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The map label for this gene is sorA [H]

Identifier: 226222735

GI number: 226222735

Start: 106237

End: 107043

Strand: Direct

Name: sorA [H]

Synonym: Lm4b_00100

Alternate gene names: 226222735

Gene position: 106237-107043 (Clockwise)

Preceding gene: 226222734

Following gene: 226222736

Centisome position: 3.65

GC content: 42.75

Gene sequence:

>807_bases
ATGTCTGTCATATCAATAATTTTAGTAGTACTTATTGCATTTTTAGCAGGTATTGAAGGAATTCTAGATGAATTTCAGTT
CCATCAGCCATTAATCGCATGTACATTAATTGGTCTCGTAACAGGTAACTTAACAGCATGTATCATCCTTGGCGGAACTC
TACAAATGATCGCACTTGGATGGGCAAACATCGGAGCAGCCGTAGCACCAGATGCCGCGCTTGCCTCAGTAGCTTCAGCA
ATTATATTAGTATTAGGTGGACAAGGGGTAGCAGGTATTCCATCTGCAATCGCGATTGCAATTCCACTAGCAGTAGCAGG
TCTTTTCTTAACAATGATCGTTCGTACATTGGCAGTTCCAATTGTTCACTTGATGGACAGAGCCGCTGAAAAAGGGAATA
TACGCAGCGTAGAGTGGTTACATATTTCAGCAATTTGTATGCAAGGTATTCGTATCGCGATTCCTGCAGCAGCACTTTTA
TTCATTCCAGCAGACAGCGTTCAATCTTTCTTAGAAGCAATGCCAGCTTGGTTAACAGATGGTATGGCTATCGGTGGAGG
AATGGTAGTTGCCGTTGGTTATGCACTAGTTATCAACATGATGGCTACTAAAGAAGTATGGCCGTTCTTCGTAATCGGTT
TCGTAGTAGCTGCAATTTCTCAACTTACACTTATCGCAATTGGTGCTCTAGGTGTTGCACTTGCTCTTATTTACCTTAAC
CTATCTAAAATGGGTGGCGGTAACTCAAACGGCGGTGGAGGCGGAAACTCTCGCGATCCACTGGGCGATATATTAAACGA
CTATTAA

Upstream 100 bases:

>100_bases
GTAAAGTCCCTAATGACTCAAGCGCAAACATGGAAGACATCATCAAAAAAGCAAAACACGAACTAAAGACACAATAAAAA
ATTAAAATAGGAGGTTTATT

Downstream 100 bases:

>100_bases
TAAAAAAAGGAGGAGAATAGAATGGCAGAAAAAATCGAATTATCAAAGAGAGACCGTCTACGCGTAGCATGGCGCTCTAC
GTTCATTCAAGGTTCATGGA

Product: PTS system mannose-specific, IIC component

Products: protein histidine; sugar phosphate; D-glucosamine-6-phosphate [Cytoplasm]; pyruvate; glucose-6-phosphate [Cytoplasm]; N-acetyl-D-glucosamine-6-phosphate [Cytoplasm]; mannose-6-phosphate [Cytoplasm]; fructose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Sor; PTS system sorbose-specific EIIC component [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MSVISIILVVLIAFLAGIEGILDEFQFHQPLIACTLIGLVTGNLTACIILGGTLQMIALGWANIGAAVAPDAALASVASA
IILVLGGQGVAGIPSAIAIAIPLAVAGLFLTMIVRTLAVPIVHLMDRAAEKGNIRSVEWLHISAICMQGIRIAIPAAALL
FIPADSVQSFLEAMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAAISQLTLIAIGALGVALALIYLN
LSKMGGGNSNGGGGGNSRDPLGDILNDY

Sequences:

>Translated_268_residues
MSVISIILVVLIAFLAGIEGILDEFQFHQPLIACTLIGLVTGNLTACIILGGTLQMIALGWANIGAAVAPDAALASVASA
IILVLGGQGVAGIPSAIAIAIPLAVAGLFLTMIVRTLAVPIVHLMDRAAEKGNIRSVEWLHISAICMQGIRIAIPAAALL
FIPADSVQSFLEAMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAAISQLTLIAIGALGVALALIYLN
LSKMGGGNSNGGGGGNSRDPLGDILNDY
>Mature_267_residues
SVISIILVVLIAFLAGIEGILDEFQFHQPLIACTLIGLVTGNLTACIILGGTLQMIALGWANIGAAVAPDAALASVASAI
ILVLGGQGVAGIPSAIAIAIPLAVAGLFLTMIVRTLAVPIVHLMDRAAEKGNIRSVEWLHISAICMQGIRIAIPAAALLF
IPADSVQSFLEAMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAAISQLTLIAIGALGVALALIYLNL
SKMGGGNSNGGGGGNSRDPLGDILNDY

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3715

COG function: function code G; Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-4 domain [H]

Homologues:

Organism=Escherichia coli, GI1788121, Length=266, Percent_Identity=47.3684210526316, Blast_Score=207, Evalue=8e-55,
Organism=Escherichia coli, GI1789528, Length=254, Percent_Identity=21.259842519685, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004700
- InterPro:   IPR018404 [H]

Pfam domain/function: PF03609 EII-Sor [H]

EC number: NA

Molecular weight: Translated: 27367; Mature: 27236

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS51106 PTS_EIIC_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVISIILVVLIAFLAGIEGILDEFQFHQPLIACTLIGLVTGNLTACIILGGTLQMIALG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCHHHHHHHH
WANIGAAVAPDAALASVASAIILVLGGQGVAGIPSAIAIAIPLAVAGLFLTMIVRTLAVP
HHHCCCHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVHLMDRAAEKGNIRSVEWLHISAICMQGIRIAIPAAALLFIPADSVQSFLEAMPAWLTD
HHHHHHHHHCCCCCCEEHHHHHHHHHHCCHHHHHHHHHHHEECHHHHHHHHHHHHHHHHC
GMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAAISQLTLIAIGALGVALALIYLN
CHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSKMGGGNSNGGGGGNSRDPLGDILNDY
HHHCCCCCCCCCCCCCCCCHHHHHHCCC
>Mature Secondary Structure 
SVISIILVVLIAFLAGIEGILDEFQFHQPLIACTLIGLVTGNLTACIILGGTLQMIALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCHHHHHHHH
WANIGAAVAPDAALASVASAIILVLGGQGVAGIPSAIAIAIPLAVAGLFLTMIVRTLAVP
HHHCCCHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVHLMDRAAEKGNIRSVEWLHISAICMQGIRIAIPAAALLFIPADSVQSFLEAMPAWLTD
HHHHHHHHHCCCCCCEEHHHHHHHHHHCCHHHHHHHHHHHEECHHHHHHHHHHHHHHHHC
GMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAAISQLTLIAIGALGVALALIYLN
CHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSKMGGGNSNGGGGGNSRDPLGDILNDY
HHHCCCCCCCCCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N p -phosphohistidine; sugar; phosphoenolpyruvate; glucosamine [Periplasm]; phosphoenolpyruvate; beta-D-glucose [Periplasm]; N-acetyl-D-glucosamine [Periplasm]; mannose [Periplasm]; fructose [Periplasm] [C]

Specific reaction: protein N p -phosphohistidine + sugar = protein histidine + sugar phosphate phosphoenolpyruvate + glucosamine [Periplasm] = D-glucosamine-6-phosphate [Cytoplasm] + pyruvate phosphoenolpyruvate + beta-D-glucose [Periplasm] = glucose-6-phosphate [Cytoplasm]

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7947968 [H]