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The map label for this gene is ycbL [C]

Identifier: 225852040

GI number: 225852040

Start: 525804

End: 526709

Strand: Reverse

Name: ycbL [C]

Synonym: BMEA_A0541

Alternate gene names: 225852040

Gene position: 526709-525804 (Counterclockwise)

Preceding gene: 225852046

Following gene: 225852038

Centisome position: 24.78

GC content: 61.15

Gene sequence:

>906_bases
ATGGCGCTTGTTTTCGACAATAATTTCACGCCCGAATATGGCAAGCCTGTCACGCTTGGCAAAGGCATTGTGCGCCTGAC
GGCCAACAACCCCAGTGCCTTCACCTTTCATGGCACCAACAGCTATATCGTGGGAACCGATACGCTTGCGATCATCGATC
CCGGCCCGGAAAACGAGGCGCATTACCGCGCCCTGCTCGAAACAGTGGCGGGGCGTCCGGTAAGCCATATTTTCGTGAGC
CACACCCATCGCGATCACTCGCCGCTTGCGCAACGGCTCAAGGAAGAACTTGGCGCACTGACAGTCGCCGAAGGCCCGCA
CCGGCCTGCCCGGCCCTATCATGCAGGTGAAGTCAACCTGCTCGAAGCAAGCGCAGATATGGATTTCAGGCCCGATATCC
TGCTTGCCGACGGGGCAACCGTCGATGGCGACGGCTGGGCGCTTGAAGGCATTCACACACCGGGCCACACCGCCAACCAT
ATGGCTTTTGCGCTGAAAGGCACCGATATTCTCTTTTCGGCGGATCATGTGATGGCATGGGCCACGCCCGTCGTCGCGCC
GCCTGACGGATCGATGAGCGACTATATGGCATCGCTCGAAAAGCTTCTGGCACGGGACGATGCGGCCTATCTGCCCGGCC
ATGGCGGCGCGGTGACGAAGCCGGCCGCCTTTGTGCGGGGCCTGCGTGCCCACCGCAAAATGCGTGAGCGCGCGATCCTC
GAGCGCATTGTGCAGGGCGACCGCACCATTCGCGACATGGTGAAGGTGATCTATCGCGACACCGACCCGCGCCTGCATGG
TGCAGCGGCACTTTCGGTGCTGGCGCATCTGGAAGATCTGGTCGGGCGCGGCGAAATCATAACCGAAGGCGACCCGTCGC
TGAACGGTATCTATCAGCCAGCCTGA

Upstream 100 bases:

>100_bases
CGATTGTTACCGGGCTTTGGCGAATAACGTTTGAAACCCGATTATATAAGGCCTATGCCGTTTCAGGAATCGAACCAAAG
AACAATTGGATGCCGTTTCC

Downstream 100 bases:

>100_bases
TTATTCGACATCGGCCGGAGCCTTATTGACCTCCCCCTCCAGCGCGCCCAGAAAATCAGTGATGAAACCGGCATTCAGCC
CCCTATCGCGCTTTCCATAA

Product: beta-lactamase domain-containing protein

Products: glutathione; 2-hydroxy carboxylate

Alternate protein names: Beta-Lactamase Domain Protein; Metallo-Beta-Lactamase Family Protein; Hydrolase; Metallo-Beta-Lactamase Superfamily Protein; Beta-Lactamase-Like; Zn-Dependent Hydrolase Glyoxylase; Beta-Lactamase Family Protein; Beta-Lactamase-Like Protein; Beta-Lactamase; Hydroxyacylglutathione Hydrolase; Metallo-Beta-Lactamase Family Hydrolase; Metallo-Beta-Lactamase Domain Protein; Beta-Lactamase Class B; Hydrolase Protein; Zinc-Dependent Hydrolase; Hydrolase/Glyoxylase; Zn-Dependent Hydrolase; Nudix Hydrolase; NUDIX HydrolaseBeta-Lactamase-Like; Beta-Lactamase-Like Hydrolase

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MALVFDNNFTPEYGKPVTLGKGIVRLTANNPSAFTFHGTNSYIVGTDTLAIIDPGPENEAHYRALLETVAGRPVSHIFVS
HTHRDHSPLAQRLKEELGALTVAEGPHRPARPYHAGEVNLLEASADMDFRPDILLADGATVDGDGWALEGIHTPGHTANH
MAFALKGTDILFSADHVMAWATPVVAPPDGSMSDYMASLEKLLARDDAAYLPGHGGAVTKPAAFVRGLRAHRKMRERAIL
ERIVQGDRTIRDMVKVIYRDTDPRLHGAAALSVLAHLEDLVGRGEIITEGDPSLNGIYQPA

Sequences:

>Translated_301_residues
MALVFDNNFTPEYGKPVTLGKGIVRLTANNPSAFTFHGTNSYIVGTDTLAIIDPGPENEAHYRALLETVAGRPVSHIFVS
HTHRDHSPLAQRLKEELGALTVAEGPHRPARPYHAGEVNLLEASADMDFRPDILLADGATVDGDGWALEGIHTPGHTANH
MAFALKGTDILFSADHVMAWATPVVAPPDGSMSDYMASLEKLLARDDAAYLPGHGGAVTKPAAFVRGLRAHRKMRERAIL
ERIVQGDRTIRDMVKVIYRDTDPRLHGAAALSVLAHLEDLVGRGEIITEGDPSLNGIYQPA
>Mature_300_residues
ALVFDNNFTPEYGKPVTLGKGIVRLTANNPSAFTFHGTNSYIVGTDTLAIIDPGPENEAHYRALLETVAGRPVSHIFVSH
THRDHSPLAQRLKEELGALTVAEGPHRPARPYHAGEVNLLEASADMDFRPDILLADGATVDGDGWALEGIHTPGHTANHM
AFALKGTDILFSADHVMAWATPVVAPPDGSMSDYMASLEKLLARDDAAYLPGHGGAVTKPAAFVRGLRAHRKMRERAILE
RIVQGDRTIRDMVKVIYRDTDPRLHGAAALSVLAHLEDLVGRGEIITEGDPSLNGIYQPA

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7705793, Length=285, Percent_Identity=30.1754385964912, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17537503, Length=271, Percent_Identity=28.7822878228782, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI193205216, Length=271, Percent_Identity=28.7822878228782, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI20129357, Length=301, Percent_Identity=30.2325581395349, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.2.6

Molecular weight: Translated: 32534; Mature: 32403

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVFDNNFTPEYGKPVTLGKGIVRLTANNPSAFTFHGTNSYIVGTDTLAIIDPGPENEA
CEEEECCCCCCCCCCCEEECCCEEEEECCCCCEEEEECCCCEEEECCEEEEECCCCCCHH
HYRALLETVAGRPVSHIFVSHTHRDHSPLAQRLKEELGALTVAEGPHRPARPYHAGEVNL
HHHHHHHHHHCCCHHEEEEECCCCCCHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCEEE
LEASADMDFRPDILLADGATVDGDGWALEGIHTPGHTANHMAFALKGTDILFSADHVMAW
EEECCCCCCCCCEEEECCCEECCCCEEEECCCCCCCCCCCEEEEEECCEEEEECCCEEEE
ATPVVAPPDGSMSDYMASLEKLLARDDAAYLPGHGGAVTKPAAFVRGLRAHRKMRERAIL
CCCEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ERIVQGDRTIRDMVKVIYRDTDPRLHGAAALSVLAHLEDLVGRGEIITEGDPSLNGIYQP
HHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCC
A
C
>Mature Secondary Structure 
ALVFDNNFTPEYGKPVTLGKGIVRLTANNPSAFTFHGTNSYIVGTDTLAIIDPGPENEA
EEEECCCCCCCCCCCEEECCCEEEEECCCCCEEEEECCCCEEEECCEEEEECCCCCCHH
HYRALLETVAGRPVSHIFVSHTHRDHSPLAQRLKEELGALTVAEGPHRPARPYHAGEVNL
HHHHHHHHHHCCCHHEEEEECCCCCCHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCEEE
LEASADMDFRPDILLADGATVDGDGWALEGIHTPGHTANHMAFALKGTDILFSADHVMAW
EEECCCCCCCCCEEEECCCEECCCCEEEECCCCCCCCCCCEEEEEECCEEEEECCCEEEE
ATPVVAPPDGSMSDYMASLEKLLARDDAAYLPGHGGAVTKPAAFVRGLRAHRKMRERAIL
CCCEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ERIVQGDRTIRDMVKVIYRDTDPRLHGAAALSVLAHLEDLVGRGEIITEGDPSLNGIYQP
HHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-(2-hydroxyacyl)glutathione; H2O

Specific reaction: S-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA