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The map label for this gene is rbsK [H]

Identifier: 225685875

GI number: 225685875

Start: 2092

End: 3033

Strand: Direct

Name: rbsK [H]

Synonym: BMEA_B0007

Alternate gene names: 225685875

Gene position: 2092-3033 (Clockwise)

Preceding gene: 225685874

Following gene: 225685880

Centisome position: 0.18

GC content: 61.89

Gene sequence:

>942_bases
ATGAGCCATGGAGAAGCCCCGTTGAAGATTTTCGTTTTCGGCAGTGTGAATGTGGATGTAAGCGCCCGAATGGCTGCCCT
GCCGCGGCCGGAGCAGACGGTAAACGCATCCGGCTATGGCATCGGGCTGGGTGGCAAAGGAGCCAATCAGGCGGTTGCGG
TGGCAAAACTTGGCGGGGCAATCCGATTTGTCGGCGCGGTCGGCCATGATGCCTTTGGCGAACTGGCCTTAAAGCAGATG
CGCGAGTTTGGGCTGGATACCGGCAGCGTGCGCGTGATCGATGACGTCGATACAGGCATGGCGATCATCCAGGTGGAGGA
AACCGGGCAGAACACGATTGCGGTCTGTGCTGGCGCCAATGCGCGCTGCTCGTCAGCCGATATTGATGCTTATGGCGCTG
ATATTGCCAAGGCAAGGATTACGCTTTTGCAGCGCGAAGTGCCGCATGAAGCCAATCTGGCCGTTGCGAAAGCCGTGCGG
GCAGCGGGTGGAACCGTCCTGCTCGACCCGGCCCCGGTGGGGGATGCAAGCCAGATGGCCGATCTTATCGCCCTGAGCGA
CATCATTTCGCCCAACGAGACGGAAGCCGCTGAAATCACCGGCATTGAGCCGACCGACCTCGCTTCGGCGGAAGCGGCGG
GGCGCAAGCTTCTGGAGCGCGGCCCGAAGATCGTCATCCTCAAGCTTGGAAGCCGTGGCGCGCTGCTGGTAACGGCGGAT
GAGGTGAAACACTTCACGCCGTTCAAGGTAAAGGTGGTGGATACGGTTGCAGCCGGTGACAGTTTCAACGGCGGCTTTGC
CGTTGCTTTCTCGCAGGCGCGGCCCTTGCATGATTGCGTGCGGTATGGTTCGGCGGCGGGCGCGATTGCGGTTACGCGGG
TTGGCGCAGGCGCTGCCGCGCCAACCGCGCGTGAGGTTGAGGAACTCATCGGGCGCGCTTGA

Upstream 100 bases:

>100_bases
CCTCAGCGGCTTTTCATGGGTTGTGTATGAAAACGGGCTGGCGTGGAAGTTTTTCCCGTTCGCGGCTATGGTGCGGCAAT
ATTGATTTCAAGCAGATGCC

Downstream 100 bases:

>100_bases
GCTTCCAGCTTGTTTCAAAAGAAAAGCCGCGCAAGGTTTGGCCTGCGCGGCGTTTCTGTGAACCAGCCAATACCGGTCAA
AGCGTCGCCAGACGCTCCGT

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSHGEAPLKIFVFGSVNVDVSARMAALPRPEQTVNASGYGIGLGGKGANQAVAVAKLGGAIRFVGAVGHDAFGELALKQM
REFGLDTGSVRVIDDVDTGMAIIQVEETGQNTIAVCAGANARCSSADIDAYGADIAKARITLLQREVPHEANLAVAKAVR
AAGGTVLLDPAPVGDASQMADLIALSDIISPNETEAAEITGIEPTDLASAEAAGRKLLERGPKIVILKLGSRGALLVTAD
EVKHFTPFKVKVVDTVAAGDSFNGGFAVAFSQARPLHDCVRYGSAAGAIAVTRVGAGAAAPTAREVEELIGRA

Sequences:

>Translated_313_residues
MSHGEAPLKIFVFGSVNVDVSARMAALPRPEQTVNASGYGIGLGGKGANQAVAVAKLGGAIRFVGAVGHDAFGELALKQM
REFGLDTGSVRVIDDVDTGMAIIQVEETGQNTIAVCAGANARCSSADIDAYGADIAKARITLLQREVPHEANLAVAKAVR
AAGGTVLLDPAPVGDASQMADLIALSDIISPNETEAAEITGIEPTDLASAEAAGRKLLERGPKIVILKLGSRGALLVTAD
EVKHFTPFKVKVVDTVAAGDSFNGGFAVAFSQARPLHDCVRYGSAAGAIAVTRVGAGAAAPTAREVEELIGRA
>Mature_312_residues
SHGEAPLKIFVFGSVNVDVSARMAALPRPEQTVNASGYGIGLGGKGANQAVAVAKLGGAIRFVGAVGHDAFGELALKQMR
EFGLDTGSVRVIDDVDTGMAIIQVEETGQNTIAVCAGANARCSSADIDAYGADIAKARITLLQREVPHEANLAVAKAVRA
AGGTVLLDPAPVGDASQMADLIALSDIISPNETEAAEITGIEPTDLASAEAAGRKLLERGPKIVILKLGSRGALLVTADE
VKHFTPFKVKVVDTVAAGDSFNGGFAVAFSQARPLHDCVRYGSAAGAIAVTRVGAGAAAPTAREVEELIGRA

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=301, Percent_Identity=33.5548172757475, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI32484973, Length=252, Percent_Identity=27.3809523809524, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI32484975, Length=252, Percent_Identity=27.3809523809524, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1790193, Length=304, Percent_Identity=40.1315789473684, Blast_Score=188, Evalue=4e-49,
Organism=Escherichia coli, GI87081971, Length=278, Percent_Identity=25.5395683453237, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082343, Length=308, Percent_Identity=26.9480519480519, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788491, Length=290, Percent_Identity=21.7241379310345, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=302, Percent_Identity=36.7549668874172, Blast_Score=181, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6319884, Length=335, Percent_Identity=27.7611940298507, Blast_Score=117, Evalue=3e-27,
Organism=Drosophila melanogaster, GI20128807, Length=307, Percent_Identity=34.2019543973941, Blast_Score=137, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24583886, Length=301, Percent_Identity=29.9003322259136, Blast_Score=106, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31949; Mature: 31817

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHGEAPLKIFVFGSVNVDVSARMAALPRPEQTVNASGYGIGLGGKGANQAVAVAKLGGA
CCCCCCCEEEEEEEECCCCHHHHHHCCCCCCHHCCCCCEEEECCCCCCCCEEEEEHHCCE
IRFVGAVGHDAFGELALKQMREFGLDTGSVRVIDDVDTGMAIIQVEETGQNTIAVCAGAN
EEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCCCEEEEEECCC
ARCSSADIDAYGADIAKARITLLQREVPHEANLAVAKAVRAAGGTVLLDPAPVGDASQMA
CCCCCCCCCHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCCCCCHHHHH
DLIALSDIISPNETEAAEITGIEPTDLASAEAAGRKLLERGPKIVILKLGSRGALLVTAD
HHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCEEEEEHH
EVKHFTPFKVKVVDTVAAGDSFNGGFAVAFSQARPLHDCVRYGSAAGAIAVTRVGAGAAA
HHCCCCCEEEEEEEEEECCCCCCCCEEEEECCCCCHHHHHHHCCCCCEEEEEEECCCCCC
PTAREVEELIGRA
CCHHHHHHHHCCC
>Mature Secondary Structure 
SHGEAPLKIFVFGSVNVDVSARMAALPRPEQTVNASGYGIGLGGKGANQAVAVAKLGGA
CCCCCCEEEEEEEECCCCHHHHHHCCCCCCHHCCCCCEEEECCCCCCCCEEEEEHHCCE
IRFVGAVGHDAFGELALKQMREFGLDTGSVRVIDDVDTGMAIIQVEETGQNTIAVCAGAN
EEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCCCEEEEEECCC
ARCSSADIDAYGADIAKARITLLQREVPHEANLAVAKAVRAAGGTVLLDPAPVGDASQMA
CCCCCCCCCHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCCCCCHHHHH
DLIALSDIISPNETEAAEITGIEPTDLASAEAAGRKLLERGPKIVILKLGSRGALLVTAD
HHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCEEEEEHH
EVKHFTPFKVKVVDTVAAGDSFNGGFAVAFSQARPLHDCVRYGSAAGAIAVTRVGAGAAA
HHCCCCCEEEEEEEEEECCCCCCCCEEEEECCCCCHHHHHHHCCCCCEEEEEEECCCCCC
PTAREVEELIGRA
CCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]