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The map label for this gene is cutC [C]

Identifier: 226222666

GI number: 226222666

Start: 30334

End: 30975

Strand: Direct

Name: cutC [C]

Synonym: Lm4b_00029

Alternate gene names: 226222666

Gene position: 30334-30975 (Clockwise)

Preceding gene: 226222665

Following gene: 226222667

Centisome position: 1.04

GC content: 39.72

Gene sequence:

>642_bases
ATGATTTTAAAAGAAGCCTGTATTGAAAATACAACTAATCTGGTGAACGTTATTGAAGCTGGAGCTAATCGAGTGGAGCT
TTGTGATAATCTAGCGGAGGGCGGAACTTCTGTAAGTTACGGGATTGCGAAACATGTGGTGAAAATTTGTCATGAACAAA
ATGTAAGTGTAATGGCAATGGTCCGTCCCCGAAAAGGCAATTTTGTTTATACAAAAGAAGAAATTTCAGTTATGATTGAT
GACATTTTGATGTATAAGAAAATAGCGGTTGATGGCGTGGTTTTTGGCTGTATTACGGATTCTGGATTGCTAGATAAACC
AGCCATAATTGAATTATTGAAAGCCACAGCAGGTCTGGAAGTCACTTTTCATATGGCGTTTGATGAGTTAGTAGACTCGG
AAAAATTGCCGGCAATTGACTGGTTAGCTGAGCAAGACGTTACAAGAATTCTCACGCATGGTGGTGACGGCGCTAAACTT
CCCGAAGAAACTTTTCTTCAATGGCGAAAATATATTGATTACGCAGCAGGTCGAATCATTATTTTACCAGGTGGAGGAAT
TAAATCGCACAATATGGAATGGATTACAAAAGAAACAGGAGCAGCTGAAATACATGGCACTGACTTGTTTGGGGAGCGCT
AA

Upstream 100 bases:

>100_bases
TTTTGCGATTGAAGACAAATTCGCTGATCGTATTTTCCACTTCTAATAAAAACGAGCGCGAAAATGAACATTATTTTCGC
GCTTTTTTGGAGGATAGAAA

Downstream 100 bases:

>100_bases
AACTCCCCAAATAAATTTATTTTAAAAAAAAGCTTGCAACCGTTTTCTTTATATGATATATTTATCTCATCACAAAGGAT
TGTTACCAATTCATTGGGCA

Product: copper homeostasis protein CutC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MILKEACIENTTNLVNVIEAGANRVELCDNLAEGGTSVSYGIAKHVVKICHEQNVSVMAMVRPRKGNFVYTKEEISVMID
DILMYKKIAVDGVVFGCITDSGLLDKPAIIELLKATAGLEVTFHMAFDELVDSEKLPAIDWLAEQDVTRILTHGGDGAKL
PEETFLQWRKYIDYAAGRIIILPGGGIKSHNMEWITKETGAAEIHGTDLFGER

Sequences:

>Translated_213_residues
MILKEACIENTTNLVNVIEAGANRVELCDNLAEGGTSVSYGIAKHVVKICHEQNVSVMAMVRPRKGNFVYTKEEISVMID
DILMYKKIAVDGVVFGCITDSGLLDKPAIIELLKATAGLEVTFHMAFDELVDSEKLPAIDWLAEQDVTRILTHGGDGAKL
PEETFLQWRKYIDYAAGRIIILPGGGIKSHNMEWITKETGAAEIHGTDLFGER
>Mature_213_residues
MILKEACIENTTNLVNVIEAGANRVELCDNLAEGGTSVSYGIAKHVVKICHEQNVSVMAMVRPRKGNFVYTKEEISVMID
DILMYKKIAVDGVVFGCITDSGLLDKPAIIELLKATAGLEVTFHMAFDELVDSEKLPAIDWLAEQDVTRILTHGGDGAKL
PEETFLQWRKYIDYAAGRIIILPGGGIKSHNMEWITKETGAAEIHGTDLFGER

Specific function: Involved In Copper Homeostasis. [C]

COG id: COG3142

COG function: function code P; Uncharacterized protein involved in copper resistance

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutC family [H]

Homologues:

Organism=Homo sapiens, GI148596990, Length=204, Percent_Identity=39.2156862745098, Blast_Score=145, Evalue=3e-35,
Organism=Escherichia coli, GI87081995, Length=209, Percent_Identity=29.1866028708134, Blast_Score=93, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17556905, Length=196, Percent_Identity=29.5918367346939, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355415, Length=212, Percent_Identity=31.1320754716981, Blast_Score=100, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005627 [H]

Pfam domain/function: PF03932 CutC [H]

EC number: NA

Molecular weight: Translated: 23435; Mature: 23435

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILKEACIENTTNLVNVIEAGANRVELCDNLAEGGTSVSYGIAKHVVKICHEQNVSVMAM
CCCHHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEE
VRPRKGNFVYTKEEISVMIDDILMYKKIAVDGVVFGCITDSGLLDKPAIIELLKATAGLE
EECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHCCCE
VTFHMAFDELVDSEKLPAIDWLAEQDVTRILTHGGDGAKLPEETFLQWRKYIDYAAGRII
EEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCEEE
ILPGGGIKSHNMEWITKETGAAEIHGTDLFGER
EECCCCCCCCCCEEEECCCCCCEEECCCCCCCC
>Mature Secondary Structure
MILKEACIENTTNLVNVIEAGANRVELCDNLAEGGTSVSYGIAKHVVKICHEQNVSVMAM
CCCHHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEE
VRPRKGNFVYTKEEISVMIDDILMYKKIAVDGVVFGCITDSGLLDKPAIIELLKATAGLE
EECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHCCCE
VTFHMAFDELVDSEKLPAIDWLAEQDVTRILTHGGDGAKLPEETFLQWRKYIDYAAGRII
EEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCEEE
ILPGGGIKSHNMEWITKETGAAEIHGTDLFGER
EECCCCCCCCCCEEEECCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA