Definition Brucella melitensis ATCC 23457 chromosome chromosome I, complete sequence.
Accession NC_012441
Length 2,125,701

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The map label for this gene is infA [H]

Identifier: 225851801

GI number: 225851801

Start: 281041

End: 281259

Strand: Reverse

Name: infA [H]

Synonym: BMEA_A0284

Alternate gene names: 225851801

Gene position: 281259-281041 (Counterclockwise)

Preceding gene: 225851802

Following gene: 225851800

Centisome position: 13.23

GC content: 52.05

Gene sequence:

>219_bases
ATGGCGAAAGAAGAAGTCCTCGAATTTCCGGGTGTTGTTACGGAACTGCTGCCCAATGCAATGTTCCGCGTAAAGCTCGA
AAACGAACATGAAATCATTGCCCATACGGCAGGCCGCATGCGCAAGAACCGTATCCGTGTTCTGGCCGGTGACAAGGTTC
TGGTCGAAATGACCCCTTATGACCTGACCAAGGGCCGCATCACCTACCGCTTCAAGTAA

Upstream 100 bases:

>100_bases
TCGTTGTTCACAAATGCCGCCTAATCATATAGGTTCCGCCCAAATTAAGGGCCGAAGCTTTTATTCGGCGGCTTTTATCA
AAGAAAGAAACAGGTATCGC

Downstream 100 bases:

>100_bases
GCATCACTTCCCGTTTCAGGAAATGTCTTGTCGATGAACGTGCAACACAAGCTGGTTCTTGCCTCCGGCTCTCCTCGCAG
GATCGAGCTTCTGGGGCAGG

Product: translation initiation factor IF-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 72; Mature: 71

Protein sequence:

>72_residues
MAKEEVLEFPGVVTELLPNAMFRVKLENEHEIIAHTAGRMRKNRIRVLAGDKVLVEMTPYDLTKGRITYRFK

Sequences:

>Translated_72_residues
MAKEEVLEFPGVVTELLPNAMFRVKLENEHEIIAHTAGRMRKNRIRVLAGDKVLVEMTPYDLTKGRITYRFK
>Mature_71_residues
AKEEVLEFPGVVTELLPNAMFRVKLENEHEIIAHTAGRMRKNRIRVLAGDKVLVEMTPYDLTKGRITYRFK

Specific function: No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 [H]

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787110, Length=70, Percent_Identity=64.2857142857143, Blast_Score=99, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR022967
- InterPro:   IPR006196
- InterPro:   IPR004368 [H]

Pfam domain/function: PF01176 eIF-1a [H]

EC number: NA

Molecular weight: Translated: 8372; Mature: 8241

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKEEVLEFPGVVTELLPNAMFRVKLENEHEIIAHTAGRMRKNRIRVLAGDKVLVEMTPY
CCCHHHHHCCCHHHHHCCCCEEEEEECCCCEEEEECCCCCCCCEEEEEECCEEEEEECCC
DLTKGRITYRFK
CCCCCEEEEEEC
>Mature Secondary Structure 
AKEEVLEFPGVVTELLPNAMFRVKLENEHEIIAHTAGRMRKNRIRVLAGDKVLVEMTPY
CCHHHHHCCCHHHHHCCCCEEEEEECCCCEEEEECCCCCCCCEEEEEECCEEEEEECCC
DLTKGRITYRFK
CCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]