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The map label for this gene is prsA [H]

Identifier: 225686140

GI number: 225686140

Start: 275356

End: 276291

Strand: Reverse

Name: prsA [H]

Synonym: BMEA_B0296

Alternate gene names: 225686140

Gene position: 276291-275356 (Counterclockwise)

Preceding gene: 225686141

Following gene: 225686139

Centisome position: 23.31

GC content: 63.89

Gene sequence:

>936_bases
ATGGTCACACTTTTCGACCGGAAGAATGCAGGTGGACAACCGGCGGGGGATAACCCCGCCGGACATCACGGCCACCAGCA
CCAGTCCGGCTACACCACCTATCAGGAACCCGATACGCGCGTGCCGCCCAAGCCGCGCCCGGTTTTCGATGCGGTTTCGG
TCAATGGCGTCACGATTGACGAAGCCGATATCCTGACCGAAGCGCAGAACCACCCGGCGGAAAACCCCGGCGCGGCGCTG
CTTTCAGCGGCCCGCGCCCTTGCTGTGCGCGAGCTTCTCCTGCAACGCGCAAGGGAAATCGGCATCGAGCCGGAACATGA
GAAAGACGCCGAAGGCCGCGCCGAAACCGATGAGGATGCGCTTGTGCGCATGGTCATCGAACGGGAAGTGGACGTGCCTT
CTGCCTCCCGCGATGAAGCCCAGCGTTACTATGAGAACAACCGCCATCGCTTCACCAGCGCGCCCATTCTGGAAGCAAGC
CACATTCTGATTGCTGCCGACCCGGCAGATCAGGAGACGCGCGACGCCGCCCGCCAGACGGCCACGCGGCTTGCCGCAGC
CGTCATTGCGGAGCCTGCAACCTTTGCCTCCGTCGCGCTGGAATATTCGTCCTGCCCGTCGGGCGCACAGGGCGGCAATC
TGGGCCAGCTCACACGCGGCAGCACCGTGCCGGAATTCGAGCGGGCGCTGGAGCGGATGACACCCGGCGAAACCACTGCC
AACCCCATCGAAAGCCGTTTCGGCTACCACATCGTCCGGCTGGACCGGCGCGTGGAAGGCGAGGAACTTCCCTTCGATTA
TGTGGCCGACAAGATCGCGGGCTGGCTTGAAGCCTCCACCTGGTCGAAGGCAGTGTCGCAATATATCGCGATCCTTGCCG
CCGAGGCTGAGATTACCGGCATCGACCTTCTGTCCGGCGAGGACGGCGGCGAATGA

Upstream 100 bases:

>100_bases
CGCCGGTGCGTTATATCTGGCGTCCGGGCTATCAGGTGGTGCGTGAGCGCAACCACACCGCCGCGCCTTCGCATCTGCGC
GCTCCTGCGGAGTAAGGTTC

Downstream 100 bases:

>100_bases
AAGCCGCCCCTATCCTCGCTGCAATCCATGCGGCCAAGGACGTGCCTGTTGACCCCCTGCTGGCGGAAATCGCCGCGCGG
GGCAAGCAGGATGGCTTGCG

Product: chaperone SurA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MVTLFDRKNAGGQPAGDNPAGHHGHQHQSGYTTYQEPDTRVPPKPRPVFDAVSVNGVTIDEADILTEAQNHPAENPGAAL
LSAARALAVRELLLQRAREIGIEPEHEKDAEGRAETDEDALVRMVIEREVDVPSASRDEAQRYYENNRHRFTSAPILEAS
HILIAADPADQETRDAARQTATRLAAAVIAEPATFASVALEYSSCPSGAQGGNLGQLTRGSTVPEFERALERMTPGETTA
NPIESRFGYHIVRLDRRVEGEELPFDYVADKIAGWLEASTWSKAVSQYIAILAAEAEITGIDLLSGEDGGE

Sequences:

>Translated_311_residues
MVTLFDRKNAGGQPAGDNPAGHHGHQHQSGYTTYQEPDTRVPPKPRPVFDAVSVNGVTIDEADILTEAQNHPAENPGAAL
LSAARALAVRELLLQRAREIGIEPEHEKDAEGRAETDEDALVRMVIEREVDVPSASRDEAQRYYENNRHRFTSAPILEAS
HILIAADPADQETRDAARQTATRLAAAVIAEPATFASVALEYSSCPSGAQGGNLGQLTRGSTVPEFERALERMTPGETTA
NPIESRFGYHIVRLDRRVEGEELPFDYVADKIAGWLEASTWSKAVSQYIAILAAEAEITGIDLLSGEDGGE
>Mature_311_residues
MVTLFDRKNAGGQPAGDNPAGHHGHQHQSGYTTYQEPDTRVPPKPRPVFDAVSVNGVTIDEADILTEAQNHPAENPGAAL
LSAARALAVRELLLQRAREIGIEPEHEKDAEGRAETDEDALVRMVIEREVDVPSASRDEAQRYYENNRHRFTSAPILEAS
HILIAADPADQETRDAARQTATRLAAAVIAEPATFASVALEYSSCPSGAQGGNLGQLTRGSTVPEFERALERMTPGETTA
NPIESRFGYHIVRLDRRVEGEELPFDYVADKIAGWLEASTWSKAVSQYIAILAAEAEITGIDLLSGEDGGE

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

None

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 33700; Mature: 33700

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTLFDRKNAGGQPAGDNPAGHHGHQHQSGYTTYQEPDTRVPPKPRPVFDAVSVNGVTID
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEC
EADILTEAQNHPAENPGAALLSAARALAVRELLLQRAREIGIEPEHEKDAEGRAETDEDA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHH
LVRMVIEREVDVPSASRDEAQRYYENNRHRFTSAPILEASHILIAADPADQETRDAARQT
HHHHHHHHHCCCCCCCHHHHHHHHHCCCEEECCCCCCCCCEEEEEECCCCHHHHHHHHHH
ATRLAAAVIAEPATFASVALEYSSCPSGAQGGNLGQLTRGSTVPEFERALERMTPGETTA
HHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCC
NPIESRFGYHIVRLDRRVEGEELPFDYVADKIAGWLEASTWSKAVSQYIAILAAEAEITG
CHHHHHHCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
IDLLSGEDGGE
EEEECCCCCCC
>Mature Secondary Structure
MVTLFDRKNAGGQPAGDNPAGHHGHQHQSGYTTYQEPDTRVPPKPRPVFDAVSVNGVTID
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEC
EADILTEAQNHPAENPGAALLSAARALAVRELLLQRAREIGIEPEHEKDAEGRAETDEDA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHH
LVRMVIEREVDVPSASRDEAQRYYENNRHRFTSAPILEASHILIAADPADQETRDAARQT
HHHHHHHHHCCCCCCCHHHHHHHHHCCCEEECCCCCCCCCEEEEEECCCCHHHHHHHHHH
ATRLAAAVIAEPATFASVALEYSSCPSGAQGGNLGQLTRGSTVPEFERALERMTPGETTA
HHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCC
NPIESRFGYHIVRLDRRVEGEELPFDYVADKIAGWLEASTWSKAVSQYIAILAAEAEITG
CHHHHHHCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
IDLLSGEDGGE
EEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]