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The map label for this gene is murA

Identifier: 225851806

GI number: 225851806

Start: 284418

End: 285707

Strand: Reverse

Name: murA

Synonym: BMEA_A0289

Alternate gene names: 225851806

Gene position: 285707-284418 (Counterclockwise)

Preceding gene: 225851807

Following gene: 225851805

Centisome position: 13.44

GC content: 61.01

Gene sequence:

>1290_bases
ATGGATCGCATTAAAATCGTCGGCGGCAACAAGCTCAACGGCGTGATTCCCATTTCCGGCGCTAAAAACGCTGCCCTTCC
CCTGATGATCGCCTCGCTTCTCACCGACGATACGCTCACGCTGGAAAACGTGCCCCATCTGGCCGATGTCGAGCAATTGA
TCCGCATCCTGAGCAATCATGGCGTCGATTATTCCGTGAACGGACGTCGCGAACACCAGAACGGCCCCTATTCCCGCACG
ATCCATTTCACCGCCCGCAATATCGTGGACACGACCGCGCCTTATGAGCTCGTTTCCAGGATGCGCGCCAGCTTCTGGGT
TATCGGTCCGCTTCTCGCCCGCATGGGTGAGGCCAATGTTTCGCTGCCCGGCGGCTGCGCCATCGGCACACGTCCCGTGG
ACCTGCTGCTTGATGCCCTGCTGGCGCTCGGCGCGGAAATCGACATTGAAAACGGTTATGCCAAAGCCAAGGCCAGGAAC
GGCCTTGTCGGCGCGCGCTATAAATTCCCCAAGGTTTCGGTCGGCGCCACGCATGTCATGCTGATGGCGGCAACGCTGGC
CAAGGGCGAAACCATCATTGAAAATGCCGCACGCGAACCGGAAGTGGCAAACCTCGCCGACTGTCTCAACGCCATGGGGG
CGAAGATCAGCGGCGCGGGCAGCAGCACGATCCATGTTCAAGGCGTCACCAATCTTTCCGGCGCGCGCGTGCGCATCATC
CCGGACCGTATCGAGGCGGGCACCTATGCCATGGCCGTGGCAATGACCGGCGGCGATGTTCTTCTGGAAGGTGCGCAGGA
AAGCCAGCTTTCCTGTGTGCTTGAAACGCTGCGCCAGGCAGGCGCTGAAATCAACGAGACCAATAGCGGCCTGCGCGTGG
TGCGCAACGGGCACGGCATCCAGCCGGTCGATATCACCACCGATCCCTTCCCCGGCTTCCCGACCGATCTTCAGGCGCAG
TTCATGGGCCTGATGACCCGCGCCAAAGGCACCTCGCACATTACCGAGACCATCTTTGAAAACCGCTTCATGCATGTGCA
GGAACTGGCGCGTCTCGGGGCGAAAATCTCGCTCTCCGGCCAGACCGCAACCGTGGAGGGCGTGGAACGCCTGAAGGGCG
CGCAGGTGATGGCGACGGACCTGCGTGCCTCTGTTTCGCTGGTGATCGCAGGACTTGCAGCCGAAGGCGAAACCATCGTC
AACCGCGTCTATCACCTTGATCGCGGCTTTGAACGGCTGGAGGAAAAGCTTTCGCGCTGCGGCGCGGATGTCAAGCGTAT
CAGCGGCTGA

Upstream 100 bases:

>100_bases
CTTGTAAATTTCATGACGCATCGCCGCCGCGCCTGAAGGGCTGCCGGACTTGGCGCAAATCGATTGCCGGACAAATGCTT
CGGCCCAGAAGGTGAACAGC

Downstream 100 bases:

>100_bases
AAATGAACCGCAAATGGCCGGAAATCTTCTCCGGCCTTTTCATTGGCTGCATCATCGTGCACAAGGCTTGAAAAGCCTGT
CGATTTTTTTGCGCCGCCAT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MDRIKIVGGNKLNGVIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILSNHGVDYSVNGRREHQNGPYSRT
IHFTARNIVDTTAPYELVSRMRASFWVIGPLLARMGEANVSLPGGCAIGTRPVDLLLDALLALGAEIDIENGYAKAKARN
GLVGARYKFPKVSVGATHVMLMAATLAKGETIIENAAREPEVANLADCLNAMGAKISGAGSSTIHVQGVTNLSGARVRII
PDRIEAGTYAMAVAMTGGDVLLEGAQESQLSCVLETLRQAGAEINETNSGLRVVRNGHGIQPVDITTDPFPGFPTDLQAQ
FMGLMTRAKGTSHITETIFENRFMHVQELARLGAKISLSGQTATVEGVERLKGAQVMATDLRASVSLVIAGLAAEGETIV
NRVYHLDRGFERLEEKLSRCGADVKRISG

Sequences:

>Translated_429_residues
MDRIKIVGGNKLNGVIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILSNHGVDYSVNGRREHQNGPYSRT
IHFTARNIVDTTAPYELVSRMRASFWVIGPLLARMGEANVSLPGGCAIGTRPVDLLLDALLALGAEIDIENGYAKAKARN
GLVGARYKFPKVSVGATHVMLMAATLAKGETIIENAAREPEVANLADCLNAMGAKISGAGSSTIHVQGVTNLSGARVRII
PDRIEAGTYAMAVAMTGGDVLLEGAQESQLSCVLETLRQAGAEINETNSGLRVVRNGHGIQPVDITTDPFPGFPTDLQAQ
FMGLMTRAKGTSHITETIFENRFMHVQELARLGAKISLSGQTATVEGVERLKGAQVMATDLRASVSLVIAGLAAEGETIV
NRVYHLDRGFERLEEKLSRCGADVKRISG
>Mature_429_residues
MDRIKIVGGNKLNGVIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILSNHGVDYSVNGRREHQNGPYSRT
IHFTARNIVDTTAPYELVSRMRASFWVIGPLLARMGEANVSLPGGCAIGTRPVDLLLDALLALGAEIDIENGYAKAKARN
GLVGARYKFPKVSVGATHVMLMAATLAKGETIIENAAREPEVANLADCLNAMGAKISGAGSSTIHVQGVTNLSGARVRII
PDRIEAGTYAMAVAMTGGDVLLEGAQESQLSCVLETLRQAGAEINETNSGLRVVRNGHGIQPVDITTDPFPGFPTDLQAQ
FMGLMTRAKGTSHITETIFENRFMHVQELARLGAKISLSGQTATVEGVERLKGAQVMATDLRASVSLVIAGLAAEGETIV
NRVYHLDRGFERLEEKLSRCGADVKRISG

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=429, Percent_Identity=49.4172494172494, Blast_Score=413, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_BRUA1 (B2S906)

Other databases:

- EMBL:   CP000887
- RefSeq:   YP_001934279.1
- ProteinModelPortal:   B2S906
- SMR:   B2S906
- GeneID:   6328203
- GenomeReviews:   CP000887_GR
- KEGG:   bmc:BAbS19_I02620
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 45720; Mature: 45720

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: ACT_SITE 126-126

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRIKIVGGNKLNGVIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILSNH
CCCEEEECCCCCCCEEEECCCCCCHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHC
GVDYSVNGRREHQNGPYSRTIHFTARNIVDTTAPYELVSRMRASFWVIGPLLARMGEANV
CCCEEECCCCCCCCCCCEEEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
SLPGGCAIGTRPVDLLLDALLALGAEIDIENGYAKAKARNGLVGARYKFPKVSVGATHVM
CCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHCCCCEECEEECCCCCCCHHHHH
LMAATLAKGETIIENAAREPEVANLADCLNAMGAKISGAGSSTIHVQGVTNLSGARVRII
HHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEEEECCCCCCEEEEE
PDRIEAGTYAMAVAMTGGDVLLEGAQESQLSCVLETLRQAGAEINETNSGLRVVRNGHGI
CCCCCCCCEEEEEEEECCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCC
QPVDITTDPFPGFPTDLQAQFMGLMTRAKGTSHITETIFENRFMHVQELARLGAKISLSG
CEEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECC
QTATVEGVERLKGAQVMATDLRASVSLVIAGLAAEGETIVNRVYHLDRGFERLEEKLSRC
CCCHHHHHHHHCCCCEEHHHHHHHEEHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GADVKRISG
CCHHHHCCC
>Mature Secondary Structure
MDRIKIVGGNKLNGVIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILSNH
CCCEEEECCCCCCCEEEECCCCCCHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHC
GVDYSVNGRREHQNGPYSRTIHFTARNIVDTTAPYELVSRMRASFWVIGPLLARMGEANV
CCCEEECCCCCCCCCCCEEEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
SLPGGCAIGTRPVDLLLDALLALGAEIDIENGYAKAKARNGLVGARYKFPKVSVGATHVM
CCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHCCCCEECEEECCCCCCCHHHHH
LMAATLAKGETIIENAAREPEVANLADCLNAMGAKISGAGSSTIHVQGVTNLSGARVRII
HHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEEEECCCCCCEEEEE
PDRIEAGTYAMAVAMTGGDVLLEGAQESQLSCVLETLRQAGAEINETNSGLRVVRNGHGI
CCCCCCCCEEEEEEEECCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCC
QPVDITTDPFPGFPTDLQAQFMGLMTRAKGTSHITETIFENRFMHVQELARLGAKISLSG
CEEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECC
QTATVEGVERLKGAQVMATDLRASVSLVIAGLAAEGETIVNRVYHLDRGFERLEEKLSRC
CCCHHHHHHHHCCCCEEHHHHHHHEEHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GADVKRISG
CCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA