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The map label for this gene is ptrB [H]

Identifier: 225852097

GI number: 225852097

Start: 582272

End: 584380

Strand: Reverse

Name: ptrB [H]

Synonym: BMEA_A0607

Alternate gene names: 225852097

Gene position: 584380-582272 (Counterclockwise)

Preceding gene: 225852100

Following gene: 225852096

Centisome position: 27.49

GC content: 57.89

Gene sequence:

>2109_bases
ATGCCCCAGGATTTCCTACGCCCTCTTCCTCCGCACGCTCCCAAGCACCCCGCAAGCGACACACGGCACGGCATCACCCG
CACGGATGACTATGCGTGGCTGCGCGCTGAAAACTGGCAGGAAGTGTTCCGCGATCCTTCTGTTCTGGCGCCGGAAATCC
GCGCGCACCTGGACGCGGAAAACGCCTATCAAGCCGCCTTGATGAAAGATACGGAAAACCTGCAAAAGGTGCTTTTTGCC
GAGATGCGCGGGCGCATCAAGGAAGACGATTCTTCCGTTCCGGCCAAGGACGGCCCCTATGCCTATGGCGTCTCCTATCG
CACTGGCGGCGAACAGCCCTATTTCATCCGCACGCCGCGCGATGGCGGGCCGGAAACCATCCTGCTCGACGGCGACAGGG
AAGGCGAAGGCAAGGCCTATTTCCGCCTCGCCTCCGCCGATCATGCCCCAAACCACAATCTCCTCATCTGGGGGTATGAC
GACAAGGGATCGGAATTTTACAAGCTGAAGGTGCGCGATCTCACCACCATGGCCGACCTTGAAGATATCGTTACCGATAC
CAATGGCGGCGGCGCGTGGGATGCGAAAAGCGAAGGCTTCTTCTACACACGGCTTGATGAAAACCACCGCCCGTCAAAGG
TTTTCTACCACAAGATCGGCACACAGCAGGCAGACGACAAGCTGATTTATGAGGAAACCGATCCGGGCTTTTTCCTCGGT
GTGGGCGGCTCCGCGCTCGACGATTATATCTTCATCGACATTCACGACCACGAAACATCCGAATGCTGGCTTTTGCCCGC
AGACGATCCGTCAGCCGAACCGAAGCTCGTCATGGCGCGCAAGGCCGGCACTGAATATGATATCGCGCCGGGCGGCGATG
TTTTCTATATTCTCACTAATGCGGACGGAGCCAAGGACTTCAAGATCTGCCAGGCGCCAGCTTCCGCGCCACAGCCTGAA
AACTGGCAGGAAATCGTCGCCGAAAAGCCGGGCCGACTGATTCTCTCCCATTCAGCCTATAAGCACCATCTTGTCTGGAT
CGAACGCGACAACGGTCTGCCGCGCATCGTCATCCATGATCGCAAGACCGGCGAGGAGCACGCCATCGCTTTCGATGAGG
AGGCCTATTCGCTGGGACTGCATGGCAGCGCCGAATATGATACGGATGTCATCCGTTTTTCCTATTCGTCGATGACGACG
CCGGAACAGCTCTTCGATTATAATATGCGCACGCGCGAACGCACGCTCCTGAAGACGCAGGAAGTGCCCTCGGGCCACAA
TCCGCAGGACTATGTGACGCGCCGCATTCTGGCCCCCGCCTTCGATGGTGAACTCGTGCCGGTTTCGCTGCTCTATCACA
AGGACACGAAGCTGGACGGCTCCGCGCCTTGCCTTCTCTACGGCTATGGCTCCTATGGCATCACCATTCCGGCAAGCTTC
AGCACATCGCGCCTTTCGCTTGTCGATCGTGGCTTCGTTTATGCAATCGCGCATATTCGCGGCGGCAAGGACAAGGGGTT
CGCCTGGTACGAAAACGGAAAGCGCGACAAGAAGACCAATACGTTCAAGGACTTCATTGCCGCAGCGCAGCATCTCGTCA
AGGAAGGCTTCACCAGCCATGACCGCATCGTCGCCCATGGCGGCTCGGCGGGCGGGATGCTGATGGGCGCCATCGCCAAT
ATGGCGCCGCAAGCCTTTGGCGGCATCATTGCCGAAGTACCCTTCGTCGATGTGCTGAATACAATGCTGGACGACACCCT
GCCGCTCACCCCACCGGAATGGCCCGAATGGGGTAATCCGATTGCTTCCGAAGCAGATTATCGCACCATTGCCAGCTATT
CACCCTATGACAATGTAACGGCGCAGGCCTATCCGGCCATTCTGGCGGTTGCGGGGCTCACCGATCCACGCGTTACCTAT
TGGGAACCCGCCAAGTGGGTGGCGAAACTGCGTGAATTGAAGACCGACAGCCATCCGGTCCTGTTCCGCATCAATATGGA
TGCTGGACATGCAGGCGCTTCCGGCCGCTTTTCGCGCCTTGAGGAAGTCGCCTATAGTTTCGCTTTCGCATTGAAGGTGG
TGGGTAAGGTTCCAAGCTTCAAAAACTGA

Upstream 100 bases:

>100_bases
CGGACATTTCCGGCAACTATATAGAGATGCATGTCACAGCTGAAAATGCGTCCCTTTGGCGCTTTTGAAGCAAATTGAAA
CCGGTTCACTGGAATTTTGA

Downstream 100 bases:

>100_bases
TTATCAAGCCTTTATCCTGCGAGGGCGGTTCCGTTTTAACGGAATCGCCGGAGCCACTCTAAGTATTTGTTTTGCCGCAT
TATCCTGAAAATACTCTACA

Product: protease 2

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 702; Mature: 701

Protein sequence:

>702_residues
MPQDFLRPLPPHAPKHPASDTRHGITRTDDYAWLRAENWQEVFRDPSVLAPEIRAHLDAENAYQAALMKDTENLQKVLFA
EMRGRIKEDDSSVPAKDGPYAYGVSYRTGGEQPYFIRTPRDGGPETILLDGDREGEGKAYFRLASADHAPNHNLLIWGYD
DKGSEFYKLKVRDLTTMADLEDIVTDTNGGGAWDAKSEGFFYTRLDENHRPSKVFYHKIGTQQADDKLIYEETDPGFFLG
VGGSALDDYIFIDIHDHETSECWLLPADDPSAEPKLVMARKAGTEYDIAPGGDVFYILTNADGAKDFKICQAPASAPQPE
NWQEIVAEKPGRLILSHSAYKHHLVWIERDNGLPRIVIHDRKTGEEHAIAFDEEAYSLGLHGSAEYDTDVIRFSYSSMTT
PEQLFDYNMRTRERTLLKTQEVPSGHNPQDYVTRRILAPAFDGELVPVSLLYHKDTKLDGSAPCLLYGYGSYGITIPASF
STSRLSLVDRGFVYAIAHIRGGKDKGFAWYENGKRDKKTNTFKDFIAAAQHLVKEGFTSHDRIVAHGGSAGGMLMGAIAN
MAPQAFGGIIAEVPFVDVLNTMLDDTLPLTPPEWPEWGNPIASEADYRTIASYSPYDNVTAQAYPAILAVAGLTDPRVTY
WEPAKWVAKLRELKTDSHPVLFRINMDAGHAGASGRFSRLEEVAYSFAFALKVVGKVPSFKN

Sequences:

>Translated_702_residues
MPQDFLRPLPPHAPKHPASDTRHGITRTDDYAWLRAENWQEVFRDPSVLAPEIRAHLDAENAYQAALMKDTENLQKVLFA
EMRGRIKEDDSSVPAKDGPYAYGVSYRTGGEQPYFIRTPRDGGPETILLDGDREGEGKAYFRLASADHAPNHNLLIWGYD
DKGSEFYKLKVRDLTTMADLEDIVTDTNGGGAWDAKSEGFFYTRLDENHRPSKVFYHKIGTQQADDKLIYEETDPGFFLG
VGGSALDDYIFIDIHDHETSECWLLPADDPSAEPKLVMARKAGTEYDIAPGGDVFYILTNADGAKDFKICQAPASAPQPE
NWQEIVAEKPGRLILSHSAYKHHLVWIERDNGLPRIVIHDRKTGEEHAIAFDEEAYSLGLHGSAEYDTDVIRFSYSSMTT
PEQLFDYNMRTRERTLLKTQEVPSGHNPQDYVTRRILAPAFDGELVPVSLLYHKDTKLDGSAPCLLYGYGSYGITIPASF
STSRLSLVDRGFVYAIAHIRGGKDKGFAWYENGKRDKKTNTFKDFIAAAQHLVKEGFTSHDRIVAHGGSAGGMLMGAIAN
MAPQAFGGIIAEVPFVDVLNTMLDDTLPLTPPEWPEWGNPIASEADYRTIASYSPYDNVTAQAYPAILAVAGLTDPRVTY
WEPAKWVAKLRELKTDSHPVLFRINMDAGHAGASGRFSRLEEVAYSFAFALKVVGKVPSFKN
>Mature_701_residues
PQDFLRPLPPHAPKHPASDTRHGITRTDDYAWLRAENWQEVFRDPSVLAPEIRAHLDAENAYQAALMKDTENLQKVLFAE
MRGRIKEDDSSVPAKDGPYAYGVSYRTGGEQPYFIRTPRDGGPETILLDGDREGEGKAYFRLASADHAPNHNLLIWGYDD
KGSEFYKLKVRDLTTMADLEDIVTDTNGGGAWDAKSEGFFYTRLDENHRPSKVFYHKIGTQQADDKLIYEETDPGFFLGV
GGSALDDYIFIDIHDHETSECWLLPADDPSAEPKLVMARKAGTEYDIAPGGDVFYILTNADGAKDFKICQAPASAPQPEN
WQEIVAEKPGRLILSHSAYKHHLVWIERDNGLPRIVIHDRKTGEEHAIAFDEEAYSLGLHGSAEYDTDVIRFSYSSMTTP
EQLFDYNMRTRERTLLKTQEVPSGHNPQDYVTRRILAPAFDGELVPVSLLYHKDTKLDGSAPCLLYGYGSYGITIPASFS
TSRLSLVDRGFVYAIAHIRGGKDKGFAWYENGKRDKKTNTFKDFIAAAQHLVKEGFTSHDRIVAHGGSAGGMLMGAIANM
APQAFGGIIAEVPFVDVLNTMLDDTLPLTPPEWPEWGNPIASEADYRTIASYSPYDNVTAQAYPAILAVAGLTDPRVTYW
EPAKWVAKLRELKTDSHPVLFRINMDAGHAGASGRFSRLEEVAYSFAFALKVVGKVPSFKN

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI284172438, Length=462, Percent_Identity=29.4372294372294, Blast_Score=197, Evalue=4e-50,
Organism=Homo sapiens, GI284172431, Length=462, Percent_Identity=29.4372294372294, Blast_Score=197, Evalue=4e-50,
Organism=Homo sapiens, GI284172420, Length=462, Percent_Identity=29.4372294372294, Blast_Score=197, Evalue=4e-50,
Organism=Homo sapiens, GI284172413, Length=462, Percent_Identity=29.4372294372294, Blast_Score=197, Evalue=4e-50,
Organism=Homo sapiens, GI70778815, Length=462, Percent_Identity=29.4372294372294, Blast_Score=197, Evalue=4e-50,
Organism=Homo sapiens, GI41349456, Length=718, Percent_Identity=25.3481894150418, Blast_Score=194, Evalue=4e-49,
Organism=Homo sapiens, GI108860686, Length=232, Percent_Identity=37.5, Blast_Score=147, Evalue=4e-35,
Organism=Homo sapiens, GI108860692, Length=211, Percent_Identity=38.3886255924171, Blast_Score=144, Evalue=4e-34,
Organism=Escherichia coli, GI1788150, Length=696, Percent_Identity=39.2241379310345, Blast_Score=456, Evalue=1e-129,
Organism=Drosophila melanogaster, GI24583414, Length=749, Percent_Identity=24.0320427236315, Blast_Score=186, Evalue=5e-47,
Organism=Drosophila melanogaster, GI221510989, Length=739, Percent_Identity=23.4100135317997, Blast_Score=158, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 78244; Mature: 78113

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00708 PRO_ENDOPEP_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQDFLRPLPPHAPKHPASDTRHGITRTDDYAWLRAENWQEVFRDPSVLAPEIRAHLDAE
CCHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHCCCCCCCCHHHHHCCCC
NAYQAALMKDTENLQKVLFAEMRGRIKEDDSSVPAKDGPYAYGVSYRTGGEQPYFIRTPR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEECCC
DGGPETILLDGDREGEGKAYFRLASADHAPNHNLLIWGYDDKGSEFYKLKVRDLTTMADL
CCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEEEEEHHHHHHHH
EDIVTDTNGGGAWDAKSEGFFYTRLDENHRPSKVFYHKIGTQQADDKLIYEETDPGFFLG
HHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCEEEEECCCCEEEE
VGGSALDDYIFIDIHDHETSECWLLPADDPSAEPKLVMARKAGTEYDIAPGGDVFYILTN
CCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCCEEEEECCCCCEECCCCCCEEEEEEC
ADGAKDFKICQAPASAPQPENWQEIVAEKPGRLILSHSAYKHHLVWIERDNGLPRIVIHD
CCCCCCCEEEECCCCCCCCCCHHHHHHCCCCCEEEECCCCEEEEEEEECCCCCCEEEEEC
RKTGEEHAIAFDEEAYSLGLHGSAEYDTDVIRFSYSSMTTPEQLFDYNMRTRERTLLKTQ
CCCCCCCEEEECCCCEEECCCCCCCCCCEEEEEECCCCCCHHHHHCCCCCHHHHHHHHHH
EVPSGHNPQDYVTRRILAPAFDGELVPVSLLYHKDTKLDGSAPCLLYGYGSYGITIPASF
CCCCCCCCHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCEEEEEECCCCEEEECCC
STSRLSLVDRGFVYAIAHIRGGKDKGFAWYENGKRDKKTNTFKDFIAAAQHLVKEGFTSH
CCCHHHHHHCCEEEEEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
DRIVAHGGSAGGMLMGAIANMAPQAFGGIIAEVPFVDVLNTMLDDTLPLTPPEWPEWGNP
CEEEEECCCCCCHHHHHHHHHCHHHHCCHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCC
IASEADYRTIASYSPYDNVTAQAYPAILAVAGLTDPRVTYWEPAKWVAKLRELKTDSHPV
CCCCCCCCEEECCCCCCCCCHHHHCEEEEEECCCCCCCEEECHHHHHHHHHHHCCCCCCE
LFRINMDAGHAGASGRFSRLEEVAYSFAFALKVVGKVPSFKN
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PQDFLRPLPPHAPKHPASDTRHGITRTDDYAWLRAENWQEVFRDPSVLAPEIRAHLDAE
CHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHCCCCCCCCHHHHHCCCC
NAYQAALMKDTENLQKVLFAEMRGRIKEDDSSVPAKDGPYAYGVSYRTGGEQPYFIRTPR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEECCC
DGGPETILLDGDREGEGKAYFRLASADHAPNHNLLIWGYDDKGSEFYKLKVRDLTTMADL
CCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEEEEEHHHHHHHH
EDIVTDTNGGGAWDAKSEGFFYTRLDENHRPSKVFYHKIGTQQADDKLIYEETDPGFFLG
HHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCEEEEECCCCEEEE
VGGSALDDYIFIDIHDHETSECWLLPADDPSAEPKLVMARKAGTEYDIAPGGDVFYILTN
CCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCCEEEEECCCCCEECCCCCCEEEEEEC
ADGAKDFKICQAPASAPQPENWQEIVAEKPGRLILSHSAYKHHLVWIERDNGLPRIVIHD
CCCCCCCEEEECCCCCCCCCCHHHHHHCCCCCEEEECCCCEEEEEEEECCCCCCEEEEEC
RKTGEEHAIAFDEEAYSLGLHGSAEYDTDVIRFSYSSMTTPEQLFDYNMRTRERTLLKTQ
CCCCCCCEEEECCCCEEECCCCCCCCCCEEEEEECCCCCCHHHHHCCCCCHHHHHHHHHH
EVPSGHNPQDYVTRRILAPAFDGELVPVSLLYHKDTKLDGSAPCLLYGYGSYGITIPASF
CCCCCCCCHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCEEEEEECCCCEEEECCC
STSRLSLVDRGFVYAIAHIRGGKDKGFAWYENGKRDKKTNTFKDFIAAAQHLVKEGFTSH
CCCHHHHHHCCEEEEEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
DRIVAHGGSAGGMLMGAIANMAPQAFGGIIAEVPFVDVLNTMLDDTLPLTPPEWPEWGNP
CEEEEECCCCCCHHHHHHHHHCHHHHCCHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCC
IASEADYRTIASYSPYDNVTAQAYPAILAVAGLTDPRVTYWEPAKWVAKLRELKTDSHPV
CCCCCCCCEEECCCCCCCCCHHHHCEEEEEECCCCCCCEEECHHHHHHHHHHHCCCCCCE
LFRINMDAGHAGASGRFSRLEEVAYSFAFALKVVGKVPSFKN
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]