Click here to switch to the map view.

The map label for this gene is gpmB [H]

Identifier: 226222903

GI number: 226222903

Start: 297213

End: 297848

Strand: Direct

Name: gpmB [H]

Synonym: Lm4b_00295

Alternate gene names: 226222903

Gene position: 297213-297848 (Clockwise)

Preceding gene: 226222902

Following gene: 226222904

Centisome position: 10.2

GC content: 42.61

Gene sequence:

>636_bases
TTGGCAGAAGGTTTACGTACAATTTATTTTGTAAGACATGGTAAGACGGAATGGAATATGACTGGACAAATGCAGGGATG
GGGCGATTCGCCGCTAGTTGCAGAAGGTATTGACGGGGCAAAAGCAGTTGGCGAAGTGTTGAAAGATACACCAATTGATG
CGGTTTATACAAGTACAAGTAAACGCACGCAAGATACCGCGGCTTACATTCTTGGCGACCGCGAAATCGAAATTCAACCT
CTGGAAGAACTAAAAGAAATGGGATTTGGAACGTGGGAAGGCATTAGAGTAACTGAAATTGACGAACAACACCCTGAAGA
ACGCGCAAAAATTCTCCATAGCCCAGAAACCTACAAAGCAGAAGTGAACGGCGGCGAGACTTATTATGAACTTGCAGAAC
GACTGTTAGAAGGCGTCGAAAAAATCATTGCAGAAAATCTAAGCGGCAACATTCTCGTCGTTTCTCACGGCATGTCGCTC
ACGTTATTATTATACTTGCTGCAAGGCGGAACGGTTGAAGATCACCGCAAAGAAGCGCCAAGAATCTTGAACACAAGTAT
TAGCATCGTAGAATACCAAAACGGCGAATTTTCTCTTAAAAAAATCAATGAAATCGGTCATTTAGACTTAAAATAA

Upstream 100 bases:

>100_bases
ATTTAAAACCACTTGATACAGATAAATAAATAAGAAAACCTTGAAAATATGCCTATTCATGATACAATTTTAGAAGAATG
TGTAATTAGGAGGCAGAATT

Downstream 100 bases:

>100_bases
GTAGAATCTTGGACATATCTCATTGGAGGTGTGTCCTAGATTTATACATAAGAGAAAGCTAGAAAAAGGGAGAAAACATA
CATATGAAAAGAATTGTCAA

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: PGAM; Phosphoglyceromutase [H]

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MAEGLRTIYFVRHGKTEWNMTGQMQGWGDSPLVAEGIDGAKAVGEVLKDTPIDAVYTSTSKRTQDTAAYILGDREIEIQP
LEELKEMGFGTWEGIRVTEIDEQHPEERAKILHSPETYKAEVNGGETYYELAERLLEGVEKIIAENLSGNILVVSHGMSL
TLLLYLLQGGTVEDHRKEAPRILNTSISIVEYQNGEFSLKKINEIGHLDLK

Sequences:

>Translated_211_residues
MAEGLRTIYFVRHGKTEWNMTGQMQGWGDSPLVAEGIDGAKAVGEVLKDTPIDAVYTSTSKRTQDTAAYILGDREIEIQP
LEELKEMGFGTWEGIRVTEIDEQHPEERAKILHSPETYKAEVNGGETYYELAERLLEGVEKIIAENLSGNILVVSHGMSL
TLLLYLLQGGTVEDHRKEAPRILNTSISIVEYQNGEFSLKKINEIGHLDLK
>Mature_210_residues
AEGLRTIYFVRHGKTEWNMTGQMQGWGDSPLVAEGIDGAKAVGEVLKDTPIDAVYTSTSKRTQDTAAYILGDREIEIQPL
EELKEMGFGTWEGIRVTEIDEQHPEERAKILHSPETYKAEVNGGETYYELAERLLEGVEKIIAENLSGNILVVSHGMSLT
LLLYLLQGGTVEDHRKEAPRILNTSISIVEYQNGEFSLKKINEIGHLDLK

Specific function: Converts N1-(5-Phospho-Alpha-D-Ribosyl)-5,6- Dimethylbenzimidazole Into N1-Alpha-D-Ribosyl-5,6- Dimethylbenzimidazole; Involved In The Assembly Of The Nucleotide Loop Of Cobalamin. [C]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. GpmB subfamily [H]

Homologues:

Organism=Homo sapiens, GI64762406, Length=172, Percent_Identity=37.2093023255814, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI64762445, Length=172, Percent_Identity=37.2093023255814, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI118582286, Length=172, Percent_Identity=33.7209302325581, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1786857, Length=174, Percent_Identity=31.6091954022989, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790856, Length=207, Percent_Identity=29.4685990338164, Blast_Score=80, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6324857, Length=211, Percent_Identity=28.436018957346, Blast_Score=73, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24643264, Length=167, Percent_Identity=34.7305389221557, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24643254, Length=167, Percent_Identity=34.7305389221557, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24643260, Length=167, Percent_Identity=34.7305389221557, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24643258, Length=167, Percent_Identity=34.7305389221557, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24643256, Length=167, Percent_Identity=34.7305389221557, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24643262, Length=167, Percent_Identity=34.7305389221557, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24643252, Length=167, Percent_Identity=34.7305389221557, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI17137706, Length=167, Percent_Identity=34.7305389221557, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR023086 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 23588; Mature: 23457

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEGLRTIYFVRHGKTEWNMTGQMQGWGDSPLVAEGIDGAKAVGEVLKDTPIDAVYTSTS
CCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHCCCCCEEEECCC
KRTQDTAAYILGDREIEIQPLEELKEMGFGTWEGIRVTEIDEQHPEERAKILHSPETYKA
CCCCCCEEEEECCCEEEECCHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHCCCCCCEEE
EVNGGETYYELAERLLEGVEKIIAENLSGNILVVSHGMSLTLLLYLLQGGTVEDHRKEAP
ECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCCCHHHHHCC
RILNTSISIVEYQNGEFSLKKINEIGHLDLK
HHHCCCEEEEEECCCCEEHHHHCCCCCCCCC
>Mature Secondary Structure 
AEGLRTIYFVRHGKTEWNMTGQMQGWGDSPLVAEGIDGAKAVGEVLKDTPIDAVYTSTS
CCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHCCCCCEEEECCC
KRTQDTAAYILGDREIEIQPLEELKEMGFGTWEGIRVTEIDEQHPEERAKILHSPETYKA
CCCCCCEEEEECCCEEEECCHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHCCCCCCEEE
EVNGGETYYELAERLLEGVEKIIAENLSGNILVVSHGMSLTLLLYLLQGGTVEDHRKEAP
ECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCCCHHHHHCC
RILNTSISIVEYQNGEFSLKKINEIGHLDLK
HHHCCCEEEEEECCCCEEHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA