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The map label for this gene is virB6 [H]

Identifier: 225685931

GI number: 225685931

Start: 60967

End: 62010

Strand: Reverse

Name: virB6 [H]

Synonym: BMEA_B0068

Alternate gene names: 225685931

Gene position: 62010-60967 (Counterclockwise)

Preceding gene: 225685932

Following gene: 225685930

Centisome position: 5.23

GC content: 55.46

Gene sequence:

>1044_bases
ATGGTTAATCCTGTAATCTTTGAGTTCATCGGCACTTCGATCCACAACCAGTTGAACAATTACGTGACTATGGTGGCATC
CAACACCATGAATATGATTGCCACGACTGCTGTCCTCGCCGGTGGCCTCTACTATACCGCCATGGGCATATTGATGTCTG
TGGGGCGGATCGAAGGGCCGTTTTCGCAACTCGTCATAAGCTGTATTAAATTCATGCTGATTGCTGCTTTTGCGCTCAAT
ATCAGCACCTATTCGGAGTGGGTGATCGATACGGTGCACAACATGGAGTCCGGATTTGCCGACGCCTTTGCCGGCAATCA
CGGCACCCCTTCCAGCACGATCTACCAGACCCTCGACAATTCGTTGGGCAAGGGGTGGAACATCGCAGCCATGCTCTTTG
AGAAAGGCGATAATCGCGGCCTGACCCAGATCGTGCAGGGCTTTTCAGAACTGTTACTGTCATTCCTGGTAGCCGGCTCA
ACGCTTATCCTTGCAGGCCCGACTGGTGCGATGATCGTCGCAACCAATGCGGTGATCGCGATCCTGCTCGGAATCGGCCC
TCTCTTCATCCTCGCCCTTGGCTGGGCGCCGACAAGGGGCTTCTTCGATCGCTGGTTCGGGGCCATCGTCACATCGATCC
TTCAGGTCGCGCTTTTGTCGGCCGTGCTATCTATATCGAGTGCAATCTTCAGCCGCATGGTGGCGGCCATCAATTTGGCT
TCCGCAACACAAAGCACGCTCTTTTCCTGCCTCTCACTGACCGCTGTAACGATTGTCATGCCGTATATGATGTACAAGGT
CTATGAATACGGTGGCATCCTGGGCAGCAGCATATCGGCGGCCACGATCTCCCTCGGCTCACTTGCAGTCAATACCGCGA
AATCTGGTGGTGGCGCTATGACGAGCATATTCAGCGGATCATCCGGCGGCGGGGGTTCCGGCTCGGCGAAGGCGGGCGGG
GAAAGCAGTTATTCGGCTGGTGGCAACGCCATGTGGAGCCCGGCTTACCGGCAACACGTGCTCGGCCAGTTCAACAGGGA
TTAG

Upstream 100 bases:

>100_bases
ATCCATAATCATATTTGCAAATGAATACTTGATGAGTCTCTGGCTGGTTGGGGTAACCCCCAACCACGCCTAATCGGAAC
CGGGGTGAAGGAGTTTCGTG

Downstream 100 bases:

>100_bases
GGCCTTACACGCGGCGGCTTCGCCGCAGAATCCCGATCTTCGCGGCTACCCATGTCTGGCACATCATGGGCGACCTTTTT
GCAACGCTAAAGCGAAAATG

Product: protein virB6

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MVNPVIFEFIGTSIHNQLNNYVTMVASNTMNMIATTAVLAGGLYYTAMGILMSVGRIEGPFSQLVISCIKFMLIAAFALN
ISTYSEWVIDTVHNMESGFADAFAGNHGTPSSTIYQTLDNSLGKGWNIAAMLFEKGDNRGLTQIVQGFSELLLSFLVAGS
TLILAGPTGAMIVATNAVIAILLGIGPLFILALGWAPTRGFFDRWFGAIVTSILQVALLSAVLSISSAIFSRMVAAINLA
SATQSTLFSCLSLTAVTIVMPYMMYKVYEYGGILGSSISAATISLGSLAVNTAKSGGGAMTSIFSGSSGGGGSGSAKAGG
ESSYSAGGNAMWSPAYRQHVLGQFNRD

Sequences:

>Translated_347_residues
MVNPVIFEFIGTSIHNQLNNYVTMVASNTMNMIATTAVLAGGLYYTAMGILMSVGRIEGPFSQLVISCIKFMLIAAFALN
ISTYSEWVIDTVHNMESGFADAFAGNHGTPSSTIYQTLDNSLGKGWNIAAMLFEKGDNRGLTQIVQGFSELLLSFLVAGS
TLILAGPTGAMIVATNAVIAILLGIGPLFILALGWAPTRGFFDRWFGAIVTSILQVALLSAVLSISSAIFSRMVAAINLA
SATQSTLFSCLSLTAVTIVMPYMMYKVYEYGGILGSSISAATISLGSLAVNTAKSGGGAMTSIFSGSSGGGGSGSAKAGG
ESSYSAGGNAMWSPAYRQHVLGQFNRD
>Mature_347_residues
MVNPVIFEFIGTSIHNQLNNYVTMVASNTMNMIATTAVLAGGLYYTAMGILMSVGRIEGPFSQLVISCIKFMLIAAFALN
ISTYSEWVIDTVHNMESGFADAFAGNHGTPSSTIYQTLDNSLGKGWNIAAMLFEKGDNRGLTQIVQGFSELLLSFLVAGS
TLILAGPTGAMIVATNAVIAILLGIGPLFILALGWAPTRGFFDRWFGAIVTSILQVALLSAVLSISSAIFSRMVAAINLA
SATQSTLFSCLSLTAVTIVMPYMMYKVYEYGGILGSSISAATISLGSLAVNTAKSGGGAMTSIFSGSSGGGGSGSAKAGG
ESSYSAGGNAMWSPAYRQHVLGQFNRD

Specific function: The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice [H]

COG id: COG3704

COG function: function code U; Type IV secretory pathway, VirB6 components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trbL/virB6 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007688 [H]

Pfam domain/function: PF04610 TrbL [H]

EC number: NA

Molecular weight: Translated: 36161; Mature: 36161

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNPVIFEFIGTSIHNQLNNYVTMVASNTMNMIATTAVLAGGLYYTAMGILMSVGRIEGP
CCCHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FSQLVISCIKFMLIAAFALNISTYSEWVIDTVHNMESGFADAFAGNHGTPSSTIYQTLDN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCHHHHHHHHHH
SLGKGWNIAAMLFEKGDNRGLTQIVQGFSELLLSFLVAGSTLILAGPTGAMIVATNAVIA
HCCCCCCHHHHEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEHHHHHHH
ILLGIGPLFILALGWAPTRGFFDRWFGAIVTSILQVALLSAVLSISSAIFSRMVAAINLA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SATQSTLFSCLSLTAVTIVMPYMMYKVYEYGGILGSSISAATISLGSLAVNTAKSGGGAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHEECCCCCCCHH
TSIFSGSSGGGGSGSAKAGGESSYSAGGNAMWSPAYRQHVLGQFNRD
HHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MVNPVIFEFIGTSIHNQLNNYVTMVASNTMNMIATTAVLAGGLYYTAMGILMSVGRIEGP
CCCHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FSQLVISCIKFMLIAAFALNISTYSEWVIDTVHNMESGFADAFAGNHGTPSSTIYQTLDN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCHHHHHHHHHH
SLGKGWNIAAMLFEKGDNRGLTQIVQGFSELLLSFLVAGSTLILAGPTGAMIVATNAVIA
HCCCCCCHHHHEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEHHHHHHH
ILLGIGPLFILALGWAPTRGFFDRWFGAIVTSILQVALLSAVLSISSAIFSRMVAAINLA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SATQSTLFSCLSLTAVTIVMPYMMYKVYEYGGILGSSISAATISLGSLAVNTAKSGGGAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHEECCCCCCCHH
TSIFSGSSGGGGSGSAKAGGESSYSAGGNAMWSPAYRQHVLGQFNRD
HHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10940027 [H]