Click here to switch to the map view.

The map label for this gene is lldR [H]

Identifier: 225686220

GI number: 225686220

Start: 374388

End: 375116

Strand: Reverse

Name: lldR [H]

Synonym: BMEA_B0388

Alternate gene names: 225686220

Gene position: 375116-374388 (Counterclockwise)

Preceding gene: 225686224

Following gene: 225686219

Centisome position: 31.64

GC content: 57.34

Gene sequence:

>729_bases
ATGAAAAATCCGATCAAGCCCCTGAAACGCGCGCCTCTGTTGCACGTATCGGTTCAGGAAAGCCTGCGTGCCTATATCGA
GGATAATGGCCTTCAGGCAGGTGCGCCCCTTCCGCCGGAAGGCGAGCTTGCCGCCCGGCTCGGTGTTAGCCGCAATTCCG
TGCGCGAGGCGATCAAGGCGCTGGAATCGGTAGGCGTGCTTGAATCGCGCCGCGGCATTGGCGTTTTCGTGAAAGCTTTC
TCTTTCGAGCCATTGCTGGAAAATCTGGCCTATGGGCTCGGCGGCGCCTTGCGCCAGATCGAGGAAGTGATCGCCATTCG
GCGCGCGCTGGAAATCGGCCTTATCGACAAAACGCTGGAGCGGATTGGCGAAGACGACATCAAGGAGCTGCGCGACACGC
TGGAGAAGATGCGCCAGCGCGCCGAACGCGGCGAAGGTTTTCCTGAAGAGGACAGGCACTTTCACCAGTTACTGTTCCGC
TGTCAGGACAATGAAGTGCTGCTCCGGCTGATCGAAGTGTTCTGGCTTGCCTTCTACAAGGCGTCCGACTTTGTGAATCT
GGAAAATATCGATCCGATGGCGACATGGCGCGATCATGTCGCCATCGTGGATGCAATCGAAGCACGCGATGTGGTTGCAG
TGCGCAAGCAACTCGACCGCCACTATTCGGGTATCAATCAGGTGATTGCCCGAAACAGAACAGCTTCGTTGACTGGGAGG
AAGACATGA

Upstream 100 bases:

>100_bases
TAACGGACGTCTAAATATCCTATTGACAGATATCCTACAAGTGAATAATTAATGGCGATCTGCTCAATCGGAGTCCCGCA
TGCCTAAACCGGAGACGAAG

Downstream 100 bases:

>100_bases
GGTTGCGTAATTTTTATTCGGCGCTTGCCTTGTCGGCAGCGGTTTTCGCCGGGCCACTCTATGCTGCGGCACCGGCCATG
GCTGCGGGCACGATTTCGGG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MKNPIKPLKRAPLLHVSVQESLRAYIEDNGLQAGAPLPPEGELAARLGVSRNSVREAIKALESVGVLESRRGIGVFVKAF
SFEPLLENLAYGLGGALRQIEEVIAIRRALEIGLIDKTLERIGEDDIKELRDTLEKMRQRAERGEGFPEEDRHFHQLLFR
CQDNEVLLRLIEVFWLAFYKASDFVNLENIDPMATWRDHVAIVDAIEARDVVAVRKQLDRHYSGINQVIARNRTASLTGR
KT

Sequences:

>Translated_242_residues
MKNPIKPLKRAPLLHVSVQESLRAYIEDNGLQAGAPLPPEGELAARLGVSRNSVREAIKALESVGVLESRRGIGVFVKAF
SFEPLLENLAYGLGGALRQIEEVIAIRRALEIGLIDKTLERIGEDDIKELRDTLEKMRQRAERGEGFPEEDRHFHQLLFR
CQDNEVLLRLIEVFWLAFYKASDFVNLENIDPMATWRDHVAIVDAIEARDVVAVRKQLDRHYSGINQVIARNRTASLTGR
KT
>Mature_242_residues
MKNPIKPLKRAPLLHVSVQESLRAYIEDNGLQAGAPLPPEGELAARLGVSRNSVREAIKALESVGVLESRRGIGVFVKAF
SFEPLLENLAYGLGGALRQIEEVIAIRRALEIGLIDKTLERIGEDDIKELRDTLEKMRQRAERGEGFPEEDRHFHQLLFR
CQDNEVLLRLIEVFWLAFYKASDFVNLENIDPMATWRDHVAIVDAIEARDVVAVRKQLDRHYSGINQVIARNRTASLTGR
KT

Specific function: May be a regulatory protein for the LCT genes [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790032, Length=222, Percent_Identity=28.3783783783784, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787821, Length=230, Percent_Identity=26.0869565217391, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27401; Mature: 27401

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNPIKPLKRAPLLHVSVQESLRAYIEDNGLQAGAPLPPEGELAARLGVSRNSVREAIKA
CCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHH
LESVGVLESRRGIGVFVKAFSFEPLLENLAYGLGGALRQIEEVIAIRRALEIGLIDKTLE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIGEDDIKELRDTLEKMRQRAERGEGFPEEDRHFHQLLFRCQDNEVLLRLIEVFWLAFYK
HHCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ASDFVNLENIDPMATWRDHVAIVDAIEARDVVAVRKQLDRHYSGINQVIARNRTASLTGR
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
KT
CC
>Mature Secondary Structure
MKNPIKPLKRAPLLHVSVQESLRAYIEDNGLQAGAPLPPEGELAARLGVSRNSVREAIKA
CCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHH
LESVGVLESRRGIGVFVKAFSFEPLLENLAYGLGGALRQIEEVIAIRRALEIGLIDKTLE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIGEDDIKELRDTLEKMRQRAERGEGFPEEDRHFHQLLFRCQDNEVLLRLIEVFWLAFYK
HHCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ASDFVNLENIDPMATWRDHVAIVDAIEARDVVAVRKQLDRHYSGINQVIARNRTASLTGR
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
KT
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407843; 8041620; 9278503 [H]