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The map label for this gene is macB [H]

Identifier: 226223025

GI number: 226223025

Start: 424422

End: 425600

Strand: Direct

Name: macB [H]

Synonym: Lm4b_00419b

Alternate gene names: 226223025

Gene position: 424422-425600 (Clockwise)

Preceding gene: 226223024

Following gene: 226223026

Centisome position: 14.57

GC content: 35.71

Gene sequence:

>1179_bases
ATGGAACAAATTATGACTCTTTTACAGAGTATAAAGTTAGCGCTAAAACAATTATTGTCCACCAAATTTCGAACATTTTT
AACAATGCTTGGAATTATTATTGGTGTTTTTTCTGTTATATTACTTGTTTCGATTGGGGAAGCTATATCGAAAAATGTCT
CCACACAATTAGGTGATATGGGAAGTAATCTTTTGACTGTTAATTTTTATTCAGATAATCCAAACGATAAATTCACATAC
AAAGATGCAAAAAAACTTTTGAATGAAGATGAAATTGGTTCGCCGGAAGTGATGCAGACAAAGGAAGTTAGAACAAGTGA
AAAGACAGCTAGTAATCAAGTAGCGGGAATAAATGAATATTATGCGAGCATAAAAAATTTGGAATTAGCATCAGGCCGTT
TTTGCTCGAATGTAGATGTTATCTATGCCCAAAAAGTGACAATTATTGGCTCAGAAATTGCAAAAACTTATTTTAAAGAA
CAGAATCCGATAGGTGAATATTTGCAAATTGCAGGTGCTAGGTACATGGTCATTGGAGTTTTAAAGGAAAAGGGGGAGAG
TTTATTTGGATCGGCAGACAAAAAACTTTTTATCCCAATTTCTTCCGCAGAACGACTTTTTAAAACAGATACTGTGGATT
TGTATTATATTCAAACAAAAAAAGTAGAACAAGTTCCAGCAGCAGTTAAGGTAGTAAAGAAAAAAATGCGCCAGTTTTTT
CCGAATAATGAAGATGCGTATACGGTTGTAAACCAGCAACAGGCGTTAGATACGTTTGATAGTATTACGGGAACACTCAC
GATTGGACTAGGTGCGATTGCAGGGATTTCGCTACTCGTTGGCGGTATTGGTATTATGAATATTATGCTCGTGTCTGTCT
CAGAACGAACCCGAGAAATTGGAATTAGAAAAGCGATTGGCGCAAGTAGTGGCAATATTTTAATGCAGTTTTTGATTGAA
GCAGTTGTGCTTAGTTTAGTAGGCGGTTGTATCGGGATTTTACTAGGAATTTTTTCCGCGCAAATAGTTACAACTACATC
AAGTTTTGAAATGTATGTTTCTGCTTCTACGATTCTTTTAGCGGTTGGTTTTTCGATGTGTATTGGGATTGTATTTGGTG
TAATTCCCGCACAGAAAGCTTCAAAAAAAAAGCCGATAGATGCGTTACGGGCAGATTAA

Upstream 100 bases:

>100_bases
TTCATAGAGAAGGAAATACATTAATCATGATTACCCACGACAAAGAAATTGCAAATCAAGCAGAACGAATAATAGAAATA
AAAGACGGAAAACTCCGTGA

Downstream 100 bases:

>100_bases
CTAGAGGAGGCGTGTTGGATGGAGAAAGAGCAACAAACGGATGATACTTGGGTTTTAGTTGAAATTGTTAGCCTTATAAC
CAACGTGGAACGACAAAGAT

Product: ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MEQIMTLLQSIKLALKQLLSTKFRTFLTMLGIIIGVFSVILLVSIGEAISKNVSTQLGDMGSNLLTVNFYSDNPNDKFTY
KDAKKLLNEDEIGSPEVMQTKEVRTSEKTASNQVAGINEYYASIKNLELASGRFCSNVDVIYAQKVTIIGSEIAKTYFKE
QNPIGEYLQIAGARYMVIGVLKEKGESLFGSADKKLFIPISSAERLFKTDTVDLYYIQTKKVEQVPAAVKVVKKKMRQFF
PNNEDAYTVVNQQQALDTFDSITGTLTIGLGAIAGISLLVGGIGIMNIMLVSVSERTREIGIRKAIGASSGNILMQFLIE
AVVLSLVGGCIGILLGIFSAQIVTTTSSFEMYVSASTILLAVGFSMCIGIVFGVIPAQKASKKKPIDALRAD

Sequences:

>Translated_392_residues
MEQIMTLLQSIKLALKQLLSTKFRTFLTMLGIIIGVFSVILLVSIGEAISKNVSTQLGDMGSNLLTVNFYSDNPNDKFTY
KDAKKLLNEDEIGSPEVMQTKEVRTSEKTASNQVAGINEYYASIKNLELASGRFCSNVDVIYAQKVTIIGSEIAKTYFKE
QNPIGEYLQIAGARYMVIGVLKEKGESLFGSADKKLFIPISSAERLFKTDTVDLYYIQTKKVEQVPAAVKVVKKKMRQFF
PNNEDAYTVVNQQQALDTFDSITGTLTIGLGAIAGISLLVGGIGIMNIMLVSVSERTREIGIRKAIGASSGNILMQFLIE
AVVLSLVGGCIGILLGIFSAQIVTTTSSFEMYVSASTILLAVGFSMCIGIVFGVIPAQKASKKKPIDALRAD
>Mature_392_residues
MEQIMTLLQSIKLALKQLLSTKFRTFLTMLGIIIGVFSVILLVSIGEAISKNVSTQLGDMGSNLLTVNFYSDNPNDKFTY
KDAKKLLNEDEIGSPEVMQTKEVRTSEKTASNQVAGINEYYASIKNLELASGRFCSNVDVIYAQKVTIIGSEIAKTYFKE
QNPIGEYLQIAGARYMVIGVLKEKGESLFGSADKKLFIPISSAERLFKTDTVDLYYIQTKKVEQVPAAVKVVKKKMRQFF
PNNEDAYTVVNQQQALDTFDSITGTLTIGLGAIAGISLLVGGIGIMNIMLVSVSERTREIGIRKAIGASSGNILMQFLIE
AVVLSLVGGCIGILLGIFSAQIVTTTSSFEMYVSASTILLAVGFSMCIGIVFGVIPAQKASKKKPIDALRAD

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=401, Percent_Identity=32.4189526184539, Blast_Score=173, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42604; Mature: 42604

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQIMTLLQSIKLALKQLLSTKFRTFLTMLGIIIGVFSVILLVSIGEAISKNVSTQLGDM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GSNLLTVNFYSDNPNDKFTYKDAKKLLNEDEIGSPEVMQTKEVRTSEKTASNQVAGINEY
CCCEEEEEEECCCCCCCEEHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHH
YASIKNLELASGRFCSNVDVIYAQKVTIIGSEIAKTYFKEQNPIGEYLQIAGARYMVIGV
HHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEHH
LKEKGESLFGSADKKLFIPISSAERLFKTDTVDLYYIQTKKVEQVPAAVKVVKKKMRQFF
HHHHCCHHCCCCCCEEEEEECHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHC
PNNEDAYTVVNQQQALDTFDSITGTLTIGLGAIAGISLLVGGIGIMNIMLVSVSERTREI
CCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIRKAIGASSGNILMQFLIEAVVLSLVGGCIGILLGIFSAQIVTTTSSFEMYVSASTILL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEHHHHHHH
AVGFSMCIGIVFGVIPAQKASKKKPIDALRAD
HHHHHHHHHHHHHHCCCHHCCCCCCCHHHCCC
>Mature Secondary Structure
MEQIMTLLQSIKLALKQLLSTKFRTFLTMLGIIIGVFSVILLVSIGEAISKNVSTQLGDM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GSNLLTVNFYSDNPNDKFTYKDAKKLLNEDEIGSPEVMQTKEVRTSEKTASNQVAGINEY
CCCEEEEEEECCCCCCCEEHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHH
YASIKNLELASGRFCSNVDVIYAQKVTIIGSEIAKTYFKEQNPIGEYLQIAGARYMVIGV
HHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEHH
LKEKGESLFGSADKKLFIPISSAERLFKTDTVDLYYIQTKKVEQVPAAVKVVKKKMRQFF
HHHHCCHHCCCCCCEEEEEECHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHC
PNNEDAYTVVNQQQALDTFDSITGTLTIGLGAIAGISLLVGGIGIMNIMLVSVSERTREI
CCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIRKAIGASSGNILMQFLIEAVVLSLVGGCIGILLGIFSAQIVTTTSSFEMYVSASTILL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEHHHHHHH
AVGFSMCIGIVFGVIPAQKASKKKPIDALRAD
HHHHHHHHHHHHHHCCCHHCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA