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The map label for this gene is slt [H]

Identifier: 225852166

GI number: 225852166

Start: 655626

End: 657683

Strand: Reverse

Name: slt [H]

Synonym: BMEA_A0681

Alternate gene names: 225852166

Gene position: 657683-655626 (Counterclockwise)

Preceding gene: 225852169

Following gene: 225852161

Centisome position: 30.94

GC content: 59.67

Gene sequence:

>2058_bases
ATGGTTTCACTTGCCCAATCGTCGCTACCGCCTGAAATCCCCACGCCGCTTGCGCGCCCCTTCGCGCCGACTGCCACCCA
TCAATCCCCAATCAGTCTGGTGACGCCGAGGCCCCGCCCCATCGCTCCTGATCCCATGGCCACGTCCGCCGTCAGCCGGA
CAGATAATCCGGCCGTGATCGGCGGAACATTGAAAAATGGCCTCGACGCGCTTAGCGCCAAGAATGTCGCAAGCGCCATC
GCTTCTCGCAACAACTTGCCGCGCGGCTCGCTCGACCGTCAGATTCTCACCTGGGCAATTGCAACCTCCGGCATGGATGG
TGTTCCCAGCACAGAGATTGCGGCCGCAGCATCCGAACTTTCAGGATGGCCCGGCATGGCCACCTTGCGCCGGAATTCAG
AACGGGCGCTTTTCAAGGAAAATCCTTCTTCTGCAACCATCATCGCCACTTTCGGCAGCACACGTCCACAGACCACGGAA
GGCATGATCGCTTTGGCACGCGCCTATGTGGCGACAGGCAATTCCACCAAGGCGCACCAGCTTCTCTCACCTTGGTGGAC
CAGGAAGCGTCTTTCATCCGACGATGAGCAGAAGATCCTGAAAGAATTTTCGGCGATTCTCACCCGCGAGGATCACCAAC
GCAGGCTGCTGCACTCTCTCTATAATGGCCACCTGCAATCGGCCCGGCTTCTTGCCGGGCCTGCGCAGGCGCAATCTCTT
TATAATGCCTATGCCGCAGTGGCGCAGAAATCACCCAACGCCGCCAGTGCAATCGCCGCCGTGGACCGCTCCTGGCAGGC
CAATCCGGTCTATCAGTTTTTAAAAATTCGCTATCTGCGCCGCGCCGAGCGTTACAACGAGGCTGCCGAGCTTCTGTTGA
AAGCGCCACGGAAGGCTTCCGTTCTTGTCGATCCCGATGCCTGGTGGGTGGAACGGCGCATCCTGTCACGCGAACTTCTC
GATCTCGGAAAGCCGCAACTTGCCTATCGGCTTGCCGCGGCCCATGCCGCCGAAACGCCCACCATGGCGGCGGAAGCCGA
ATTCCACGCGGGCTGGTATGCGCTTCGCGCCCTGAACCAACCGAAGCTGGCAGCGCCCCATTTTGCAAAAATCACGCAAA
TTTCGGCGCGCCCCATCTCCGCTTCCCGTGCCTATTACTGGCTTGGGCGGGCAGCGGAAGCTGGTTCTGGCGGCGATGCA
CGCGCCTATTACCGGCGGTCGGCGCATTTCGGCACCACTTTTTATGGCCAGCTTGCGGCCGCCAAGCTGAATGAGAAGGC
TCCTGAACTCGCCTATCCCAAGCCCACGGAAGCAGAGCGTGTGCGCTTTGCAAGCCGCCCCGCCGTGCAGGCAATCAAAC
GGCTGGAGCAGGTCGGTTATGGAAACAAGGCTGCGGCTCTTTACACACAGCTTTCGCAAGAACTCGACAGTGTGGGAGAA
CTCGCCCTGCTCGCCGTGATGGCTGAGCGGAACGACAATCATTATATGGCGCTGCGCGTCGGCAAAACGGCGGCAATGCG
CGGGCTCGATGTCGGCGCACTTTCCCATCCGCTCGGCGCAATCCCTGCAAGCGCGAATATCAAGGGTTCCGGCAAGGCGC
TTGCCTATGCCATCGCGCGGCAGGAAAGCGAATTCAATGTCAGCGCAGTTTCAAAAGCAGGCGCGCGCGGCCTGCTGCAA
CTTATGCCCGCCACAGCAAAAACGGTCGCCACACGCAACGGAATGAGCTTTTCCGCGCAGAAGCTTACGGCAGATGCGGC
CTATAATGCCACGCTCGGCGCACATTTTCTCGGTGAGCAGCTGGATCGTTTCAACGGTTCCTATGTACTCACCTTCGCCG
GGTATAATGCCGGGCCGCGCCGCGCCTCCGAATGGGTGGAGAAATATGGCGACCCGCGCGGCAAATCTGTCGAACAGGTC
GTGGATTGGATTGAGCGCATCCCCTATTCCGAAACGCGCAATTATGTGCAGCGCGTGATGGAAAATTACGAAGTCTATAA
GACCCGGCTGACTGGCCGTGCCGATATCAAGACCGATCTGGTTTATGGGCGACGCTGA

Upstream 100 bases:

>100_bases
TCCTTATTCCAGTCAGGCCATGTTTAAAAAAGTCGCAGCGATCTCTTCCAGGCGAACAGTGCTCCTAGCAGGTTGCTTCA
TCGCGGCTGCCGTCCAGCCG

Downstream 100 bases:

>100_bases
TAAGTAGCTTCTCCAAAGAAACCGGGGCGGTTCCAGCATAAACCGGAGCCGCCCCCACTGGTTCAGCCAGCCTGTTTTTT
TGCGCGCCGCGTTCCTGATC

Product: lytic transglycosylase catalytic

Products: 1,6-Anhydrobond [C]

Alternate protein names: Peptidoglycan lytic exotransglycosylase [H]

Number of amino acids: Translated: 685; Mature: 685

Protein sequence:

>685_residues
MVSLAQSSLPPEIPTPLARPFAPTATHQSPISLVTPRPRPIAPDPMATSAVSRTDNPAVIGGTLKNGLDALSAKNVASAI
ASRNNLPRGSLDRQILTWAIATSGMDGVPSTEIAAAASELSGWPGMATLRRNSERALFKENPSSATIIATFGSTRPQTTE
GMIALARAYVATGNSTKAHQLLSPWWTRKRLSSDDEQKILKEFSAILTREDHQRRLLHSLYNGHLQSARLLAGPAQAQSL
YNAYAAVAQKSPNAASAIAAVDRSWQANPVYQFLKIRYLRRAERYNEAAELLLKAPRKASVLVDPDAWWVERRILSRELL
DLGKPQLAYRLAAAHAAETPTMAAEAEFHAGWYALRALNQPKLAAPHFAKITQISARPISASRAYYWLGRAAEAGSGGDA
RAYYRRSAHFGTTFYGQLAAAKLNEKAPELAYPKPTEAERVRFASRPAVQAIKRLEQVGYGNKAAALYTQLSQELDSVGE
LALLAVMAERNDNHYMALRVGKTAAMRGLDVGALSHPLGAIPASANIKGSGKALAYAIARQESEFNVSAVSKAGARGLLQ
LMPATAKTVATRNGMSFSAQKLTADAAYNATLGAHFLGEQLDRFNGSYVLTFAGYNAGPRRASEWVEKYGDPRGKSVEQV
VDWIERIPYSETRNYVQRVMENYEVYKTRLTGRADIKTDLVYGRR

Sequences:

>Translated_685_residues
MVSLAQSSLPPEIPTPLARPFAPTATHQSPISLVTPRPRPIAPDPMATSAVSRTDNPAVIGGTLKNGLDALSAKNVASAI
ASRNNLPRGSLDRQILTWAIATSGMDGVPSTEIAAAASELSGWPGMATLRRNSERALFKENPSSATIIATFGSTRPQTTE
GMIALARAYVATGNSTKAHQLLSPWWTRKRLSSDDEQKILKEFSAILTREDHQRRLLHSLYNGHLQSARLLAGPAQAQSL
YNAYAAVAQKSPNAASAIAAVDRSWQANPVYQFLKIRYLRRAERYNEAAELLLKAPRKASVLVDPDAWWVERRILSRELL
DLGKPQLAYRLAAAHAAETPTMAAEAEFHAGWYALRALNQPKLAAPHFAKITQISARPISASRAYYWLGRAAEAGSGGDA
RAYYRRSAHFGTTFYGQLAAAKLNEKAPELAYPKPTEAERVRFASRPAVQAIKRLEQVGYGNKAAALYTQLSQELDSVGE
LALLAVMAERNDNHYMALRVGKTAAMRGLDVGALSHPLGAIPASANIKGSGKALAYAIARQESEFNVSAVSKAGARGLLQ
LMPATAKTVATRNGMSFSAQKLTADAAYNATLGAHFLGEQLDRFNGSYVLTFAGYNAGPRRASEWVEKYGDPRGKSVEQV
VDWIERIPYSETRNYVQRVMENYEVYKTRLTGRADIKTDLVYGRR
>Mature_685_residues
MVSLAQSSLPPEIPTPLARPFAPTATHQSPISLVTPRPRPIAPDPMATSAVSRTDNPAVIGGTLKNGLDALSAKNVASAI
ASRNNLPRGSLDRQILTWAIATSGMDGVPSTEIAAAASELSGWPGMATLRRNSERALFKENPSSATIIATFGSTRPQTTE
GMIALARAYVATGNSTKAHQLLSPWWTRKRLSSDDEQKILKEFSAILTREDHQRRLLHSLYNGHLQSARLLAGPAQAQSL
YNAYAAVAQKSPNAASAIAAVDRSWQANPVYQFLKIRYLRRAERYNEAAELLLKAPRKASVLVDPDAWWVERRILSRELL
DLGKPQLAYRLAAAHAAETPTMAAEAEFHAGWYALRALNQPKLAAPHFAKITQISARPISASRAYYWLGRAAEAGSGGDA
RAYYRRSAHFGTTFYGQLAAAKLNEKAPELAYPKPTEAERVRFASRPAVQAIKRLEQVGYGNKAAALYTQLSQELDSVGE
LALLAVMAERNDNHYMALRVGKTAAMRGLDVGALSHPLGAIPASANIKGSGKALAYAIARQESEFNVSAVSKAGARGLLQ
LMPATAKTVATRNGMSFSAQKLTADAAYNATLGAHFLGEQLDRFNGSYVLTFAGYNAGPRRASEWVEKYGDPRGKSVEQV
VDWIERIPYSETRNYVQRVMENYEVYKTRLTGRADIKTDLVYGRR

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI87082441, Length=277, Percent_Identity=29.9638989169675, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011989
- InterPro:   IPR016026
- InterPro:   IPR008258
- InterPro:   IPR012289
- InterPro:   IPR008939
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 74557; Mature: 74557

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSLAQSSLPPEIPTPLARPFAPTATHQSPISLVTPRPRPIAPDPMATSAVSRTDNPAVI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHCCCCCEEE
GGTLKNGLDALSAKNVASAIASRNNLPRGSLDRQILTWAIATSGMDGVPSTEIAAAASEL
ECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
SGWPGMATLRRNSERALFKENPSSATIIATFGSTRPQTTEGMIALARAYVATGNSTKAHQ
CCCCCHHHHHCCCCCCCEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHH
LLSPWWTRKRLSSDDEQKILKEFSAILTREDHQRRLLHSLYNGHLQSARLLAGPAQAQSL
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHCHHHHCCHHHHHHH
YNAYAAVAQKSPNAASAIAAVDRSWQANPVYQFLKIRYLRRAERYNEAAELLLKAPRKAS
HHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VLVDPDAWWVERRILSRELLDLGKPQLAYRLAAAHAAETPTMAAEAEFHAGWYALRALNQ
EEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHCCC
PKLAAPHFAKITQISARPISASRAYYWLGRAAEAGSGGDARAYYRRSAHFGTTFYGQLAA
CCCCCCCHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHH
AKLNEKAPELAYPKPTEAERVRFASRPAVQAIKRLEQVGYGNKAAALYTQLSQELDSVGE
HHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LALLAVMAERNDNHYMALRVGKTAAMRGLDVGALSHPLGAIPASANIKGSGKALAYAIAR
HHHHHHHHHCCCCEEEEEEECCHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHH
QESEFNVSAVSKAGARGLLQLMPATAKTVATRNGMSFSAQKLTADAAYNATLGAHFLGEQ
CCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHHHH
LDRFNGSYVLTFAGYNAGPRRASEWVEKYGDPRGKSVEQVVDWIERIPYSETRNYVQRVM
HHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
ENYEVYKTRLTGRADIKTDLVYGRR
HHHHHHHHHCCCCCCCHHCCCCCCC
>Mature Secondary Structure
MVSLAQSSLPPEIPTPLARPFAPTATHQSPISLVTPRPRPIAPDPMATSAVSRTDNPAVI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHCCCCCEEE
GGTLKNGLDALSAKNVASAIASRNNLPRGSLDRQILTWAIATSGMDGVPSTEIAAAASEL
ECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
SGWPGMATLRRNSERALFKENPSSATIIATFGSTRPQTTEGMIALARAYVATGNSTKAHQ
CCCCCHHHHHCCCCCCCEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHH
LLSPWWTRKRLSSDDEQKILKEFSAILTREDHQRRLLHSLYNGHLQSARLLAGPAQAQSL
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHCHHHHCCHHHHHHH
YNAYAAVAQKSPNAASAIAAVDRSWQANPVYQFLKIRYLRRAERYNEAAELLLKAPRKAS
HHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VLVDPDAWWVERRILSRELLDLGKPQLAYRLAAAHAAETPTMAAEAEFHAGWYALRALNQ
EEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHCCC
PKLAAPHFAKITQISARPISASRAYYWLGRAAEAGSGGDARAYYRRSAHFGTTFYGQLAA
CCCCCCCHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHH
AKLNEKAPELAYPKPTEAERVRFASRPAVQAIKRLEQVGYGNKAAALYTQLSQELDSVGE
HHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LALLAVMAERNDNHYMALRVGKTAAMRGLDVGALSHPLGAIPASANIKGSGKALAYAIAR
HHHHHHHHHCCCCEEEEEEECCHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHH
QESEFNVSAVSKAGARGLLQLMPATAKTVATRNGMSFSAQKLTADAAYNATLGAHFLGEQ
CCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHHHH
LDRFNGSYVLTFAGYNAGPRRASEWVEKYGDPRGKSVEQVVDWIERIPYSETRNYVQRVM
HHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
ENYEVYKTRLTGRADIKTDLVYGRR
HHHHHHHHHCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]