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The map label for this gene is speB [H]

Identifier: 225852303

GI number: 225852303

Start: 791404

End: 792354

Strand: Reverse

Name: speB [H]

Synonym: BMEA_A0827

Alternate gene names: 225852303

Gene position: 792354-791404 (Counterclockwise)

Preceding gene: 225852304

Following gene: 225852302

Centisome position: 37.27

GC content: 59.2

Gene sequence:

>951_bases
ATGCCTTCAAAGACCATCGACCATGCGATCACTGCCCGCAGCCTGACCAGTGCGGCCACCGACCCAACCCATGCGGGCGT
CTTGTCCTTCATGCGGCGCACTTACTCCAAGTCGCTCAAAGGCGCGGAAGCAGTTGTCTGGGGCATTCCTTTCGATGCCG
CCGTTTCCAACCGGCCCGGCGCACGCTTCGGCCCGCAGGCGATCCGGCGCGCCTCGGCGATCTTCGACAACGATCCGCAA
TATCCGTTCGAGCGTGATCTTTTCGAGAATCTCGCTGTCATCGATTATGGCGACTGCCTGCTCAACTATGGCAATCACAC
CAAGACACCCTCCACCATCGAGCGTGAAGCAGCAAAAATCCTGAAATCCGATGCATTTCTGCTGACGCTCGGCGGCGATC
ATTTCATCACATGGCCGCTTCTCAAGGCCCATGCCGCAAAATACGGCCCCCTCGCTCTGGTGCAGTTCGATGCGCATCAG
GATACATGGTTCGATGATGGCAGGCGGATCGACCACGGCTCCTTCGTGGCCCGCACGGCGCGCGACGGCATCATCGATCC
CGACCTTTCGATCCAGATTGGCATCCGCACGCATGCGCCGGAAGATTGCGGCATCAGGATCATTTATGGCCACGAGGTCG
AGGATATGCCAGCGGCGGCGATTGCCGATGCAATCCTGAAACGCACCAATGGCAGGAAAGCCTATCTGACCTTCGACATT
GACTGTCTTGATCCGGCTTTTGCGCCGGGAACCGGCACGCCGGTTGCAGGCGGCCCCTCCTCGGCAAAGATGCTGTCTGT
CCTGCGCAAGCTGACGGCTCTTGACTTCGTGGGCGCCGATGTAGTCGAGGTTGCACCGGCCTATGACCATGCCGATATAA
CAGCCATCGCGGGAGCGACGATCGCAATGTATTATCTGGGCCTTCTGGGCGAACGGAAAGAACGACGATGA

Upstream 100 bases:

>100_bases
GAAGCGTTAATCCTTATCGCTTTGGACTTACAGAAAAGCGGGCCTTCGGGTCCGCTTTTTTGCTATGTAATAGGAGACTC
AAGCCAGCACGGAAGCGGCC

Downstream 100 bases:

>100_bases
AGCGTCGCGCTTGTTCATAGATTGATTCAAGCGGCTCGAAAACTGATTCCGAATATCGCCGTAACTTTCTGAATTCAAAG
GCAAAACGCATGAAACCGAA

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MPSKTIDHAITARSLTSAATDPTHAGVLSFMRRTYSKSLKGAEAVVWGIPFDAAVSNRPGARFGPQAIRRASAIFDNDPQ
YPFERDLFENLAVIDYGDCLLNYGNHTKTPSTIEREAAKILKSDAFLLTLGGDHFITWPLLKAHAAKYGPLALVQFDAHQ
DTWFDDGRRIDHGSFVARTARDGIIDPDLSIQIGIRTHAPEDCGIRIIYGHEVEDMPAAAIADAILKRTNGRKAYLTFDI
DCLDPAFAPGTGTPVAGGPSSAKMLSVLRKLTALDFVGADVVEVAPAYDHADITAIAGATIAMYYLGLLGERKERR

Sequences:

>Translated_316_residues
MPSKTIDHAITARSLTSAATDPTHAGVLSFMRRTYSKSLKGAEAVVWGIPFDAAVSNRPGARFGPQAIRRASAIFDNDPQ
YPFERDLFENLAVIDYGDCLLNYGNHTKTPSTIEREAAKILKSDAFLLTLGGDHFITWPLLKAHAAKYGPLALVQFDAHQ
DTWFDDGRRIDHGSFVARTARDGIIDPDLSIQIGIRTHAPEDCGIRIIYGHEVEDMPAAAIADAILKRTNGRKAYLTFDI
DCLDPAFAPGTGTPVAGGPSSAKMLSVLRKLTALDFVGADVVEVAPAYDHADITAIAGATIAMYYLGLLGERKERR
>Mature_315_residues
PSKTIDHAITARSLTSAATDPTHAGVLSFMRRTYSKSLKGAEAVVWGIPFDAAVSNRPGARFGPQAIRRASAIFDNDPQY
PFERDLFENLAVIDYGDCLLNYGNHTKTPSTIEREAAKILKSDAFLLTLGGDHFITWPLLKAHAAKYGPLALVQFDAHQD
TWFDDGRRIDHGSFVARTARDGIIDPDLSIQIGIRTHAPEDCGIRIIYGHEVEDMPAAAIADAILKRTNGRKAYLTFDID
CLDPAFAPGTGTPVAGGPSSAKMLSVLRKLTALDFVGADVVEVAPAYDHADITAIAGATIAMYYLGLLGERKERR

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=294, Percent_Identity=36.0544217687075, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI10947139, Length=282, Percent_Identity=26.5957446808511, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1789306, Length=253, Percent_Identity=43.8735177865613, Blast_Score=216, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 34297; Mature: 34166

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSKTIDHAITARSLTSAATDPTHAGVLSFMRRTYSKSLKGAEAVVWGIPFDAAVSNRPG
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHCCCCCC
ARFGPQAIRRASAIFDNDPQYPFERDLFENLAVIDYGDCLLNYGNHTKTPSTIEREAAKI
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCEEEECHHHHCCCCCCCCCHHHHHHHHHH
LKSDAFLLTLGGDHFITWPLLKAHAAKYGPLALVQFDAHQDTWFDDGRRIDHGSFVARTA
HHCCCEEEEECCCCEEEHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEECCCHHHHHHH
RDGIIDPDLSIQIGIRTHAPEDCGIRIIYGHEVEDMPAAAIADAILKRTNGRKAYLTFDI
CCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEEE
DCLDPAFAPGTGTPVAGGPSSAKMLSVLRKLTALDFVGADVVEVAPAYDHADITAIAGAT
EECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHH
IAMYYLGLLGERKERR
HHHHHHHHHCCHHCCC
>Mature Secondary Structure 
PSKTIDHAITARSLTSAATDPTHAGVLSFMRRTYSKSLKGAEAVVWGIPFDAAVSNRPG
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHCCCCCC
ARFGPQAIRRASAIFDNDPQYPFERDLFENLAVIDYGDCLLNYGNHTKTPSTIEREAAKI
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCEEEECHHHHCCCCCCCCCHHHHHHHHHH
LKSDAFLLTLGGDHFITWPLLKAHAAKYGPLALVQFDAHQDTWFDDGRRIDHGSFVARTA
HHCCCEEEEECCCCEEEHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEECCCHHHHHHH
RDGIIDPDLSIQIGIRTHAPEDCGIRIIYGHEVEDMPAAAIADAILKRTNGRKAYLTFDI
CCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEEE
DCLDPAFAPGTGTPVAGGPSSAKMLSVLRKLTALDFVGADVVEVAPAYDHADITAIAGAT
EECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHH
IAMYYLGLLGERKERR
HHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]