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The map label for this gene is oxyR [H]

Identifier: 225686189

GI number: 225686189

Start: 334633

End: 335586

Strand: Reverse

Name: oxyR [H]

Synonym: BMEA_B0353

Alternate gene names: 225686189

Gene position: 335586-334633 (Counterclockwise)

Preceding gene: 225686200

Following gene: 225686188

Centisome position: 28.31

GC content: 55.56

Gene sequence:

>954_bases
ATGTTTACAGTCCGTCAAATACGCTATTTCGATGCGCTTGCCTCTACCCTGCATTTTCGCAAGGCCGCCGAACTGGCCCA
TGTTTCACAACCAGCACTCTCCGCCCAGATTGCAGAAATGGAGGCAATCGCCGGTGCACCGCTTTTCGAGCGCTCGCAGC
GGCAGGTTATCATGACCGAGCTTGGAAAGCACCTTTATCCTGGCATCAAGGCCATCCTGCGCGAATTACAGAAGCTGGAG
GAAATAGCCGCACAAAGCCGTGGCCTGCTGCAAACGGGCATAAAGCTCGGGATCATTCCCACCGTCGCGCCCTATCTCGT
GCCGGTTCTCATTCCCCTGCTGCACGAACAGCATCCATCTTTCCGCCTACAGTTGCGCGAGAGCGTCACGGCAAAATTGC
TGGAAGAACTGCACGCTGGCGATCTGGACGCCATTGTTGCCGCCTTGCCGATCGATGACGAGAAGCTTAGCCACCAGAAG
CTTTTCGACGACCGTTTTCTCATCGCCACCTCCACCAACGACCATACGGTTCTCGCCTCGCCGATGACGCAGAACCATGC
CGCGCTGGAACGACTTCTGCTGCTGGAGGAAGGCCATTGCATGCGCGACCAGGCGCTCGCCGTTTGCACCCTGCCCTCCC
AGCGGCAACTGGTGAAATACGGCGCAACCAGCATGAGCACGCTTTTGCAGATGGTCAGCCATGGCATGGGGCTGACGCTG
ATCCCCGAAATTGCCGTTCGTGCCGAAGCGCGCAGCAACCATATGCGCATCGTGCCTTTCGAGGGGGAACAACCCAAGCG
CGAGATTGCACTTTTCTGGCGGCGGCAAAGCATGCGCGGGAAAGATTTTCGAGCGCTCGCCGAATGTATTGCAGAAAGTG
CTAATAAACTAAAGATAGATCCTTCCAAGATTGATACTTTATTAGATAACCCTTCTACCCCTTCATATTCTTAA

Upstream 100 bases:

>100_bases
GAAACATCACACCGGGGCGAAACCATTTGTCTCAATTAGACCTATTCCAATAATAATCTCCAATTGCTTTTTTTGTTATT
ATTGATAAGATTTTCCTATC

Downstream 100 bases:

>100_bases
TGTTACATTAAGCCTGAAAGTATAGCCCCCAAATGTTTTGATTCCAAAACACATATATGGAGGGAATAATGAGATGGTCC
GATGTGGGGATCTATGGTGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Morphology and auto-aggregation control protein [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MFTVRQIRYFDALASTLHFRKAAELAHVSQPALSAQIAEMEAIAGAPLFERSQRQVIMTELGKHLYPGIKAILRELQKLE
EIAAQSRGLLQTGIKLGIIPTVAPYLVPVLIPLLHEQHPSFRLQLRESVTAKLLEELHAGDLDAIVAALPIDDEKLSHQK
LFDDRFLIATSTNDHTVLASPMTQNHAALERLLLLEEGHCMRDQALAVCTLPSQRQLVKYGATSMSTLLQMVSHGMGLTL
IPEIAVRAEARSNHMRIVPFEGEQPKREIALFWRRQSMRGKDFRALAECIAESANKLKIDPSKIDTLLDNPSTPSYS

Sequences:

>Translated_317_residues
MFTVRQIRYFDALASTLHFRKAAELAHVSQPALSAQIAEMEAIAGAPLFERSQRQVIMTELGKHLYPGIKAILRELQKLE
EIAAQSRGLLQTGIKLGIIPTVAPYLVPVLIPLLHEQHPSFRLQLRESVTAKLLEELHAGDLDAIVAALPIDDEKLSHQK
LFDDRFLIATSTNDHTVLASPMTQNHAALERLLLLEEGHCMRDQALAVCTLPSQRQLVKYGATSMSTLLQMVSHGMGLTL
IPEIAVRAEARSNHMRIVPFEGEQPKREIALFWRRQSMRGKDFRALAECIAESANKLKIDPSKIDTLLDNPSTPSYS
>Mature_317_residues
MFTVRQIRYFDALASTLHFRKAAELAHVSQPALSAQIAEMEAIAGAPLFERSQRQVIMTELGKHLYPGIKAILRELQKLE
EIAAQSRGLLQTGIKLGIIPTVAPYLVPVLIPLLHEQHPSFRLQLRESVTAKLLEELHAGDLDAIVAALPIDDEKLSHQK
LFDDRFLIATSTNDHTVLASPMTQNHAALERLLLLEEGHCMRDQALAVCTLPSQRQLVKYGATSMSTLLQMVSHGMGLTL
IPEIAVRAEARSNHMRIVPFEGEQPKREIALFWRRQSMRGKDFRALAECIAESANKLKIDPSKIDTLLDNPSTPSYS

Specific function: Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=289, Percent_Identity=37.0242214532872, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1788887, Length=294, Percent_Identity=25.8503401360544, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787601, Length=168, Percent_Identity=32.1428571428571, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI157672245, Length=242, Percent_Identity=28.099173553719, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787879, Length=295, Percent_Identity=29.1525423728814, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI145693105, Length=257, Percent_Identity=24.124513618677, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1788297, Length=252, Percent_Identity=28.968253968254, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI2367136, Length=243, Percent_Identity=30.4526748971193, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87081904, Length=284, Percent_Identity=24.2957746478873, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790783, Length=258, Percent_Identity=26.3565891472868, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788748, Length=309, Percent_Identity=22.6537216828479, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35360; Mature: 35360

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTVRQIRYFDALASTLHFRKAAELAHVSQPALSAQIAEMEAIAGAPLFERSQRQVIMTE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LGKHLYPGIKAILRELQKLEEIAAQSRGLLQTGIKLGIIPTVAPYLVPVLIPLLHEQHPS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHCCHHHHHHHHHHHHHHHHHCCCCC
FRLQLRESVTAKLLEELHAGDLDAIVAALPIDDEKLSHQKLFDDRFLIATSTNDHTVLAS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCEEEEC
PMTQNHAALERLLLLEEGHCMRDQALAVCTLPSQRQLVKYGATSMSTLLQMVSHGMGLTL
CCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHCCHHHHHHHHHHHCCCCEEE
IPEIAVRAEARSNHMRIVPFEGEQPKREIALFWRRQSMRGKDFRALAECIAESANKLKID
HHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEECC
PSKIDTLLDNPSTPSYS
HHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MFTVRQIRYFDALASTLHFRKAAELAHVSQPALSAQIAEMEAIAGAPLFERSQRQVIMTE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LGKHLYPGIKAILRELQKLEEIAAQSRGLLQTGIKLGIIPTVAPYLVPVLIPLLHEQHPS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHCCHHHHHHHHHHHHHHHHHCCCCC
FRLQLRESVTAKLLEELHAGDLDAIVAALPIDDEKLSHQKLFDDRFLIATSTNDHTVLAS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCEEEEC
PMTQNHAALERLLLLEEGHCMRDQALAVCTLPSQRQLVKYGATSMSTLLQMVSHGMGLTL
CCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHCCHHHHHHHHHHHCCCCEEE
IPEIAVRAEARSNHMRIVPFEGEQPKREIALFWRRQSMRGKDFRALAECIAESANKLKID
HHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEECC
PSKIDTLLDNPSTPSYS
HHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]