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The map label for this gene is nodW [H]

Identifier: 225685909

GI number: 225685909

Start: 38615

End: 39253

Strand: Direct

Name: nodW [H]

Synonym: BMEA_B0044

Alternate gene names: 225685909

Gene position: 38615-39253 (Clockwise)

Preceding gene: 225685908

Following gene: 225685911

Centisome position: 3.26

GC content: 55.24

Gene sequence:

>639_bases
ATGAACTGCGCATATGAACGCGATCCTGTCGTCTTTATCGTCGACGACGATCATTCCGTCCGCCTTGGTCTGGTGGACCT
GTTTGCCTCGATCGGATTAAAGGCGCTCTGTTTCGCCTCGGTGAATGAATTTCTCAAACATGCACGTGAAGAAGTCCCGG
CCTGCCTTATCCTCGATGTGCGTATGCCGGGTGAGAGCGGAACGGAATTTCATGCCAGAATGAAGGGGCTTGATATCCGC
TTGCCCGTGATTTTCATTACCGGCCATGGCGACATCGCCATGGGGGTCAAGGCGATCAAGGATGGTGCGATCGATTTTCT
GGCCAAACCCTTCCGCAACCAGGATCTTTTGGATGCAGTTCAACAGGCGATCCGGACAGACCGGAAGCGCCTGCGGGAGG
AACACAATCAACACAGGATCATTGCCCGCTATCAGACGCTCAACCAGGGTGAGCGCGCGGTTTTCAAACTCGTCGTTCAG
GGGCTCATGAACAAGCAGATCGCGGCTGAATTGGATGTGGCGGAAGTGACGGTCAAGGTCCGGCGCTCCCACCTCATGCA
CAAGATGAGAGCGAAGTCTCTGGCCGATCTGGTTCGCATGGCCACGGAACTGAACGCGCAACCGGTCAAAGAGCTTTGA

Upstream 100 bases:

>100_bases
CCATCGTCGAAAGCAGTGGCGGCACCATTGCCCTGGGGTCCACGACGCCCCATGGAACGACAATCCTGTTTGAAGTGCCA
ACGACACAGGAGACGGAGAT

Downstream 100 bases:

>100_bases
TGACAGCCTGCCTCAGGGCGCGCACCCCCATTGGTTCAGCTTTCCACCCATGTTTCAATTCTGGACGAAAGCCAGTGTCG
TACCCTGACAAAGCACATGT

Product: C4-dicarboxylate transport transcriptional regulatory protein dctR

Products: NADP; 2 glutathione [C]

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MNCAYERDPVVFIVDDDHSVRLGLVDLFASIGLKALCFASVNEFLKHAREEVPACLILDVRMPGESGTEFHARMKGLDIR
LPVIFITGHGDIAMGVKAIKDGAIDFLAKPFRNQDLLDAVQQAIRTDRKRLREEHNQHRIIARYQTLNQGERAVFKLVVQ
GLMNKQIAAELDVAEVTVKVRRSHLMHKMRAKSLADLVRMATELNAQPVKEL

Sequences:

>Translated_212_residues
MNCAYERDPVVFIVDDDHSVRLGLVDLFASIGLKALCFASVNEFLKHAREEVPACLILDVRMPGESGTEFHARMKGLDIR
LPVIFITGHGDIAMGVKAIKDGAIDFLAKPFRNQDLLDAVQQAIRTDRKRLREEHNQHRIIARYQTLNQGERAVFKLVVQ
GLMNKQIAAELDVAEVTVKVRRSHLMHKMRAKSLADLVRMATELNAQPVKEL
>Mature_212_residues
MNCAYERDPVVFIVDDDHSVRLGLVDLFASIGLKALCFASVNEFLKHAREEVPACLILDVRMPGESGTEFHARMKGLDIR
LPVIFITGHGDIAMGVKAIKDGAIDFLAKPFRNQDLLDAVQQAIRTDRKRLREEHNQHRIIARYQTLNQGERAVFKLVVQ
GLMNKQIAAELDVAEVTVKVRRSHLMHKMRAKSLADLVRMATELNAQPVKEL

Specific function: Member of the two-component regulatory system nodV/nodW probably involved in the regulation of the transcription of genes involved in the nodulation process [H]

COG id: COG4566

COG function: function code T; Response regulator

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790299, Length=115, Percent_Identity=36.5217391304348, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788550, Length=127, Percent_Identity=30.7086614173228, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23919; Mature: 23919

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNCAYERDPVVFIVDDDHSVRLGLVDLFASIGLKALCFASVNEFLKHAREEVPACLILDV
CCCCCCCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEE
RMPGESGTEFHARMKGLDIRLPVIFITGHGDIAMGVKAIKDGAIDFLAKPFRNQDLLDAV
ECCCCCCCHHHHHHCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
QQAIRTDRKRLREEHNQHRIIARYQTLNQGERAVFKLVVQGLMNKQIAAELDVAEVTVKV
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRSHLMHKMRAKSLADLVRMATELNAQPVKEL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNCAYERDPVVFIVDDDHSVRLGLVDLFASIGLKALCFASVNEFLKHAREEVPACLILDV
CCCCCCCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEE
RMPGESGTEFHARMKGLDIRLPVIFITGHGDIAMGVKAIKDGAIDFLAKPFRNQDLLDAV
ECCCCCCCHHHHHHCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
QQAIRTDRKRLREEHNQHRIIARYQTLNQGERAVFKLVVQGLMNKQIAAELDVAEVTVKV
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRSHLMHKMRAKSLADLVRMATELNAQPVKEL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH2; oxidized glutathione [C]

Specific reaction: NADPH2 + oxidized glutathione = NADP + 2 glutathione [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a disulfide as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2320582; 11157954; 12597275 [H]