BacMap

Definition	Brucella melitensis ATCC 23457 chromosome chromosome I, complete sequence.
Accession	NC_012441
Length	2,125,701

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The map label for this gene is fabG [H]

Identifier: 225852237

GI number: 225852237

Start: 721582

End: 722286

Strand: Reverse

Name: fabG [H]

Synonym: BMEA_A0754

Alternate gene names: 225852237

Gene position: 722286-721582 (Counterclockwise)

Preceding gene: 225852238

Following gene: 225852236

Centisome position: 33.98

GC content: 58.3

Gene sequence:

>705_bases
ATGACAATTCAGAAAGTCGCGATCATAACAGCAGGGGGCAGCGGCATGGGAGCAGCCTCGGCCCGCCGTCTGGCACAGGA
CGGTTTTGCAGTTGCCATTCTGTCATCGTCCGGCAAGGGCGAAGCCCTCGCCAAAGAATTGGGGGGCATTGGCGTTACCG
GCTCGAACCAGTCCAACGACGACCTGCAAAAGCTGGTCGACCAGACTTTGGAAAAATGGGGGCGGATCGACGTTCTGGTC
AACAGCGCCGGTCATGGGCCGCGCGCACCAATTCTCGAAATTACCGACGAAGACTGGCATAAGGGAATGGACACCTATTT
CCTCAATGCCGTGCGCCCCGCGCGCCTCGTCGTGCCTGCAATGCAGAAGCAGAAATCGGGCGTCATCATCAATATTTCGA
CCGCCTGGGCTTTCGAGCCAAGTGCGATGTTCCCGACATCGGCTGTGTTCCGTGCAGGGCTTGCCTCCTTCACCAAAATA
TTTGCCGACACCTATGCGGCTGAGAATATCCGCATGAACAATGTCCTCCCCGGCTGGATCGACAGCCTGCCAACAACGGA
AGAACGCCGCGAAAGCGTGCCGATGCAGCGTTATGGGAAGAGCGAGGAAATCGCGGCAACCGTGTCGTTCCTTGCTTCCG
ATGGGGCGGCTTATATCACCGGGCAGAACCTGCGTGTCGATGGCGGCCTGACACGCTCAGTCTGA

Upstream 100 bases:

>100_bases
CAAGGCTGGCAAAATCTTATCTTCAACAAAATTGACTTGGGCTTTCAGGGCGATCCGCTAACTTTATCACATCAAACCAT
TGGGAACAGGGCCTGGAAGC

Downstream 100 bases:

>100_bases
ACGTTCCGGTAACGAAATGCGAAGGAAGACGCGGTAGTGTCTTCCTGTCGCGATTCGGACAGGAAACAGACAATGGCTGC
AAGGAAACGAAGCTCCTCTT

Product: oxidoreductase, short-chain dehydrogenase/reductase family protein

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MTIQKVAIITAGGSGMGAASARRLAQDGFAVAILSSSGKGEALAKELGGIGVTGSNQSNDDLQKLVDQTLEKWGRIDVLV
NSAGHGPRAPILEITDEDWHKGMDTYFLNAVRPARLVVPAMQKQKSGVIINISTAWAFEPSAMFPTSAVFRAGLASFTKI
FADTYAAENIRMNNVLPGWIDSLPTTEERRESVPMQRYGKSEEIAATVSFLASDGAAYITGQNLRVDGGLTRSV

Sequences:

>Translated_234_residues
MTIQKVAIITAGGSGMGAASARRLAQDGFAVAILSSSGKGEALAKELGGIGVTGSNQSNDDLQKLVDQTLEKWGRIDVLV
NSAGHGPRAPILEITDEDWHKGMDTYFLNAVRPARLVVPAMQKQKSGVIINISTAWAFEPSAMFPTSAVFRAGLASFTKI
FADTYAAENIRMNNVLPGWIDSLPTTEERRESVPMQRYGKSEEIAATVSFLASDGAAYITGQNLRVDGGLTRSV
>Mature_233_residues
TIQKVAIITAGGSGMGAASARRLAQDGFAVAILSSSGKGEALAKELGGIGVTGSNQSNDDLQKLVDQTLEKWGRIDVLVN
SAGHGPRAPILEITDEDWHKGMDTYFLNAVRPARLVVPAMQKQKSGVIINISTAWAFEPSAMFPTSAVFRAGLASFTKIF
ADTYAAENIRMNNVLPGWIDSLPTTEERRESVPMQRYGKSEEIAATVSFLASDGAAYITGQNLRVDGGLTRSV

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=36.1788617886179, Blast_Score=125, Evalue=3e-29,
Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=33.4677419354839, Blast_Score=104, Evalue=6e-23,
Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=30.4, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI40254992, Length=235, Percent_Identity=27.6595744680851, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI126723750, Length=246, Percent_Identity=30.0813008130081, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI10190704, Length=245, Percent_Identity=28.9795918367347, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI66933014, Length=182, Percent_Identity=30.7692307692308, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI126723191, Length=180, Percent_Identity=34.4444444444444, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=33.5106382978723, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=29.8804780876494, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI59889578, Length=205, Percent_Identity=28.780487804878, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4758504, Length=249, Percent_Identity=30.1204819277108, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1787335, Length=236, Percent_Identity=32.6271186440678, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI87082160, Length=243, Percent_Identity=29.6296296296296, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=34.6774193548387, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87082100, Length=248, Percent_Identity=29.4354838709677, Blast_Score=94, Evalue=5e-21,
Organism=Escherichia coli, GI1789208, Length=243, Percent_Identity=26.3374485596708, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787905, Length=239, Percent_Identity=28.8702928870293, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=28.2258064516129, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI2367365, Length=234, Percent_Identity=27.7777777777778, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1789378, Length=244, Percent_Identity=26.6393442622951, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1790717, Length=245, Percent_Identity=23.265306122449, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=246, Percent_Identity=33.739837398374, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17560676, Length=242, Percent_Identity=28.099173553719, Blast_Score=107, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=30.952380952381, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=258, Percent_Identity=31.3953488372093, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=28.4, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=34.8, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI25147288, Length=241, Percent_Identity=30.2904564315353, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17560332, Length=258, Percent_Identity=30.6201550387597, Blast_Score=87, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17538182, Length=246, Percent_Identity=28.0487804878049, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=258, Percent_Identity=29.4573643410853, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=25.3787878787879, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=28.735632183908, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=29.9242424242424, Blast_Score=77, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=259, Percent_Identity=29.7297297297297, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=273, Percent_Identity=29.6703296703297, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=257, Percent_Identity=28.7937743190661, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17508651, Length=248, Percent_Identity=28.6290322580645, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=28.4090909090909, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=257, Percent_Identity=26.8482490272374, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=29.5454545454545, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=29.5880149812734, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=27.9245283018868, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=27.8884462151394, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=27.6515151515151, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=255, Percent_Identity=27.4509803921569, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=27.6515151515151, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=250, Percent_Identity=27.6, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=191, Percent_Identity=26.1780104712042, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=180, Percent_Identity=24.4444444444444, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355319, Length=243, Percent_Identity=33.3333333333333, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI23397609, Length=244, Percent_Identity=33.1967213114754, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24639444, Length=244, Percent_Identity=31.5573770491803, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21357041, Length=245, Percent_Identity=31.8367346938775, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644339, Length=248, Percent_Identity=29.8387096774194, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=31.0483870967742, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=27.0588235294118, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24948; Mature: 24816

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIQKVAIITAGGSGMGAASARRLAQDGFAVAILSSSGKGEALAKELGGIGVTGSNQSND
CCCEEEEEEEECCCCCCHHHHHHHHHCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCHH
DLQKLVDQTLEKWGRIDVLVNSAGHGPRAPILEITDEDWHKGMDTYFLNAVRPARLVVPA
HHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEECCCHHHCCHHHHHHHCCCCHHHHHHH
MQKQKSGVIINISTAWAFEPSAMFPTSAVFRAGLASFTKIFADTYAAENIRMNNVLPGWI
HHHCCCCEEEEEECEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHH
DSLPTTEERRESVPMQRYGKSEEIAATVSFLASDGAAYITGQNLRVDGGLTRSV
HCCCCCHHHHHCCCHHHCCCCHHHHHHHHHHHCCCEEEEECCCEEECCCCCCCC
>Mature Secondary Structure 
TIQKVAIITAGGSGMGAASARRLAQDGFAVAILSSSGKGEALAKELGGIGVTGSNQSND
CCEEEEEEEECCCCCCHHHHHHHHHCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCHH
DLQKLVDQTLEKWGRIDVLVNSAGHGPRAPILEITDEDWHKGMDTYFLNAVRPARLVVPA
HHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEECCCHHHCCHHHHHHHCCCCHHHHHHH
MQKQKSGVIINISTAWAFEPSAMFPTSAVFRAGLASFTKIFADTYAAENIRMNNVLPGWI
HHHCCCCEEEEEECEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHH
DSLPTTEERRESVPMQRYGKSEEIAATVSFLASDGAAYITGQNLRVDGGLTRSV
HCCCCCHHHHHCCCHHHCCCCHHHHHHHHHHHCCCEEEEECCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]