSGVKIIG
EEEKMRYALTALIASKNAPESYLETFFEWHKQKDKLQKLMTAVTDYFFATNIRFTDEALQNLLLHMMILVERIELGHTLE
KFELTDVSEEEIAIATKLSTIIESLFEIDIADADKNYLLLQIASKRILNVEDKEISEFDDYAYIEGMLNRIESHYFYHLQ
DDMQLKKDLVAHIHSMLYRVKYHMTVKNPMTEHIKRYYPLAYEITLDAVESLKKDYPYDINQNELAYLALHIGASLERNY
QISYYRHKSALIVCGSGFGTARIVEAKVKSAVSNLDITKVVSIQEYNRFIHIEEDIILSTVRIPEKNKPVIKISNIPTNE
ELKMLGAIIQEQTDPNRGFLSNFFTADFFARSSMTNKTAILEEMVDSLRQQNIVGEGFLQSVLEREKLGSTVLGTGIAIP
HPLGLMAKETKIVIRILDKPIKWDQKQSVRAVFLLCISKNDYEEAINIYELLVELVREEYGEKLSRLSDFHAFTALANDI
LKKK

Sequences:

>Translated_644_residues
MGYFAYKRLETLYGMLLDAGSHLSAQKLSQDLHISERTIRTDIAKLTEFLESYGATITLTRGAGYKIEILDSLVFQAFQA
EKNKPKNAGYFDLDNPEERVKYEIFMLLSSGDYIKLEDLADTIFASRATISNDMKQVRKVIAVYDLTLVSKPGSGVKIIG
EEEKMRYALTALIASKNAPESYLETFFEWHKQKDKLQKLMTAVTDYFFATNIRFTDEALQNLLLHMMILVERIELGHTLE
KFELTDVSEEEIAIATKLSTIIESLFEIDIADADKNYLLLQIASKRILNVEDKEISEFDDYAYIEGMLNRIESHYFYHLQ
DDMQLKKDLVAHIHSMLYRVKYHMTVKNPMTEHIKRYYPLAYEITLDAVESLKKDYPYDINQNELAYLALHIGASLERNY
QISYYRHKSALIVCGSGFGTARIVEAKVKSAVSNLDITKVVSIQEYNRFIHIEEDIILSTVRIPEKNKPVIKISNIPTNE
ELKMLGAIIQEQTDPNRGFLSNFFTADFFARSSMTNKTAILEEMVDSLRQQNIVGEGFLQSVLEREKLGSTVLGTGIAIP
HPLGLMAKETKIVIRILDKPIKWDQKQSVRAVFLLCISKNDYEEAINIYELLVELVREEYGEKLSRLSDFHAFTALANDI
LKKK
>Mature_643_residues
GYFAYKRLETLYGMLLDAGSHLSAQKLSQDLHISERTIRTDIAKLTEFLESYGATITLTRGAGYKIEILDSLVFQAFQAE
KNKPKNAGYFDLDNPEERVKYEIFMLLSSGDYIKLEDLADTIFASRATISNDMKQVRKVIAVYDLTLVSKPGSGVKIIGE
EEKMRYALTALIASKNAPESYLETFFEWHKQKDKLQKLMTAVTDYFFATNIRFTDEALQNLLLHMMILVERIELGHTLEK
FELTDVSEEEIAIATKLSTIIESLFEIDIADADKNYLLLQIASKRILNVEDKEISEFDDYAYIEGMLNRIESHYFYHLQD
DMQLKKDLVAHIHSMLYRVKYHMTVKNPMTEHIKRYYPLAYEITLDAVESLKKDYPYDINQNELAYLALHIGASLERNYQ
ISYYRHKSALIVCGSGFGTARIVEAKVKSAVSNLDITKVVSIQEYNRFIHIEEDIILSTVRIPEKNKPVIKISNIPTNEE
LKMLGAIIQEQTDPNRGFLSNFFTADFFARSSMTNKTAILEEMVDSLRQQNIVGEGFLQSVLEREKLGSTVLGTGIAIPH
PLGLMAKETKIVIRILDKPIKWDQKQSVRAVFLLCISKNDYEEAINIYELLVELVREEYGEKLSRLSDFHAFTALANDIL
KKK

Specific function: Positive regulator of the licABCH operon [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR007737
- InterPro:   IPR011608
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF00359 PTS_EIIA_2; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 73875; Mature: 73744

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYFAYKRLETLYGMLLDAGSHLSAQKLSQDLHISERTIRTDIAKLTEFLESYGATITLT
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEE
RGAGYKIEILDSLVFQAFQAEKNKPKNAGYFDLDNPEERVKYEIFMLLSSGDYIKLEDLA
CCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHEEEEEEEECCCCEEEHHHHH
DTIFASRATISNDMKQVRKVIAVYDLTLVSKPGSGVKIIGEEEKMRYALTALIASKNAPE
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEECCHHHHHHHHHHHHHCCCCCH
SYLETFFEWHKQKDKLQKLMTAVTDYFFATNIRFTDEALQNLLLHMMILVERIELGHTLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHH
KFELTDVSEEEIAIATKLSTIIESLFEIDIADADKNYLLLQIASKRILNVEDKEISEFDD
HEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHCCCCCHHHHHHHH
YAYIEGMLNRIESHYFYHLQDDMQLKKDLVAHIHSMLYRVKYHMTVKNPMTEHIKRYYPL
HHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHCCE
AYEITLDAVESLKKDYPYDINQNELAYLALHIGASLERNYQISYYRHKSALIVCGSGFGT
EEEEEHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEECCEEEEEECCCCC
ARIVEAKVKSAVSNLDITKVVSIQEYNRFIHIEEDIILSTVRIPEKNKPVIKISNIPTNE
HHHHHHHHHHHHHCCCHHHEEEHHHCCCEEEECHHHEEEEEECCCCCCCEEEECCCCCCH
ELKMLGAIIQEQTDPNRGFLSNFFTADFFARSSMTNKTAILEEMVDSLRQQNIVGEGFLQ
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHH
SVLEREKLGSTVLGTGIAIPHPLGLMAKETKIVIRILDKPIKWDQKQSVRAVFLLCISKN
HHHHHHHCCCEECCCCCCCCCCCCCHHHHHHHHHEECCCCCCCCCHHHHEEEEEEEECCC
DYEEAINIYELLVELVREEYGEKLSRLSDFHAFTALANDILKKK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GYFAYKRLETLYGMLLDAGSHLSAQKLSQDLHISERTIRTDIAKLTEFLESYGATITLT
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEE
RGAGYKIEILDSLVFQAFQAEKNKPKNAGYFDLDNPEERVKYEIFMLLSSGDYIKLEDLA
CCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHEEEEEEEECCCCEEEHHHHH
DTIFASRATISNDMKQVRKVIAVYDLTLVSKPGSGVKIIGEEEKMRYALTALIASKNAPE
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEECCHHHHHHHHHHHHHCCCCCH
SYLETFFEWHKQKDKLQKLMTAVTDYFFATNIRFTDEALQNLLLHMMILVERIELGHTLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHH
KFELTDVSEEEIAIATKLSTIIESLFEIDIADADKNYLLLQIASKRILNVEDKEISEFDD
HEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHCCCCCHHHHHHHH
YAYIEGMLNRIESHYFYHLQDDMQLKKDLVAHIHSMLYRVKYHMTVKNPMTEHIKRYYPL
HHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHCCE
AYEITLDAVESLKKDYPYDINQNELAYLALHIGASLERNYQISYYRHKSALIVCGSGFGT
EEEEEHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEECCEEEEEECCCCC
ARIVEAKVKSAVSNLDITKVVSIQEYNRFIHIEEDIILSTVRIPEKNKPVIKISNIPTNE
HHHHHHHHHHHHHCCCHHHEEEHHHCCCEEEECHHHEEEEEECCCCCCCEEEECCCCCCH
ELKMLGAIIQEQTDPNRGFLSNFFTADFFARSSMTNKTAILEEMVDSLRQQNIVGEGFLQ
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHH
SVLEREKLGSTVLGTGIAIPHPLGLMAKETKIVIRILDKPIKWDQKQSVRAVFLLCISKN
HHHHHHHCCCEECCCCCCCCCCCCCHHHHHHHHHEECCCCCCCCCHHHHEEEEEEEECCC
DYEEAINIYELLVELVREEYGEKLSRLSDFHAFTALANDILKKK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377; 10438772 [H]