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The map label for this gene is suhB [H]

Identifier: 225852345

GI number: 225852345

Start: 831602

End: 832429

Strand: Direct

Name: suhB [H]

Synonym: BMEA_A0871

Alternate gene names: 225852345

Gene position: 831602-832429 (Clockwise)

Preceding gene: 225852344

Following gene: 225852347

Centisome position: 39.12

GC content: 57.97

Gene sequence:

>828_bases
ATGCGCTTTGGTGATGGACAACTCGATTGGCTGGCGGATCTTCTGGCAGAAGCGGCAGCCAAAGAAATAATGCCGCGTTT
CCGCCATCTGGAAGTGGGTGACATCCGGCAGAAGACATCCCCTGCTGATCTGGTGACAGAGGCGGATATTAATGCGGAAC
GCTTCATCACCGCCCGGTTGAGGGAGCGGTTTCCCGATGCGTTGATCGTGGGCGAAGAAGCCTGTTCCGACAATCCGGGC
TTGCTTGCGGGCTTGGGAGAGGCCGATCTGGCATTCACCATCGATCCGGTCGACGGCACTTTCAATTTTGCTTCCGGGGT
GCCGCTTTTTGGCGTGATGCTGGCGGTGGTGTCAAAAGGCGAAACCGTTGCAGGCATTATTCATGATCCCGTCGATAAGG
ACTGGATCATGGCTGCGAAGGGAGCCGGGAGCCATATCCGCCGTGCTGATGGTACGACCCGCAATGTGCATGTCGCCGCG
CCTGCCGCCATAGGGCAGATGACGGGTTCTGTATCGTGGCAATATACGCCTGAGCCGATGCGCTCGCGCCTTGCGCGCAA
CCATACGAAATTTCTCTCGCAGATCGGTTATCGCTGTGCGGCACATGAATATCGCATCATCGCGACAGGTGGTGCGCATT
TTGCGGTCTATAACAAGCTGATGCCGTGGGATCATCTGCCCGGCGCCCTTATTCATCAGGAAGCGGGCGGCTATCTTGCC
CGTTGGGACGGGAGCAACTATCTGCCATCTCATACCGGCGGCGGACTTCTAATCGCGCCCAGCAGGGAAAGCTGGCAGGC
GATCCGAACCGCCCTCTGGGAAGAATGA

Upstream 100 bases:

>100_bases
ATGATCCGCGCCCTGACCAATGTGCGGCCGAGCCATCTTCTGGATCGCAAACTGTTCGATTTTGCGGGCCTGATGGCCAA
TGGCGAGAAGGGTAGTGACG

Downstream 100 bases:

>100_bases
TACGAATGTAAAAGCCCGCCGGTCAGGCGGGCTCAGATTGATGAAAAACCCCTCGATTTTTGGCAGCAGTCAAAAACGAT
GGGTTTTGATTCCGATCTGC

Product: inositol monophosphatase family protein

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MRFGDGQLDWLADLLAEAAAKEIMPRFRHLEVGDIRQKTSPADLVTEADINAERFITARLRERFPDALIVGEEACSDNPG
LLAGLGEADLAFTIDPVDGTFNFASGVPLFGVMLAVVSKGETVAGIIHDPVDKDWIMAAKGAGSHIRRADGTTRNVHVAA
PAAIGQMTGSVSWQYTPEPMRSRLARNHTKFLSQIGYRCAAHEYRIIATGGAHFAVYNKLMPWDHLPGALIHQEAGGYLA
RWDGSNYLPSHTGGGLLIAPSRESWQAIRTALWEE

Sequences:

>Translated_275_residues
MRFGDGQLDWLADLLAEAAAKEIMPRFRHLEVGDIRQKTSPADLVTEADINAERFITARLRERFPDALIVGEEACSDNPG
LLAGLGEADLAFTIDPVDGTFNFASGVPLFGVMLAVVSKGETVAGIIHDPVDKDWIMAAKGAGSHIRRADGTTRNVHVAA
PAAIGQMTGSVSWQYTPEPMRSRLARNHTKFLSQIGYRCAAHEYRIIATGGAHFAVYNKLMPWDHLPGALIHQEAGGYLA
RWDGSNYLPSHTGGGLLIAPSRESWQAIRTALWEE
>Mature_275_residues
MRFGDGQLDWLADLLAEAAAKEIMPRFRHLEVGDIRQKTSPADLVTEADINAERFITARLRERFPDALIVGEEACSDNPG
LLAGLGEADLAFTIDPVDGTFNFASGVPLFGVMLAVVSKGETVAGIIHDPVDKDWIMAAKGAGSHIRRADGTTRNVHVAA
PAAIGQMTGSVSWQYTPEPMRSRLARNHTKFLSQIGYRCAAHEYRIIATGGAHFAVYNKLMPWDHLPGALIHQEAGGYLA
RWDGSNYLPSHTGGGLLIAPSRESWQAIRTALWEE

Specific function: Displays a 20-fold higher rate of hydrolysis of the D isoform of inositol 1-phosphate than of the L isoform [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI221625487, Length=226, Percent_Identity=26.1061946902655, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI5031789, Length=226, Percent_Identity=26.1061946902655, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI1788882, Length=236, Percent_Identity=29.2372881355932, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI193202572, Length=232, Percent_Identity=26.2931034482759, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21357957, Length=229, Percent_Identity=25.764192139738, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24664922, Length=208, Percent_Identity=31.25, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357329, Length=211, Percent_Identity=25.5924170616114, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24664926, Length=214, Percent_Identity=27.1028037383178, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24664918, Length=203, Percent_Identity=24.6305418719212, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 29956; Mature: 29956

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00629 IMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFGDGQLDWLADLLAEAAAKEIMPRFRHLEVGDIRQKTSPADLVTEADINAERFITARL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHEEECCCCHHHHHHHHH
RERFPDALIVGEEACSDNPGLLAGLGEADLAFTIDPVDGTFNFASGVPLFGVMLAVVSKG
HHHCCCEEEECHHHCCCCCCEEEECCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCC
ETVAGIIHDPVDKDWIMAAKGAGSHIRRADGTTRNVHVAAPAAIGQMTGSVSWQYTPEPM
CEEEEEECCCCCCCEEEEECCCCCHHECCCCCCCEEEEECCHHHHHHCCCEEEEECCHHH
RSRLARNHTKFLSQIGYRCAAHEYRIIATGGAHFAVYNKLMPWDHLPGALIHQEAGGYLA
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEHHHHCCCCCCCCCHHEECCCCCEEE
RWDGSNYLPSHTGGGLLIAPSRESWQAIRTALWEE
EECCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCC
>Mature Secondary Structure
MRFGDGQLDWLADLLAEAAAKEIMPRFRHLEVGDIRQKTSPADLVTEADINAERFITARL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHEEECCCCHHHHHHHHH
RERFPDALIVGEEACSDNPGLLAGLGEADLAFTIDPVDGTFNFASGVPLFGVMLAVVSKG
HHHCCCEEEECHHHCCCCCCEEEECCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCC
ETVAGIIHDPVDKDWIMAAKGAGSHIRRADGTTRNVHVAAPAAIGQMTGSVSWQYTPEPM
CEEEEEECCCCCCCEEEEECCCCCHHECCCCCCCEEEEECCHHHHHHCCCEEEEECCHHH
RSRLARNHTKFLSQIGYRCAAHEYRIIATGGAHFAVYNKLMPWDHLPGALIHQEAGGYLA
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEHHHHCCCCCCCCCHHEECCCCCEEE
RWDGSNYLPSHTGGGLLIAPSRESWQAIRTALWEE
EECCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9720201; 10360571; 10508089 [H]