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The map label for this gene is inlA [H]

Identifier: 226222980

GI number: 226222980

Start: 380374

End: 382143

Strand: Direct

Name: inlA [H]

Synonym: Lm4b_00372

Alternate gene names: 226222980

Gene position: 380374-382143 (Clockwise)

Preceding gene: 226222979

Following gene: 226222982

Centisome position: 13.06

GC content: 37.4

Gene sequence:

>1770_bases
ATGAAATCCAAAGGGAGACTGTTTTTGTACGTTGTTTTGGCGTTGTCGATTGTTATTGGGACGAATGTATTTATAAAAAT
AGACGCACATGCAGCCGCTGCACCACCAGCTGCAATCAGCCAGATTTTTCCCGATGATGCTTTAGCGACAGAAATTCAAA
CTACACTCGGAAAGTCTAGTACAGCAGAGGTTGTCACTCAAACAGATTTAGATACTATTAATTCATTAACCCTTACTTCT
AAAGGTATCAGCTCCCTAGAAGGTATGAACTACTTGACCAATTTAGGAACTTTAATTTTAACTGGTAATCAAGTAAGCGA
TATTTCGCCACTTAAAGGCTTAACTAACTTGACCATGCTTCAGCTGAGTGGAAATCCGATTAGCGACATTAGCGCACTTA
GTAACTTGAAAAACTTACAAGCTCTAGATATTAACGACGCGCAAGTTACTGACATCACGCCACTGAGCGGTTTAACAAAT
CTAAAGGGTTTAGGCTTATATAATAATCAATTGGAGAACCTTAGTGGAGTAAATAGTTTACATCAACTCCGCTCCTTAAA
TGTTAGTAATAATAAGCTTACGAACCTAGATGAGCTACAAGCGCTAAGCAATTTAAGCGTTCTATATGCAAATGAAAACC
AAATTAACAATCTTCAGGGGCTAAGTAATTTAAATAACCTTTTCTTGCTTGATTTATCAGCGAACCAAATTGTGGATACT
ACTCCACTCGCTGGCTTAACTAAGGTACAAACATTATACGTATCAAACAATCAAATTAGTGATGTAACTGGTCTTTCGAG
TTTAATAAATCTAGATTGGCTCGATATAAGTCAAAATAAAATTAGTAACATTAGACCTTTAAACAGTTTAACGAAGCTAA
CAATTATTCAAATGACTAATCAATTAATCGTAAACGAACCGATAAGTTTCGAAAGCACTGTAACGATTCCTAATTTAATA
AAAAACATTGCGGAACAAACGATTGATCCCGATACAATTAGCGATAACGGTGTGTATGCGAATGAAGCTGTTACATGGAA
TTTACCTACTTATATTCCTAAAGTCAGCTATACCTTTATTGAACGTGATACGATTGGTAATGCAACTGGAAATTTCAGTG
GGACTGTAGAACAGCCATTAGTACAATATTTTAAAGCAACTTTCAATATTGACGGGCAAGAAACAACGGAAAATGTCGAA
ACAGGGACACTTTTACAAGAACCACCAACCCCAGTCAAAGAGGGTTATACATTTAACGGATGGTATGATGCTGAAACAGG
TGGAACAAAATGGGACTTTACAGCCGATACGATGCCAGCAAATGATATAACGTTGTATGCCCAGTTTAGTATTAATAGTT
ATACCGCAACTTTTGATGTAGATGGCGTCATTTCTACTCAAGCGGTAGAGTATCAAGGTTTACTGGAAGAGCCACCAGCG
CCAACTAAGGATGGTTATACATTTAAAGGTTGGTATGATGCCAAAACTGGTGGAACAAAATGGGACTTCACAAACAATCA
AATGCCAGCAAATGATATAACCTTGTATGCCCAGTTTAGTAAAGATGCATCTTCTGGTGGGGACGGTGGAGGAACCGATG
AAGGTGGAGGTAACTCTGAAAATAGTACAGAGGGAGCTCCTAATACGAGTGATATAGATACTATAAACCACATCGTACTA
CCAGCAACAGGAGATGACCATGTGCTTTTTCCAATCTTTATTGGAACATTTCTTACGAGTTTAGCATTACTTACACTTAG
AAGAAAATAA

Upstream 100 bases:

>100_bases
TGAAAACAGCTCGGGGACGCCCTCAAGCTGTTTTTTTATGTTTCTGGTGATAAGAAAATGGGAACAAGATACTATTAAAC
TTTTTGTCAGGGGGAGCAAG

Downstream 100 bases:

>100_bases
AGGAAAAAGCAGCTGCATAACGCAGCTGCTTTTTTGAAACTTATTTTTTCAATTCTCGTTCCATCTGCAAACGTTGTACT
TTCATTGTTGCAGTACGAGG

Product: internalin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 589; Mature: 589

Protein sequence:

>589_residues
MKSKGRLFLYVVLALSIVIGTNVFIKIDAHAAAAPPAAISQIFPDDALATEIQTTLGKSSTAEVVTQTDLDTINSLTLTS
KGISSLEGMNYLTNLGTLILTGNQVSDISPLKGLTNLTMLQLSGNPISDISALSNLKNLQALDINDAQVTDITPLSGLTN
LKGLGLYNNQLENLSGVNSLHQLRSLNVSNNKLTNLDELQALSNLSVLYANENQINNLQGLSNLNNLFLLDLSANQIVDT
TPLAGLTKVQTLYVSNNQISDVTGLSSLINLDWLDISQNKISNIRPLNSLTKLTIIQMTNQLIVNEPISFESTVTIPNLI
KNIAEQTIDPDTISDNGVYANEAVTWNLPTYIPKVSYTFIERDTIGNATGNFSGTVEQPLVQYFKATFNIDGQETTENVE
TGTLLQEPPTPVKEGYTFNGWYDAETGGTKWDFTADTMPANDITLYAQFSINSYTATFDVDGVISTQAVEYQGLLEEPPA
PTKDGYTFKGWYDAKTGGTKWDFTNNQMPANDITLYAQFSKDASSGGDGGGTDEGGGNSENSTEGAPNTSDIDTINHIVL
PATGDDHVLFPIFIGTFLTSLALLTLRRK

Sequences:

>Translated_589_residues
MKSKGRLFLYVVLALSIVIGTNVFIKIDAHAAAAPPAAISQIFPDDALATEIQTTLGKSSTAEVVTQTDLDTINSLTLTS
KGISSLEGMNYLTNLGTLILTGNQVSDISPLKGLTNLTMLQLSGNPISDISALSNLKNLQALDINDAQVTDITPLSGLTN
LKGLGLYNNQLENLSGVNSLHQLRSLNVSNNKLTNLDELQALSNLSVLYANENQINNLQGLSNLNNLFLLDLSANQIVDT
TPLAGLTKVQTLYVSNNQISDVTGLSSLINLDWLDISQNKISNIRPLNSLTKLTIIQMTNQLIVNEPISFESTVTIPNLI
KNIAEQTIDPDTISDNGVYANEAVTWNLPTYIPKVSYTFIERDTIGNATGNFSGTVEQPLVQYFKATFNIDGQETTENVE
TGTLLQEPPTPVKEGYTFNGWYDAETGGTKWDFTADTMPANDITLYAQFSINSYTATFDVDGVISTQAVEYQGLLEEPPA
PTKDGYTFKGWYDAKTGGTKWDFTNNQMPANDITLYAQFSKDASSGGDGGGTDEGGGNSENSTEGAPNTSDIDTINHIVL
PATGDDHVLFPIFIGTFLTSLALLTLRRK
>Mature_589_residues
MKSKGRLFLYVVLALSIVIGTNVFIKIDAHAAAAPPAAISQIFPDDALATEIQTTLGKSSTAEVVTQTDLDTINSLTLTS
KGISSLEGMNYLTNLGTLILTGNQVSDISPLKGLTNLTMLQLSGNPISDISALSNLKNLQALDINDAQVTDITPLSGLTN
LKGLGLYNNQLENLSGVNSLHQLRSLNVSNNKLTNLDELQALSNLSVLYANENQINNLQGLSNLNNLFLLDLSANQIVDT
TPLAGLTKVQTLYVSNNQISDVTGLSSLINLDWLDISQNKISNIRPLNSLTKLTIIQMTNQLIVNEPISFESTVTIPNLI
KNIAEQTIDPDTISDNGVYANEAVTWNLPTYIPKVSYTFIERDTIGNATGNFSGTVEQPLVQYFKATFNIDGQETTENVE
TGTLLQEPPTPVKEGYTFNGWYDAETGGTKWDFTADTMPANDITLYAQFSINSYTATFDVDGVISTQAVEYQGLLEEPPA
PTKDGYTFKGWYDAKTGGTKWDFTNNQMPANDITLYAQFSKDASSGGDGGGTDEGGGNSENSTEGAPNTSDIDTINHIVL
PATGDDHVLFPIFIGTFLTSLALLTLRRK

Specific function: Mediates the entry of Listeria monocytogenes into cells [H]

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 14 LRR (leucine-rich) repeats [H]

Homologues:

Organism=Homo sapiens, GI4506013, Length=242, Percent_Identity=32.2314049586777, Blast_Score=109, Evalue=9e-24,
Organism=Homo sapiens, GI21389483, Length=205, Percent_Identity=31.219512195122, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI55743114, Length=156, Percent_Identity=32.0512820512821, Blast_Score=71, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17531555, Length=217, Percent_Identity=29.0322580645161, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17536161, Length=197, Percent_Identity=32.994923857868, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17554124, Length=201, Percent_Identity=30.8457711442786, Blast_Score=88, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6322655, Length=305, Percent_Identity=28.8524590163934, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21358617, Length=262, Percent_Identity=30.1526717557252, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI17933612, Length=202, Percent_Identity=31.6831683168317, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24584272, Length=289, Percent_Identity=29.757785467128, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24667524, Length=215, Percent_Identity=30.2325581395349, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR019948
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR013378
- InterPro:   IPR019931
- InterPro:   IPR012569
- InterPro:   IPR001899 [H]

Pfam domain/function: PF09479 Flg_new; PF00746 Gram_pos_anchor; PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 63567; Mature: 63567

Theoretical pI: Translated: 4.04; Mature: 4.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKGRLFLYVVLALSIVIGTNVFIKIDAHAAAAPPAAISQIFPDDALATEIQTTLGKSS
CCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCC
TAEVVTQTDLDTINSLTLTSKGISSLEGMNYLTNLGTLILTGNQVSDISPLKGLTNLTML
CHHEEEECCHHHHCEEEEECCCHHHHHHHHHHHCCCEEEEECCCCCCCCHHCCCCCEEEE
QLSGNPISDISALSNLKNLQALDINDAQVTDITPLSGLTNLKGLGLYNNQLENLSGVNSL
EECCCCCHHHHHHHHHCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH
HQLRSLNVSNNKLTNLDELQALSNLSVLYANENQINNLQGLSNLNNLFLLDLSANQIVDT
HHHHHCCCCCCCCCCHHHHHHHHCCEEEEECCCCCCHHHHHCCCCCEEEEEECCCCEECC
TPLAGLTKVQTLYVSNNQISDVTGLSSLINLDWLDISQNKISNIRPLNSLTKLTIIQMTN
CCCCCCEEEEEEEECCCCCCHHHHHHHHHCCEEEECCCHHHCCCCCCHHHHHEEEEEECC
QLIVNEPISFESTVTIPNLIKNIAEQTIDPDTISDNGVYANEAVTWNLPTYIPKVSYTFI
HHEECCCCCCCCEECHHHHHHHHHHHCCCCCCCCCCCEEECCEEEECCCCCCCCCEEEEE
ERDTIGNATGNFSGTVEQPLVQYFKATFNIDGQETTENVETGTLLQEPPTPVKEGYTFNG
ECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCHHCCEEECC
WYDAETGGTKWDFTADTMPANDITLYAQFSINSYTATFDVDGVISTQAVEYQGLLEEPPA
EEECCCCCCEEEEECCCCCCCCEEEEEEEEECCEEEEEECCCCEECCEEEECCHHCCCCC
PTKDGYTFKGWYDAKTGGTKWDFTNNQMPANDITLYAQFSKDASSGGDGGGTDEGGGNSE
CCCCCEEEEEEEECCCCCCEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCC
NSTEGAPNTSDIDTINHIVLPATGDDHVLFPIFIGTFLTSLALLTLRRK
CCCCCCCCCCCCCCCCEEEEECCCCCCEEHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKSKGRLFLYVVLALSIVIGTNVFIKIDAHAAAAPPAAISQIFPDDALATEIQTTLGKSS
CCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCC
TAEVVTQTDLDTINSLTLTSKGISSLEGMNYLTNLGTLILTGNQVSDISPLKGLTNLTML
CHHEEEECCHHHHCEEEEECCCHHHHHHHHHHHCCCEEEEECCCCCCCCHHCCCCCEEEE
QLSGNPISDISALSNLKNLQALDINDAQVTDITPLSGLTNLKGLGLYNNQLENLSGVNSL
EECCCCCHHHHHHHHHCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH
HQLRSLNVSNNKLTNLDELQALSNLSVLYANENQINNLQGLSNLNNLFLLDLSANQIVDT
HHHHHCCCCCCCCCCHHHHHHHHCCEEEEECCCCCCHHHHHCCCCCEEEEEECCCCEECC
TPLAGLTKVQTLYVSNNQISDVTGLSSLINLDWLDISQNKISNIRPLNSLTKLTIIQMTN
CCCCCCEEEEEEEECCCCCCHHHHHHHHHCCEEEECCCHHHCCCCCCHHHHHEEEEEECC
QLIVNEPISFESTVTIPNLIKNIAEQTIDPDTISDNGVYANEAVTWNLPTYIPKVSYTFI
HHEECCCCCCCCEECHHHHHHHHHHHCCCCCCCCCCCEEECCEEEECCCCCCCCCEEEEE
ERDTIGNATGNFSGTVEQPLVQYFKATFNIDGQETTENVETGTLLQEPPTPVKEGYTFNG
ECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCHHCCEEECC
WYDAETGGTKWDFTADTMPANDITLYAQFSINSYTATFDVDGVISTQAVEYQGLLEEPPA
EEECCCCCCEEEEECCCCCCCCEEEEEEEEECCEEEEEECCCCEECCEEEECCHHCCCCC
PTKDGYTFKGWYDAKTGGTKWDFTNNQMPANDITLYAQFSKDASSGGDGGGTDEGGGNSE
CCCCCEEEEEEEECCCCCCEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCC
NSTEGAPNTSDIDTINHIVLPATGDDHVLFPIFIGTFLTSLALLTLRRK
CCCCCCCCCCCCCCCCEEEEECCCCCCEEHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9541569 [H]