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The map label for this gene is 225852014

Identifier: 225852014

GI number: 225852014

Start: 495938

End: 496423

Strand: Reverse

Name: 225852014

Synonym: BMEA_A0514

Alternate gene names: NA

Gene position: 496423-495938 (Counterclockwise)

Preceding gene: 225852015

Following gene: 225852002

Centisome position: 23.35

GC content: 58.85

Gene sequence:

>486_bases
ATGACGATCAAAGTTGGCGACAGGCTGCCCGCAGCGACTTTCAAGGTAAAGACCGCAGACGGCGTCACGGAAATGACGAC
CGACGATGTCTTCAAAGGCAGGAAGGTGGTTCTCTTTGCGGTGCCGGGTGCATTTACGCCGACCTGTAGCCTGAACCACC
TGCCGGGCTATCTTGAAAACCGCGATGCAATTCTCGCCAAGGGCGTGGACCAGATTGCAGTCGTTGCGGTGAACGACCCG
TTTGTCATGGGCGCCTGGGCGCAGAGCACCGGCGGCGAGGGCAAGATTCTCTTCCTCGCCGATGGAAGCGCAACCTTCAC
CAAAGCAGCCGGTCTCGATATCGATCTTTCCGGTGGCGGCCTCGGTGTACGTTCCAAGCGCTATTCCGCCATCGTCGAAG
ACGGCGTGGTGAAATCTCTCAATATCGAAGAACAGCCGGGCCAGGCGGTCACGTCTGCCGCCTCAGCCCTTCTCGCACAG
CTTTAA

Upstream 100 bases:

>100_bases
GTCGCCGTGCGTGCTTCGGCACGGCAAATCAAAAGTTTCGCACAAACAGCAGGCGGACCAGACGGCAATTTCCATCCGCC
CTGCCCTTAGGAGAAAATCG

Downstream 100 bases:

>100_bases
AAGTGAAAGGGCGGCGAAAGCCGCCCTTACTATTTCACCTTCAACGTGCGGTGCCCGGCATATTTGAACGGCTCCATGCC
AGCGCGGGCCAGTTCATCCG

Product: redoxin domain-containing protein

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MTIKVGDRLPAATFKVKTADGVTEMTTDDVFKGRKVVLFAVPGAFTPTCSLNHLPGYLENRDAILAKGVDQIAVVAVNDP
FVMGAWAQSTGGEGKILFLADGSATFTKAAGLDIDLSGGGLGVRSKRYSAIVEDGVVKSLNIEEQPGQAVTSAASALLAQ
L

Sequences:

>Translated_161_residues
MTIKVGDRLPAATFKVKTADGVTEMTTDDVFKGRKVVLFAVPGAFTPTCSLNHLPGYLENRDAILAKGVDQIAVVAVNDP
FVMGAWAQSTGGEGKILFLADGSATFTKAAGLDIDLSGGGLGVRSKRYSAIVEDGVVKSLNIEEQPGQAVTSAASALLAQ
L
>Mature_160_residues
TIKVGDRLPAATFKVKTADGVTEMTTDDVFKGRKVVLFAVPGAFTPTCSLNHLPGYLENRDAILAKGVDQIAVVAVNDPF
VMGAWAQSTGGEGKILFLADGSATFTKAAGLDIDLSGGGLGVRSKRYSAIVEDGVVKSLNIEEQPGQAVTSAASALLAQL

Specific function: Unknown

COG id: COG0678

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI6912238, Length=161, Percent_Identity=42.8571428571429, Blast_Score=123, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6323138, Length=134, Percent_Identity=37.3134328358209, Blast_Score=91, Evalue=1e-19,
Organism=Drosophila melanogaster, GI78706776, Length=143, Percent_Identity=51.0489510489511, Blast_Score=137, Evalue=4e-33,
Organism=Drosophila melanogaster, GI78709078, Length=143, Percent_Identity=51.0489510489511, Blast_Score=137, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR011906
- InterPro:   IPR014025
- InterPro:   IPR013740
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin; PF08534 Redoxin [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 16669; Mature: 16538

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKVGDRLPAATFKVKTADGVTEMTTDDVFKGRKVVLFAVPGAFTPTCSLNHLPGYLEN
CEEEECCCCCCEEEEEECCCCCCCCCCHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCC
RDAILAKGVDQIAVVAVNDPFVMGAWAQSTGGEGKILFLADGSATFTKAAGLDIDLSGGG
CCEEEECCCCEEEEEEECCCEEEEEECCCCCCCEEEEEEECCCCCEEEECCCEEEECCCC
LGVRSKRYSAIVEDGVVKSLNIEEQPGQAVTSAASALLAQL
CCCCCHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TIKVGDRLPAATFKVKTADGVTEMTTDDVFKGRKVVLFAVPGAFTPTCSLNHLPGYLEN
EEEECCCCCCEEEEEECCCCCCCCCCHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCC
RDAILAKGVDQIAVVAVNDPFVMGAWAQSTGGEGKILFLADGSATFTKAAGLDIDLSGGG
CCEEEECCCCEEEEEEECCCEEEEEECCCCCCCEEEEEEECCCCCEEEECCCEEEECCCC
LGVRSKRYSAIVEDGVVKSLNIEEQPGQAVTSAASALLAQL
CCCCCHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]