Definition Streptococcus pneumoniae Taiwan19F-14, complete genome.
Accession NC_012469
Length 2,112,148

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The map label for this gene is fucA [H]

Identifier: 225861984

GI number: 225861984

Start: 2032527

End: 2033165

Strand: Reverse

Name: fucA [H]

Synonym: SPT_2179

Alternate gene names: 225861984

Gene position: 2033165-2032527 (Counterclockwise)

Preceding gene: 225861985

Following gene: 225861983

Centisome position: 96.26

GC content: 36.93

Gene sequence:

>639_bases
ATGTCAGATGTAAAACAAGAATTAATTAAGTATGGCAAGAAGCTAGTAGAAACAGATTTGACGAAAGGAACAGGTGGGAA
TCTCAGTGTTTTCGATCGTGAAAAACAATTGATGGCAATTACCCCGTCGGGTATTGATTTCTTTGAAATCAAAGAATCCG
ATATTGTAGTGATGGATATTAATGGAAATGTTGTAGAGGGAGAACGCTTGCCATCTAGCGAATGGTATATGCATTTGATT
CAATACCAAACTCGTGATGATATCGATGCAATTATCCATGCTCATACAACTTATGCAACAGTATTAGCTTGTCTCAGAGA
ACCACTTCCGGCTAGTCATTATATGATTGCAGTGGCAGGGAAAGATGTTCGGGTAGCTGAGTATGCAACATATGGTACGA
AAGAATTGGCTGTGAATGCAGCTAAAGCAATGGAAGGTCGTAGAGCAGTTTTACTAGCGAATCATGGAATTTTAGCAGGT
GCACAAAATTTATTGAATGCATTTAATATTGTTGAAGAAGTTGAATATTGTGCAAAAATTTATTGTTTAGCTAAGAATTT
TGGAGAGCCAGTAGTTCTTCCTGATGAGGAGATGGATTTAATGGCAGAAAAATTTAAAACATACGGTCAGAGAAAATAG

Upstream 100 bases:

>100_bases
TGTAAATTTGCCTCCCTCCCCCTTCTTAAGTTTTGTACAAGAAGGGGGGATAATTGGTGAATTGAAAAATATTTAGTGTT
TTGATATGAGGAGGACAAGA

Downstream 100 bases:

>100_bases
GGAGGATATTAATGTTAAAACATATACCGAAAAATATTTCTCCAGATTTATTGAAGACTTTAATGGAAATGGGACATGGA
GATGAAATAGTATTAGCTGA

Product: L-fuculose phosphate aldolase

Products: NA

Alternate protein names: L-fuculose-1-phosphate aldolase [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSGIDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLI
QYQTRDDIDAIIHAHTTYATVLACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK

Sequences:

>Translated_212_residues
MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSGIDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLI
QYQTRDDIDAIIHAHTTYATVLACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK
>Mature_211_residues
SDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSGIDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQ
YQTRDDIDAIIHAHTTYATVLACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAGA
QNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK

Specific function: Fucose metabolism; third step. [C]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789164, Length=212, Percent_Identity=41.9811320754717, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1790642, Length=111, Percent_Identity=38.7387387387387, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1786247, Length=229, Percent_Identity=28.82096069869, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1789094, Length=183, Percent_Identity=27.8688524590164, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1790008, Length=221, Percent_Identity=27.1493212669683, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR004782 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.1.2.17 [H]

Molecular weight: Translated: 23652; Mature: 23521

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSGIDFFEIKESDIVVMDI
CCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEECCCCCEEEEECCCCEEEEEC
NGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVLACLREPLPASHYMIAVAG
CCCEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEC
KDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAGAQNLLNAFNIVEEVEYCAKI
CCEEEEHHHHCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
YCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK
HHHHHCCCCCEEECCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSGIDFFEIKESDIVVMDI
CHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEECCCCCEEEEECCCCEEEEEC
NGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVLACLREPLPASHYMIAVAG
CCCEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEC
KDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAGAQNLLNAFNIVEEVEYCAKI
CCEEEEHHHHCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
YCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK
HHHHHCCCCCEEECCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]