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The map label for this gene is yciL [C]

Identifier: 225686060

GI number: 225686060

Start: 189020

End: 190816

Strand: Direct

Name: yciL [C]

Synonym: BMEA_B0205

Alternate gene names: 225686060

Gene position: 189020-190816 (Clockwise)

Preceding gene: 225686058

Following gene: 225686061

Centisome position: 15.94

GC content: 64.0

Gene sequence:

>1797_bases
TTGCGAACGGAATTATACGGCGTTCCTGTTGCGAATAACCTTTGGCGTGCAATGATGGCGCAAGGTGACGCGGTAACGCT
GCTGAAAGGCCTATATCAGATGACCACAGAAGACGACAACAAGGGCGGGAAGCCCCCTCATGGCCGCAAAGGGCATTCAG
ATCGCCCTGGCCGCCCTGACTGGGACAGCCGCCCGCGCCGCGAAGGCGGCGACCGCGACAAGCCTCGTAAATTCGGTTCC
AGGGGCGCGCCGGTCGAAGAGGAGACGAGCGAGCGGATAGCCAAGCGTCTGGCGCGCGCGGGCATTGCCTCGCGCCGCGA
GGCGGAAACGATGATTGCTGCCGGGCGCATTGCGGTTAATGGCAAGGTGCTGGAAAGCCCCGCCGTCAATGTAAAGCGCA
CCGACATCATCACCGTCGACGGCAAGCCGTTGAGGCAGACGGAGCGCACCCGCCTGTGGCTCTATCACAAGCCCGCCGGT
CTCGTGACCACCAATCGCGACCCGGAGGGCCGCCCGACGGTTTTCGAGGCCCTGCCGCCGGAAATGCCACGCGTATTGTC
GGTCGGGCGTCTTGATATCAACACGGAAGGCCTTCTGCTCCTTACCAATGATGGCGGGCTGTCGCGCGTTCTGGAACTGC
CCTCCACGGGTTGGTTGCGCCGCTATCGCGTGCGCGCGCATGGCAAGGTCACGCGGCAGCAGCTTGATGAATTGAAAAAC
GGCATCGCGGTCGATGGCGTTTTTTATGGCAGCGTGGAAGCCGAGCTTGAGCGCGTTCAGGGCGCGAATGTCTGGATTTC
CATTGGCCTGCGTGAAGGCAAGAACCGTGAAGTGAAGAATATTCTTGGTGCGCTGGGCCTTACGGTCGGCCGCCTTATCC
GCGTTTCCTTTGGGCCATTCCAACTGGGCGATCTGGAAGAGGGCGCTGTTCGCGAGATCAAGGGGCGCACATTGCGCGAC
CAGCTTGGCGACAAGCTGATTGAGGAATCCGGTGCGGATTTTGATGCGCCGGTTCTCAATGAGTTTTCCAATGCCGCCGT
GCAGGGGCGCACGCGCCGTGAAATGGAAGAAGGCGAGCTGCCACAGGAAGGCGAACGCCGCCGCGCCCCGCGTGAGCGCG
AATGGATTTCCAGCACGGGCGAACGCCGTCGCGGACGCGAAGAGAAGACCGAAAAGGTAGAGCCGCGCCGTCGTGGCAAT
GCCAATGTGTGGATGGCTCCCGGCGCGCGCCCGAAGGGCGAAAAGGAGGCTGCAAAGCCTGCGCGCGTGGAACATCAGCA
ACCGCACCGTTCTGCAAAGTTCAGTGGCGATCTCCAGATGCGCCCGCGCCGCTTCAGCGAGGAAGAGCGCGGCGGCGAGG
AAAGCGGCGAACGCCGTTACAAACGCCCTGAAGGTCGTTTCGAGCGGGAAGGCGGCCGGCCGGATAATCGCGAAAAGTAC
GAAAAGCACGAGGGCGCTGGCAAGGAACGCCGCCCCGGCAAGCGTGAGCGCGCCGAACTGCGCAATGCGGAAGGCCAGAC
GACTGAACGCGGCAAAGGTGGTTCTGAGGGGCGCAAGCCCGGAAAGCCGGGTGGTCCGCGCAGCGAAGGCCGTTTTGGCG
GTGCCGACCGCGATACGCGCTCTGGTCCGCGTGGTTCCGGCCCGCGTGGTGCGGGTGATGGGCCGCGCCGCGGTCATGAC
GGAAAACCGGGCGGTAAGCCAGGTGGCAAGCCAACTGGCAGACCCGGTGGCAAACCGGGTACCAAGCCGGGTGGTGGGGG
CAGGTCGGGAGGCGGCGGTGCGGATCGTCGGCGGTAA

Upstream 100 bases:

>100_bases
GCTTTTCGCATGGGGTCCCATTTCGTGTATTGTTCGGGAAATTTCGCTCGCAAGCCATGGAGTGATTTGTTACTGCATAA
TTCCCGAAATCGAAACCGAT

Downstream 100 bases:

>100_bases
GTTTCGCGGGCGCGCGCTCGTAACACCGTCCACAAACGCCATTCGCCCGACCACGGACCGCACACGCGAAAGCCTGTTCA
ACATTCTTGCCCATAGTTTT

Product: hypothetical protein

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MRTELYGVPVANNLWRAMMAQGDAVTLLKGLYQMTTEDDNKGGKPPHGRKGHSDRPGRPDWDSRPRREGGDRDKPRKFGS
RGAPVEEETSERIAKRLARAGIASRREAETMIAAGRIAVNGKVLESPAVNVKRTDIITVDGKPLRQTERTRLWLYHKPAG
LVTTNRDPEGRPTVFEALPPEMPRVLSVGRLDINTEGLLLLTNDGGLSRVLELPSTGWLRRYRVRAHGKVTRQQLDELKN
GIAVDGVFYGSVEAELERVQGANVWISIGLREGKNREVKNILGALGLTVGRLIRVSFGPFQLGDLEEGAVREIKGRTLRD
QLGDKLIEESGADFDAPVLNEFSNAAVQGRTRREMEEGELPQEGERRRAPREREWISSTGERRRGREEKTEKVEPRRRGN
ANVWMAPGARPKGEKEAAKPARVEHQQPHRSAKFSGDLQMRPRRFSEEERGGEESGERRYKRPEGRFEREGGRPDNREKY
EKHEGAGKERRPGKRERAELRNAEGQTTERGKGGSEGRKPGKPGGPRSEGRFGGADRDTRSGPRGSGPRGAGDGPRRGHD
GKPGGKPGGKPTGRPGGKPGTKPGGGGRSGGGGADRRR

Sequences:

>Translated_598_residues
MRTELYGVPVANNLWRAMMAQGDAVTLLKGLYQMTTEDDNKGGKPPHGRKGHSDRPGRPDWDSRPRREGGDRDKPRKFGS
RGAPVEEETSERIAKRLARAGIASRREAETMIAAGRIAVNGKVLESPAVNVKRTDIITVDGKPLRQTERTRLWLYHKPAG
LVTTNRDPEGRPTVFEALPPEMPRVLSVGRLDINTEGLLLLTNDGGLSRVLELPSTGWLRRYRVRAHGKVTRQQLDELKN
GIAVDGVFYGSVEAELERVQGANVWISIGLREGKNREVKNILGALGLTVGRLIRVSFGPFQLGDLEEGAVREIKGRTLRD
QLGDKLIEESGADFDAPVLNEFSNAAVQGRTRREMEEGELPQEGERRRAPREREWISSTGERRRGREEKTEKVEPRRRGN
ANVWMAPGARPKGEKEAAKPARVEHQQPHRSAKFSGDLQMRPRRFSEEERGGEESGERRYKRPEGRFEREGGRPDNREKY
EKHEGAGKERRPGKRERAELRNAEGQTTERGKGGSEGRKPGKPGGPRSEGRFGGADRDTRSGPRGSGPRGAGDGPRRGHD
GKPGGKPGGKPTGRPGGKPGTKPGGGGRSGGGGADRRR
>Mature_598_residues
MRTELYGVPVANNLWRAMMAQGDAVTLLKGLYQMTTEDDNKGGKPPHGRKGHSDRPGRPDWDSRPRREGGDRDKPRKFGS
RGAPVEEETSERIAKRLARAGIASRREAETMIAAGRIAVNGKVLESPAVNVKRTDIITVDGKPLRQTERTRLWLYHKPAG
LVTTNRDPEGRPTVFEALPPEMPRVLSVGRLDINTEGLLLLTNDGGLSRVLELPSTGWLRRYRVRAHGKVTRQQLDELKN
GIAVDGVFYGSVEAELERVQGANVWISIGLREGKNREVKNILGALGLTVGRLIRVSFGPFQLGDLEEGAVREIKGRTLRD
QLGDKLIEESGADFDAPVLNEFSNAAVQGRTRREMEEGELPQEGERRRAPREREWISSTGERRRGREEKTEKVEPRRRGN
ANVWMAPGARPKGEKEAAKPARVEHQQPHRSAKFSGDLQMRPRRFSEEERGGEESGERRYKRPEGRFEREGGRPDNREKY
EKHEGAGKERRPGKRERAELRNAEGQTTERGKGGSEGRKPGKPGGPRSEGRFGGADRDTRSGPRGSGPRGAGDGPRRGHD
GKPGGKPGGKPTGRPGGKPGTKPGGGGRSGGGGADRRR

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=220, Percent_Identity=41.3636363636364, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI87081838, Length=179, Percent_Identity=32.9608938547486, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790453, Length=248, Percent_Identity=28.2258064516129, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788510, Length=222, Percent_Identity=29.7297297297297, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 65972; Mature: 65972

Theoretical pI: Translated: 11.07; Mature: 11.07

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTELYGVPVANNLWRAMMAQGDAVTLLKGLYQMTTEDDNKGGKPPHGRKGHSDRPGRPD
CCCCEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
WDSRPRREGGDRDKPRKFGSRGAPVEEETSERIAKRLARAGIASRREAETMIAAGRIAVN
CCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEC
GKVLESPAVNVKRTDIITVDGKPLRQTERTRLWLYHKPAGLVTTNRDPEGRPTVFEALPP
CEEECCCCCCEEECEEEEECCCCCCCCCCCEEEEEECCCCCEECCCCCCCCCCHHHCCCC
EMPRVLSVGRLDINTEGLLLLTNDGGLSRVLELPSTGWLRRYRVRAHGKVTRQQLDELKN
CCHHHHHCCEEEECCCCEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GIAVDGVFYGSVEAELERVQGANVWISIGLREGKNREVKNILGALGLTVGRLIRVSFGPF
CEEECEEEECCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
QLGDLEEGAVREIKGRTLRDQLGDKLIEESGADFDAPVLNEFSNAAVQGRTRREMEEGEL
CCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCC
PQEGERRRAPREREWISSTGERRRGREEKTEKVEPRRRGNANVWMAPGARPKGEKEAAKP
CCCHHHHCCCHHHHHHHHHHHHHCCHHHHHHHCCHHHCCCCCEEECCCCCCCCCHHHCCC
ARVEHQQPHRSAKFSGDLQMRPRRFSEEERGGEESGERRYKRPEGRFEREGGRPDNREKY
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHH
EKHEGAGKERRPGKRERAELRNAEGQTTERGKGGSEGRKPGKPGGPRSEGRFGGADRDTR
HHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SGPRGSGPRGAGDGPRRGHDGKPGGKPGGKPTGRPGGKPGTKPGGGGRSGGGGADRRR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRTELYGVPVANNLWRAMMAQGDAVTLLKGLYQMTTEDDNKGGKPPHGRKGHSDRPGRPD
CCCCEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
WDSRPRREGGDRDKPRKFGSRGAPVEEETSERIAKRLARAGIASRREAETMIAAGRIAVN
CCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEC
GKVLESPAVNVKRTDIITVDGKPLRQTERTRLWLYHKPAGLVTTNRDPEGRPTVFEALPP
CEEECCCCCCEEECEEEEECCCCCCCCCCCEEEEEECCCCCEECCCCCCCCCCHHHCCCC
EMPRVLSVGRLDINTEGLLLLTNDGGLSRVLELPSTGWLRRYRVRAHGKVTRQQLDELKN
CCHHHHHCCEEEECCCCEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GIAVDGVFYGSVEAELERVQGANVWISIGLREGKNREVKNILGALGLTVGRLIRVSFGPF
CEEECEEEECCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
QLGDLEEGAVREIKGRTLRDQLGDKLIEESGADFDAPVLNEFSNAAVQGRTRREMEEGEL
CCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCC
PQEGERRRAPREREWISSTGERRRGREEKTEKVEPRRRGNANVWMAPGARPKGEKEAAKP
CCCHHHHCCCHHHHHHHHHHHHHCCHHHHHHHCCHHHCCCCCEEECCCCCCCCCHHHCCC
ARVEHQQPHRSAKFSGDLQMRPRRFSEEERGGEESGERRYKRPEGRFEREGGRPDNREKY
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHH
EKHEGAGKERRPGKRERAELRNAEGQTTERGKGGSEGRKPGKPGGPRSEGRFGGADRDTR
HHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SGPRGSGPRGAGDGPRRGHDGKPGGKPGGKPTGRPGGKPGTKPGGGGRSGGGGADRRR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA