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The map label for this gene is yitU [H]

Identifier: 225858135

GI number: 225858135

Start: 304643

End: 305455

Strand: Reverse

Name: yitU [H]

Synonym: SP70585_0345

Alternate gene names: 225858135

Gene position: 305455-304643 (Counterclockwise)

Preceding gene: 225858142

Following gene: 225858134

Centisome position: 13.98

GC content: 40.84

Gene sequence:

>813_bases
ATGACGAAAAAAATTATTGCAGTTGACCTGGATGGAACCCTGCTCAACTCAGACAGTCAAATTTCTGACTTTACCAAAAG
AACCATCAAAAAAGTTGCTGAAAAAGGCCATCAGGTTATTATTACGACAGGTCGCCCTTACCGTATGTCAAAAGATTTTT
ACCGTGAACTGGGCTTAGACACTCCTATGATTAACTTCAACGGATCCCTTACTCATTTACCAGACCAAGTTTGGGATTTT
GAAAAGTGTTTGACTGTAGACAAAAAATATCTGCTAGATATGGTTCAACGTTCAGAGGACATTCAAGCCGATTTTATCGC
TGGAGAATATCGTAAAAAATTCTACATTACAAATCCCAATGAAGAAATTGCCAATCCCAAACTATTTGGTGTAGAAGCTT
TCCAGCCTGAAGATCAATTCCAGCCTGAATTGGTGACCAAGGACCCTAACTGTATCCTCTTGCAGACCAGAGCCAGTGAC
AAATATGCCTTGGCAAAAGAAATGAACGCCTTCTACCAGCATCAACTTTCTATCAATACCTGGGGAGGTCCGCTCAATAT
CCTTGAATGTACCCCAAAAGGTGTCAACAAGGCCTTTGCTTTGGACTACTTGCTCAAGATAATGAATCGTGACAAAAAAG
ATTTGATTGCCTTTGGAGATGAACACAATGATACCGAAATGCTCGCTTTTGCTGGGAAGGGTTATGCCATGAAAAATGCC
AATCCAGAGCTACTCCCTTATGCAGATGAGCAAATTTCCCTTACCAACGACCAAGATGGGGTTGCCAAAACCCTACAAGA
CTTATTCTTATAA

Upstream 100 bases:

>100_bases
AAATTAATCCAATTTCATTTTTTGTTTGGAATCTGCTTTTCTGCCTGCTTTCTGTTATAATAGAAGACATCTTATCTGAA
AACACACTAGAAAGGTCCAT

Downstream 100 bases:

>100_bases
CCTATACTGATACTCAATGAGAATCAAAGAGCAAACTAGGAAGCTAGCCGTAGGTTGCTCAAAGCACTGCTTTGAGGTTG
TAGATGAAGCTGACGTGGTT

Product: Cof family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTGRPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDF
EKCLTVDKKYLLDMVQRSEDIQADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAFGDEHNDTEMLAFAGKGYAMKNA
NPELLPYADEQISLTNDQDGVAKTLQDLFL

Sequences:

>Translated_270_residues
MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTGRPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDF
EKCLTVDKKYLLDMVQRSEDIQADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAFGDEHNDTEMLAFAGKGYAMKNA
NPELLPYADEQISLTNDQDGVAKTLQDLFL
>Mature_269_residues
TKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTGRPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFE
KCLTVDKKYLLDMVQRSEDIQADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASDK
YALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAFGDEHNDTEMLAFAGKGYAMKNAN
PELLPYADEQISLTNDQDGVAKTLQDLFL

Specific function: Unknown

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

Organism=Escherichia coli, GI2367265, Length=290, Percent_Identity=28.9655172413793, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI48994981, Length=273, Percent_Identity=30.03663003663, Blast_Score=91, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: NA

Molecular weight: Translated: 30777; Mature: 30646

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS01228 COF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTGRPYRMSKDFYRELGLD
CCCEEEEEECCCEEECCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHCCC
TPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQADFIAGEYRKKFYITNPN
CCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEECCCCCEEEEECCC
EEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASDKYALAKEMNAFYQHQLSINT
HHHCCCEEEEEECCCCCCCCCCCEECCCCCEEEEEECCCCCHHHHHHHHHHHHHEEEEEE
WGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAFGDEHNDTEMLAFAGKGYAMKNA
CCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHEEEECCCCCCCEEEEEECCCEEECCC
NPELLPYADEQISLTNDQDGVAKTLQDLFL
CCCEECCCCCEEEECCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTGRPYRMSKDFYRELGLD
CCEEEEEECCCEEECCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHCCC
TPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQADFIAGEYRKKFYITNPN
CCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEECCCCCEEEEECCC
EEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASDKYALAKEMNAFYQHQLSINT
HHHCCCEEEEEECCCCCCCCCCCEECCCCCEEEEEECCCCCHHHHHHHHHHHHHEEEEEE
WGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAFGDEHNDTEMLAFAGKGYAMKNA
CCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHEEEECCCCCCCEEEEEECCCEEECCC
NPELLPYADEQISLTNDQDGVAKTLQDLFL
CCCEECCCCCEEEECCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9025291; 9384377 [H]