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The map label for this gene is yecS [H]

Identifier: 225858303

GI number: 225858303

Start: 467881

End: 469446

Strand: Reverse

Name: yecS [H]

Synonym: SP70585_0523

Alternate gene names: 225858303

Gene position: 469446-467881 (Counterclockwise)

Preceding gene: 225858305

Following gene: 225858302

Centisome position: 21.49

GC content: 43.17

Gene sequence:

>1566_bases
ATGAGAAAAATATACTTATCTATTTTCACAAGTCTCTTGCTGATGCTAGGACTTGTCAATGTTGCTCAAGCCGATGAATA
TTTACGCATCGGGATGGAAGCAGCATATGCTCCCTTTAACTGGACCCAGGATGATGATAGCAACGGAGCTGTCAAAATCG
ATGGGACCAATCAGTATGCCAACGGATACGATGTTCAAATCGCCAAGAAAATCGCTAAGGACTTAGGTAAAGAACCTTTG
GTTGTTAAAACCAAGTGGGAAGGTCTAGTCCCTGCCCTTACTTCTGGTAAGATTGACATGATTATCGCAGGTATGAGTCC
AACTGCAGAACGCAAACAAGAAATTGCCTTTTCGAGCAGTTACTACACTAGCGAACCAGTTCTACTGGTCAAAAAAGATT
CTGCCTATGCAAGTGCTAAATCTTTGGATGACTTTAATGGTGCGAAAATCACTTCTCAACAAGGTGTCTACCTTTATGAC
TTGATTGCACAAATCACAGGTGCTAAAAAAGAAACAGCCATGGGAGACTTCGCTCAAATGCGCCAAGCTCTTGAGGCTGG
TGTCATCGACGCCTATGTTTCTGAACGCCCAGAAGCTCTGACTGCCGAAGCCGCTAACTCTAAGTTCAAGATGGTCCAAG
TAGAACCAGGTTTCAAAACTGGGGAAGAAGATACAGCTATCGCTATCGGGCTTCGTAAAAATGACAATCGTATTAGCCAA
ATCAATGCCAGCATTGAAACCATTTCAAAAGATGACCAAGTTGCCTTGATGGATCGTATGATCAAGGAACAACCTGCCGA
AGCTACAACAACTGAAGAGACTAGCAGTAGTTTCTTTAGCCAAGTCGCTAAAATTCTTTCTGAAAACTGGCAACAACTCT
TGCGTGGTGCTGGTATCACTCTTTTAATCTCTATCGTCGGAACCATCATAGGTCTCATTATTGGACTTGCCATTGGTGTC
TTCCGTACTGCTCCTCTCTCTGAAAACAAAGCCATTTATGGCCTTCAAAAACTAGTCGGCTGGGTTCTCAATGTCTACAT
TGAAATTTTCCGTGGTACGCCAATGATTGTTCAATCGATGGTTATCTACTATGGAACTGCCCAAGCTTTCGGGATCAACC
TTGACCGTACACTGGCTGCTATCTTCATCGTTTCAATCAATACCGGTGCCTACATGACTGAAATCGTCCGTGGTGGTATC
CTAGCAGTTGACAAGGGACAATTTGAAGCTGCGACTGCTCTTGGTATGACCCATAACCAGACCATGCGTAAGATTGTCCT
ACCTCAGGTAGTCCGTAACATCCTACCTGCAACTGGTAATGAATTTGTCATCAATATCAAAGATACATCTGTATTGAACG
TTATCTCTGTTGTCGAACTTTATTTCTCAGGAAATACCGTGGCAACACAAACCTATCAATACTTCCAGACATTTACAATC
ATCGCCGTGATTTACTTTGTCCTCACCTTCACCGTAACACGTATCCTACGCTTTATCGAGCGCAGAATGGACATGGATAC
CTACACTACAGGTGCTAACCAAATGCAAACGGAGGATTTGAAATAA

Upstream 100 bases:

>100_bases
CATTTTTTCGTAAGTAAAGGCTTACTTATGTTGAAAAATTACGCATTTTTCGATAAAATAGGAGACAGTTATTTTTTAAT
AGATCAGAATAGGAGAAATC

Downstream 100 bases:

>100_bases
TGACACAAGCAATCCTTGAAATTAAACACCTCAAAAAATCCTATGGACAAAACGAAGTGCTAAAAGACATTTCTCTCACT
GTCCACAAGGGAGAAGTTAT

Product: amino acid ABC transporter, amino acid-binding protein/permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQDDDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPL
VVKTKWEGLVPALTSGKIDMIIAGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
LIAQITGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMVQVEPGFKTGEEDTAIAIGLRKNDNRISQ
INASIETISKDDQVALMDRMIKEQPAEATTTEETSSSFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGV
FRTAPLSENKAIYGLQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYMTEIVRGGI
LAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTSVLNVISVVELYFSGNTVATQTYQYFQTFTI
IAVIYFVLTFTVTRILRFIERRMDMDTYTTGANQMQTEDLK

Sequences:

>Translated_521_residues
MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQDDDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPL
VVKTKWEGLVPALTSGKIDMIIAGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
LIAQITGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMVQVEPGFKTGEEDTAIAIGLRKNDNRISQ
INASIETISKDDQVALMDRMIKEQPAEATTTEETSSSFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGV
FRTAPLSENKAIYGLQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYMTEIVRGGI
LAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTSVLNVISVVELYFSGNTVATQTYQYFQTFTI
IAVIYFVLTFTVTRILRFIERRMDMDTYTTGANQMQTEDLK
>Mature_521_residues
MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQDDDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPL
VVKTKWEGLVPALTSGKIDMIIAGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
LIAQITGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMVQVEPGFKTGEEDTAIAIGLRKNDNRISQ
INASIETISKDDQVALMDRMIKEQPAEATTTEETSSSFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGV
FRTAPLSENKAIYGLQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYMTEIVRGGI
LAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTSVLNVISVVELYFSGNTVATQTYQYFQTFTI
IAVIYFVLTFTVTRILRFIERRMDMDTYTTGANQMQTEDLK

Specific function: Probably part of the binding-protein-dependent transport system yecCS for an amino acid; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=212, Percent_Identity=38.2075471698113, Blast_Score=155, Evalue=7e-39,
Organism=Escherichia coli, GI1787030, Length=218, Percent_Identity=39.4495412844037, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788646, Length=220, Percent_Identity=32.7272727272727, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787087, Length=233, Percent_Identity=28.3261802575107, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1786873, Length=218, Percent_Identity=27.9816513761468, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1788645, Length=238, Percent_Identity=31.9327731092437, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1787086, Length=224, Percent_Identity=28.125, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082239, Length=168, Percent_Identity=29.7619047619048, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786874, Length=223, Percent_Identity=26.0089686098655, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788228, Length=235, Percent_Identity=28.5106382978723, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI48994930, Length=136, Percent_Identity=32.3529411764706, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787088, Length=246, Percent_Identity=25.609756097561, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1787085, Length=193, Percent_Identity=24.8704663212435, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1787031, Length=212, Percent_Identity=26.4150943396226, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788648, Length=107, Percent_Identity=32.7102803738318, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1788649, Length=149, Percent_Identity=29.5302013422819, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 57350; Mature: 57350

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQDDDSNGAVKIDGTNQYA
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCC
NGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMIIAGMSPTAERKQEIAFSSS
CCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCC
YYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYDLIAQITGAKKETAMGDFAQM
CCCCCCEEEEECCCCHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHH
RQALEAGVIDAYVSERPEALTAEAANSKFKMVQVEPGFKTGEEDTAIAIGLRKNDNRISQ
HHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCHHHH
INASIETISKDDQVALMDRMIKEQPAEATTTEETSSSFFSQVAKILSENWQQLLRGAGIT
HHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYGLQKLVGWVLNVYIEIFRGTPMIVQSM
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VIYYGTAQAFGINLDRTLAAIFIVSINTGAYMTEIVRGGILAVDKGQFEAATALGMTHNQ
HHHEECHHHCCCCHHHHEEEEEEEEECCCHHHHHHHCCCEEEEECCCCHHHHHHCCCHHH
TMRKIVLPQVVRNILPATGNEFVINIKDTSVLNVISVVELYFSGNTVATQTYQYFQTFTI
HHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
IAVIYFVLTFTVTRILRFIERRMDMDTYTTGANQMQTEDLK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQDDDSNGAVKIDGTNQYA
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCC
NGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMIIAGMSPTAERKQEIAFSSS
CCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCC
YYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYDLIAQITGAKKETAMGDFAQM
CCCCCCEEEEECCCCHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHH
RQALEAGVIDAYVSERPEALTAEAANSKFKMVQVEPGFKTGEEDTAIAIGLRKNDNRISQ
HHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCHHHH
INASIETISKDDQVALMDRMIKEQPAEATTTEETSSSFFSQVAKILSENWQQLLRGAGIT
HHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYGLQKLVGWVLNVYIEIFRGTPMIVQSM
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VIYYGTAQAFGINLDRTLAAIFIVSINTGAYMTEIVRGGILAVDKGQFEAATALGMTHNQ
HHHEECHHHCCCCHHHHEEEEEEEEECCCHHHHHHHCCCEEEEECCCCHHHHHHCCCHHH
TMRKIVLPQVVRNILPATGNEFVINIKDTSVLNVISVVELYFSGNTVATQTYQYFQTFTI
HHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
IAVIYFVLTFTVTRILRFIERRMDMDTYTTGANQMQTEDLK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]