Click here to switch to the map view.

The map label for this gene is nagA [H]

Identifier: 225861875

GI number: 225861875

Start: 1908817

End: 1909968

Strand: Reverse

Name: nagA [H]

Synonym: SPT_2051

Alternate gene names: 225861875

Gene position: 1909968-1908817 (Counterclockwise)

Preceding gene: 225861876

Following gene: 225861874

Centisome position: 90.43

GC content: 44.36

Gene sequence:

>1152_bases
ATGCCTAACTATATTAAAGCGGATCAGTTTTTCTACCCACACGGAGTTCGTCGAGGTGGTTACTTGGAACTTGTGGACGG
CAAGTTTGGGAAACATGTAGAGCAGATTTCTGAAGGGGCTGAGGTGATTGACTATACAGGTTATAGCATTGCCCCAGGTC
TTGTGGATACTCATATTCATGGATATGCAGGTGTAGATGTGATGGACAACAACATTGAAGGTACATTGCATACTATGAGT
GAAGGACTTCTTAGTACCGGTGTTACCAGTTTCTTACCCACAACTTTAACAGCCACTTATGAGCAATTGCTTGCAGTCAC
TGAAAATCTTGGAAACCATTATAAAGAAGCAACAGGTGCTAAGATTCGTGGGATTTATTATGAAGGTCCATATTTCACAG
AAACTTTTAAGGGGGCACAAAATCCAACTTATATGAGAGACCCGGGTGTTGAGGAGTTTCATTCTTGGCAAAAAGCGGCA
AATGGCTTGCTTAATAAAATTGCCCTTGCACCAGAACGTGATGGGGTGGAAGACTTTGTTCGTACAGTTACGGGCGAAGG
TGTGACGGTTGCTCTTGGACATTCAAACGCGACTTTTGCTGAAGCCAAAAAAGCAGTCGATGCTGGAGCGAGTGTTTGGG
TGCATGCCTACAATGGAATGCGTGGGTTGACTCACCGTGAATTGGGTATGGTTGGAGCCATGTACCAATTGCCACATACC
TATGCAGAGTTGATCTGTGATGGTCACCACGTAGATCCAAAGGCTTGCGAAATTCTTATCAAACAAAAAGGAACAGAAAA
CATCGCTCTTATCACAGACTGTATGACAGCTGGGGGATTGGAAGACGGAGATTATATGTTGGGAGAATTCCCAGTTGTCG
TTGCAAATGGAACTGCACGCCTCAAATCTACAGGTAACTTGGCAGGTTCTATCCTCAAACTCAAAGATGGTTTGAAGAAT
GTGGTCGAATGGGGAATTGCGAATCCGCATGAAGCAGTCATGATGGCCAGCTTCAACCCAGCTAAATCCGTTCACATCGA
TGACGTCTGTGGCCAAATCCGTGAAGGCTACGACGCTGACTTCATCGTATTAGATAAAGATTTGGAATTGGTAGCAACCT
ACCTAGATGGCGTAAAACGTTATCAAGCATAA

Upstream 100 bases:

>100_bases
CCAAAAAATAGGTCTATACCATTTACAAATAAAAAAGAAAGGTTTATAATGTAATTGACATAATAAATTGTAGAATCAAT
CTTTTAAGGAGGTTAACATT

Downstream 100 bases:

>100_bases
GAGAGAAAGCAGAAGTTAGAGACTAACTTCTGCTTTTTTATGCAGGGTACTTTACTGGTAAATAAAAAGTTAAAAAAATC
ACAAAAAAAGCTTGAAGAAA

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQISEGAEVIDYTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMS
EGLLSTGVTSFLPTTLTATYEQLLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFAEAKKAVDAGASVWVHAYNGMRGLTHRELGMVGAMYQLPHT
YAELICDGHHVDPKACEILIKQKGTENIALITDCMTAGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKN
VVEWGIANPHEAVMMASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA

Sequences:

>Translated_383_residues
MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQISEGAEVIDYTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMS
EGLLSTGVTSFLPTTLTATYEQLLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFAEAKKAVDAGASVWVHAYNGMRGLTHRELGMVGAMYQLPHT
YAELICDGHHVDPKACEILIKQKGTENIALITDCMTAGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKN
VVEWGIANPHEAVMMASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA
>Mature_382_residues
PNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQISEGAEVIDYTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSE
GLLSTGVTSFLPTTLTATYEQLLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAAN
GLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFAEAKKAVDAGASVWVHAYNGMRGLTHRELGMVGAMYQLPHTY
AELICDGHHVDPKACEILIKQKGTENIALITDCMTAGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNV
VEWGIANPHEAVMMASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=382, Percent_Identity=28.7958115183246, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI224922791, Length=376, Percent_Identity=28.7234042553192, Blast_Score=136, Evalue=3e-32,
Organism=Escherichia coli, GI1786892, Length=354, Percent_Identity=29.0960451977401, Blast_Score=139, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17553768, Length=356, Percent_Identity=27.247191011236, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI19920392, Length=346, Percent_Identity=32.3699421965318, Blast_Score=165, Evalue=6e-41,
Organism=Drosophila melanogaster, GI281361140, Length=359, Percent_Identity=31.4763231197772, Blast_Score=162, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41644; Mature: 41512

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQISEGAEVIDYTGYSIAPGLVDTHIH
CCCCCCCCCEECCCCCCCCCEEEEECCCHHHHHHHHHCCCCEEEECCCCCCCCCHHHCCC
GYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQLLAVTENLGNHYKEATGA
CEECCEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAANGLLNKIALAPERDGVEDFV
EEEEEEECCCEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
RTVTGEGVTVALGHSNATFAEAKKAVDAGASVWVHAYNGMRGLTHRELGMVGAMYQLPHT
HHHCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
YAELICDGHHVDPKACEILIKQKGTENIALITDCMTAGGLEDGDYMLGEFPVVVANGTAR
HHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEHHHHHCCCCCCCEEECCCCEEEECCCEE
LKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVMMASFNPAKSVHIDDVCGQIREGYDAD
ECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCC
FIVLDKDLELVATYLDGVKRYQA
EEEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQISEGAEVIDYTGYSIAPGLVDTHIH
CCCCCCCCEECCCCCCCCCEEEEECCCHHHHHHHHHCCCCEEEECCCCCCCCCHHHCCC
GYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQLLAVTENLGNHYKEATGA
CEECCEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAANGLLNKIALAPERDGVEDFV
EEEEEEECCCEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
RTVTGEGVTVALGHSNATFAEAKKAVDAGASVWVHAYNGMRGLTHRELGMVGAMYQLPHT
HHHCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
YAELICDGHHVDPKACEILIKQKGTENIALITDCMTAGGLEDGDYMLGEFPVVVANGTAR
HHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEHHHHHCCCCCCCEEECCCCEEEECCCEE
LKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVMMASFNPAKSVHIDDVCGQIREGYDAD
ECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCC
FIVLDKDLELVATYLDGVKRYQA
EEEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969210 [H]