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The map label for this gene is ftsK [H]

Identifier: 225686322

GI number: 225686322

Start: 488470

End: 490935

Strand: Reverse

Name: ftsK [H]

Synonym: BMEA_B0504

Alternate gene names: 225686322

Gene position: 490935-488470 (Counterclockwise)

Preceding gene: 225686323

Following gene: 225686320

Centisome position: 41.41

GC content: 59.98

Gene sequence:

>2466_bases
ATGCGTAATTTGAGAGAAAATTTCCCATATTCCAACGGAAATCGTGTTGAAAACGCCTCGGACCCGAAGCTGCAACGCGG
GCAGGCGGAAGCGCAGAATCCTGCAAGCGACGGCGCCTGGAAGATTCATTTCTCACTGGGTGAAAATGTCCGTTTCACCC
GCACCCCCGAAGTGGAATTGATGCGCCGCCGTGGTGAAGTTCTGCCTGACGTCAATGAACAGCACCCCCGCGCCGAGGCG
CCGGTCCCTGCCGTGGATGTAAAGAAGGCTGCGCAAGCTCAGCCCATGGCTGTAGCCGCTCTTCAGAAAACCGTGTCGCA
GAACATGGTCCGCACGCCTGTCGCCCCTGTACCGCCTGTCATTCCATCTGCTCCGGCTTCTGTTGCCCCGACCGTGGACA
ATGAGCCTCGTCAGGCCGCTTCTGCTGCGCCTGCGACTACAACCACAACCACAACGCAAACACCTGTTCCCGCGTTTGCC
TATCTGTCCGATTCCGCCTTCTGGGAAGGCTGTGATATCGACATCGCCTTGATGCCCTCCACGCTGGTTGTGGCCGCAGT
CCCGGCGGAGCCGCGCAAGCCTGCGCCAAGCGTCGAATCCATTCTGGCGCGCTTTCGCGTTCGCGAATGGCAAAAGCCGC
AGGAAGAAACGCCGGTAGCAGTCGTCGCACCACAGCCCGTCCAGCCGATTGCAGAAACGGCCAAACCGGTTGCCGCAGAA
CCTTTTGTGGAAGAGCCGGCGGCGCCTGCCGTCGAAATGGCGGTGGCACAGGGTGAATCTACCGAGGACGAAGTGGTTCT
GAGCGTCGCGGAAGCGGAAGAGCATGAGGCCGAGGAAGTAGCAGCGCCTGCGGCTATTGTCGAAGCACCCGCTCCGGTGA
AAGCCGCGCCGTCCATCGCGCTTTACCAGCCGCAGCCCCTCCCCCGTGCGGAAACGCCGGTGATTTTCGGCGCCTATGAG
TTTCCGCCGCGCGCACTGCTGCAAGAGCCGCCATCACTGGAAGGCAATGTCATTACGCAGGAGATGCTGGAGCGTAGCGC
CGGGCTTCTCGAAAGTGTGCTGGAAGATTTTGGCGTACGCGGCGAGATCATCCATGTCCGCCCGGGACCGGTCGTCACGC
TCTATGAATTCGAGCCTGCTCCGGGCGTGAAGTCCTCCCGCGTTATCGGCCTTGCGGATGATATCGCTCGCTCCATGTCG
GCGCTTTCAGCCCGCGTGGCCGTGGTTCCGGGCCGTAACGTGATCGGCATCGAACTGCCGAACGCCAATCGTGAAACCGT
TTACCTGCGCGAAATGATCGACTCCCGCGCTTTCGAGTCGTCCAATTATCGCCTGCCGCTTTGCCTCGGCAAAGGTATCG
GCGGTGAGCCGATCATCGCTGAGCTTGCCAAGATGCCCCATCTTCTGGTGGCGGGCACCACGGGTTCGGGCAAGTCAGTT
GCGATCAACACCATGATCCTGTCGCTGCTTTACCGCTTCAAGCCGGAAGAATGCCGCCTGATCATGGTCGATCCGAAGAT
GCTGGAACTATCGATCTATGACGGCATCCCGCATCTGCTTACGCCAGTTGTGACCGATCCGAAAAAGGCGGTCGTGGCGC
TGAAATGGGCTGTGCGCGAGATGGAAGACCGCTATCGCAAGATGGCTCGCCTTGGTGTGCGCAACATCGAGGGTTTCAAT
CAGCGCGCCGCATCGGCCAAGGGCAAGGGCGAAACCGTGATGTGCACGGTGCAGTCCGGCTTTGACAAGGAAACGGGCGA
GCCGACCTATATTCAGGAAGAACTCGACCTGACGCCAATGCCCTATATCGTCGTCATCATCGACGAAATGGCCGACCTGA
TGATGGTTGCTGGCAAGGACATTGAAGGTGCCGTACAGCGTCTTGCCCAGATGGCCCGTGCAGCCGGTATCCATCTCATC
ATGGCGACGCAGCGCCCGTCGGTCGATGTCATCACCGGCACGATCAAGGCGAATTTCCCGACCCGTATTTCGTTCCAGGT
TACATCCAAGATCGACAGCCGCACCATCCTTGGCGAAATGGGTGCTGAACAGCTTCTCGGTCAGGGCGACATGCTGCATA
TGGCTGGCGGCGGACGCATCGTCCGTGTTCACGGCCCCTTCGTTTCCGATGAGGAAGTGGAAAAGGTCGTCAATCATCTG
AAGGAACAGGGCCGCCCGGATTATCTGGCAACGGTGACCGAGGATGAGGAAGAAGAAGATGTCGCGGCCGAACCGGCAGT
CTTCGACAACACGGCCATGGGTGGGGAAGACGGCGAAGACGTCTATGAGCAGGCCGTAAAAGTGGTGATGCGCGACAAGA
AGTGCTCCACCTCCTATATCCAGCGCCGCCTCGGCATCGGTTACAACCGCGCGGCGTCATTGGTCGAGCGGATGGAGAAG
GAAGGCCTTGTCGGCCCGGCGAACCACGTCGGCAAGCGCGAGATCCTGACAGGCCAGCGCGACTGA

Upstream 100 bases:

>100_bases
AGAAATTTATCGTTTTTTGGCGCTTTCGGAAGGGGGTTGTTAACCTTCATTTTTTATTACTTGGGCTCATTCAGGCGATC
GTATCTATGGTTCAGGTATC

Downstream 100 bases:

>100_bases
TCCCCGCAATATGGAATGCAAGAAAAGCCGGGTCTCGCGCCCGGCTTTTCGCTGTCATTCTATAGGCTTGCTATGGGCTT
GACTGGAACGATCAGGCCGG

Product: DNA translocase ftsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 821; Mature: 821

Protein sequence:

>821_residues
MRNLRENFPYSNGNRVENASDPKLQRGQAEAQNPASDGAWKIHFSLGENVRFTRTPEVELMRRRGEVLPDVNEQHPRAEA
PVPAVDVKKAAQAQPMAVAALQKTVSQNMVRTPVAPVPPVIPSAPASVAPTVDNEPRQAASAAPATTTTTTTQTPVPAFA
YLSDSAFWEGCDIDIALMPSTLVVAAVPAEPRKPAPSVESILARFRVREWQKPQEETPVAVVAPQPVQPIAETAKPVAAE
PFVEEPAAPAVEMAVAQGESTEDEVVLSVAEAEEHEAEEVAAPAAIVEAPAPVKAAPSIALYQPQPLPRAETPVIFGAYE
FPPRALLQEPPSLEGNVITQEMLERSAGLLESVLEDFGVRGEIIHVRPGPVVTLYEFEPAPGVKSSRVIGLADDIARSMS
ALSARVAVVPGRNVIGIELPNANRETVYLREMIDSRAFESSNYRLPLCLGKGIGGEPIIAELAKMPHLLVAGTTGSGKSV
AINTMILSLLYRFKPEECRLIMVDPKMLELSIYDGIPHLLTPVVTDPKKAVVALKWAVREMEDRYRKMARLGVRNIEGFN
QRAASAKGKGETVMCTVQSGFDKETGEPTYIQEELDLTPMPYIVVIIDEMADLMMVAGKDIEGAVQRLAQMARAAGIHLI
MATQRPSVDVITGTIKANFPTRISFQVTSKIDSRTILGEMGAEQLLGQGDMLHMAGGGRIVRVHGPFVSDEEVEKVVNHL
KEQGRPDYLATVTEDEEEEDVAAEPAVFDNTAMGGEDGEDVYEQAVKVVMRDKKCSTSYIQRRLGIGYNRAASLVERMEK
EGLVGPANHVGKREILTGQRD

Sequences:

>Translated_821_residues
MRNLRENFPYSNGNRVENASDPKLQRGQAEAQNPASDGAWKIHFSLGENVRFTRTPEVELMRRRGEVLPDVNEQHPRAEA
PVPAVDVKKAAQAQPMAVAALQKTVSQNMVRTPVAPVPPVIPSAPASVAPTVDNEPRQAASAAPATTTTTTTQTPVPAFA
YLSDSAFWEGCDIDIALMPSTLVVAAVPAEPRKPAPSVESILARFRVREWQKPQEETPVAVVAPQPVQPIAETAKPVAAE
PFVEEPAAPAVEMAVAQGESTEDEVVLSVAEAEEHEAEEVAAPAAIVEAPAPVKAAPSIALYQPQPLPRAETPVIFGAYE
FPPRALLQEPPSLEGNVITQEMLERSAGLLESVLEDFGVRGEIIHVRPGPVVTLYEFEPAPGVKSSRVIGLADDIARSMS
ALSARVAVVPGRNVIGIELPNANRETVYLREMIDSRAFESSNYRLPLCLGKGIGGEPIIAELAKMPHLLVAGTTGSGKSV
AINTMILSLLYRFKPEECRLIMVDPKMLELSIYDGIPHLLTPVVTDPKKAVVALKWAVREMEDRYRKMARLGVRNIEGFN
QRAASAKGKGETVMCTVQSGFDKETGEPTYIQEELDLTPMPYIVVIIDEMADLMMVAGKDIEGAVQRLAQMARAAGIHLI
MATQRPSVDVITGTIKANFPTRISFQVTSKIDSRTILGEMGAEQLLGQGDMLHMAGGGRIVRVHGPFVSDEEVEKVVNHL
KEQGRPDYLATVTEDEEEEDVAAEPAVFDNTAMGGEDGEDVYEQAVKVVMRDKKCSTSYIQRRLGIGYNRAASLVERMEK
EGLVGPANHVGKREILTGQRD
>Mature_821_residues
MRNLRENFPYSNGNRVENASDPKLQRGQAEAQNPASDGAWKIHFSLGENVRFTRTPEVELMRRRGEVLPDVNEQHPRAEA
PVPAVDVKKAAQAQPMAVAALQKTVSQNMVRTPVAPVPPVIPSAPASVAPTVDNEPRQAASAAPATTTTTTTQTPVPAFA
YLSDSAFWEGCDIDIALMPSTLVVAAVPAEPRKPAPSVESILARFRVREWQKPQEETPVAVVAPQPVQPIAETAKPVAAE
PFVEEPAAPAVEMAVAQGESTEDEVVLSVAEAEEHEAEEVAAPAAIVEAPAPVKAAPSIALYQPQPLPRAETPVIFGAYE
FPPRALLQEPPSLEGNVITQEMLERSAGLLESVLEDFGVRGEIIHVRPGPVVTLYEFEPAPGVKSSRVIGLADDIARSMS
ALSARVAVVPGRNVIGIELPNANRETVYLREMIDSRAFESSNYRLPLCLGKGIGGEPIIAELAKMPHLLVAGTTGSGKSV
AINTMILSLLYRFKPEECRLIMVDPKMLELSIYDGIPHLLTPVVTDPKKAVVALKWAVREMEDRYRKMARLGVRNIEGFN
QRAASAKGKGETVMCTVQSGFDKETGEPTYIQEELDLTPMPYIVVIIDEMADLMMVAGKDIEGAVQRLAQMARAAGIHLI
MATQRPSVDVITGTIKANFPTRISFQVTSKIDSRTILGEMGAEQLLGQGDMLHMAGGGRIVRVHGPFVSDEEVEKVVNHL
KEQGRPDYLATVTEDEEEEDVAAEPAVFDNTAMGGEDGEDVYEQAVKVVMRDKKCSTSYIQRRLGIGYNRAASLVERMEK
EGLVGPANHVGKREILTGQRD

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=514, Percent_Identity=50.9727626459144, Blast_Score=488, Evalue=1e-139,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 88983; Mature: 88983

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNLRENFPYSNGNRVENASDPKLQRGQAEAQNPASDGAWKIHFSLGENVRFTRTPEVEL
CCCCHHHCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCEEEEEEECCCCEEEECCCHHHH
MRRRGEVLPDVNEQHPRAEAPVPAVDVKKAAQAQPMAVAALQKTVSQNMVRTPVAPVPPV
HHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
IPSAPASVAPTVDNEPRQAASAAPATTTTTTTQTPVPAFAYLSDSAFWEGCDIDIALMPS
CCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEECCC
TLVVAAVPAEPRKPAPSVESILARFRVREWQKPQEETPVAVVAPQPVQPIAETAKPVAAE
EEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHCCEEEECCCCCHHHHHHCCCCCCC
PFVEEPAAPAVEMAVAQGESTEDEVVLSVAEAEEHEAEEVAAPAAIVEAPAPVKAAPSIA
CCCCCCCCCHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHCCHHHCCCCCCCCCCCCEE
LYQPQPLPRAETPVIFGAYEFPPRALLQEPPSLEGNVITQEMLERSAGLLESVLEDFGVR
EECCCCCCCCCCCEEEEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
GEIIHVRPGPVVTLYEFEPAPGVKSSRVIGLADDIARSMSALSARVAVVPGRNVIGIELP
CEEEEECCCCEEEEEEECCCCCCCCCEEEECHHHHHHHHHHHHEEEEEECCCCEEEEECC
NANRETVYLREMIDSRAFESSNYRLPLCLGKGIGGEPIIAELAKMPHLLVAGTTGSGKSV
CCCCCEEHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHCCEEEEEECCCCCCEE
AINTMILSLLYRFKPEECRLIMVDPKMLELSIYDGIPHLLTPVVTDPKKAVVALKWAVRE
HHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCCHHHHCCCCCCCHHHHHHHHHHHHH
MEDRYRKMARLGVRNIEGFNQRAASAKGKGETVMCTVQSGFDKETGEPTYIQEELDLTPM
HHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCEEHHCCCCCCC
PYIVVIIDEMADLMMVAGKDIEGAVQRLAQMARAAGIHLIMATQRPSVDVITGTIKANFP
CEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEEEECCC
TRISFQVTSKIDSRTILGEMGAEQLLGQGDMLHMAGGGRIVRVHGPFVSDEEVEKVVNHL
CEEEEEEECCCCCHHHHHHHCHHHHHCCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHH
KEQGRPDYLATVTEDEEEEDVAAEPAVFDNTAMGGEDGEDVYEQAVKVVMRDKKCSTSYI
HHCCCCCEEEEECCCCCCHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHH
QRRLGIGYNRAASLVERMEKEGLVGPANHVGKREILTGQRD
HHHHCCCHHHHHHHHHHHHHCCCCCCHHHCCCHHCCCCCCC
>Mature Secondary Structure
MRNLRENFPYSNGNRVENASDPKLQRGQAEAQNPASDGAWKIHFSLGENVRFTRTPEVEL
CCCCHHHCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCEEEEEEECCCCEEEECCCHHHH
MRRRGEVLPDVNEQHPRAEAPVPAVDVKKAAQAQPMAVAALQKTVSQNMVRTPVAPVPPV
HHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
IPSAPASVAPTVDNEPRQAASAAPATTTTTTTQTPVPAFAYLSDSAFWEGCDIDIALMPS
CCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEECCC
TLVVAAVPAEPRKPAPSVESILARFRVREWQKPQEETPVAVVAPQPVQPIAETAKPVAAE
EEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHCCEEEECCCCCHHHHHHCCCCCCC
PFVEEPAAPAVEMAVAQGESTEDEVVLSVAEAEEHEAEEVAAPAAIVEAPAPVKAAPSIA
CCCCCCCCCHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHCCHHHCCCCCCCCCCCCEE
LYQPQPLPRAETPVIFGAYEFPPRALLQEPPSLEGNVITQEMLERSAGLLESVLEDFGVR
EECCCCCCCCCCCEEEEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
GEIIHVRPGPVVTLYEFEPAPGVKSSRVIGLADDIARSMSALSARVAVVPGRNVIGIELP
CEEEEECCCCEEEEEEECCCCCCCCCEEEECHHHHHHHHHHHHEEEEEECCCCEEEEECC
NANRETVYLREMIDSRAFESSNYRLPLCLGKGIGGEPIIAELAKMPHLLVAGTTGSGKSV
CCCCCEEHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHCCEEEEEECCCCCCEE
AINTMILSLLYRFKPEECRLIMVDPKMLELSIYDGIPHLLTPVVTDPKKAVVALKWAVRE
HHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCCHHHHCCCCCCCHHHHHHHHHHHHH
MEDRYRKMARLGVRNIEGFNQRAASAKGKGETVMCTVQSGFDKETGEPTYIQEELDLTPM
HHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCEEHHCCCCCCC
PYIVVIIDEMADLMMVAGKDIEGAVQRLAQMARAAGIHLIMATQRPSVDVITGTIKANFP
CEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEEEECCC
TRISFQVTSKIDSRTILGEMGAEQLLGQGDMLHMAGGGRIVRVHGPFVSDEEVEKVVNHL
CEEEEEEECCCCCHHHHHHHCHHHHHCCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHH
KEQGRPDYLATVTEDEEEEDVAAEPAVFDNTAMGGEDGEDVYEQAVKVVMRDKKCSTSYI
HHCCCCCEEEEECCCCCCHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHH
QRRLGIGYNRAASLVERMEKEGLVGPANHVGKREILTGQRD
HHHHCCCHHHHHHHHHHHHHCCCCCCHHHCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]