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The map label for this gene is atpD1 [H]

Identifier: 226222730

GI number: 226222730

Start: 101887

End: 103257

Strand: Direct

Name: atpD1 [H]

Synonym: Lm4b_00095

Alternate gene names: 226222730

Gene position: 101887-103257 (Clockwise)

Preceding gene: 226222729

Following gene: 226222731

Centisome position: 3.5

GC content: 39.39

Gene sequence:

>1371_bases
ATGAAAAAAAACACAGGAACCATTATTAGTATTAGTGGTTTTGTTTTAAAAATCGAATTTAATGAGAGCGAACTGCCTGA
AATTGGCTTTGCGCTTGAGTATCATACACATCAAGGAACTTATCTAGCTGAAGTTGTTCAACATACTGGAATTAATACAG
TGTCTGCCATCGCTATTGGTGAGGTAAGTGGCTTGGCTAGAGGTACGGAAGTCGTTAATTTAGGACATCCAATTGAAGTA
CCTGTTGGGGAAACCGTCCAAGGAAGAATGCTAAATGTATATGGAAAAGCGATTGACGGCAAACCAGAACCAGCTGCGGA
AGTAAAATGGCCAATATTCCGTGACCAGCCTTTACTTCGAGAGCTAGATACGAATAAAGAAATTCTTTACACTGGTATTA
AAGTTATAGATCTTATTTGTCCTATTTTAAAAGGTGGGAAAACAGGTTTATTCGGTGGAGCGGGTGTAGGGAAATCTGTC
TTAATGCAAGAATTGATTAATAATATCAGTATGCTTGGTGGTAACTCTGTATTTACTGGGGTTGGAGAAAGAGTTAGAGA
GGGAATCGGCTTGTATAAAGAATTAGAAGCAAGTGGTGTGCTCCCTCAAACAACCGTTGTACTTGGTCAAATGAATGAAT
CTCCAGGTGTACGGATGCGCGTGGCATTAACAGGACTAACGATTGCAGAATATCTACGAGATGAAGAGAAAAAAGATGTT
TTATTATTTATAGATAATGTCTTCCGCTTTATTCAAGCGGGTTCTGAAGTTTCTTCTTTACAAGGAAAAATTCCTATTAC
TGGAGGTTACCAATCCACACTTTCCAAAGAGGTCGGCGATTTTCAAGACCGCATCGCGTCTACTAAAAATGGCTCTATTA
CCTCGATTCAGTGTGTATTTTTACCAGCAGATGATATTGATGATCCATCTGCAGTTGCGACGTTTAGCCATCTAGACTCA
ACAATTGTATTAGAGCGTTCGATTGCGGCACTTGGGATTTTCCCAGCGGTTAATCCACTTCAATCATTCTCAAGAGCACT
CAATCCAACCTTTGTTGGCGAGCGACACTACCAATTAGCGGCGCAAGTGAAATTTATCTTACAGCGTTATATGGAACTGC
AAGAAATCATCAACGTACTTGGAATGGCAGAATTAAGTGATGAAGATAGAAAACTAGTTCATCGTGCAAGGAAAATCAGG
AATTTCCTTTCACAACCATTCTATGTTTCGGAAAAATTCACTGGAACAGAAGGCACATTTGTAGAAATTGAAGATTTGCT
AGGGAGTATCGAACGCATTTTGAACGGTGATTATGATGAACGCTCAGAACGTGATTTCCTATTTATCGGATCCTACAAAG
ACTTGAAATAG

Upstream 100 bases:

>100_bases
AGCTATTTTTAATGCCAGAAAGCAAGCATTACAACAAAAAACTGGCGAATTACTCGATATCATTAGTGGAGCACAGACGA
TTAGGAAGGACGAAGAATAA

Downstream 100 bases:

>100_bases
GAGGAGAAGGAAATGAAACTTAAAATCGTCTCGCCTATGGGGCAGTTTTTTGAAGGAGAAGTAGAGGGCTTTGTTATTAA
TACAAAAGAAGGACAACAAA

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta 1; F-ATPase subunit beta 1 [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MKKNTGTIISISGFVLKIEFNESELPEIGFALEYHTHQGTYLAEVVQHTGINTVSAIAIGEVSGLARGTEVVNLGHPIEV
PVGETVQGRMLNVYGKAIDGKPEPAAEVKWPIFRDQPLLRELDTNKEILYTGIKVIDLICPILKGGKTGLFGGAGVGKSV
LMQELINNISMLGGNSVFTGVGERVREGIGLYKELEASGVLPQTTVVLGQMNESPGVRMRVALTGLTIAEYLRDEEKKDV
LLFIDNVFRFIQAGSEVSSLQGKIPITGGYQSTLSKEVGDFQDRIASTKNGSITSIQCVFLPADDIDDPSAVATFSHLDS
TIVLERSIAALGIFPAVNPLQSFSRALNPTFVGERHYQLAAQVKFILQRYMELQEIINVLGMAELSDEDRKLVHRARKIR
NFLSQPFYVSEKFTGTEGTFVEIEDLLGSIERILNGDYDERSERDFLFIGSYKDLK

Sequences:

>Translated_456_residues
MKKNTGTIISISGFVLKIEFNESELPEIGFALEYHTHQGTYLAEVVQHTGINTVSAIAIGEVSGLARGTEVVNLGHPIEV
PVGETVQGRMLNVYGKAIDGKPEPAAEVKWPIFRDQPLLRELDTNKEILYTGIKVIDLICPILKGGKTGLFGGAGVGKSV
LMQELINNISMLGGNSVFTGVGERVREGIGLYKELEASGVLPQTTVVLGQMNESPGVRMRVALTGLTIAEYLRDEEKKDV
LLFIDNVFRFIQAGSEVSSLQGKIPITGGYQSTLSKEVGDFQDRIASTKNGSITSIQCVFLPADDIDDPSAVATFSHLDS
TIVLERSIAALGIFPAVNPLQSFSRALNPTFVGERHYQLAAQVKFILQRYMELQEIINVLGMAELSDEDRKLVHRARKIR
NFLSQPFYVSEKFTGTEGTFVEIEDLLGSIERILNGDYDERSERDFLFIGSYKDLK
>Mature_456_residues
MKKNTGTIISISGFVLKIEFNESELPEIGFALEYHTHQGTYLAEVVQHTGINTVSAIAIGEVSGLARGTEVVNLGHPIEV
PVGETVQGRMLNVYGKAIDGKPEPAAEVKWPIFRDQPLLRELDTNKEILYTGIKVIDLICPILKGGKTGLFGGAGVGKSV
LMQELINNISMLGGNSVFTGVGERVREGIGLYKELEASGVLPQTTVVLGQMNESPGVRMRVALTGLTIAEYLRDEEKKDV
LLFIDNVFRFIQAGSEVSSLQGKIPITGGYQSTLSKEVGDFQDRIASTKNGSITSIQCVFLPADDIDDPSAVATFSHLDS
TIVLERSIAALGIFPAVNPLQSFSRALNPTFVGERHYQLAAQVKFILQRYMELQEIINVLGMAELSDEDRKLVHRARKIR
NFLSQPFYVSEKFTGTEGTFVEIEDLLGSIERILNGDYDERSERDFLFIGSYKDLK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [H]

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=457, Percent_Identity=51.4223194748359, Blast_Score=455, Evalue=1e-128,
Organism=Homo sapiens, GI19913424, Length=325, Percent_Identity=28.6153846153846, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI19913428, Length=386, Percent_Identity=24.3523316062176, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI19913426, Length=386, Percent_Identity=24.0932642487047, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI50345984, Length=393, Percent_Identity=22.9007633587786, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI4757810, Length=393, Percent_Identity=22.9007633587786, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1790170, Length=451, Percent_Identity=52.549889135255, Blast_Score=468, Evalue=1e-133,
Organism=Escherichia coli, GI1788251, Length=316, Percent_Identity=29.4303797468354, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1790172, Length=462, Percent_Identity=24.8917748917749, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=458, Percent_Identity=50.6550218340611, Blast_Score=442, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI17565854, Length=346, Percent_Identity=28.6127167630058, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17570191, Length=361, Percent_Identity=24.6537396121884, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17510931, Length=346, Percent_Identity=23.6994219653179, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71988080, Length=371, Percent_Identity=22.6415094339623, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71988063, Length=371, Percent_Identity=22.6415094339623, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71988074, Length=386, Percent_Identity=22.7979274611399, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322581, Length=457, Percent_Identity=52.9540481400438, Blast_Score=476, Evalue=1e-135,
Organism=Saccharomyces cerevisiae, GI6319603, Length=304, Percent_Identity=25.3289473684211, Blast_Score=93, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6320016, Length=260, Percent_Identity=26.5384615384615, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6319370, Length=353, Percent_Identity=22.9461756373938, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24638766, Length=457, Percent_Identity=50.7658643326039, Blast_Score=449, Evalue=1e-126,
Organism=Drosophila melanogaster, GI28574560, Length=462, Percent_Identity=51.9480519480519, Blast_Score=444, Evalue=1e-125,
Organism=Drosophila melanogaster, GI20129479, Length=328, Percent_Identity=28.6585365853659, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24583992, Length=325, Percent_Identity=28.3076923076923, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24583988, Length=330, Percent_Identity=29.0909090909091, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24583986, Length=330, Percent_Identity=29.0909090909091, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24583984, Length=330, Percent_Identity=29.0909090909091, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI281361666, Length=412, Percent_Identity=24.7572815533981, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24646341, Length=412, Percent_Identity=24.7572815533981, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17136796, Length=412, Percent_Identity=24.7572815533981, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24658560, Length=370, Percent_Identity=22.7027027027027, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24638768, Length=92, Percent_Identity=41.304347826087, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 50093; Mature: 50093

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNTGTIISISGFVLKIEFNESELPEIGFALEYHTHQGTYLAEVVQHTGINTVSAIAIG
CCCCCCCEEEEEEEEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCHHHHEEHH
EVSGLARGTEVVNLGHPIEVPVGETVQGRMLNVYGKAIDGKPEPAAEVKWPIFRDQPLLR
HHHHHCCCCEEEECCCCEECCCCCCCCCCEEEEECCCCCCCCCCCCCEECCCCCCCHHHH
ELDTNKEILYTGIKVIDLICPILKGGKTGLFGGAGVGKSVLMQELINNISMLGGNSVFTG
HCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHH
VGERVREGIGLYKELEASGVLPQTTVVLGQMNESPGVRMRVALTGLTIAEYLRDEEKKDV
HHHHHHHHHCHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEHHHHHHHHHCCCCCCCE
LLFIDNVFRFIQAGSEVSSLQGKIPITGGYQSTLSKEVGDFQDRIASTKNGSITSIQCVF
EEEHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEE
LPADDIDDPSAVATFSHLDSTIVLERSIAALGIFPAVNPLQSFSRALNPTFVGERHYQLA
ECCCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHH
AQVKFILQRYMELQEIINVLGMAELSDEDRKLVHRARKIRNFLSQPFYVSEKFTGTEGTF
HHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCE
VEIEDLLGSIERILNGDYDERSERDFLFIGSYKDLK
EEHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MKKNTGTIISISGFVLKIEFNESELPEIGFALEYHTHQGTYLAEVVQHTGINTVSAIAIG
CCCCCCCEEEEEEEEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCHHHHEEHH
EVSGLARGTEVVNLGHPIEVPVGETVQGRMLNVYGKAIDGKPEPAAEVKWPIFRDQPLLR
HHHHHCCCCEEEECCCCEECCCCCCCCCCEEEEECCCCCCCCCCCCCEECCCCCCCHHHH
ELDTNKEILYTGIKVIDLICPILKGGKTGLFGGAGVGKSVLMQELINNISMLGGNSVFTG
HCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHH
VGERVREGIGLYKELEASGVLPQTTVVLGQMNESPGVRMRVALTGLTIAEYLRDEEKKDV
HHHHHHHHHCHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEHHHHHHHHHCCCCCCCE
LLFIDNVFRFIQAGSEVSSLQGKIPITGGYQSTLSKEVGDFQDRIASTKNGSITSIQCVF
EEEHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEE
LPADDIDDPSAVATFSHLDSTIVLERSIAALGIFPAVNPLQSFSRALNPTFVGERHYQLA
ECCCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHH
AQVKFILQRYMELQEIINVLGMAELSDEDRKLVHRARKIRNFLSQPFYVSEKFTGTEGTF
HHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCE
VEIEDLLGSIERILNGDYDERSERDFLFIGSYKDLK
EEHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]