Click here to switch to the map view.

The map label for this gene is ctpC [H]

Identifier: 225861917

GI number: 225861917

Start: 1961521

End: 1963584

Strand: Reverse

Name: ctpC [H]

Synonym: SPT_2110

Alternate gene names: 225861917

Gene position: 1963584-1961521 (Counterclockwise)

Preceding gene: 225861918

Following gene: 225861915

Centisome position: 92.97

GC content: 37.69

Gene sequence:

>2064_bases
ATGTCTTTTAAAGTGCTACATAGAGGATACCAACATATCCGACTATCATCTTCTTTTTCACTTACCTTGGATATTCAAGA
CTATCTTCGTTCCTTGGCGAGAGATGAAAAGGGGATTGAGTCTATCCAGTTTTACATGGATCAACAGCACTTTACTCTAC
GCATAAAAGAAGGCTTTTCTGTATTAGATAATGCAGAAGCCTTTTTAAAAAGAATTGATAAAGGGAAAGTTTCTGAGTTG
ATGACTCTTCCCATTCGTAGAGAAGAGAGTGCTTATTCTATTGTTTCAGGTGCAGCGGTTAAGCGTGTACTTTTTCGTAG
TTTTGTGCCGTATCCTATTCGCTATATATGGACTTGTTATCAGGCTTTGGGTTATATTAGAGAAGCCTATCAAACACTAG
CGCGTAAGGAACTAACGATGGAAGTCTTGGACTGTTCGGCTATTTTATTGTCTTTGTTTATGAACCAATCCAAGACAGCT
AGCAATATCATGTTTATGCTTGATTTGGGGAATCATTTAGATCAGTGGTCCTTGAAAAAAACTGCAACAGATTTAGAACA
GAGTCTTCTTGCAAAAGAGAGCGATGTATTCCTAGTACAGGGCGATACGGTTGTTAGTATCAAGAGTTCCGATGTTCAAA
TAGGAGATGTCTTGATCTTATCTCAAGGAAATGAAATTCTGTTTGATGGACAAGTAGTTTCAGGTTTAGGTATGGTCAAC
GAAAGTTCCTTGACAGGAGAGAGTTTTCCAGTTGAAAAAAGAGAGTCTGATTTGGTTTGTGCAAATACAGTATTAGAAAC
TGGAGAGTTACGCATTCGTGTAACAGATAATCAGATGAACAGCCGTATTTTACAGCTGATTAAGTTGATGAAGAAATCTG
AAGAAAACAAGAAAACGAAACAACGCTATTTCATCAAGATGGCGGATAAAGTCGTCAAATATAATTTCTTTGGGGCTGGG
CTGACTTACCTATTGACAGGTTCTTTTTCTAAAGCTATTTCTTTCCTATTGGTCGATTTCTCCTGCGCTTTGAAAATCTC
TACTCCTGTAGCTTATTTGACAGTTATCAAGGAAGGGTTGAACCGTGAAATGGTGATTAAGGATGGAGATGTTCTGGAGA
AATATCTGGAAGTTGATACTTTCTTGTTTGATAAGACAGGAACAATCACAACTAGTTATCCTATAGTTGAAAAGGTGTTA
CCTTTTGGAGACTATAGTGAGGAAGATATTCTCAGAATCAGTGCCTGTCTTGAGGAACACATTTATCATCCTATTGCTAA
TGCCATCGTCAAGCAAGCTGAGATAGAGGGAATTGAACATGAGGAAATGCATGGGAAACTCCAATATATCGCAAGCAAGG
GGATCAAATCTCATATAGATGGCCAACCAGTTCTTATTGGGAATTATGTCTTGATGCAGGATGAGCAGATTCATATCAGT
TCAGAACAAAATGCTTTAATTGAAGAGTACAAGAGTCACTACAATCTCTTATTCTTGGCTTATCAAAATGAATTGATTGG
AATGTTCTGCATTCATACTCCTTTGAGAAAAGAAGCAAAAACAGCCTTGGATAAACTTAAGGCACAGGGGAAAAAATTGA
TTCTGGCAACAGGAGACACCTTGATTAGGACAGAGGAATTAGTCAAAGATTTGCCCTTTGATCAGGTCTATACAGACTTG
AAACCTGATGGGAAATTTGAGTTAGTAGAGAAACTGCAGAAAGCAGGTCACACTATTTTGATGGTTGGAGATGGATTGAA
TGACTCAGCGGCTTTAACTCTATCAGATATCGGTGTGGTGATGAATGAGAGTGCAGATATTTCTAAGCAGATGAGTGATA
TCTTATTGTTAGATAATCGTTTGGATTTCTTCCAAGAGTTGGATTCGTTATCATCATCTTTGCAAACACTCATCAAGAAA
AATATTCAAGATACCGTTGTCGTAAATAGTAGTTTGATTGGCTTCGGCTTATTTAATTGGCTCAGTCCTTCAAATCTCTC
TATCTTACATAATCTAACAACCTTGCGCATTGTCCTGCGTAGCCTGTCTATTAAAAATAGATAG

Upstream 100 bases:

>100_bases
GTTGTGAAGCAACATGGAGACGATGTCTTGCAAGATGCCAAATATTTGTACGAGCAAGAGAAAAAAGAAGAGCAATTAGA
TAGCCTTATAGGTGAATAAT

Downstream 100 bases:

>100_bases
ATGAGAGTTATTAACAGCAAAAAGGAGTTACCTTTCTCGAGGTTAACTCCTTTGTTTATAGATAAATGTTGAATAGTTTA
GTAAGTCAATACAAAGTATT

Product: P-type ATPase-metal/cation transport

Products: ADP; phosphate; H+; K+

Alternate protein names: NA

Number of amino acids: Translated: 687; Mature: 686

Protein sequence:

>687_residues
MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQFYMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSEL
MTLPIRREESAYSIVSGAAVKRVLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVLILSQGNEILFDGQVVSGLGMVN
ESSLTGESFPVEKRESDLVCANTVLETGELRIRVTDNQMNSRILQLIKLMKKSEENKKTKQRYFIKMADKVVKYNFFGAG
LTYLLTGSFSKAISFLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTSYPIVEKVL
PFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYIASKGIKSHIDGQPVLIGNYVLMQDEQIHIS
SEQNALIEEYKSHYNLLFLAYQNELIGMFCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDL
KPDGKFELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFFQELDSLSSSLQTLIKK
NIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSLSIKNR

Sequences:

>Translated_687_residues
MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQFYMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSEL
MTLPIRREESAYSIVSGAAVKRVLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVLILSQGNEILFDGQVVSGLGMVN
ESSLTGESFPVEKRESDLVCANTVLETGELRIRVTDNQMNSRILQLIKLMKKSEENKKTKQRYFIKMADKVVKYNFFGAG
LTYLLTGSFSKAISFLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTSYPIVEKVL
PFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYIASKGIKSHIDGQPVLIGNYVLMQDEQIHIS
SEQNALIEEYKSHYNLLFLAYQNELIGMFCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDL
KPDGKFELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFFQELDSLSSSLQTLIKK
NIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSLSIKNR
>Mature_686_residues
SFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQFYMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELM
TLPIRREESAYSIVSGAAVKRVLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTAS
NIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVLILSQGNEILFDGQVVSGLGMVNE
SSLTGESFPVEKRESDLVCANTVLETGELRIRVTDNQMNSRILQLIKLMKKSEENKKTKQRYFIKMADKVVKYNFFGAGL
TYLLTGSFSKAISFLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTSYPIVEKVLP
FGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYIASKGIKSHIDGQPVLIGNYVLMQDEQIHISS
EQNALIEEYKSHYNLLFLAYQNELIGMFCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLK
PDGKFELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFFQELDSLSSSLQTLIKKN
IQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSLSIKNR

Specific function: Involved In Copper Efflux. [C]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily [H]

Homologues:

Organism=Homo sapiens, GI115529486, Length=629, Percent_Identity=24.483306836248, Blast_Score=177, Evalue=4e-44,
Organism=Homo sapiens, GI55743071, Length=661, Percent_Identity=24.2057488653555, Blast_Score=170, Evalue=5e-42,
Organism=Homo sapiens, GI55743073, Length=478, Percent_Identity=26.3598326359833, Blast_Score=167, Evalue=2e-41,
Organism=Escherichia coli, GI1786691, Length=506, Percent_Identity=26.8774703557312, Blast_Score=206, Evalue=4e-54,
Organism=Escherichia coli, GI1789879, Length=563, Percent_Identity=26.9982238010657, Blast_Score=185, Evalue=7e-48,
Organism=Escherichia coli, GI1786914, Length=448, Percent_Identity=20.7589285714286, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17556548, Length=548, Percent_Identity=25, Blast_Score=130, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320475, Length=446, Percent_Identity=26.6816143497758, Blast_Score=168, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6319772, Length=467, Percent_Identity=22.4839400428266, Blast_Score=107, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6325221, Length=513, Percent_Identity=19.8830409356725, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI221329854, Length=320, Percent_Identity=27.8125, Blast_Score=114, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: 3.6.3.10

Molecular weight: Translated: 77608; Mature: 77476

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00154 ATPASE_E1_E2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQFYMDQQHFTLRIKEGFS
CCCHHHHCCHHHEEECCCCEEEEEHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEEECCCC
VLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKRVLFRSFVPYPIRYIWTCY
HHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
QALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTASNIMFMLDLGNHLDQWSLKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHH
TATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVLILSQGNEILFDGQVVSGLGMVN
HHHHHHHHHHCCCCCEEEEECCEEEEEECCCEEEEEEEEEECCCEEEECCEEHHCCCCCC
ESSLTGESFPVEKRESDLVCANTVLETGELRIRVTDNQMNSRILQLIKLMKKSEENKKTK
CCCCCCCCCCCCCCCCCEEEHHHHEECCCEEEEEECCHHHHHHHHHHHHHHHCHHHHHHH
QRYFIKMADKVVKYNFFGAGLTYLLTGSFSKAISFLLVDFSCALKISTPVAYLTVIKEGL
HHHHHHHHHHHHHEEEECCCHHHHEECCHHHHHHHHHHHHEEEEEECCCHHHHHHHHHCC
NREMVIKDGDVLEKYLEVDTFLFDKTGTITTSYPIVEKVLPFGDYSEEDILRISACLEEH
CCEEEECCHHHHHHHHHHHHHEECCCCCEEECCHHHHHHCCCCCCCHHHHHHHHHHHHHH
IYHPIANAIVKQAEIEGIEHEEMHGKLQYIASKGIKSHIDGQPVLIGNYVLMQDEQIHIS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHCCCCCCEEEEEEEEEECCEEEEC
SEQNALIEEYKSHYNLLFLAYQNELIGMFCIHTPLRKEAKTALDKLKAQGKKLILATGDT
CCCHHHHHHHHCCCCEEEEEECCCCEEEHEECCCHHHHHHHHHHHHHHCCCEEEEECCCH
LIRTEELVKDLPFDQVYTDLKPDGKFELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVV
HHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCEEEEEHHCEE
MNESADISKQMSDILLLDNRLDFFQELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNW
ECCCCHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHC
LSPSNLSILHNLTTLRIVLRSLSIKNR
CCCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQFYMDQQHFTLRIKEGFS
CCHHHHCCHHHEEECCCCEEEEEHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEEECCCC
VLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKRVLFRSFVPYPIRYIWTCY
HHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
QALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTASNIMFMLDLGNHLDQWSLKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHH
TATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVLILSQGNEILFDGQVVSGLGMVN
HHHHHHHHHHCCCCCEEEEECCEEEEEECCCEEEEEEEEEECCCEEEECCEEHHCCCCCC
ESSLTGESFPVEKRESDLVCANTVLETGELRIRVTDNQMNSRILQLIKLMKKSEENKKTK
CCCCCCCCCCCCCCCCCEEEHHHHEECCCEEEEEECCHHHHHHHHHHHHHHHCHHHHHHH
QRYFIKMADKVVKYNFFGAGLTYLLTGSFSKAISFLLVDFSCALKISTPVAYLTVIKEGL
HHHHHHHHHHHHHEEEECCCHHHHEECCHHHHHHHHHHHHEEEEEECCCHHHHHHHHHCC
NREMVIKDGDVLEKYLEVDTFLFDKTGTITTSYPIVEKVLPFGDYSEEDILRISACLEEH
CCEEEECCHHHHHHHHHHHHHEECCCCCEEECCHHHHHHCCCCCCCHHHHHHHHHHHHHH
IYHPIANAIVKQAEIEGIEHEEMHGKLQYIASKGIKSHIDGQPVLIGNYVLMQDEQIHIS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHCCCCCCEEEEEEEEEECCEEEEC
SEQNALIEEYKSHYNLLFLAYQNELIGMFCIHTPLRKEAKTALDKLKAQGKKLILATGDT
CCCHHHHHHHHCCCCEEEEEECCCCEEEHEECCCHHHHHHHHHHHHHHCCCEEEEECCCH
LIRTEELVKDLPFDQVYTDLKPDGKFELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVV
HHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCEEEEEHHCEE
MNESADISKQMSDILLLDNRLDFFQELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNW
ECCCCHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHC
LSPSNLSILHNLTTLRIVLRSLSIKNR
CCCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+; K+

Specific reaction: ATP + H2O + H+(in) + K+(out) = ADP + phosphate + H+(out) + K+(in)

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]