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The map label for this gene is hit [H]

Identifier: 225858358

GI number: 225858358

Start: 528579

End: 528989

Strand: Reverse

Name: hit [H]

Synonym: SP70585_0578

Alternate gene names: 225858358

Gene position: 528989-528579 (Counterclockwise)

Preceding gene: 225858361

Following gene: 225858357

Centisome position: 24.21

GC content: 42.82

Gene sequence:

>411_bases
ATGTCAGATTGCATTTTTTGTAAAATCATCGCAGGGGAAATTCCTGCTTCAAAAGTATATGAAGATGAGCAGGTCCTTGC
CTTTCTTGATATCTCTCAAGTAACACTAGGACACACCTTGGTCGTGCCAAAAGAACACTATCGCAATCTTTTGGAGATGG
ATGCTACGAGCGCCAGCCAACTCTTTGCCCAAGTACCAAAAGTAGCTCAAAAAGTCATGAAAGTCACTAAGGCTGCTGGT
ATGAATATCATTTCCAACTGTGAAGAAGTCGCTGGTCAAACAGTTTTTCATACTCACGTTCACCTTGTGCCTCGCTACAG
TGCTGACGATGACCTCAAGATTGATTTTATCGCCCACGAACCAGACTTTGACAAACTTGCTCAAGTCGCTGAAACCATCA
AAAACGCTTAA

Upstream 100 bases:

>100_bases
ATAGCCACCTGTCAGGTTTTTAATTTCTAACATATTTTCTCCAAATCTGGTATAATGTAGCTATATTATATCAAAATTCA
GTACAGTAGAGGTAGATTTT

Downstream 100 bases:

>100_bases
GGAGTTGCTATGAAATTATCCAACCTACTGCTATTTGCAGGAGCTGCAGCCGGAAGTTATCTGGTTACAAAAAATCGCCA
AACCATCACAGATGAAGTCT

Product: histidine triad domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPKEHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAG
MNIISNCEEVAGQTVFHTHVHLVPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA

Sequences:

>Translated_136_residues
MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPKEHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAG
MNIISNCEEVAGQTVFHTHVHLVPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA
>Mature_135_residues
SDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPKEHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGM
NIISNCEEVAGQTVFHTHVHLVPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI17506713, Length=103, Percent_Identity=36.8932038834951, Blast_Score=65, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6320078, Length=126, Percent_Identity=35.7142857142857, Blast_Score=87, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 15056; Mature: 14925

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPKEHYRNLLEMDATSASQ
CCCCEEEEEECCCCCHHHHCCCCCEEEEECHHHHHCCCEEECCHHHHHHHHHHCCCHHHH
LFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHLVPRYSADDDLKIDFIAHE
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEHHEEEEECCCCCCCCEEEEEECC
PDFDKLAQVAETIKNA
CCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPKEHYRNLLEMDATSASQ
CCCEEEEEECCCCCHHHHCCCCCEEEEECHHHHHCCCEEECCHHHHHHHHHHCCCHHHH
LFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHLVPRYSADDDLKIDFIAHE
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEHHEEEEECCCCCCCCEEEEEECC
PDFDKLAQVAETIKNA
CCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]