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The map label for this gene is fucI [H]

Identifier: 225861976

GI number: 225861976

Start: 2022293

End: 2024059

Strand: Reverse

Name: fucI [H]

Synonym: SPT_2171

Alternate gene names: 225861976

Gene position: 2024059-2022293 (Counterclockwise)

Preceding gene: 225861977

Following gene: 225861975

Centisome position: 95.83

GC content: 42.44

Gene sequence:

>1767_bases
ATGATTCAACATCCACGTATTGGGATTCGTCCGACTATTGATGGTCGTCGTCAAGGTGTACGCGAATCACTTGAAGTGCA
AACAATGAACATGGCTAAAAGTGTGGCAGATTTGATTTCAAGCACATTGAAATATCCAGATGGGGAACCTGTGGAATGCG
TGATTTCTCCATCTACTATTGGCCGTGTACCAGAGGCTGCAGCTTCCCATGAGTTGTTTAAAAAATCAAATGTTTGCGCA
ACAATTACAGTTACACCATGCTGGTGTTATGGTAGTGAAACTATGGATATGTCTCCAGATATTCCTCATGCTATTTGGGG
ATTTAATGGGACAGAACGCCCAGGAGCTGTCTATCTTGCAGCTGTACTAGCTTCACATGCTCAAAAAGGGATTCCAGCCT
TTGGGATTTATGGTAGAGACGTCCAGGAAGCTAGTGATACAGCTATTCCAGAAGATGTCAAAGAAAAACTTTTACGTTAT
GCGCGTGCAGCTCTTGCAACTGGCTTGATGAGAGACACTGCTTACCTATCAATGGGTAGTGTTTCGATGGGGATTGGCGG
TTCTATTGTAAATCCGGATTTCTTCCAAGAATACTTAGGAATGCGAAATGAATCGGTAGATATGACGGAGTTCACGCGCC
GTATGGACCGTGGTATTTACGACCCTGAAGAGTTTGAACGTGCTATGGTTTGGGTAAAAGAACATATCAAAGAAGGAGTT
GACCGAAATCGTGAGGATTTGATTCTTTCTAAAGAAGAGAAAGAAAAACAATGGGAATTTGTTATTAAGATGTTCATGAT
TGGACGTGACTTAATGGTTGGTAACCCAAGACTTGCTGAACTTGGTTTTGAGGAAGAAGCAGTTGGTCACCATGCTTTAG
TAGCTGGTTTCCAAGGTCAACGTCAGTGGACAGACCATTTCCCAAATGGGGACTTTATGGAAACTTTCCTCAATACTCAG
TTTGACTGGAATGGTATTCGAAAACCATTTGTATTTGCGACAGAGAATGATTCACTAAATGGTGTGTCTATGCTCTTTAA
TTATCTATTAACAAATACTCCACAAATCTTTGCTGATGTGCGCACTTATTGGAGTCCAGAGGCTGTTAAACGTGTAACGG
GACATACTTTAGAGGGTTGTGCTGCAGCTGGCTTCTTACATCTAATCAACTCTGGTTCTTGTACATTGGATGGTACAGGG
CAAGCTACTCGAGATGGCAAACCTGTTATGAAACCCTTCTGGGAGTTGGATGAAAGTGAAGTGCAGGCTATGCTTGAAAA
TACAGACTTCCCACCAGCAAACCGCGAATACTTCCGTGGAGGAGGATTCTCAACTCGTTTCTTGACGAAGGGGGATATGC
CAGTAACAATGGTACGTCTCAATCTTCTAAAAGGGGTTGGTCCAGTGCTACAAATTGCAGAAGGTTATACACTTGAACTT
CCTGAAGATGTTCACCATACTTTAGATAATCGTACAGATCCAGGATGGCCAACTACTTGGTTTGCTCCACGTTTGACAGG
AAAAGGTGCTTTCAAGTCTGTCTATGACGTCATGAATAATTGGGGAGCTAATCACGGAGCCATAACATATGGCCACATTG
GAGCAGACTTGATTACCTTGGCTTCTATGTTGAGAATTCCTGTCAATATGCATAATGTACCCGAGGAAGATATCTTTAGA
CCTAAAAATTGGTCCTTATTTGGAACAGAAGATCTAGAATCAGCAGACTATCGTGCATGTCAGTTGTTGGGACCGCTACA
TAAATAA

Upstream 100 bases:

>100_bases
TTCCTTTAAGTTTGGCAGAGGTAGAGGTTTATACTTATAAGTAATTTTAAAAATTATCATCGGTAGTATGAAAGAAACAG
AAAAATAAGAGGAAAATAGT

Downstream 100 bases:

>100_bases
AAATTGTGTATATAGGAGGTGAACTTATGTCCCTCCTATCCTTTTAAAAAGATTTGTTAAACAATTCACAAATAATTGAA
AACGAATACAAAAACTAATA

Product: L-fucose isomerase

Products: NA

Alternate protein names: 6-deoxy-L-galactose isomerase; FucIase [H]

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLKYPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCA
TITVTPCWCYGSETMDMSPDIPHAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTAIPEDVKEKLLRY
ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRGIYDPEEFERAMVWVKEHIKEGV
DRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNPRLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQ
FDWNGIRKPFVFATENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGCAAAGFLHLINSGSCTLDGTG
QATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTKGDMPVTMVRLNLLKGVGPVLQIAEGYTLEL
PEDVHHTLDNRTDPGWPTTWFAPRLTGKGAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFR
PKNWSLFGTEDLESADYRACQLLGPLHK

Sequences:

>Translated_588_residues
MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLKYPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCA
TITVTPCWCYGSETMDMSPDIPHAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTAIPEDVKEKLLRY
ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRGIYDPEEFERAMVWVKEHIKEGV
DRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNPRLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQ
FDWNGIRKPFVFATENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGCAAAGFLHLINSGSCTLDGTG
QATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTKGDMPVTMVRLNLLKGVGPVLQIAEGYTLEL
PEDVHHTLDNRTDPGWPTTWFAPRLTGKGAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFR
PKNWSLFGTEDLESADYRACQLLGPLHK
>Mature_588_residues
MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLKYPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCA
TITVTPCWCYGSETMDMSPDIPHAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTAIPEDVKEKLLRY
ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRGIYDPEEFERAMVWVKEHIKEGV
DRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNPRLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQ
FDWNGIRKPFVFATENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGCAAAGFLHLINSGSCTLDGTG
QATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTKGDMPVTMVRLNLLKGVGPVLQIAEGYTLEL
PEDVHHTLDNRTDPGWPTTWFAPRLTGKGAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFR
PKNWSLFGTEDLESADYRACQLLGPLHK

Specific function: Converts the aldose L-fucose into the corresponding ketose L-fuculose [H]

COG id: COG2407

COG function: function code G; L-fucose isomerase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the L-fucose isomerase family [H]

Homologues:

Organism=Escherichia coli, GI1789167, Length=588, Percent_Identity=60.3741496598639, Blast_Score=740, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015888
- InterPro:   IPR004216
- InterPro:   IPR012888
- InterPro:   IPR005763
- InterPro:   IPR009015
- InterPro:   IPR012889 [H]

Pfam domain/function: PF02952 Fucose_iso_C; PF07881 Fucose_iso_N1; PF07882 Fucose_iso_N2 [H]

EC number: =5.3.1.25 [H]

Molecular weight: Translated: 65739; Mature: 65739

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLKYPDGEPVECVISPSTI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHH
GRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIPHAIWGFNGTERPGAVYLA
CCCCCHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCCCCCCCHHHCCCCCCCCCHHHHHH
AVLASHAQKGIPAFGIYGRDVQEASDTAIPEDVKEKLLRYARAALATGLMRDTAYLSMGS
HHHHHHHHCCCCEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
VSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRGIYDPEEFERAMVWVKEHIKEGV
EEECCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
DRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNPRLAELGFEEEAVGHHALVAGFQGQ
CCCCHHEEECCHHHHHHHHHHHHHHHHCCCEEECCCCHHHCCCCHHHCCCHHHEECCCCC
RQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFATENDSLNGVSMLFNYLLTNTPQIFADV
CHHHCCCCCCHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCHHHHHHH
RTYWSPEAVKRVTGHTLEGCAAAGFLHLINSGSCTLDGTGQATRDGKPVMKPFWELDESE
HHHCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHCCCHHH
VQAMLENTDFPPANREYFRGGGFSTRFLTKGDMPVTMVRLNLLKGVGPVLQIAEGYTLEL
HHHHHHCCCCCCCCCHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCHHHHHCCCCEEEC
PEDVHHTLDNRTDPGWPTTWFAPRLTGKGAFKSVYDVMNNWGANHGAITYGHIGADLITL
CHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHH
ASMLRIPVNMHNVPEEDIFRPKNWSLFGTEDLESADYRACQLLGPLHK
HHHHHCCCCCCCCCHHHCCCCCCCCEECCCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLKYPDGEPVECVISPSTI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHH
GRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIPHAIWGFNGTERPGAVYLA
CCCCCHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCCCCCCCHHHCCCCCCCCCHHHHHH
AVLASHAQKGIPAFGIYGRDVQEASDTAIPEDVKEKLLRYARAALATGLMRDTAYLSMGS
HHHHHHHHCCCCEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
VSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRGIYDPEEFERAMVWVKEHIKEGV
EEECCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
DRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNPRLAELGFEEEAVGHHALVAGFQGQ
CCCCHHEEECCHHHHHHHHHHHHHHHHCCCEEECCCCHHHCCCCHHHCCCHHHEECCCCC
RQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFATENDSLNGVSMLFNYLLTNTPQIFADV
CHHHCCCCCCHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCHHHHHHH
RTYWSPEAVKRVTGHTLEGCAAAGFLHLINSGSCTLDGTGQATRDGKPVMKPFWELDESE
HHHCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHCCCHHH
VQAMLENTDFPPANREYFRGGGFSTRFLTKGDMPVTMVRLNLLKGVGPVLQIAEGYTLEL
HHHHHHCCCCCCCCCHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCHHHHHCCCCEEEC
PEDVHHTLDNRTDPGWPTTWFAPRLTGKGAFKSVYDVMNNWGANHGAITYGHIGADLITL
CHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHH
ASMLRIPVNMHNVPEEDIFRPKNWSLFGTEDLESADYRACQLLGPLHK
HHHHHCCCCCCCCCHHHCCCCCCCCEECCCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA